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Search Results: 1 - 10 of 129031 matches for " WANG Hao "
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Using schema transforation pathways for biological data integration  [PDF]
Hao Fan, Fei Wang
Journal of Biomedical Science and Engineering (JBiSE) , 2008, DOI: 10.4236/jbise.2008.13035
Abstract: In web environments, proteomics data integra-tionin the life sciences needs to handle the problem of data conflicts arising from the het-erogeneity of data resources and from incom-patibilities between the inputs and outputs of services used in the analysis of the resources. The integration of complex, fast changing bio-logical data repositories can be potentially sup-ported by Grid computing to enable distributed data analysis. This paper presents an approach addressing the data conflict problems of pro-teomics data integration. We describe a pro-posed proteomics data integration architecture, in which a heterogeneous data integration sys-tem interoperates with Web Services and query processing tools for the virtual and materialised integration of a number of proteomics resources, either locally or remotely. Finally, we discuss how the architecture can be further used for supporting data maintenance and analysis ac-tivities.
Effects of Chinese herbal medicine Jinqi Jiangtang Tablet on serum matrix metalloproteinase-9 level and its expression in peripheral blood monocytes of rats with diabetes mellitus
Hao Wang
Zhong Xi Yi Jie He Xue Bao , 2011,
Abstract: Objective: To observe the effects of Jinqi Jiangtang Tablet, a compound Chinese herbal medicine, on serum matrix metalloproteinase-9 (MMP-9) level and MMP-9 expression in peripheral blood monocytes of rats with streptozocin-induced diabetes. Methods: Thirty Wistar rats were randomly divided into 3 groups: control group, untreated group and Jinqi Jiangtang Tablet group. Diabetes in rats was induced by a single intraperitoneal injection of streptozocin (70 mg/kg body weight). After model building, rats in the Jinqi Jiangtang Tablet group were administered with Jinqi Jiangtang tablets at a dose of 0.8 g/(kg·d) for 6 weeks and rats in the control group and the untreated group were treated with normal saline. After treatment, level of fasting serum glucose was detected by hexokinas method; serum MMP-9 level was tested by enzyme-linked immunosorbent assay; MMP-9 expression in peripheral blood monocytes was measured by reverse transcription-polymerase chain reaction and Western blot method. Results: After treatment, fasting serum glucose level in the Jinqi Jiangtang Tablet group was less than that in the untreated group (P<0.05). After modeling, the serum MMP-9 level of rats in the untreated group was (9.11±3.55) μg/L and that in Jinqi Jiangtang Tablet group was (8.97±3.07) μg/L, which were higher than that in the control group ((4.39±1.44) μg/L) (P<0.01). After gavage, the level of serum MMP-9 was lower in Jinqi Jiangtang Tablet group than in the untreated group (P<0.05). The expression of MMP-9 in peripheral blood monocytes in the untreated group was higher than that in the control group (P<0.05). The MMP-9 expression in peripheral blood monocytes of rats with diabetes was down-regulated by Jinqi Jiangtang Tablet (P<0.05). Conclusion: Jinqi Jiangtang Tablet can decrease the level of serum MMP-9 and down-regulate the MMP-9 expression in peripheral blood monocytes at both mRNA and protein levels in rats with diabetes.
A Posteriori Error Estimates for Energy-Based Quasicontinuum Approximations of a Periodic Chain
Hao Wang
Mathematics , 2011,
Abstract: We present a posteriori error estimates for a recently developed atomistic/continuum coupling method, the Consistent Energy-Based QC Coupling method. The error estimate of the deformation gradient combines a residual estimate and an a posteriori stability analysis. The residual is decomposed into the residual due to the approximation of the stored energy and that due to the approximation of the external force, and are bounded in negative Sobolev norms. In addition, the error estimate of the total energy using the error estimate of the deformation gradient is also presented. Finally, numerical experiments are provided to illustrate our analysis.
Two New Algorithms for Solving Covariance Graphical Lasso Based on Coordinate Descent and ECM
Hao Wang
Statistics , 2012,
Abstract: Covariance graphical lasso applies a lasso penalty on the elements of the covariance matrix. This method is useful because it not only produces sparse estimation of covariance matrix but also discovers marginal independence structures by generating zeros in the covariance matrix. We propose and explore two new algorithms for solving the covariance graphical lasso problem. Our new algorithms are based on coordinate descent and ECM. We show that these two algorithms are more attractive than the only existing competing algorithm of Bien and Tibshirani (2011) in terms of simplicity, speed and stability. We also discuss convergence properties of our algorithms.
Scaling It Up: Stochastic Search Structure Learning in Graphical Models
Hao Wang
Statistics , 2015, DOI: 10.1214/14-BA916
Abstract: Gaussian concentration graph models and covariance graph models are two classes of graphical models that are useful for uncovering latent dependence structures among multivariate variables. In the Bayesian literature, graphs are often determined through the use of priors over the space of positive definite matrices with fixed zeros, but these methods present daunting computational burdens in large problems. Motivated by the superior computational efficiency of continuous shrinkage priors for regression analysis, we propose a new framework for structure learning that is based on continuous spike and slab priors and uses latent variables to identify graphs. We discuss model specification, computation, and inference for both concentration and covariance graph models. The new approach produces reliable estimates of graphs and efficiently handles problems with hundreds of variables.
GF-5 VIMI On-Orbit Calibration Instrument and Performance  [PDF]
Hao Wang
Journal of Computer and Communications (JCC) , 2019, DOI: 10.4236/jcc.2019.77024
Abstract:
The Visible and Infrared Multispectral Imager (VIMI) is one of the main payloads of the GF-5 satellite. It has 12 spectral bands covering the wavelength from visible light to thermal infrared. The imager designed life is 8 years. In order to monitor and correct the radiometric performance of the imager for a long time and meet the user’s demand for the quantitative remote sensing application, the expandable diffuser used for calibration in full FOV and full optical path method is designed. The solar diffuser is installed on the front side of the optical system and does not affect the normal imaging of VIMI. When VIMI need calibration, the diffuser is expand to the front of optical system via the driving mechanism. According to the characteristics of the GF-5 satellite orbit, the requirement of the calibration energy and the installation matrix of the imager relative to the satellite, the expansion angle of the diffuser is 39 degrees. The 430 mm × 430 mm large-size PTEE diffuser is manufactured to ensure full FOV and full optical path calibration. The diffuser’s directional hemispherical reflectance is higher than 95% from 420 nm to 2400 nm and variation of BRDF in the direction of imager observation is better than 2.5%. The diffuser stability monitoring radiometer is designed to monitor the on-orbit attenuation performance of the diffuser. Results of ground simulation experiments and preliminary on-board calibration experiments were introduced.
Plasmonic Light Trapping in an Ultrathin Photovoltaic Layer with Film-Coupled Metamaterial Structures
Hao Wang,Liping Wang
Physics , 2014,
Abstract: A film-coupled metamaterial structure is numerically investigated for enhancing the light absorption in an ultrathin photovoltaic layer of crystalline gallium arsenide (GaAs). The top subwavelength concave grating and the bottom metallic film could not only effectively trap light with the help of wave interference and magnetic resonance effects excited above the bandgap, but also practically serve as electrical contacts for photon-generated charge collection. The energy absorbed by the active layer is greatly enhanced in the film-coupled metamaterial structure, resulting in significant enhancement on the short-circuit current density by three times over a free-standing GaAs layer at the same thickness. The results would facilitate the development of next-generation ultrathin solar cells with lower cost and higher efficiency.
Tailoring Thermal Radiative Properties with Film-Coupled Concave Grating Metamaterials
Hao Wang,Liping Wang
Physics , 2014, DOI: 10.1016/j.jqsrt.2014.11.015
Abstract: This work numerically investigates the radiative properties of film-coupled metamaterials made of a two-dimensional metallic concave grating on a continuous metal film separated by an ultrathin dielectric spacer. Spectrally-selective absorption is demonstrated in the visible and near-infrared regime, and underlying mechanisms are elucidated to be either localized magnetic polaritons (MPs) or surface plasmon polaritons (SPPs). The unique behaviors of MPs and SPPs are explained with the help of electromagnetic field distributions at respective resonance frequencies. An inductor-capacitor model is utilized to further confirm the excitation of MP, while dispersion relation is used to understand the behaviors of different SPP modes. Geometric effects of ridge width and grating period on the resonance absorption peaks are discussed. Moreover, directional responses at oblique incidences for different polarization states are studied. Fundamental understanding gained here will facilitate the design of novel metamaterials in energy harvesting and sensing applications.
Analysis of the Spectral Resolution of a TeO2 based Noncollinear Acousto-Optic Tunable Filter  [PDF]
Chunguang Zhang, Hao Wang, Yishen Qiu
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.33027
Abstract: The spectral resolution is a main index of evaluating the performance of the designed acousto-optic tunable filter (AOTF). In this letter, an accurate expression of the spectral resolution is presented by considering both the birefringence and the rotatory property of TeO2 crystal. The deduced expression is significant in improving the accuracy of the design of an AOTF and pushing the development of the high-performance AOTF.
Study of Ni/Al Interface Diffusion by Molecular Dynamics Simulation  [PDF]
Chunguang Zhang, Hao Wang, Yishen Qiu
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.33026
Abstract: Molecular dynamics simulation of Ni/Al interface diffusion is carried out by Embedded Atom Method (EAM) potential. The problem how the temperature affects Ni/Al interface diffusion is discussed. The initial dynamic behavior of Ni/Al interface diffusion at high temperature is shown. The study in this letter is helpful to understand the origin of diffusion phenomenon.
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