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Diversidade humana, rela es sociais de gênero e luta de classes: emancipa o para além da cultura
Marlise Vinagre Silva
Em Pauta : Teoria Social e Realidade Contemporanea , 2012,
Abstract: Este artigo analisa de forma crítica o uso de abordagens culturalistas sobre diversidade de gênero e diversidade sexual, apontando seu limite, tendo em vista a defesa da constru o de uma nova ordem social que supere o ca-pitalismo. Defende a articula o do debate sobre a diversidade como elemento constitutivo da singularidade/originalidade dos sujeitos reais e da uni-versalidade do gênero humano, a partir da defesa da perspectiva marxista de totalidade. Finalmente, prop e a unidade estratégica das lutas específicas em torno da diversidade de gênero e da diversidade sexual com as lutas de classe, na dire o da emancipa o humana.
Practical application of digital fractional-order controller to temperature control
Petrá? Ivo,Vinagre Blas M.
Acta Montanistica Slovaca , 2002,
Abstract: Príspevok sa zaoberá praktickym návrhom a aplikáciou èíslicového regulátora neceloèíselného rádu na riadenie teploty iarièa. V príspevku je alej uvedeny matematicky popis regulátorov a regulovanych sústav neceloèíselného rádu. Pre pou itie èíslicovych regulátorov neceloèíselného rádu je uvedeny príslu ny algoritmus. Vlastnosti regulaèného obvodu s regulátorom neceloèíselného rádu sú porovnané s regulaènym obvodom s klasickym regulátorom celoèíselného rádu a dosiahnuté vysledky sú uvedené a diskutované v závere príspevku.
Ajuda entre passageiros de ?nibus
Silva, Abelardo Vinagre da;Günther, Hartmut;
Estudos de Psicologia (Natal) , 2001, DOI: 10.1590/S1413-294X2001000100008
Abstract: helping behavior among passengers can contribute to the quality of mass transit. during forty bus trips, circumstances under which seated passengers would help those standing were registered by way of systematic observations. the criterion behavior was offering to hold baggage for a standing passenger. overall, in 60 percent of the situations help was offered. significantly more help was offered in a bus line going to a working class suburb than in a center city line. women were more likely to offer help, as were passengers in a situation of eye to eye contact. the data suggest that helping behavior favoring better quality of mass transit may be found. the placing of educational signs inside the bus or at the bus station may further stimulate helping and other pro-social behaviors.
Effect of baclofen on liquid and solid gastric emptying in rats
Collares, Edgard Ferro;Vinagre, Adriana Mendes;
Arquivos de Gastroenterologia , 2010, DOI: 10.1590/S0004-28032010000300015
Abstract: context: gamma-aminobutyric acid (gaba) is a potent inhibitory neurotransmitter. there is evidence that gabab receptors located in the dorsal complex and in afferent fibers of the vagus nerve participate in the control of gastrointestinal motility. objective: to assess the intracerebroventricularly (icv) and intravenously (iv) effect of baclofen, a gabab receptor agonist, on liquid and solid gastric emptying in rats. methods: adult male wistar rats weighing 250-300 g (n = 6-8 animals) were used. gastric emptying of liquid test meals labeled with phenol red was evaluated by the determination of percent gastric retention (%gr) 10 and 15 min after orogastric administration of saline and 10% glucose meals, respectively. baclofen was injected icv (1 and 2 μg/animal) through a tube implanted into the lateral ventricle of the brain and was injected iv (1 and 2 mg/kg) into a tail vein. the gastric emptying of liquid was determined 10 or 30 min after icv and iv baclofen administration, respectively. the gastric emptying of the solid meal was assessed by the determination of percent gastric retention 2 h after the beginning of the ingestion of the habitual ratio by the animal, consumed over a period of 30 min. baclofen was administered icv (1 and 2 μg/animal) or iv (1 and 2 mg/kg) immediately after the end of the ingestion of the solid meal. the control groups received vehicle (sterile saline solution) icv or iv. results: the group of animals receiving baclofen icv (2 mg/animal) presented a significantly lower (p<0.05, tukey test) %gr (mean ± sem) of the saline (18.1 ± 2.5%) compared to control (33.2 ± 2.2%). in the group receiving the drug iv, the gastric retention of the same test meal did not differ from control. icv and iv administration of baclofen had no effect on the gastric emptying of the 10% glucose solution compared to control. icv administration of 1 or 2 mg baclofen/animal significantly increased the gastric retention of the solid test meal (57.9 ± 6.5% and 66.6
Efeito do lipopolissacarídio bacteriano sobre o esvaziamento gástrico de ratos: avalia??o do pré-tratamento com dexametasona e azul de metileno
Collares, Edgard Ferro;Vinagre, Adriana Mendes;
Arquivos de Gastroenterologia , 2003, DOI: 10.1590/S0004-28032003000200008
Abstract: background: the nitric oxide might be a putative mediator of the decrease in gastric emptying induced by bacterial lipopolysaccharide in rats. aim: for that, we evaluated the effect of the pretreatment intravenous with dexamethasone and methylene blue in the retardation process of gastric emptying induced by intravenous application of lipopolysaccharide in rats. dexamethasone has been shown to inhibit the induction of nos ii (induced no-synthase) while the methylene blue, that blocks the soluble guanylyl cyclase, inhibits nitric oxide synthases and, in addition, inactivates nitric oxide directly. material and methods: male wistar rats, specific patogenic free, were used after a 24 hour fast and 1 hour-water withdrawn. the pretreatment was performed using dexamethasone solutions (3 and 6 mg/kg), methylene blue (2 mg/kg) or sterile vehicle. the treatment consisted in the application of lipopolysaccharide (50 mg/kg) or vehicle. the time period between the pretreatment and treatment was 10 minutes, excluding the study with dexamethasone 6 mg/kg that was 1 hour. the gastric emptying was evaluated 1 hour after the lipopolysaccharide application, except for two studies with dexamethasone 3 mg/kg in which the time periods were 2 and 8 hours. a saline solution containing phenol red was used as the test meal. the gastric emptying was determined by measuring gastric retention 10 minutes after the orogastric infusion of the test meal. results: the pretreatment with dexamethasone or methylene blue and treatment with vehicle did not have effect in the gastric emptying comparing to the control group. we found that pretreatment with dexamethasone in the studies for 1 hour and 2 hours did not interfere in the retardation of the gastric emptying produced by endotoxin. nevertheless, in the eighth period study with this drug there was a significant reduction of gastric retention in the endotoxin-treated animals in relation to the unpretreated ones. meanwhile, the pretreatment with the
Efeito do lipopolissacarídio bacteriano sobre o esvaziamento gástrico de ratos: avalia??o do pré-tratamento com Nw-nitro-L-arginine methyl ester (L-NAME)
Collares, Edgard Ferro;Vinagre, Adriana Mendes;
Arquivos de Gastroenterologia , 2006, DOI: 10.1590/S0004-28032006000300014
Abstract: background: there is evidence that nitric oxide plays a role in the decrease in gastric emptying induced by bacterial lipopolysaccharide. aim: to evaluate the effect of pretreatment with nw-nitro-l-arginine methyl to ester, one competitive inhibitor of the nitric oxide syntases, on the gastric emptying delay induced by lipopolysaccharide. material and methods: male wistar rats, spf, were used after 24 h fast and 1 h-water withdrawn. the pretreatment was done intravenously with vehicle (saline) or nw-nitro-l-arginine methyl to ester in the doses of 0.5, 1, 2.5 e 5 mg/kg. after 10 min, the animals were treated iv with lipopolysaccharide (50 mg/kg) or received vehicle (saline). the gastric emptying was evaluated 1 h after the lipopolysaccharide administration. a saline solution containing phenol red was used as the test meal. the gastric emptying was indirectly assessed by the determination of percent gastric retention of the test meal 10 min after orogastric administration. results: the animals pretreated with vehicle and treatment with lipopolysaccharide have significant rise of the gastric retention (average = 57%) in comparison with the controls receiving only vehicle (38.1%). the pretreatment with the different doses of nw-nitro-l-arginine methyl to ester did not modify per se the gastric retention in comparison with the animals pretreated with vehicle. pretreatment with nw-nitro-l-arginine methyl to ester with the dose of 1 mg/kg determined a discrete but significant reduction in the gastric retention (52%) of animals treated with lipopolysaccharide in comparison with vehicle-pretreated rats. paradoxically, animals pretreated with 2.5 or 5 mg of nw-nitro-l-arginine methyl to ester/kg followed by treatment with lipopolysaccharide displayed a significantly higher gastric retention (74.7% and 80.5%, respectively) as compared to their controls, pretreated with the same doses of the inhibitor and treated with vehicle (40.5% and 38.7%, respectively) and to those pretre
Comportamentos de ajuda no contexto urbano: um estudo experimental por meio do telefone
Silva, Abelardo Vinagre da;Günther, Hartmut;
Psicologia: Teoria e Pesquisa , 1999, DOI: 10.1590/S0102-37721999000300002
Abstract: cold and calculating interpersonal relations among residents of large cities are described in north american studies. little is known, however, about this topic in brazil. the use of the telephone as a research instrument in social experiments also is not common in brazilian's culture. an attempt was made to verify helping behavior as a function of type of home (house vs. apartment), local (center vs. periphery) and gender of the person seeking help. using the 'wrong number technique', help was solicited by phone from 320 residents in two urban areas. overall, 39,3% of the persons contacted provided help. type of home and local did not influence the rate of helping. however, female callers elicited more helping behavior than did male callers. the use the telephone as an instrument in social research proved possible. several methodological aspects needing special attention in experimental use were also discussed.
Efeito do lipopolissacarídio bacteriano sobre o esvaziamento gástrico de ratos: avalia o do pré-tratamento com dexametasona e azul de metileno
Collares Edgard Ferro,Vinagre Adriana Mendes
Arquivos de Gastroenterologia , 2003,
Abstract: RACIONAL: O óxido nítrico pode estar envolvido no retardo do esvaziamento gástrico produzido pelo lipopolissacarídio bacteriano. OBJETIVO: Avaliar o efeito do pré-tratamento com a dexametasona, bloqueadora da indu o do óxido nítrico-sintetase induzida e com o azul de metileno, que bloqueia a guanilato-ciclase, inibe as óxido nítrico-sintetases e inativa o óxido nítrico, sobre o retardo do esvaziamento gástrico determinado pelo lipopolissacarídio em ratos. MATERIAL E MéTODOS: Foram utilizados ratos Wistar, machos, ''specific patogen free'', após 24 horas de jejum alimentar. No pré-tratamento foram empregadas, via intravenosa, solu es de dexametasona (3 e 6 mg/kg), azul de metileno (2 mg/kg) e veículo estéril. O tratamento constou da administra o, via intravenosa, de lipopolissacarídio (50 mig/kg) e veículo. O intervalo entre o pré-tratamento e o tratamento foi de 10 minutos, exceto no estudo com dexametasona 6 mg/kg, que foi de 1 hora. O intervalo entre a administra o do lipopolissacarídio e a avalia o do esvaziamento gástrico foi de 1 hora, exceto nos dois estudos com dexametasona 3 mg/kg que foram de 2 e 8 horas. O esvaziamento gástrico foi avaliado, indiretamente, através da determina o da percentagem de reten o gástrica de solu o salina marcada com fenol vermelho. RESULTADOS: Os valores de reten o gástrica, nos animais pré-tratados com dexametasona ou azul de metileno e tratados com veículo, n o diferiram significativamente dos observados nos que receberam veículo nos dois momentos. Os animais pré-tratados com veículo e tratados com lipopolissacarídio apresentaram valores de reten o gástrica significativamente mais elevados que nos controles. O pré-tratamento com dexametasona n o interferiu no aumento da reten o gástrica determinado pelo lipopolissacarídio, nas primeiras 2 horas após administra o da endotoxina. Oito horas após a administra o da endotoxina, foi observada diminui o significativa da reten o gástrica nos animais pré-tratados com dexametasona e tratados com lipopolissacarídio em rela o aos que receberam veículo + lipopolissacarídio. O mesmo fen meno foi observado nos animais pré-tratados com azul de metileno e tratados com lipopolissacarídio. CONCLUS O: Os resultados sugerem o envolvimento do óxido nítrico no efeito do lipopolissacarídio sobre o esvaziamento gástrico em ratos.
Influence of Peritoneal Suture on the Formation of Abdominal Adhesions in Wistar Rats: Is Suturing Worthwhile?  [PDF]
Nathália Andrade, Michel Vinagre, Luciana Canabarro, Willy Marcus Fran?a
Surgical Science (SS) , 2013, DOI: 10.4236/ss.2013.49078
Abstract:

Purpose: The purpose of the present study was to determine the effect of peritoneal closure on the formation of abdominal adhesions by verifying their degree of damage on intestinal portions and the omentum with the abdominal wall. Given the different reports found in the literature concerning peritoneal closure mostly in obstetrics and gynecology, any objective information based on statistically tested results may be of great value in the everyday surgery practice. Material and Method: This is an experimental model on which a laparotomy is performed on the free cavity of the abdominal wall in growing rats. Young Wistar rats (approximately 1 month old) were operated through a long median xipho-umbilical abdominal incision. The animals were divided in 3 groups with fifteen rats each: in Group I, only the peritoneum was left open and all the other layers of the abdominal wall were closed; the rats in Group II had their peritoneums closed with unabsorbable cord (Prolene 4-0, Ethicon?). The abdominal wall of the rats in Group III (control) was only opened up to the musculature. The peritoneum, which remained intact and closed, was carefully prodded with the grip of tweezers to avoid lesions and/or perforations in the peritoneum. Results: There were no deaths nor incisional dehiscence and/or hernias among the animals. Nine animals of

Platelet Indices in Patients with Acute Coronary Syndrome  [PDF]
Silvia Cristina Costa, Carmen Guilherme de Matos Vinagre, Ana Paula Marte Chacra, Maria Regina Andrade de Azevedo
Journal of Biosciences and Medicines (JBM) , 2015, DOI: 10.4236/jbm.2015.311009
Abstract: The platelet indices Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and Plate-letcrit (PCT) provided by automated hematology analysis are rarely used in clinical practice. Platelets play a central role in the pathogenesis of acute coronary syndromes (ACS) and high MPV has been associated to more reactive platelets and regarded as an independent risk factor for myocardial infarction. In this study, platelet indices were evaluated in 39 patients with ACS presenting two altered biochemical parameters, C reactive protein (CRP) and creatine kinase fraction MB (CK-MB). The results obtained showed significantly higher MPV and PDW values in the group with ACS in comparison to the control group. Also observed was a weak but significant positive correlation between MPV and CK-MB. In view of findings of previous studies, which have associated macroplatelets with higher thrombotic potential our results suggest that the use of the MPV and PDW indices as additional and complementary markers may contribute to the investigation and follow-up of thrombotic risk in patients with ACS.
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