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Introduction: Otoendoscopic myringoplasty has been successfully used for repair of small to medium sized perforation using various materials. Very few studies have used this method for repair of large central perforation. Goals: To evaluate the transcanal otoendoscopic approach to reconstruct large central perforation by raising single flap. Methods Utilized: Pilot study on forty patients with chronic suppurative otitis media dry stage with large central perforation in medical college hospital and research centre was conducted. A zero degree 4 mm otoendoscope and custom made suction elevator was used for myringoplasty. Results: The perforation of thirty eight patients had healed by the end of two months. Conclusion: Otoendoscopic myringoplasty is effective in managing large central perforation and patients need to be observed for longer period to calculate the successful rate.