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Search Results: 1 - 10 of 6229 matches for " Vincent Boitier "
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The Unemployment Volatility Puzzle: A Note on the Role of Reference Points  [PDF]
Vincent Boitier
Theoretical Economics Letters (TEL) , 2015, DOI: 10.4236/tel.2015.51013
Abstract: This theoretical note aims at studying the role of reference points in generating unemployment volatility. For this purpose, I introduce the notion of reference points in a standard Mortensen-Pissarides model. I obtain two results. First, I find that the obtained model is similar to the one found by Pissarides in 2009. Second, I show that the introduction of reference points can increase significantly unemployment volatility through a mechanism à la Hagerdorn and Manovskii.
Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease
Eric Boitier, Jean-Charles Gautier, Ruth Roberts
Comparative Hepatology , 2003, DOI: 10.1186/1476-5926-2-3
Abstract: The evaluation of the safety of drugs is a vital but complex process. Normally, candidate drugs are tested in a range of in vivo and in vitro pre-clinical models that serve to evaluate genotoxicity, general toxicity, reproductive toxicology and cardiovascular safety. In vivo studies use both rodent and non-rodent animal dosing models depending on the endpoint and the compound characteristics. Although such models provide useful information, for some classes of compounds, the rodent models are poor predictors of human response, in some cases due to marked species differences in expression of the target receptors. For example, the family of peroxisome proliferator activated receptors (PPARs) display differences in expression and activation profiles between rodents and humans making the rodent models poor predictors of human response. However, this receptor family is an excellent drug target since the different isotypes PPARα, PPARβ and PPARγ play a central role in coordinating energy balance. Thus, PPARα ligands are hypolipidaemic and PPARγ ligands are insulin sensitizers with efficacy in type II diabetes. Here, we consider the response to PPAR ligands seen in pre-clinical models of efficacy and safety in the context of human health and disease.PPARs are ligand-inducible transcription factors that belong to the nuclear hormone receptor superfamily, together with the receptors for thyroid hormone, retinoids, steroid hormones and vitamin D. According to the recently proposed nomenclature of nuclear hormone receptors [1,2], PPARs form the group C in the subfamily 1 of the superfamily of nuclear hormone receptors, i.e., NR1C. PPARs occur in three different isotypes, namely PPARα (NR1C1), PPARβ (also called PPARδ, NUC-1 or FAAR), and PPARγ (NR1C3). These receptors have been found in various species such as cyclostoma [3], teleosts [3], amphibians [3], rodents [4] and humans [5-7]. There are three isoforms of PPARγ [8]; PPARγ1 and PPARγ3 are identical when fully translated
Jean-Louis Chermant,Guillaume Boitier,Severine Darzens,Michel Coster
Image Analysis and Stereology , 2001, DOI: 10.5566/ias.v20.p207-211
Abstract: This paper shows how it is possible to characterize and quantify the damages in materials using classical tools of automatic image analysis. Examples presented concern ceramic matrix composites, i.e. high tech materials. It gives important information to support the deformation and rupture mechanism of materials under mechanical solicitations.
Eigenvector Sensitivity: A Kharitonov Result  [PDF]
Vincent Winstead
American Journal of Computational Mathematics (AJCM) , 2013, DOI: 10.4236/ajcm.2013.32024

This study is motivated by a need to effectively determine the difference between a system fault and normal system operation under parametric uncertainty using eigenstructure analysis. This involves computational robustness of eigenvectors in linear state space systems dependent upon uncertain parameters. The work involves the development of practical algorithms which provide for computable robustness measures on the achievable set of eigenvectors associated with certain state space matrix constructions. To make connections to a class of systems for which eigenvalue and characteristic root robustness are well understood, the work begins by focusing on companion form matrices associated with a polynomial whose coefficients lie in specified intervals. The work uses an extension of the well known theories of Kharitonov that provides computational efficient tests for containment of the roots of the polynomial (and eigenvalues of the companion matrices) in desirable regions, such as the left half of the complex plane.

Dealing with Complex Management Problems  [PDF]
Vincent Omachonu
Open Journal of Business and Management (OJBM) , 2014, DOI: 10.4236/ojbm.2014.21002
Abstract: Dealing with Complex Management Problems
Review Article: Remote Sensing, Surface Residue Cover and Tillage Practice  [PDF]
Obade Vincent de Paul
Journal of Environmental Protection (JEP) , 2012, DOI: 10.4236/jep.2012.32026
Abstract: A growing world population and possible liquid fuel energy shortages are likely to result in worldwide agricultural intensification, and the possible expansion of non-sustainable practices. The adoption of non-sustainable practices could result in the loss of currently productive land, with potential impacts on human welfare and economic viability. One of the easiest techniques to maintain productivity is to maintain surface soil organic matter. However, developing reliable, cost effective and accurate methods for quantifying and monitoring crop residue cover (a major source of soil organic matter) that remains on top of the soil over large spatial extents constitutes a significant challenge. This article reviews potential remote sensing approaches for estimating surface residue cover with a view to mapping tillage practice.
Managerial Skills, Financial Capability and Strategic Planning in Organizations  [PDF]
Vincent Bagire, Juliana Namada
American Journal of Industrial and Business Management (AJIBM) , 2013, DOI: 10.4236/ajibm.2013.35055

This study sought to establish the relationship between managerial skills, financial capability and the level of strategic planning. The study was premised on the increasing focus on strategic planning in Ugandan organizations. There was however, a lack of local empirical studies on the factors driving this trend. Data were obtained from organizations in various sectors that included government institutions, private and family business organizations. The findings confirmed that organizations were involved in significant level of strategic planning. There was a positive and significant relationship with managerial skills. However, there was a very weak relationship with the financial capability. The implication of the findings for management was to give more attention to managerial skills to ensure congruence of operations.

An Integrative Framework for Customizations on Satisfaction: The Case of an Online Jewelry Business in China  [PDF]
Vincent Cho, Candy Lau
Journal of Service Science and Management (JSSM) , 2014, DOI: 10.4236/jssm.2014.72013

Upon the technological advancement of production flexibility, supply chain agility, and customer behavioral tracking, many online businesses now develop their customization strategies. In this regard, this study proposes an integrative framework for customization of product information, transaction handling, product attribute, and sales’ service. We are interested in how these customizations affect customer satisfaction. From our web-based survey on a renowned online jewelry company in China, we collected 1383 responses from its customer database. Our findings showed that information, product and sales’ service customizations have significant influence on customer satisfaction. Moreover, ordinary members as compared with VIP members feel more satisfied once they receive customized services.

Minkowski Sum of Polytopes Defined by Their Vertices  [PDF]
Vincent Delos, Denis Teissandier
Journal of Applied Mathematics and Physics (JAMP) , 2015, DOI: 10.4236/jamp.2015.31008

Minkowski sums are of theoretical interest and have applications in fields related to industrial backgrounds. In this paper we focus on the specific case of summing polytopes as we want to solve the tolerance analysis problem described in [1]. Our approach is based on the use of linear programming and is solvable in polynomial time. The algorithm we developed can be implemented and parallelized in a very easy way.

Interest Rate Volatility: A Consol Rate Approach  [PDF]
Vincent Brousseau, Alain Durré
Journal of Mathematical Finance (JMF) , 2015, DOI: 10.4236/jmf.2015.51006
Abstract: In this paper, we propose a new methodology to estimate the volatility of interest rates in the euro area money market. In particular, our approach aims at avoiding the limitations of market implied volatilities, i.e. the dependency on arbitrary choices in terms of maturity and frequencies and/or of other factors like credit and liquidity risks. The measure is constructed as the implied instantaneous volatility of a consol bond that would be priced on the EONIA swap curve over the sample period from 4 January 1999 to 21 November 2013. Our findings show that this measure tracks well the historical volatility since, by dividing the consol excess returns by our volatility measure. This removes nearly entirely excess of kurtosis and volatility clustering, bringing the excess returns close to an ordinary Gaussian white noise.
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