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Search Results: 1 - 10 of 4248 matches for " Verma Anita "
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Usefulness of Self- Help Interventions in Behavioural Research
Shweta Verma,Anita Sharma
Indian Streams Research Journal , 2012,
Abstract: Interventions to alleviate job stress have multiplied rapidly over the last two decades, paralleling the increasing recognition and acceptance of the adverse impacts of job stress on individuals and organizations. This development has been reflected in the rapid growth of the job-stress intervention literature, which has been reviewed in various ways and from a range of perspectives over the last decade. The goal of the present study was to identify models of international best practice through a comprehensive review of the job-stress intervention literature.
Modelling study of dimerization in mammalian defensins
Suresh Anita,Verma Chandra
BMC Bioinformatics , 2006, DOI: 10.1186/1471-2105-7-s5-s17
Abstract: Background Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipathicity and ability to oligomerize are considered key factors for their action. Based on structural information on human β-defensin 2, we examine homologous defensins from various mammalian species for conserved functional physico-chemical characteristics. Results Based on homology greater than 40%, structural models of 8 homologs of HBD-2 were constructed. A conserved pattern of electrostatics and dynamics was observed across 6 of the examined defensins; models backed by energetics suggest that the defensins in these 6 organisms are characterized by dimerization-linked enhanced functional potentials. In contrast, dimerization is not energetically favoured in the sheep, goat and mouse defensins, suggesting that they function efficiently as monomers. Conclusion β-defensin 2 from some mammals may work as monomers while those in others, including humans, work as oligomers. This could potentially be used to design human defensins that may be effective at lower concentrations and hence have therapeutic benefits.
Biomimetically Synthesized Aqueous Ferrofluids Having Antibacterial and Anticancer Properties  [PDF]
Lubna Sheikh, Richa Vohra, Anita Kamra Verma, Suprabha Nayar
Materials Sciences and Applications (MSA) , 2015, DOI: 10.4236/msa.2015.63029
Abstract: Synthesis of functional iron oxide nanoparticles, well dispersed in aqueous fluids still remains a challenge as its stability requires a delicate balance between electrostatic and magnetic interactions. Templated synthesis using biomolecules is useful because the biomolecules have their unique arrangement in aqueous systems that enhance stability, commonly called “biomimetic synthesis”. We have developed a one-pot in-situ, low energy process for the synthesis of highly monodispersed, Collagen Functionalized Ferrofluids (CFF) as a templating agent in an aqueous medium. The nanoparticles so obtained were characterized by X-ray diffraction (XRD), dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FTIR). The antibacterial activity in terms of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and growth inhibition has been assessed against gram positive, Staphylococcus aureus, ATCC 13709 (native strain) and in Escherichia coli, DH5α gram negative bacteria. The cytotoxicity of the CFFs on cancer cell lines human embryonic kidney (HEK), breast adenocarcinoma (MCF-7) and Ehrlich ascitic carcinoma (EAC) have also been investigated. CFFs indicated variable MIC and MBC values against S. aureus and E. coli being minimum for 1.5% CFF (MIC:23.43 μg/ml and 93.75 μg/ml and MBC: 46.87 μg/ml and 187.5 μg/ml). The observed cytotoxicity in mammalian cells indicated the susceptibility of MCF-7 breast cancer cells when compared to HEK cells.
Job Performance and Chronic Fatigue Syndrome in Nurses
Anita Sharma,Anupam Verma,Dalip Malhotra
Asian Social Science , 2010, DOI: 10.5539/ass.v6n12p167
Abstract: The current study was an attempt to examine the role of chronic fatigue syndrome in job performance of nurses by comparing with normal group. A total sample of 100 nurses from IGMC, Shimla (HP) was drawn for the purpose out of which 50 were suffering from chronic fatigue syndrome (CFS) and 50 were normal. The main findings point to the following facts: (i) On the indices of job performance viz., punctuality, public dealing, efficiency, nursing knowledge and interpersonal communication, normal group has been rated significantly higher by their doctors as compared to the CFS nurses with t-values being 4.34** p<.01; 8.22** p<.01; 7.03** p<.01; 2.32* p<.05 and 2.17* p<.05 respectively. (ii) On the variable of obedience, no significant difference was observed. (iii) Overall, there was significant difference between CFS and normal nurses on total job performance score with t value = 3.97** p<.01. The results clearly reveal the deleterious effects of CFS on the job performance.
Biotoxicity of CdS/CdSe Core-Shell Nano-Structures  [PDF]
Sreenu Bhanoth, Anuraj S. Kshirsagar, Pawan K. Khanna, Aakriti Tyagi, Anita K. Verma
Advances in Nanoparticles (ANP) , 2016, DOI: 10.4236/anp.2016.51001
Abstract: The cytotoxicity of hydrophobic QDs CdS/CdSe was tested assigning MTT assay on Human Embryonic Kidney cells (HEK-293), breast cancer cells (MCF-7) and Enrichlish Ascitices Cells (EAC). Approximately 65% bio-toxicity was observed in MCF-7 for the core-shell QDs. These QDs may also find effective applications in other optoelectronic devices. CdS/CdSe core-shell hetrostructure quantum dots (QDs) were generated by chemical reaction between the respective chalcogens and cadmium metal salt. Sulphur powder was utilized for CdS core preparation while selenium was extracted from an organoselenium compound to impart CdSe shell layer at a temperature between 150 - 200. So-prepared core-shell QDs showed good optical properties. The particle size was found to be in the range of 3 - 4 nm with spherical morphology and cubic crystal structure.
Study of prevalence and response to needle stick injuries among health care workers in a tertiary care hospital in Delhi, India
Sharma Rahul,Rasania S,Verma Anita,Singh Saudan
Indian Journal of Community Medicine , 2010,
Abstract: Background: Because of the environment in which they work, many health care workers are at an increased risk of accidental needle stick injuries (NSI). Objective: To study prevalence and response to needle stick injuries among health care workers. Materials and Methods: Study Design: Cross-sectional study. Setting: A tertiary care hospital in Delhi. Participants: 322 resident doctors, interns, nursing staff, nursing students, and technicians. Statistical Analysis: Proportions and Chi-square test. Results: A large percentage (79.5%) of HCWs reported having had one or more NSIs in their career. The average number of NSIs ever was found to be 3.85 per HCW (range 0-20). 72 (22.4%) reported having received a NSI within the last month. More than half (50.4%) ascribed fatigue as a cause in their injury. Most of the injuries (34.0%) occurred during recapping. In response to their most recent NSI, 60.9% washed the site of injury with water and soap while 38 (14.8%) did nothing. Only 20 (7.8%) of the HCWs took post-exposure prophylaxis (PEP) against HIV/AIDS after their injury. Conclusions: The occurrence of NSI was found to be quite common. Avoidable practices like recapping of needles were contributing to the injuries. Prevention of NSI is an integral part of prevention programs in the work place, and training of HCWs regarding safety practices indispensably needs to be an ongoing activity at a hospital.
Seroprevalence of hepatitis viruses in patients infected with the human immunodeficiency virus
Jain Manisha,Chakravarti Anita,Verma Vikas,Bhalla Preena
Indian Journal of Pathology and Microbiology , 2009,
Abstract: Objective: The co-infection of Hepatitis B and C viruses with HIV accelerates disease progression and also has an effect on the management of patients infected with HIV. The prevalence of HIV co-infection with hepatitis viruses varies widely. This study is planned to evaluate the prevalence of HIV co-infection with Hepatitis B and C viruses in North India. Materials and Methods: A total of 1178 patients enrolled in the ART center were retrospectively analyzed for the presence of HBV and HCV on the basis of the presence of HBsAg and anti-HCV markers. Results: In patients infected with HIV, the prevalence of co-infection with HBV was 9.9% (117/1178), the prevalence of co-infection with HCV was 6.3% (74/1178) and the prevalence co-infection with both HBV and HCV was ~1% (12/1178). Discussion: The prevalence rate of HBV and HCV are increasing in patients infected with HIV. Having acquired the knowledge about the importance of such a co-infection, it is essential that all the patients infected with HIV be screened for HBV and HCV co-infection.
A study of job satisfaction and work environment perception among doctors in a tertiary hospital in Delhi
Kaur Suminder,Sharma Rahul,Talwar Richa,Verma Anita
Indian Journal of Medical Sciences , 2009,
Abstract: Background : Many doctors are dissatisfied with their jobs, which is due to long working hours and overwork. This can affect patient care and reduce quality of care. Objectives : To study job satisfaction among doctors in a tertiary hospital in Delhi and the various factors related with it. Materials and Methods: Data collection was done among 250 doctors on tenure-based job, selected by stratified random sampling, in a teaching hospital in Delhi, by using a self-administered questionnaire. Statistical Analysis : Proportions and Chi-square tests. Results : The mean number of work-hours among doctors was 9.7 ± 2.7 hours per day, and the mean number of night shifts was 5.6 per month. About half (49.6%) of the doctors were dissatisfied with the average number of work-hours per day. Dissatisfaction was significantly more in those who had an average of> 8 work-hours per day and who had ≥8 night shifts per month. About half (45.6%) of the doctors considered their salary as ′bad,′ and this was significantly more among unmarried doctors, interns and those who had ≥8 night shifts per month. More than half (55.2%) of the doctors were dissatisfied with their choice of profession, i.e., being a doctor, as compared to other professions. Conclusions : A significant proportion of doctors were found to be dissatisfied with the average number of their work-hours and salary. Factors like the average number of work-hours per day and the number of night shifts per month were found to have a significant relation with dissatisfaction. Further studies are needed to explore how best the work-hours of doctors could be adjusted to improve their job satisfaction.
SOME IMPORTANT MEDICINAL PLANTS USED IN THE TREATMENT OF ASTHMA - A REVIEW.
Sheela Kumar,V. K. Agnihotri,Sunita Thakur,Anita Verma
International Journal of Pharma Sciences and Research , 2012,
Abstract: Ayurveda, Siddha, Unani and Folk (Tribal) medicines are the major systems of indigenous medicines. Over three-quarters of the world population relies mainly on plants and plant extracts for health care. Unlike many diseases, which can be attributed to the life style of modern man, asthma is an ancient illness. Mast cells play an important role in some type of allergic reaction because the antibody that causes the allergic reaction that is Ig E have the mast cells which contains about a thousand tiny granules. These granules are loaded with dozens of potent chemicals or mediators, the most powerful in which are histamine and a newly discovered group called leukotrienes. From the present laboratory, there are number of medicinal plants have been reported for antihistaminic/anti-asthmatic activities. Some of them are Achyranthes aspera, Tephrosia purpurea,Dolichos lablab, Eclipta alba, Jasminum sambac, Balanites aegyptiaca, Viscum album, Tridex procumbens, Glycyrrhiza glabra and Cassia fistula. Recently, Soni (2009-2011) has reported 100% inhibition ofLeukotrienes (which cause asthma) from the EtoAC fraction of Bacopa monnieri extract. It is suggested that formulation and patent of the reported medicinal plants is mandatory for further use against asthma and if possible, clinical trials should be done of these plants for their appropriate use.
Effect of Salmonella enterica subspecies enterica serovar Typhimurium and Serratia fonticola on germination of seeds of common crops
Bhoj Raj Singh, Ashvani Kumar, Sugandh Agrawal and Anita Verma
Journal of Infection in Developing Countries , 2007,
Abstract: Background: Salmonella enterica subspecies enterica serovar Typhimurium (S. e. e. Typhimurium) and Serratia fonticola were tested to determine their effects on the germination of seeds of 49 and 36 cultivars of crops, respectively.Methodology: Seeds were soaked in water containing 4.20 × 106 CFU per ml of S. e. e. Typhimurium or 4.12 × 106 CFU per ml of S. fonticola for 6 h to expose them to the pathogens before germination.Results: Salmonella e. e. Typhimurium reduced seed germination of 22 cultivars belonging to 15 plant species and 14 genera. S. e. e. Typhimurium increased germination of only one cultivar of muskmelon. Serratia fonticola inhibited seed germination of 19 cultivars belonging to 11 plant species and 10 genera.Conclusions: The study indicated that contamination of seeds by S. e. e. Typhimurium and S. fonticola significantly alters seed germination of a few cultivars of some crops. The effect (inhibition of seed germination) appeared cultivar dependent. Investigation has also indicated that it may be possible to select pathogen-resistant varieties of different crops to increase the harvest and enhance the microbial quality of the crop produced.
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