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Search Results: 1 - 10 of 11565 matches for " Wagner Daniela "
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Das Ende der Welt ist nicht das Ende der Tugend. Tintorettos Jüngstes Gericht für Venedig
Wagner, Daniela
RIHA Journal , 2012,
Abstract: Tintoretto's Last Judgement of Madonna dell'Orto in Venice includes an unusual detail: the scene of a flood. While Tintoretto refers to Michelangelo's Sixtine Chapel Judgement in form and structure, the depiction of masses of water or the small boat riding down the stream seems unprecedented in that context. As no attempts have been made so far to interpret these unique details, the aim of this article is to set forth and put up for discussion a new approach to Tintoretto's Last Judgement. In particular, it argues that these details reflect the virtuous ideals of the Republic; this suggests the conclusion that Tintoretto has created a judgement for the people of Venice.
Two years experience with quality assurance protocol for patient related Rapid Arc treatment plan verification using a two dimensional ionization chamber array
Daniela Wagner, Hilke Vorwerk
Radiation Oncology , 2011, DOI: 10.1186/1748-717x-6-21
Abstract: Measurements were done to determine the dependence between response of 2D ionization chamber array, beam direction, and field size. Also the reproducibility of the measurements was checked. For the patient related verifications the original patient Rapid Arc treatment plan was projected on CT dataset of the MatriXX and the dose distribution was calculated. After irradiation of the Rapid Arc verification plans measured and calculated 2D dose distributions were compared using the gamma evaluation method implemented in the measuring software OmniPro (version 1.5, IBA, Schwarzenbruck, Germany).The dependence between response of 2D ionization chamber array, field size and beam direction has shown a passing rate of 99% for field sizes between 7 cm × 7 cm and 24 cm × 24 cm for measurements of single arc. For smaller and larger field sizes than 7 cm × 7 cm and 24 cm × 24 cm the passing rate was less than 99%. The reproducibility was within a passing rate of 99% and 100%. The accuracy of the whole process including the uncertainty of the measuring system, treatment planning system, linear accelerator and isocentric laser system in the treatment room was acceptable for treatment plan verification using gamma criteria of 3% and 3 mm, 2D global gamma index.It was possible to verify the 2D dose distribution and MU of Rapid Arc treatment plans using the MatriXX. The use of the MatriXX for Rapid Arc treatment plan verification in clinical routine is reasonable. The passing rate should be 99% than the verification protocol is able to detect clinically significant errors.Rapid Arc radiotherapy technology from Varian Medical Systems is one of the most complex delivery systems currently available, and achieves an entire intensity-modulated radiation therapy (IMRT) treatment in a single gantry rotation around the patient. Three dynamic parameters can be continuously varied to create IMRT dose distributions: speed of rotation, beam shaping aperture and delivery dose rate [1]. The variat
Evaluation of an Intervention Program to Foster Self-Regulated Learning and Academic Achievement in Latin Instruction
Daniela Wagner,Franziska Perels
ISRN Education , 2012, DOI: 10.5402/2012/848562
Sentir-se bem em família: um desafio frente à diversidade
Wagner, Adriana,Levandowski, Daniela Centenaro
Textos & Contextos (Porto Alegre) , 2008,
Abstract: No presente trabalho, discutimos acerca das crises da família, apresentando informa es que demonstram a diversidade de configura es familiares existentes no contexto brasileiro atual, tais como separa es, divórcios, uni es consensuais, casais sem filhos, recasamentos, dentre outras. Desse modo, refletimos acerca da crise do modelo tradicional de família e n o da institui o família, questionando: Como sentir-se bem em família frente a tal pluralidade? Sugerimos, ent o, alguns aspectos que devem ser observados para atender as demandas dessas novas famílias e, conseqüentemente, promover a saúde de seus membros.
Impact of different leaf velocities and dose rates on the number of monitor units and the dose-volume-histograms using intensity modulated radiotherapy with sliding-window technique
Hilke Vorwerk, Daniela Wagner, Clemens F Hess
Radiation Oncology , 2008, DOI: 10.1186/1748-717x-3-31
Abstract: IMRT plans for different LVs from 1.0 cm/sec to 10.0 cm/sec and different DRs from 100 MU/min to 600 MU/min for two patients with prostate cancer and two patients with squamous cell cancer of the scalp (SCCscalp) were calculated using the same "optimal fluence map". For each field the number of monitor units, the dose volume histograms and the differences in the "actual fluence maps" of the fields were analysed.With increase of the DR and decrease of the LV the number of monitor units increased and consequentially the radiation dose given to the OAR. In particular the serial OARs of patients with SCCscalp, which are located outside the end position of the leafs and inside the open field, received an additional dose of a higher DR and lower LV is used.For best protection of organs at risk, a low DR and high LV should be applied. But the consequence of a low DR is both a long treatment time and also that a LV of higher than 3.0 cm/sec is mechanically not applicable. Our recommendation for an optimisation of the discussed parameters is a leaf velocity of 2.5 cm/sec and a dose rate of 300–400 MU/min (prostate cancer) and 100–200 MU/min (SCCscalp) for best protection of organs at risk, short treatment time and number of monitor units.Intensity modulated radiotherapy (IMRT) offers a method of delivering a radiation dose conformed to the shape of targets while minimizing the dose to the surrounding tissue and nearby critical organs. For IMRT with sliding window technique, modern IMRT planning systems incorporate many control system limitations in their leaf sequencing algorithms, such as limits for the leaf velocity (LV), the actual dose rate (DR), leakage, dynamic leaf gap, transmission and a minimum leaf gap (mechanical distance between the tops of the MLCs). Incorporation of control system limitations into the leaf sequencing algorithm results in decreased discrepancies between planned and delivered IMRT fields. Dynamic sliding-window leaf sequences can be produced, whi
In-vitro analysis of the microbicidal activity of 6 contact lens care solutions
Hildebrandt Claudia,Wagner Daniela,Kohlmann Thomas,Kramer Axel
BMC Infectious Diseases , 2012, DOI: 10.1186/1471-2334-12-241
Abstract: Background Contact lens-related infections are often associated with inadequate contact lens hygiene, and therefore, contact lens care products should be able to sufficiently minimise the amount of pathogens that are responsible for these infections. In 2001, the EN ISO 14729 was introduced to ensure adequate disinfection efficacy of contact lens care solutions, but this norm has recently been criticised. Methods In this study, six frequently used contact lens care solutions were retested according to the Stand Alone Test of the EN ISO 14729 (2001). The Stand Alone Test is a quantitative suspension test. In addition, the products were tested in a modified setting adding an organic load. The load was a mixture of human blood serum, lysozyme, and mucine, which resembles tear fluid. Results The criteria of the Stand Alone Test recommended in EN ISO 14729 were only met by Aosept Plus. This 3% hydrogen-peroxide-based contact lens care solution attained a reduction factor of > 5 log units for bacteria and > 4 for fungi in all cases. Two further contact lens care solutions, Blue Vision and Optifree Replenish, met the criteria of a reduction factor of > 3 log units for bacteria and > 1 log unit for fungi, but only in the presence of artificial tear fluid. The three remaining products did not exhibit adequate disinfecting efficacy, at least against one of the tested microorganisms. Conclusions Through the observation that the artificial tear fluid used in this study influences the disinfecting efficacy of contact lens care solutions, especially that of multi-purpose solutions, in a different way than does albumin, mucine, or even the organic load suggested in EN ISO 14729, it becomes obvious that the test conditions in the EN ISO 14729 should be revised in order to create more realistic conditions, e.g., by using a more realistic artificial tear fluid. Furthermore, we suggest adapting the EN ISO 14729 to the European test hierarchy for chemical disinfectants and antiseptics, which consists of three test phases and also requests meeting stricter criteria in order to pass the test. Unless the test conditions guarantee a sufficient reduction of potential pathogens, the risk of contact lens-related microbial keratitis and other infections will remain for the users.
A Framework for Designing Training Programs to Foster Self-Regulated Learning and Text Analysis Skills
Daniela Wagner,Sandra D?rrenb?cher,Franziska Perels
Education Research International , 2014, DOI: 10.1155/2014/510342
Abstract: The study’s aim was to develop an intervention program and to evaluate its contribution to students’ self-regulated learning (SRL) and text analysis skills. In a student-focused training approach, the students themselves acquired the training strategies, whereas in the teacher-focused training, the teachers were enabled to explicitly impart these strategies to their students. In order to investigate the effectiveness of the intervention in terms of transfer benefits on SRL and text analysis skills, 274 lower secondary students were examined in a pretest-training-posttest design. Based on two different training approaches, a distinction was made between four groups: student training (singleST), teacher training (singleTT), combination of student and teacher training (ComT), and control group (CG). Substantially more transfer was revealed in all training conditions as compared to the control group. Specifically, the singleST group showed the highest learning gains for all variables. Conversely, a combination of both approaches (ComT) did not result in synergetic effects, but rather in reciprocal interferences. 1. Introduction In the last few decades, the continuous technological revolution resulted in an efficient processing of information at any time and place as well as in a more flexible learning management. The omnipresent availability and complexity of information, however, necessitate the acquisition of new abilities in order to achieve the level of skills that is necessary to manage the demands of today’s society. For this reason, getting used to the continuous and lifelong need to adapt one’s own behavior and knowledge through self-evident and conscious application of strategies requires starting early with strategy instruction and promotion. Different training programs in all areas of life, whether at preschool [1], primary school [2], secondary school [3], or in the workplace [4], have already shown to be effective in enhancing learning processes and encouraging learners to acquire more self-regulatory learning abilities. Self-regulated learning (SRL) is defined as an “active, constructive process whereby learners (the term “learner” refers to students throughout the document, as the study focuses on an academic setting) set goals for their learning and then attempt to monitor, regulate, and control their cognition, motivation, and behavior, guided and constrained by their goals and the contextual features in the environment” [5]. For the purpose of the present study, we aimed at refining guidelines for a training of self-regulatory skills. The
Embedding Permanent Watermarks in Synthetic Genes
Michael Liss, Daniela Daubert, Kathrin Brunner, Kristina Kliche, Ulrich Hammes, Andreas Leiherer, Ralf Wagner
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0042465
Abstract: As synthetic biology advances, labeling of genes or organisms, like other high-value products, will become important not only to pinpoint their identity, origin, or spread, but also for intellectual property, classification, bio-security or legal reasons. Ideally information should be inseparably interlaced into expressed genes. We describe a method for embedding messages within open reading frames of synthetic genes by adapting steganographic algorithms typically used for watermarking digital media files. Text messages are first translated into a binary string, and then represented in the reading frame by synonymous codon choice. To aim for good expression of the labeled gene in its host as well as retain a high degree of codon assignment flexibility for gene optimization, codon usage tables of the target organism are taken into account. Preferably amino acids with 4 or 6 synonymous codons are used to comprise binary digits. Several different messages were embedded into open reading frames of T7 RNA polymerase, GFP, human EMG1 and HIV gag, variously optimized for bacterial, yeast, mammalian or plant expression, without affecting their protein expression or function. We also introduced Vigenère polyalphabetic substitution to cipher text messages, and developed an identifier as a key to deciphering codon usage ranking stored for a specific organism within a sequence of 35 nucleotides.
Single fraction radiosurgery using Rapid Arc for treatment of intracranial targets
Hendrik A Wolff, Daniela M Wagner, Hans Christiansen, Clemens F Hess, Hilke Vorwerk
Radiation Oncology , 2010, DOI: 10.1186/1748-717x-5-77
Abstract: Ten consecutive patients were treated with Linac-based SRS. Eight patients had one or more brain metastases. The other patients presented a symptomatic vestibularis schwannoma and an atypic meningeoma. For all patients, two plans (CAT/RA) were calculated and analysed.Conformity was higher for RA with additional larger low-dose areas. Furthermore, RA reduced the number of MU and the treatment time for all patients. Dose to organs at risk were equal or slightly higher using RA in comparison to CAT.RA provides a new alternative for single-fraction SRS irradiation combining advantages of short treatment time with lower number of MU and better conformity in addition to accuracy of stereotactic localisation in selected cases with uncomplicated clinical realization.Stereotactic Radiosurgery (SRS) using Conformal Arc Therapy (CAT) is a well established and commonly used irradiation technique for applying high dose to the target while sparing dose to surrounding critical structures via steep dose gradient outside the lesion [1,2]. A very high accuracy of patient positioning and exact online localisation during treatment is required to diminish the safety margin between gross tumour volume (GTV) and planning target volume (PTV). However, there are still some disadvantages like long treatment time, a large number of monitor units (MU), and difficulties in covering of noncircular or ellipsoid targets.In the past, conventional Intensity Modulated Radiotherapy (IMRT) was tested to resolve the difficulties in covering of noncircular or ellipsoid targets with mixed success but without solving all described problems as well in fractionated as in single fraction irradiation procedures [3-7].In the next step, Rapid Arc (RA) - as an advanced development of IMRT - was explored effectually for hypo-fractionated irradiation of brain metastases or benign intracranial diseases [8-10]. The RA technology delivers an entire IMRT treatment in a single gantry rotation around the patient. Three d
Vasculariza??o temporária de membros isquêmicos por meio de shunt arteriomedular: trabalho experimental
Poerschke, Ronaldo André;Silveira, Daniela Augustin;Lodi, Peterson;Titton, Wagner;Marx, Guilherme;Lampert, Alexandre Soares;
Jornal Vascular Brasileiro , 2012, DOI: 10.1590/S1677-54492012000100006
Abstract: background: the authors idealized a temporary shunt between the femoral artery and the medullar canal on long bones to keep the viability of acutely ischemic limbs, while waiting for a definitive treatment. objective: to assess the flow on temporary shunts between the femoral artery and the marrow canal of the tibia during two hours in experimental dogs, which had the femoral artery interrupted. methods: two groups with three dogs on the control group and six on the intervention group were allocated at random. the controls had the right femoral common artery interrupted. the intervention group received a shunt between the iliac external artery and the medullar canal of the right tibia in addition. after two hours, the measure of the ph, blood coloration, blood flow in sonar doppler on the ischemic limbs were performed. the lungs were withdrawn in thoracic block for anatomic-pathologic analyses. results: the capillary blood ph average of the limb extremities in the control group was 6.97 (±0.39) and in the intervention group was 7.25 (±0.46), with p<0.001, and the blood coloration in the intervention group kept the bright aspect in all animals. the shunts needed in average three irrigations with saline heparin solution to be kept unobstructed. the macroscopic and microscopic evaluation of the pulmonary tissue did not evidence fat emboli. conclusion: the artery osseous or artery medullar (marrow) shunt showed to be feasible on the technical point of view in the laboratory.
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