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Search Results: 1 - 10 of 4577 matches for " Wagner "
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Hybrid Decision Models in Non-Proportional Reinsurance  [PDF]
Maik Wagner
Technology and Investment (TI) , 2010, DOI: 10.4236/ti.2010.11008
Abstract: Over the past years, risk measurement and therewith risk measures became more and more important in economics. While in the past risk measures were already adopted at the deposit of credit and shareholders equity, the approach now generates two hybrid decision models and applies them to the reinsurance business. The two introduced models implement a convex combination of risk measures and with it provide the possibility of modelling risk attitudes. By doing that, for the two hybrid decision models on the one hand can be shown, which risk attitude leads to the acceptance of a reinsurance contract and on the other hand, a deductible of which height an insurer is willing to undertake. Hence the possibility exists to identify the risk attitude of an insurer. In return, due to the knowledge of risk attitudes, under similar conditions the possibility arises to establish recommendations about the extent of the deductible at reinsurance contracts.
Questioning the Weber Thesis: Capitalist Ethics and the Hebrew Bible?  [PDF]
Sigmund Wagner-Tsukamoto
Sociology Mind (SM) , 2012, DOI: 10.4236/sm.2012.21001
Abstract: Weber’s thesis proposed that it was ascetic Protestantism which supported the emergence of modern capitalism in 17th and 18th century Europe, and that this was a completely new and unique phenomenon in the history of mankind up to that point in time. This paper casts doubt on the Weber thesis by examining findings from an economic reconstruction of the Hebrew Bible, and proposing that modern capitalism the way Weber understood it is already visible in the ancient religious text of the “Hebrew Bible”. By means of institutional economic reconstruction, I show that the Hebrew Bible and particularly the stories involving Jacob and Joseph reveal a conceptual structure that can be compared with ideas of modern constitutional and institutional economics. Through this reconstruction, I find myself in agreement with one of Weber’s early but largely forgotten adversaries, Werner Sombart, who suggested, in a behavioral tradition, that other religions, and more specifically Jewish thought, contributed to the emergence of modern capitalism long before the advent of Protestantism.
Surgical Flap and Graft Reconstruction Workshop for Dermatology Residents  [PDF]
Brandon Goodwin, Richard Wagner
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2015, DOI: 10.4236/jcdsa.2015.52011
Abstract: Background: Traditional models for teaching surgical principles focus primarily on the apprenticeship theory; however there has been a trend in surgical education to certifying competency in a simulation environment prior to working with patients. Many surgical models emphasize learning the technical and manual dexterity skills necessary to be a surgeon, yet few focus on obtaining the theoretical and abstract skills needed for planning complex cutaneous surgical repairs with flaps and grafts. We developed and evaluated a novel surgical flaps and grafts workshop for residents through the Department of Dermatology. Methods: Participants received a 60 minute PowerPoint lecture focusing on the basic principles of cutaneous repair with flaps and grafts, with examples and explanation of each of the four main types of flaps and grafts. The participants then received nine photocopies of Mohs micrographic surgery defects with instructions to design three repairs, focusing on functional and aesthetic outcome. Hypothetical and actual repair designs were then discussed in an open forum format. Anonymous surveys administered to 11 dermatology residents assessed their knowledge level, confidence level, and likelihood of using flaps and grafts pre- and post-workshop using Likert scales. Overall experience was also assessed. A paired sample Wilcoxon Signed Rank Test was used for analysis, since the data was non-parametrically distributed. Results: There was a statistically significant increase in confidence performing flaps post workshop (p = 0.0469). There was also an increase in knowledge of flaps and grafts, confidence in planning flaps and grafts, and confidence in performing grafts post workshop, but these findings did not reach statistical significance. The workshop had no effect on expected future use of flaps and grafts. Conclusions: The surgical workshop is a novel simulation teaching tool for learning basic principles and design of flaps and grafts in cutaneous surgery.
Production of MgO-X Refractory Material with Cellular Matrix by Colloidal Processing  [PDF]
Wagner da Silveira, Guido Falk
Low Carbon Economy (LCE) , 2012, DOI: 10.4236/lce.2012.323012
Abstract: The production in the siderurgy and foundry industry has changed considerably in the past years. Despite the new technologies and process, the use of magnesia carbon refractory remains constant. Namely the magnesia carbon refractory is widely used due low-priced cost, high refractivity, excellent corrosion resistance, thermal shock resistance, low thermal expansion, high slag penetration resistance and low wettability. The main disadvantages of use magnesia carbon refractories are the high carbon oxidation susceptibility and the formation CO and CO2 gases. As a result, tonne of CO and CO2 are expelled to the atmosphere. The use of open cell carbon-foam magnesia composite for refractory application can offer a substitute for the traditional refractory material since the high carbon content can be minored and the low mechanical strength and poor oxidation resistance of these materials can be improved.
Hermeneutical Theodolite of Requirements: Evaluating and Revealing the Quality Grades of Software Requirements and of Domain of Application  [PDF]
Wagner Varalda, ítalo Santiago Vega
Journal of Computer and Communications (JCC) , 2018, DOI: 10.4236/jcc.2018.65004
Abstract: Throughout the development of software, during Requirements Engineering activities, software requirements dynamically and constantly evolve and mature from an “identified” stage to an “approved” stage. This evolution takes place individually for each requirement, in a very particular way, because it depends on the level of understanding that the requirements engineer reaches in relation to it. How, then, to monitor the evolution of each software requirement? How to know the quality of each software requirement? How to measure the level of understanding and difficulty that the requirements engineer has in relation to each software requirement? This paper aims to present a proposal to answer these questions through the use of an instrument developed specifically to assess and reveal the quality grades of each software requirement and also to assess and reveal that the levels of understanding and of difficulty of the requirements engineer is in relation to each software requirement. This instrument was called the Hermeneutical Theodolite of Requirements, which also can be applied to evaluate that the levels of understanding and of difficulty of the requirements engineer is in relation to the domain of application, essential input artifact and primordial to the specification of the requirements of software.
Hermeneutical Elicitation of Requirements: A Technical Perspective to Improve the Conception of the Software Requirements  [PDF]
Wagner Varalda, ítalo Santiago Vega
Journal of Computer and Communications (JCC) , 2018, DOI: 10.4236/jcc.2018.69010
Abstract: In order to develop quality software that meets the originals needs of its users, it is necessary to perform the Requirements Engineering, so that the software context to be developed is identified, examined and specified properly. However, there is a problem that is increasingly in debate: the difficulty in understanding and establishing the purpose of the software to be developed, as pointed out by important researches in the area, such as the Chaos Report, which indicates that only 29% of software projects are successful, and the Software Engineering Institute, which points out software requirements as a critical factor for the success of software engineering and that deficiencies in this dimension are the main causes of software project failures. This article presents a proposal to address this problem through the use of the Hermeneutical Elicitation of Requirements, which is the conceptual adequacy of some hermeneutical methods in a technical approach that assists the requirements engineer to conceive better of the software requirements. In this way, the software engineer will be better able to develop the software to better meet the needs of its end users and sponsors.
Skew Polynomial Extensions over Zip Rings
Wagner Cortes
International Journal of Mathematics and Mathematical Sciences , 2008, DOI: 10.1155/2008/496720
Abstract: In this article, we study the relationship between left (right) zip property of and skew polynomial extension over , using the skew versions of Armendariz rings.
Camptothecin-Based Regimens for Treatment of Ewing Sarcoma: sPast Studies and Future Directions
Lars Wagner
Sarcoma , 2011, DOI: 10.1155/2011/957957
Abstract: New therapies are needed to improve survival for patients with Ewing sarcoma. Over the past decade, camptothecin agents such as topotecan and irinotecan have demonstrated activity against Ewing sarcoma, especially in combination with alkylating agents. Previous studies have shown camptothecin-based combinations to be tolerable outpatient strategies that are attractive for salvage therapy. This paper highlights important issues related to drug dosing, schedule of administration, pharmacokinetics, toxicity, and activity of commonly used camptothecin-based regimens. Also discussed are strategies for incorporating these regimens into therapy for newly diagnosed patients, including several potential possibilities for combination with targeted agents.
Cooperation is Fleeting in the World of Transposable Elements
Andreas Wagner
PLOS Computational Biology , 2006, DOI: 10.1371/journal.pcbi.0020162
Abstract: Composite transposons are key vehicles for the worldwide spreading of genes that allow bacteria to survive toxic compounds. Composite transposons consist of two smaller transposable elements called insertion sequences (ISs), which flank the genes that permit such survival. Each IS in a composite transposon can either transpose alone, selfishly, or it can transpose cooperatively, jointly with the other IS. Cooperative transposition can enhance an IS's chance of survival, but it also carries the risk of transposon destruction. I use game theory to show that the conditions under which cooperative transposition is an evolutionarily stable strategy (ESS) are not biologically realistic. I then analyze the distribution of thousands of ISs in more than 200 bacterial genomes to test the following prediction of the game-theoretical model: if cooperative transposition was an ESS, then the closely spaced ISs that characterize composite transposons should be more abundant in genomes than expected by chance. The data show that this is not the case. Cooperativity can only be maintained in a transitional, far-from-equilibrium state shortly after a selection pressure first arises. This is the case in the spreading of antibiotic resistance, where we are witnessing a fleeting moment in evolution, a moment in which cooperation among selfish DNA molecules has provided a means of survival. Because such cooperation does not pay in the long run, the vehicles of such survival will eventually disappear again. My analysis demonstrates that game theory can help explain behavioral strategies even for mobile DNA.
Normal and pathological bone development controlled by the AP-1 transcription factor complex
EF Wagner
Arthritis Research & Therapy , 2001, DOI: 10.1186/ar169
Abstract: Since Fos proteins need Jun proteins to activate transcription, we investigated the function of c-Jun in bone cells using the cre/loxP system. Chondrocyte-specific inactivation using col2A1-cre transgenic mice results in severe scoliosis caused by failure of intevertebral disk formation and abnormal vertebral arch development, suggesting that c-jun is a novel regulator of sklerotomal differentiation.
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