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Dragan Veselinovi,Aleksandar Veselinovi
Acta Medica Medianae , 2009,
Abstract: Endophthalmitis is one of the most urgent conditions in ophthalmology, characterized by the inflammation of the anterior and posterior eye segments, occurring as theconsequence of bacterial or fungal infections.The paper presents the clinical manifestations of endophthalmitis, classifications of endophthalmitis in respect to etiological and other factors which can cause this condition. A special emphasis is given to the occurrence of endophthalmitis after cataract surgery. In addition, the paper presents the clinical features of post-traumatic, endogenous and fungal endophthalmitis cases , as well as the risk factors for the occurrence of post-operative endophthalmitis, the importance of postoperative endophthalmitis prevention, with given recommendations for appropriate prophylaxis. Great importance was attached to the therapy of acute endophthalmitis based on the recommendations of the European Society of Cataract and Refractive Surgery.
Bartonella henselae as a cause of optical nerve neuritis
Vojnosanitetski Pregled , 2006, DOI: 10.2298/vsp0611971v
Abstract: Introduction. Bartonella henselae is included into the group of gramnegative bacteria that can cause not so rare disease known as catscratch disease (CSD). This disease is characterized by the specific general symptoms, and the complications in the eyes can be manifested in the form of neuroretinitis, follicular conjunctivitis and focal chorioretinitis. In this paper clinical and epidemiological characteristics of a patient with ophthalmologic complications caused by Bartonella henselae are described. We indicate diagnostic possibilities and the criteria for making the diagnosis. Case report. We presented a 42- year-old female patient with CSD symptoms, and with a registered neuritis as an ophthalmologic complication. Two weeks after the occurrence of a scratch on the hand after the contact with a cat, there was a slight lymphadenopathy of the axial area of the left side, accompanied by light febrility and weakness. A week after these symptoms occurring, the patient complained of a reduction of the visual acuity in her left eye. The established visual acuity in the left eye was 0.1 with ophthalmological findings of a light edema of the optical disk and a partial star-like edema in the nasal half of the macula. Central scotoma was present, with the extension of the blind spot and the constriction of central isopter of the left eye visual field. Fluorescein biomicroscopy revealed an intensive leaking of fluoresceins at the level of optical disk and macular region in an early arterial phase, without the appearance of pathological phenomena at the level of retinal blood vessels. With the application of doxycyline 100 mg two times a day, and systemic application of prednisolone (at the initial doses of 120 mg), after a two-week period, there was a full recovery of the visual acuity, out the optical disk edema, and the presence of light edema in the left eye macula receded. The complete disappearance of the edema in the macula was registered four weeks following the application of the therapy. Conclusion. Cat-scratch disease can be recognized by means of characteristic general symptoms, and it must be considered in persons with ophthalmologic picture of neuroretinitis. In spite of the good prognosis for the general condition of a patient, it is advised to apply antibiotic therapy in the cases where ophthalmologic complications appear. We recommend the application of doxycyline 100 mg two times a day, for a month. When pronounced edema of the optical disk and edema in the macula are present, a systematic application of corticosteroids is necessary.
Dragan Veselinovi,Milo? Jovanovi?
Acta Facultatis Medicae Naissensis , 2005,
Abstract: In addition to diabetic retinopathy, optic nerve diseases of diabetic origin also occupy a significant place in routine ophthalmologic practice and they are one of the most important complications of diabetes. The paper deals with the systematization and classification of optic nerve diabetes - induced diseases into various clinical forms. The patients with congenital bilateral optic nerve atrophy and juvenile insulin-dependent diabetes, diabetic papillopathy, anterior ischemic optic neuropathy, posterior ischemic optic neuropathy, and retrobulbar neuritis are described as the most common clinical forms of optic nerve diabetes- induced diseases. Possible etiopathogenetic mechanisms are analyzed, the most important of which are hereditary, toxic, metabolic, ischemic and transudative ones. In order to assess the signs of optic nerve disease we analyzed 600 diabetic patients. The presence of optic nerve disease was established in 24 cases. Compared to controls, statistical significance was demonstrated regarding the number of patients with optic nerve disease in the group of examinees (p<0.01). One of the essential characteristics of optic nerve diabetes- induced disease is that the optic nerve involvement was not always associated with evident signs of diabetic retinopathy and that in several cases optic nerve disease even preceded the occurrence of retinopathy.
Milo? Jovanovi?,Dragan Veselinovi
Acta Medica Medianae , 2005,
Abstract: The paper describes a patient with clinical signs of Posner-Schlossman syndrome as well as with some characteristics unusual for the disease. The patient was a fellow-ophthalmologist with glaucoma cyclitic crisis on his right eye and clinical presentation typical of this disease. What was unusual about this patient with Posner-Schlossman syndrome was his age. He was 70 years old at the time of the first disease onset , which is contrary to the assertion that Posner-Schlossman syndrome appears in younger adults, and never after the age of 55. The second unusual trait of this case was that disturbance of circulation and ischemias of cilliary body were the possible cause of Posner-Schlossman syndrome. This was confirmed by means of NMR contrast, which verified a poor arborization of internal carotid artery and ischemia of the area supplied by it, as well as of cillliary body, through its branch - ophthalmic artery that is a ciliares longae. Posner-Schlossman syndrome with its first onset may appear even in the old age. Ischemia of cilliary body may be the cause of the syndrome.
Orbital dermoid and epidermoid cysts: Case study
VeselinoviDragan,Krasi? Dragan,Stefanovi? Ivan,Veselinovi? Aleksandar
Srpski Arhiv za Celokupno Lekarstvo , 2010, DOI: 10.2298/sarh1012755v
Abstract: Introduction. Dermoid and epidermoid cysts of the orbit belong to choristomas, tumours that originate from the aberrant primordial tissue. Clinically, they manifest as cystic movable formations mostly localized in the upper temporal quadrant of the orbit. They are described as both superficial and deep formations with most frequently slow intermittent growth. Apart from aesthetic effects, during their growth, dermoid and epidermoid cysts can cause disturbances in the eye motility, and in rare cases, also an optical nerve compression syndrome. Case Outline. In this paper, we described a child with a congenital orbital dermoid cyst localized in the upper-nasal quadrant that was showing signs of a gradual enlargement and progression. The computerized tomography revealed a cyst of 1.5-2.0 cm in size. At the Maxillofacial Surgery Hospital in Ni , the dermoid cyst was extirpated in toto after orbitotomy performed by superciliary approach. Postoperative course was uneventful, without inflammation signs, and after two weeks excellent functional and aesthetic effects were achieved. Conclusion. Before the decision to treat the dermoid and epidermoid cysts operatively, a detailed diagnostic procedure was necessary to be done in order to locate the cyst precisely and determine its size and possible propagation into the surrounding periorbital structures. Apart from cosmetic indications, operative procedures are recommended in the case of cysts with constant progressions, which cause the pressure to the eye lobe, lead to motility disturbances and indirectly compress the optical nerve and branches of the cranial nerves III, IV and VI.
Operation of traumatic cataract with metal foreign body in the lens
VeselinoviDragan,Stefanovi? Ivan,Jovanovi? Milo?,Veselinovi? Aleksandar
Srpski Arhiv za Celokupno Lekarstvo , 2011, DOI: 10.2298/sarh1104216v
Abstract: Introduction. We present a patient with perforative eye injury, a metal foreign body in the lens and traumatic cataract. The paper emphasises the importance of phacoemulsification in case of patients with a traumatic cataract and the presence of a metal foreign body. Case Outline. A 41-year-old patient had a perforative wound of the cornea caused by a metal foreign body that also perforated the anterior lens capsule and remained in the paracentral anterior part of the lens. The injury, which happened upon hitting of a hammer against a metal object, showed the presence of a tangential wound of the cornea adapted edges, and a formed anterior eye chamber. The presence of a metal spear-shaped foreign body was partly inside the anterior eye chamber and partly in the central area of the lens. The visual acuity of the injured eye was 0.2. The technique of removing the foreign body out of the lens and the phacoemulsification of the lens with the implantation of intraocular lens is presented. The paracentral wound on the cornea was not sutured because of well-adapted edges. On the first postoperative day there were no inflammatory signs, and best uncorrected visual acuity of 0.8. Conclusion. Posttraumatic cataracts with a metal foreign body in the lens require operative treatment in order to remove the foreign body, phacoemulsification and implantation of artificial lens. Because of anterior capsule lesion, special care should be taken in regard to anterior capsulorhexis and appropriate hydrodisection. Ocular hypotonia and possible damage of the posterior capsule in some cases can make phacoemulsification more difficult to perform.
Prevalence of Chlamydia trachomatis in adults with chronic conjunctivitis in Ni ava district
In?i? Nikola,Igi? Ljiljana,Veselinovi? Aleksandar,VeselinoviDragan
Srpski Arhiv za Celokupno Lekarstvo , 2012, DOI: 10.2298/sarh1204148i
Abstract: Introduction. Chlamydia trachomatis causes many infections, including eye infections. They manifest as inclusion conjunctivitis and trachoma. The agent is transmitted by dirty hands, eyeliners, medical instruments and via swimming-pool water or, in neonates, by passage through an infected birth canal. Due to the nonspecific clinical features at the beginning of the infection and delayed application of symptomatic, anti-allergic and non-specific antibiotic therapy, Chlamydia aetiology is usually established only after laboratory diagnosis in the chronic stage of infection. Objective. Determining the frequency of Chlamydia trachomatis antigen in conjunctival and genital samples of adult patients with chronic conjunctivitis in Ni ava district. Methods. Our retrospective study was carried out on 116 patients (63 female and 53 male) with clinical signs and symptoms of chronic conjunctivitis. Chlamydia trachomatis antigen was detected by a direct immunofluorescence test with labelled monoclonal antibodies. Results. From a total of 116 examined patients in 37 patients Chlamydia trachomatis antigen was detected; 17 female and 20 male. Thirty-three of the patients had a bilateral infection and four unilateral. Among 24 patients who were also tested for Chlamydia trachomatis antigen collected by ocular and genital swabs, 19 had conjunctivitis associated with urethritis/vaginitis. Conclusion. The studied group of patients showed that the common cause of the chronic conjunctivitis were bacteria, but predominantly Chlamydia trachomatis. In most cases Chlamydia infection occurred bilaterally. The majority of patients had eye Chlamydia infection associated with genital Chlamydia infection. There was no statistically significant difference in the presence of the disease regarding gender.
Aleksandar Veselinovi,Dragan Veselinovi,Zoran Radovanovi?,Mila Bojanovi?
Acta Medica Medianae , 2009,
Abstract: Ocular type 1 neurofibromatosis is an autosomal dominant phacomatosis with variable expression and the occurrence of characteristic changes in the eye. The most frequent ophthalmologic finding in the eye is the presence of characteristic iris nodules. The shared result also describes the neurofibromatosis of the upper eyelid, an optic nerve glioma, choroidal hamartomas as well as congenital glaucoma. In addition, the paper gives a detailed presentation of a patient with type 1 neurofibromatosis, with the characteristic changes on the skin, which spread on the central nervous system and characteristic changes in the eye and its adnexa.It is also points out how much a detailed ophthalmologic examination is essential for detecting and recognizing possible manifestations, as well as criteria for making correct diagnoses of ophthalmologic diseases. Furthermore, the paper presents criteria for making diagnoses of type 1 neurofibromatosis in detail, taking into account a large number of manifestations on different organs.
Stojanka Djuri?,Dragan Veselinovi,Marina Joli?
Acta Medica Medianae , 2004,
Abstract: In patients with high myopia one can notice characteristic degenerative changes of eye base that affect, in the initial phase, the posterior side of the eye, and in the developed form, the peripheral parts of retina. This paper points to the potential of application of electrophysiological methods, visual evoked potentials and PERG in assessment of the degree of the degenerative disease and following of its progression.n 15 eyes with high myopia we performed testing by means of visual evoked potentials and pattern” electroretinogram and compared the received results with the values obtained from the controls. Structured VEP and pattern” electroretinogram (PERG) was performed on Mistral-Medelec computerized machine; with angle of stimulation CHESS of 30 minutes, screen angle of 15–19 degrees and maximal CHESS contrast. We performed a total of 128 stimulations with use of surface skin electrodes and stimulus frequency of 2 Hz.In patients with high myopia, visual acuity was between 1.0 and 0.1. The average latency value of P-100 waves of PVEP in patients with high myopia was 119.4 msec and was in correlation with the reduction of visual acuity of the researched eye (p<0.05).The average values of P-100 waves amplitudes were statistically significantly lower compared to the control group (3.9 msec).The amplitude values P1 and N2 of PERG were significantly lower compared to the values from the control group (p<0.01). The decrease in amplitude value was in correlation with the decline of visual acuity and the degree of degenerative changes at eye base. Latency values of P1and N2 waves of PERG were slightly prolonged without any statistical significance.Considering that pattern” electroretinogram maintains electrical activity of inner layers of retina, most of all of ganglion cells, and PVEP records the electrical response of ganglion cells which mostly originate from macula, these methods can, therefore, give us an insight as to the degree of their damage in high myopia. In this way we can use these methods in evaluation of these patients and the assessment of functional retina damage in progressive myopia.
Plasma Focus Studies in Serbia  [PDF]
Vladimir Udovi?i?, Nikola Veselinovi, Du?an Joksimovi?, Radomir Banjanac, Dimitrije Maleti?, Dejan Jokovi?, Dragan Luki?
Journal of Modern Physics (JMP) , 2014, DOI: 10.4236/jmp.2014.52013

The plasma focus experiment in Belgrade, Serbia started in the late eighties of the last century. The historical overview of the research activity on the Belgrade plasma focus device (BPFD) will be presented in this work. The special attention has been made to the present status and the future plans for the fundamental and applied research as a part of the project of the studies of rare nuclear and particle processes in nature. BPFD is intended to operate as optimized neutron source or hard X-ray source. Using Lee model code as a reference, several upgrades of BPFD must be made: better shielding against EMI pulse, rearrangement of capacitors bank so that higher repetition rate can be achieved and also faster digital acquisition system. BPFD can be used for neutron activation or production of short-living radioisotopes. These radioisotopes will have very low activity which can be analyzed in the underground Low-Background Laboratory for Nuclear Physics, Zemun. Also, we compared the obtained experimental data (neutron yield, total current waveform, working gas pressure) with the numerical simulation code (The Lee model code) to test our plasma focus machine. Comparison between neutron yield from our experimental data and neutron scaling laws and neutron yields derived from computation using the Lee Model code shows good matching, but for better verification of the code, more experimental data are needed.

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