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Search Results: 1 - 10 of 134361 matches for " WANG Ying-ying "
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Tetraaqua{1-[(1H-1,2,3-benzotriazol-1-yl)methyl]-1H-imidazole}sulfatomanganese(II) dihydrate
Ying Wang,Ying-Ying Sun
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811022197
Abstract: In the title complex, [Mn(SO4)(C10H9N5)(H2O)4]·2H2O, the Mn2+ cation is six-coordinated by one N atom from a 1-[(1H-1,2,3-benzotriazol-1-yl)methyl]-1H-imidazole ligand and five O atoms from one monodentate sulfate ligand and four water molecules in a distorted octahedral geometry. In the crystal, adjacent molecules are linked through O—H...O and O—H...N hydrogen bonds into a three-dimensional network.
Bis[N-(1-naphthyl)ethylenediammonium] hexabromidoplumbate(II)
Yao Chen,Ying-Ying Zheng,Gang Wu,Mang Wang
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810008901
Abstract: The title compound, (C12H16N2)2[PbBr6], is an organic–inorganic salt, with two doubly protonated N-(1-naphthyl)ethylenediammonium cations and one octahedral hexabromidoplumbate(II) anion. The PbII atom is located on a centre of inversion. The crystal structure consists of alternating inorganic and organic layers parallel to the bc plane. Face-to-face aromatic stacking interactions [centroid–centroid distance = 3.505 (5) ] occur between parallel naphthalene systems in the organic layers, and N—H...Br hydrogen bonds between the cations and anions stabilize the crystal structure.
Poly[[μ2-2,2′-diethyl-1,1′-(butane-1,4-diyl)diimidazole-κ2N3:N3′](μ2-5-hydroxyisophthalato-κ2O1:O3)zinc]
Ying-Ying Liu,Xing Wang,Yong-Sheng Yan
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811039377
Abstract: In the title coordination polymer, [Zn(C8H4O5)(C14H22N4)]n, the ZnII cation is coordinated by an O2N2 donor set in a distorted tetrahedral geometry. The ZnII ions are linked by μ2-OH-bdc (OH-H2bdc = 5-hydroxyisophthalic acid) and bbie ligands [bbie = 2,2′-diethyl-1,1′-(butane-1,4-diyl)diimidazole], forming a two-dimensional layer parallel to the ab plane. The layers are further connected through intermolecular C—H...O and O—H...O hydrogen bonds, forming a three-dimensional supramolecular structure. In the bbie ligand, the two C atoms in the ethyl group are each disordered over two positions with a site-occupancy ratio of 0.69:0.31.
Ethyl 1-(2-bromoethyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxylate
Ling Yin,Yi Wang,Ying-Ying Wang,Jian-Wu Wang
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812032370
Abstract: In the title compound, C15H17BrN2O3, the dihedral angle between the benzene and pyrazole rings is 5.63 (2)°. The crystal packing is stabilized by weak π–π stacking interactions [centroid–centroid distance = 3.927 (5) ] and intermolecular C—H...O and C—H...Br hydrogen bonds.
An Explicit Scheme for the KdV Equation

WANG Hui-Ping,WANG Yu-Shun,HU Ying-Ying,

中国物理快报 , 2008,
Abstract: A new explicit scheme for the Korteweg--de Vries (KdV) equation is proposed. The scheme is more stable than the Zabusky--Kruskal scheme and the multi-symplectic six-point scheme. When used to simulate the collisions of multi-soliton, it does not show the nonlinear instabilities and un-physical oscillations.
Altering Mucus Rheology to “Solidify” Human Mucus at the Nanoscale
Samuel K. Lai, Ying-Ying Wang, Richard Cone, Denis Wirtz, Justin Hanes
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0004294
Abstract: The ability of mucus to function as a protective barrier at mucosal surfaces rests on its viscous and elastic properties, which are not well understood at length scales relevant to pathogens and ultrafine environmental particles. Here we report that fresh, undiluted human cervicovaginal mucus (CVM) transitions from an impermeable elastic barrier to non-adhesive objects sized 1 μm and larger to a highly permeable viscoelastic liquid to non-adhesive objects smaller than 500 nm in diameter. Addition of a nonionic detergent, present in vaginal gels, lubricants and condoms, caused CVM to behave as an impermeable elastic barrier to 200 and 500 nm particles, suggesting that the dissociation of hydrophobically-bundled mucin fibers created a finer elastic mucin mesh. Surprisingly, the macroscopic viscoelasticity, which is critical to proper mucus function, was unchanged. These findings provide important insight into the nanoscale structural and barrier properties of mucus, and how the penetration of foreign particles across mucus might be inhibited.
Mucoadhesive Nanoparticles May Disrupt the Protective Human Mucus Barrier by Altering Its Microstructure
Ying-Ying Wang,Samuel K. Lai,Conan So,Craig Schneider,Richard Cone,Justin Hanes
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0021547
Abstract: Mucus secretions typically protect exposed surfaces of the eyes and respiratory, gastrointestinal and female reproductive tracts from foreign entities, including pathogens and environmental ultrafine particles. We hypothesized that excess exposure to some foreign particles, however, may cause disruption of the mucus barrier. Many synthetic nanoparticles are likely to be mucoadhesive due to hydrophobic, electrostatic or hydrogen bonding interactions. We therefore sought to determine whether mucoadhesive particles (MAP) could alter the mucus microstructure, thereby allowing other foreign particles to more easily penetrate mucus. We engineered muco-inert probe particles 1 μm in diameter, whose diffusion in mucus is limited only by steric obstruction from the mucus mesh, and used them to measure possible MAP-induced changes to the microstructure of fresh human cervicovaginal mucus. We found that a 0.24% w/v concentration of 200 nm MAP in mucus induced a ~10-fold increase in the average effective diffusivity of the probe particles, and a 2- to 3-fold increase in the fraction capable of penetrating physiologically thick mucus layers. The same concentration of muco-inert particles, and a low concentration (0.0006% w/v) of MAP, had no detectable effect on probe particle penetration rates. Using an obstruction-scaling model, we determined that the higher MAP dose increased the average mesh spacing (“pore” size) of mucus from 380 nm to 470 nm. The bulk viscoelasticity of mucus was unaffected by MAP exposure, suggesting MAP may not directly impair mucus clearance or its function as a lubricant, both of which depend critically on the bulk rheological properties of mucus. Our findings suggest mucoadhesive nanoparticles can substantially alter the microstructure of mucus, highlighting the potential of mucoadhesive environmental or engineered nanoparticles to disrupt mucus barriers and cause greater exposure to foreign particles, including pathogens and other potentially toxic nanomaterials.
An analysis of Cyclin D1, Cytokeratin 5/6 and Cytokeratin 8/18 expression in breast papillomas and papillary carcinomas
Yu Wang, Jin-fu Zhu, Ying-ying Liu, Gui-ping Han
Diagnostic Pathology , 2013, DOI: 10.1186/1746-1596-8-8
Abstract: Fifty-nine cases of papillary lesions including 36 papillomas and 23 intracystic papillary carcinomas were examined. Cyclin D1, CK 5/6 and CK 8/18 expression levels were evaluated by double immunostaining.Cyclin D1 is highly expressed in papillary carcinomas (27.54%?±?15.43%) compared with papillomas (8.81%?±?8.41%, p?<?0.01). Cyclin D1 is predominantly expressed in Cytokeratin 8/18- expressing cells, rather than in Cytokeratin 5/6-expressing cells, regardless of the type of lesion. In Papillomas, Cyclin D1 exhibited a mean 11.42% (11.42%?±?10.17%) co-expression rate with Cytokeratin 8/18 compared with a mean 2.50% (2.50%?±?3.24%) co-expression rate with Cytokeratin 5/6 (p?<?0.01). In papillary carcinomas, Cyclin D1 exhibited a mean 34.74% (34.74%?±?16.32%) co-expression rate with Cytokeratin 8/18 compared with a co-expression rate of 0.70% (0.70%?±?0.93%) with Cytokeratin 5/6 (p?<?0.01).The increase in Cyclin D1 suggests an association of Cyclin D1 staining with papillary carcinomas. Although Cyclin D1 is an effective marker for the differential diagnosis of other papillary lesions, it cannot be used to distinguish between papilloma and papillary carcinoma lesions because its expression occurs in both lesions. Our results show that Cyclin D1 and CK 5/6 staining could be used in concert to distinguish between the diagnosis of papilloma (Cyclin D1?<?4.20%, CK 5/6 positive) or papillary carcinoma (Cyclin D1?>?37.00%, CK 5/6 negative). In addition, our data suggest that Cyclin D1 is expressed only in the cancer stem or progenitor cells that co-immunostained with CK 8/18 in papillary carcinomas, and predominantly with CK 8/18 in the papillomas.The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/7299340558756848 webcitePapillary breast tumors consist of proliferative mammary epithelial cells that invade the ductal lumen and form fibro-vascular stalks that may evolve into branching arborescent structures. Intraductal papi
AUTOMATIC PHASE CORRECTION FOR NMR SPECTRA-CONNECTING LINE OF EQUALLY SPACED POINTS(CLESP)
核磁共振谱图自动相位校正新方法——等密度点连线法

WANG Chao,HUANG Ying-ying,YANG Guang~,
王超
,黄颖颖,杨光

波谱学杂志 , 2004,
Abstract: A novel automatic phase correction method, CLESP, for NMR spectra based on DISPA circle is described in this paper. The phase angles of peaks are determined from the slope of the line connecting two peak points with equal data point density on each side of the peak on the complex plane. The calculated phase angles of the peaks are then used to extract the zero-order and first-order phase correction for the full spectrum by linear regression. In addition to the advantages of being non-iterative, fast, accurate, straightforward, easy to implement, and applicable to partial peaks, CLESP is robust with respect to noise, baseline distortion, peak overlaps, and poor digitization of NMR signals. CLESP algorithm has been successfully implemented in ECNMR , a home-made NMR data-processing software.
Antialgal mechanism of growth-inhibitor isolated from marine micoralga of Isochrysis galbana
利球等鞭金藻生长抑制物的抑藻机理

SUN Ying-ying,WANG Chang-hai,
孙颖颖
,王长海

浙江大学学报(农业与生命科学版) , 2009,
Abstract: 通过球等鞭金藻生长抑制物(1-羟基,丙二酸二乙酯-十二烯酸异丙酯)对6种海洋微藻(牟氏角毛藻、纤细角毛藻、三角褐指藻、新月菱形藻、扁藻和盐藻)的生长及细胞内主要生化成分的影响,对该抑藻物质的抑藻机理进行探讨.结果表明,该生长抑制物对6种微藻生长不仅具有明显的抑制作用,而且对微藻细胞内的一些主要生化成分有显著的影响.在该抑制物作用下,6种微藻细胞内的叶绿素含量显著降低,丙二醛含量以及胞外可溶性蛋白质和多糖含量明显提高,硝酸还原酶、过氧化物酶和超氧化物歧化酶的活性也有不同程度的升高或降低.可见,球等鞭金藻生长抑制物是通过对微藻细胞内的某些主要生化成分的合成过程及其活性的调控,实现对微藻藻细胞的生长控制.
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