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How to React to the Subprime Crisis? - The Impact of an Interest Rate Freeze on Residential Mortgage Backed  [PDF]
Julia Hein, Thomas Weber
Journal of Service Science and Management (JSSM) , 2009, DOI: 10.4236/jssm.2009.24035
Abstract: Several policy options have been discussed to mitigate the current subprime mortgage crisis. This paper analyses an interest rate freeze on adjustable rate mortgages as one possible reaction. In particular, the implications on Residential Mortgage Backed Securities (RMBS) are studied. We examine shifts in the underlying portfolio’s discounted cash flow distributions as well as changes in the payment profile of RMBS-tranches. We show that the positive effects of a rate freeze, e.g. less foreclosures and a stabilizing housing market, can outweigh the negative effect of lower interest income such that investors might be better off.
Genetic Background May Confer Susceptibility to PTC in Benign Multinodular Thyroid Disease  [PDF]
Sivatharsiny Thavarajah, Frank Weber
Journal of Cancer Therapy (JCT) , 2012, DOI: 10.4236/jct.2012.36128
Abstract: Purpose: The incidence of hyperplastic thyroid nodular disease has been consistently rising over the last decades. In addition, unsuspected papillary thyroid carcinoma (PTC) can be found in up to 34% of patients operated for benign thyroid lesions. PTC tends to occur multi-focally and is commonly of polyclonal origin. We set out to test the hypothesis that in benign thyroid disease, a unique genetic signature can already be identified in the benign pathology, which is associated with a susceptibility of the thyroid tissue to neoplastic transformation in the context of additional growth promoting stimuli. Patients and Methods: We obtained a set of 23 samples from patients with multinodular goiter (MNG), 12 of whom also harbored an unsuspected PTC. We used global gene expression analysis to evaluate for dissimilarities in the gene expression patterns between these two groups. We also compared these patterns to the profiles of 3 normal thyroid and 7 PTC samples. Results: We were able to accurately distinguish between hyperplastic nodules of patients with multinodular goiter and those that were associated with a PTC. One of the strongest differentially expressed genes, CDC42, has been implicated to respond to environmental factors such as UVB radiation and might point to novel factors contributing to PTC genesis in the setting of pre-existing benign proliferative disease. Conclusion: While the comparison between histologically identical samples cannot distinguish the two groups of goiters, unsupervised or supervised approaches allowed us to identify a molecular signature associated with PTC susceptibility in multinodular goiter.
A Reconfigurable Network-on-Chip Datapath for Application Specific Computing  [PDF]
Joshua Weber, Erdal Oruklu
Circuits and Systems (CS) , 2013, DOI: 10.4236/cs.2013.42025
Abstract:

This paper introduces a new datapath architecture for reconfigurable processors. The proposed datapath is based on Network-on-Chip approach and facilitates tight coupling of all functional units. Reconfigurable functional elements can be dynamically allocated for application specific optimizations, enabling polymorphic computing. Using a modified network simulator, performance of several NoC topologies and parameters are investigated with standard benchmark programs, including fine grain and coarse grain computations. Simulation results highlight the flexibility and scalability of the proposed polymorphic NoC processor for a wide range of application domains.

Dynamic Knowledge—A Century of Evolution  [PDF]
Georg F. Weber
Sociology Mind (SM) , 2013, DOI: 10.4236/sm.2013.34036
Abstract:

The discovery of non-linear systems dynamics has impacted concepts of knowledge to ascribe to it dynamic properties. It has expanded a development that finds its roots more than hundred years ago. Then, certainty was sought in systems of scientific insight. Such absolute certainty was inevitably static as it would be irrevocable once acquired. Although principal limits to the obtainability of knowledge were defined by scientific and philosophical advances from the 1920s through the mid-twentieth century, the knowledge accessible within those boundaries was considered certain, allowing detailed description and prediction within the recognized limits. The trend shifted away from static theories of knowledge with the discovery of the laws of nature underlying non-linear dynamics. The gnoseology of complex systems has built on insights of non-periodic flow and emergent processes to explain the underpinnings of generation and destruction of information and to unify deterministic and indeterministic descriptions of the world. It has thus opened new opportunities for the discourse of doing research.

Abstammungsbewertung der zuchtstiere propektiv und retrospektiv
F Weber
Genetics Selection Evolution , 1976, DOI: 10.1186/1297-9686-8-2-303b
Abstract:
Prüfungen in tierzucht für studenten
F Weber
Genetics Selection Evolution , 1977, DOI: 10.1186/1297-9686-9-1-134d
Abstract:
Praktische aspekte von rassenvergleichsversuchen beim rind
F Weber
Genetics Selection Evolution , 1975, DOI: 10.1186/1297-9686-7-2-234a
Abstract:
La stérilité des males dans les races caprines suisses sans cornes
W Weber
Genetics Selection Evolution , 1969, DOI: 10.1186/1297-9686-1-4-379
Abstract:
Report. The UICC Familial Cancer and Prevention Project 1991-2003
Walter Weber
Hereditary Cancer in Clinical Practice , 2004, DOI: 10.1186/1897-4287-2-3-151
Abstract: The operational definition of familial cancer is: two or more affected first degree relatives. This definition applies to 10% to 30% of all cancer patients.The UICC Familial Cancer and Prevention Project was launched in 1991 by Dr. K. Aoki, Dr. M.M. Burger and Dr. W. Weber in Lugano, Switzerland. It promoted familial cancer control worldwide until 2003. The activities were:1. Establishment of nodal points in Australia (D.J.B. St. John, R. Scott), Egypt (R. Bedwani), Japan (J. Utsunomiya), Poland (J. Lubinski), USA (J.J. Mulvihill) and Switzerland (M.M. Burger, W. Weber).2. Establishment of the Familial Cancer Database - FaCD http://www.facd.info webcite.3. A simple family history questionnaire has been developed for comparisons of family cancer data in different countries.4. Ten project meetings were held in Brazil, India, Italy, Japan 2×, USA 2× and Switzerland 3×.5. Four educational seminars took place (in Belgium, Israel and Switzerland 2×).6. The first international symposium was held in Japan.7. An international research conference took place in Switzerland.8. An international symposium on familial cancer and prevention in 1997 in Kobe, Japan.9. Combined Project and Oncology Conferences in 1999 in Karachi, Pakistan, in Alexandria, Egypt, and in 2001 in Beijing, China.10. Initiation of family studies in Poland and neighbouring countries.11. Pilot study: Cancer in first-degree relatives of Latin American women with cervical cancer.12. International conference on familial cancer, 5-7 June 2003, Oklahoma City, USA.The ending UICC project is transformed into an international network with minimal infrastructure: Familial Cancer Prevention, Detection and Care Network (FCPDCN). The existing nodal points continue to work as framework of an informal and open communication system: Asia: J. Utsunomiya [email protected], Australia: R. Scott [email protected], Europe + Africa: J. Lubinski [email protected] and W. Weber [email protected], USA: J.J. Mulv
Notas sobre o CNE e a qualidade do ensino superior
Weber, Silke;
Educa??o & Sociedade , 2002, DOI: 10.1590/S0101-73302002008000006
Abstract: this paper brings forth some notes upon the action of the brazilian council of education (cne), especially at the chamber of higher education, since its creation, in 1996, through law number 9131/1996. the cne is conceived as a social space that establishes direct links between agents of the political society, specifically the government, and segments of the civil society as for issues related to education. its institutional dynamics ? proposals and conflicts aroused ?, as well as some its possible repercussions not only on higher education, more particularly on the increase of offers of graduate and specialization courses, but also on teacher training are briefly highlighted.
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