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Search Results: 1 - 10 of 130450 matches for " WEI Hong-Yu "
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Implicit and electrostatic Particle-in-cell/Monte Carlo model in two dimensional and axisymmetric geometry I: analysis of numerical techniques
Hong-yu Wang,Wei Jiang,You-nian Wang
Physics , 2010, DOI: 10.1088/0963-0252/19/4/045023
Abstract: We developed an implicit Particle-in-cell/Monte Carlo model in two-dimensional and axisymmetric geometry for the simulations of the radio-frequency discharges, by introducing several numerical schemes which include variable weights, multigrid field solver, etc. Compared to the standard explicit models, we found that the computational efficiency is significantly increased and the accuracy is still kept. Numerical schemes are discussed and benchmark results are shown. The code can be used to simulate practical reactors.
The PARF Antagonist AChE Inhibitor PMS777 Attenuates LPS-Induced Acute Neuroinflammation  [PDF]
Jin-Jia Hu, Juan Li, Zhang Wei, Hong-Yu Gu, Bi-Yun Shao, Ding Wen Long, Hong-Zhuan Chen
Neuroscience & Medicine (NM) , 2011, DOI: 10.4236/nm.2011.24047
Abstract: When injected into the fourth ventricle, the proinflammagen lipopolysaccharide (LPS) induces acute neuroinflammation in the whole brain of rats. The new compound PMS777 is a novel platelet-activating factor receptor (PAFR) antagonist and acetylcholinesterase (AChE) inhibitor. The current study determined whether PMS777 could provide neuroprotection from the cytotoxic effects associated with LPS-induced neuroinflammation. Acute LPS infusions impaired recognition in rats as measured by the Morris water maze. In addition, LPS infusions decreased the number of AChE positive cells, and increased the number of OX-42 immunoreactive microglia and GFAP immunoreactive astrocytes in the hippocampus, the cortex and the basal nuclei. Furthermore, acute infusions of LPS also impaired organelles associated with protein synthesis. Peripheral administration of PMS777 (i.e., intraperitoneal injection) protected against the impairment in recognition, and attenuated the cytotoxic effects of the acute inflammatory processes upon cholinergic cells, microglia, astrocytes and ultrastructure of hippocampal cells. Here, we propose that the cytotoxic effects of acute neuroinflammation may involve the release of PAF and loss of cholinergic neurons, and this mechanism leads to neuronal dysfunction and spatial memory impairment. The PAFR antagonist inhibitor and AChE inhibitor PMS777 could provide neuroprotection from the cytotoxic effects induced by LPS.
Online upgrading of organic vapors from the fast pyrolysis of biomass
LI Hong-yu,YAN Yong-jie,REN Zheng-wei,
LI Hong-yu
,YAN Yong-jie,REN Zheng-wei

燃料化学学报 , 2008,
Abstract: The online upgrading process that combined the fast pyrolysis of biomass and catalytic cracking of bio-oil was developed to produce a high quality liquid product from the biomass. The installation consisted of a fluidized bed reactor for pyrolysis and a packed bed reactor for upgrading. The proper pyrolysis processing conditions with a temperature of 500℃ and a flow rate of 4m3·h-1 were determined in advance. Under such conditions, the effects of temperature and weight hourly space velocity (WHSV) on both the liquid yields and the oil qualities of the online catalytic cracking process were investigated. The results showed that such a combined process had the superiority of increasing the liquid yield and improving the product quality over the separate processes. Furthermore, when the temperature was 500℃, with a WHSV of 3h-1, the liquid yield reached the maximum and the oxygenic compounds also decreased obviously.
Liver Resection for Hepatocellular Carcinoma in Patients with Cirrhosis: Radiofrequency-Assisted versus Cavitron Ultrasonic Surgical Aspirator
Ke-Fei Chen,Wei-Hong He,Hong-Yu Li,Yong-Gang Wei
Journal of Gastroenterology and Hepatology Research , 2012, DOI: 10.6051/j.issn.2224-3992.2012.01.028
Abstract: AIM: To compare the early postoperative results betweenRadiofrequency (RF)-assisted and Cavitron Ultrasonic SurgicalAspirator (CUSA) liver resection for HCC in patients with cirrhosis.METHODS: 18 cirrhotic patients who underwent RF-assisted liverresection for HCC were compared with 18 cirrhotic patients whounderwent CUSA liver resection. The two groups were well matchedfor age, gender, tumor size, and severity of cirrhosis. (Child-Pugh A).RESULTS: The mean Intraoperative blood loss (RF, 58±61 mL; vsCUSA, 197±75 mL; pr, p=0.001) was statistically less for the RFassistedgroup, The mean hospital stay is shorter in the RF-assistedgroup (RF-assisted, 7±2 days; vs CUSA, 10±3 days; pr, p=0.02).CONCLUSIONS: RF-assisted liver resection for HCC in properlyselected cirrhotic group showed less intraoperative blood loss andshorter hospital stay than the CUSA group.
Zoledronic Acid as an Adjuvant Therapy in Patients with Breast Cancer: A Systematic Review and Meta-Analysis
Wei-Wei Huang, Cheng Huang, Jian Liu, Hong-Yu Zheng, Lin Lin
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0040783
Abstract: Background Zoledronic acid is widely used as adjuvant chemotherapy for the treatment of breast cancer. However, previous trials reported inconsistent findings regarding their clinical efficacy and safety. We carried out a comprehensive systematic review and meta-analysis to evaluate the effects of zoledronic acid on disease-free survival (DFS), overall survival (OS), and drug-related toxicities. Methodology and Principal Findings We systematically searched Medline, EmBase, the Cochrane Central Register of Controlled Trials, reference lists of articles and proceedings of major meetings for relevant literatures with a time limit of Dec. 1, 2011. Randomized controlled trials evaluated the effects of zoledronic acid on OS, DFS, and RFS compared with control were eligible for inclusion in our research. Of 175 identified studies, we collected data from 7 randomized controlled trials of zoledronic acid that had OS, DFS, and RFS reported as one of the endpoint. Overall, we noted that patients receiving zoledronic acid therapy had significant longer OS than the group with non-zoledronic acid therapy (HR, 0.85, 95%CI, 0.73 to 1.00, P = 0.047). Furthermore, zoledronic acid therapy also had a clear effect on frature events (RR, 0.66, 95%CI, 0.52 to 0.84, P<0.001). Subgroup analysis indicated that zoledronic acid therapy showed a great beneficial effect on disease recurrence in patients with early-stage breast cancer, however, it also significantly increased the harm of disease recurrence in patients with advanced breast cancer. Bone pain, neutropenic fever, pyrexia, rash were more frequent in the zoledronic acid therapy group. Conclusion/Significance Treatment with zoledronic acid had a clear effect on fracture events, and it might contribute an important role for overall survival.
Effects on Strengths of Cement Mortar When Using Incinerator Bottom Ash as Fine Aggregate  [PDF]
Min-Jen Yang, Hong-Yu Wang, Hong-Yu Wang
World Journal of Engineering and Technology (WJET) , 2014, DOI: 10.4236/wjet.2014.23B007
Abstract:

The main purpose of this paper is to study the feasibility of using the Incinerator bottom ash fine aggregate to replace natural fine aggregate in the cement mortar products. The research adopts high cement content mortar to conduct the experiment, in which the weight ratio of cement/aggregate is 1/2. The experiment uses Incinerator bottom ash fine aggregates, which passes through #16 sieve, and natural sand of the same size as the aggregate, and separates mortar specimens in- to two main categories based on different W/C ratio. Moreover, different proportions of furnace slag and F-class are used to replace a portion of cement so as to explore the influence on strength of Incinerator bottom ash aggregates mortar by adding the two admixtures. The study shows that, based on the 1:2 cement/aggregate weight ratio, Incinerator bottom ash fine aggregates mortar, unit weight around 1.8 g/cm3, is 20% lighter natural fine aggregate mortar, unit weight around 2.2 g/cm3. The Incinerator bottom ash fine aggregates mortar can only reach 60%-70% the compressive strength of natural fine aggregates mortar. Direct tensile strength and flexural tensile strength tests are 15% and 30% of compressive strength respectively, due to the irregular strength development, which does not follow general concepts, such as low W/C ratio and mineral admixtures will not necessarily help in strength development in Incinerator bottom ash fine aggregates mortar.

A Gene's Ability to Buffer Variation Is Predicted by Its Fitness Contribution and Genetic Interactions
Guang-Zhong Wang,Jian Liu,Wei Wang,Hong-Yu Zhang,Martin J. Lercher
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0017650
Abstract: Many single-gene knockouts result in increased phenotypic (e.g., morphological) variability among the mutant's offspring. This has been interpreted as an intrinsic ability of genes to buffer genetic and environmental variation. A phenotypic capacitor is a gene that appears to mask phenotypic variation: when knocked out, the offspring shows more variability than the wild type. Theory predicts that this phenotypic potential should be correlated with a gene's knockout fitness and its number of negative genetic interactions. Based on experimentally measured phenotypic capacity, it was suggested that knockout fitness was unimportant, but that phenotypic capacitors tend to be hubs in genetic and physical interaction networks.
Isolation and Characterization of an Antibacterial Peptide Fraction from the Pepsin Hydrolysate of Half-Fin Anchovy (Setipinna taty)
Ru Song,Rong-Bian Wei,Hong-Yu Luo,Dong-Feng Wang
Molecules , 2012, DOI: 10.3390/molecules17032980
Abstract: Enzymatic proteolysis of food proteins is considered a promising method to generate antibacterial peptides. The objective of the present study was to isolate and characterize peptide fraction from the pepsin hydrolysate of half-fin anchovy (Setipinna taty) with antibacterial activity against Escherichia coli. The most active peptide fraction HAHp2-3-I was isolated by a series of chromatographic methods, including Sephadex G-25 chromatography, reverse high-performance liquid chromatography (RP-HPLC) and Source 5RPC ST. Peptides identification of HAHp2-3-I was carried out using UPLC-LTQ-Orbitrap mass spectrometer. HAHp2-3-I contained five cationic peptides (MLTTPPHAKYVLQW, SHAATKAPPKNGNY, PTAGVANALQHA, QLGTHSAQPVPF and VNVDERWRKL) and three anionic peptides (LATVSVGAVELCY, NPEFLASGDHLDNLQ and PEVVYECLHW). Prediction of peptide secondary structure indicated that these anionic peptides should have extended strand and random coil structures, whereas cationic peptides PTAGVANALQHA and VNVDERWRKL could form alpha helixes. In addition, results of scanning electron microscopy (SEM) revealed that treatment by HAHp2-3-I could cause the morphological changes of E. coli and destruction of the cell integrity via irreversible membrane damage. The results could provide information for investigating the antibacterial model of antibacterial peptides derived from fish protein hydrolysates.
Magnetization of mixed ferri-ferrimagnets composed of Prussian blue analogs A1xA21-xB

Jiang Wei,Guan Hong-Yu,Lo Veng-Cheong,

中国物理 B , 2011,
Abstract: The magnetization of ternary metal Prussian blue analogues A1xA21-xB, formed by three different sublattices A1, A2 and B, is studied by using the effective-field theory with self-spin correlations. Effects of the mole fraction x, the anisotropy and the transverse magnetic field on the magnetization are discussed.
Effects of anisotropy on quantum fluctuation of a three-layer system with mutisublattice

Jiang Wei,Zhang Fan,Guan Hong-Yu,Liang Ji-Yan,

中国物理 B , 2010,
Abstract: The quantum fluctuations of a three-layer Heisenberg model with six sublattices are studied by the retarded Green's function method and the spin-wave theory. The effects of anisotropy on the quantum fluctuations at zero temperature are discussed. The results show that the interlayer anisotropy plays an important role in balancing the quantum competitions.
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