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Search Results: 1 - 10 of 130380 matches for " V.?Kubata "
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Аvtomob?lnyi Transport , 2009,
Abstract: The development of algorithms of management system’s work by the automated gear-boxes vehicles is considered and the results of their practical use on the example of the KamAZ truck are considered.
Experimental and Numerical Research of a Novel Combustion Chamber for Small Gas Turbine Engines
Tuma J.,Kubata J.,Betak V.,Hybl R.
EPJ Web of Conferences , 2013, DOI: 10.1051/epjconf/20134501091
Abstract: New combustion chamber concept (based on burner JETIS-JET Induced Swirl) for small gas turbine engine (up to 200kW) is presented in this article. The combustion chamber concept is based on the flame stabilization by the generated swirl swirl generated by two opposite tangentially arranged jet tubes in the intermediate zone, this arrangement replaces air swirler, which is very complicated and expensive part in the scope of small gas turbines with annular combustion chamber. The mixing primary jets are oriented partially opposite to the main exhaust gasses flow, this enhances hot product recirculation and fuel-air mixing necessary for low NOx production and flame stability. To evaluate the designed concept a JETIS burner demonstrator (methane fuel) was manufactured and atmospheric experimental measurements of CO, NOx for various fuel nozzles and jet tubes the configuration were done. Results of these experiments and comparison with CFD simulation are presented here. Practical application of the new chamber concept in small gas turbine liquid fuel combustor was evaluated (verified) on 3 nozzles planar combustor sector test rig at atmospheric conditions results of the experiment and numerical simulation are also presented.
Cyclical Appearance of African Trypanosomes in the Cerebrospinal Fluid: New Insights in How Trypanosomes Enter the CNS
Stefan Mogk, Andreas Meiwes, Swetlana Shtopel, Ulrich Schraermeyer, Michael Lazarus, Bruno Kubata, Hartwig Wolburg, Michael Duszenko
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0091372
Abstract: It is textbook knowledge that human infective forms of Trypanosoma brucei, the causative agent of sleeping sickness, enter the brain across the blood-brain barrier after an initial phase of weeks (rhodesiense) or months (gambiense) in blood. Based on our results using an animal model, both statements seem questionable. As we and others have shown, the first infection relevant crossing of the blood brain border occurs via the choroid plexus, i.e. via the blood-CSF barrier. In addition, counting trypanosomes in blood-free CSF obtained by an atlanto-occipital access revealed a cyclical infection in CSF that was directly correlated to the trypanosome density in blood infection. We also obtained conclusive evidence of organ infiltration, since parasites were detected in tissues outside the blood vessels in heart, spleen, liver, eye, testis, epididymis, and especially between the cell layers of the pia mater including the Virchow-Robin space. Interestingly, in all organs except pia mater, heart and testis, trypanosomes showed either a more or less degraded appearance of cell integrity by loss of the surface coat (VSG), loss of the microtubular cytoskeleton and loss of the intracellular content, or where taken up by phagocytes and degraded intracellularly within lysosomes. This is also true for trypanosomes placed intrathecally into the brain parenchyma using a stereotactic device. We propose a different model of brain infection that is in accordance with our observations and with well-established facts about the development of sleeping sickness.
Late Stage Infection in Sleeping Sickness
Hartwig Wolburg, Stefan Mogk, Sven Acker, Claudia Frey, Monika Meinert, Caroline Sch?nfeld, Michael Lazarus, Yoshihiro Urade, Bruno Kilunga Kubata, Michael Duszenko
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0034304
Abstract: At the turn of the 19th century, trypanosomes were identified as the causative agent of sleeping sickness and their presence within the cerebrospinal fluid of late stage sleeping sickness patients was described. However, no definitive proof of how the parasites reach the brain has been presented so far. Analyzing electron micrographs prepared from rodent brains more than 20 days after infection, we present here conclusive evidence that the parasites first enter the brain via the choroid plexus from where they penetrate the epithelial cell layer to reach the ventricular system. Adversely, no trypanosomes were observed within the parenchyma outside blood vessels. We also show that brain infection depends on the formation of long slender trypanosomes and that the cerebrospinal fluid as well as the stroma of the choroid plexus is a hostile environment for the survival of trypanosomes, which enter the pial space including the Virchow-Robin space via the subarachnoid space to escape degradation. Our data suggest that trypanosomes do not intend to colonize the brain but reside near or within the glia limitans, from where they can re-populate blood vessels and disrupt the sleep wake cycles.
Nonsmooth Optimization Algorithms in Some Problems of Fracture Dynamics  [PDF]
V. V. Zozulya
Intelligent Information Management (IIM) , 2010, DOI: 10.4236/iim.2010.211073
Abstract: Mathematical statement of elastodynamic contact problem for cracked body with considering unilateral restrictions and friction of the crack faces is done in classical and weak forms. Different variational formulations of unilateral contact problems with friction based on boundary variational principle are considered. Nonsmooth optimization algorithms of Udzawa’s type for solution of unilateral contact problem with friction have been developed. Convergence of the proposed algorithms has been studied numerically.
Precessing Ball Solitons as Self-Organizing Systems during a Phase Transition in a Ferromagnet  [PDF]
V. V. Nietz
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.410A3010

Precessing ball solitons (PBS) in a ferromagnet during the first order phase transition is induced by a magnetic field directed along the axis of anisotropy, while the action of the periodic field perpendicular to the main magnetic field has been analyzed. Under these conditions, the characteristics of arising equilibrium PBS are uniquely determined by the frequency of the periodic field, but the solitons with other frequencies are impossible. For such structure, the entropy increase connected with dissipation is compensated by the decrease of the entropy due to the external periodic field. It is shown that the equilibrium PBS are essentially the “self-organizing systems” that can arise spotaneously in a metastable state of ferromagnet.

Movement of Self-Organizing Solitons in Ferromagnet  [PDF]
V. V. Nietz
Applied Mathematics (AM) , 2015, DOI: 10.4236/am.2015.610155
Abstract: Precessing ball solitons (PBS) in a ferromagnet during the first order phase transition induced by a magnetic field directed along the axis of anisotropy, while the additional action of high-frequency field perpendicular to the main magnetic field, are analyzed. It is shown that the spatial motion of solitons, associated with thermal fluctuations in the crystal, does not destroy the equilibrium of self-organized PBS.
Lα Line of Dark Positronium as a Nongravitational Detection of DM  [PDF]
V. Burdyuzha, V. Charugin
Journal of Modern Physics (JMP) , 2015, DOI: 10.4236/jmp.2015.613187
Abstract: An attempt to predict the new atomic dark matter lines is done on the example of a dark lepton atom-positronium. Its Layman-alpha line with the energy near 3 GeV may be observable if the appropriate conditions are realized. For this we have studied a γ-ray excess in the center of our galaxy. In principle, this excess may be produced by the Lα line of a dark positronium in the medium with Compton scattering. The possibility of observations of an annihilation line (E~300 TeV) of dark positronium is also predicted. Other proposals to observe the atomic dark matter are shortly described. Besides, Hα line (1.3μ) of usual positronum must be observable in the direction on the center of our galaxy.
Randomization of Energy and Momentum in Statistical Mechanics  [PDF]
V. V. Paranjape
Journal of Modern Physics (JMP) , 2015, DOI: 10.4236/jmp.2015.615223
Abstract: Particle-particle collisions in materials give rise to a particle distribution in energy and momentum in such a way that a most probable distribution is realized. I will show that an evaporating liquid generates a molecular imbalance in the equilibrium energy distribution. The molecular collisions by their inherent nature are able to repair the imbalance and in so doing it is shown that the liquids cool down. Similarly an external electric field creates substantial imbalance in the momentum distribution for the electrons in ionic semiconductors. Electron-electron collisions are able to restore the imbalance and as a consequence, similar to the evaporating liquid, the electron gas loses thermal energy and cools down.
基于税收能力视角的中国税制改革 China s Tax Reform Based on the Perspective of Tax Capacity
- , 2015,
Abstract: 摘要 税收能力是研究税收制度的重要视角,科学判定税收能力是税制改革的基本前提。税收制度决定了既定条件下税收能力的高低,税收能力也影响和制约着税制改革的进程。我国近年来的经济社会发展改变了经济运行中各经济主体的税收能力及其格局。基于税收能力视角,现行税收制度在税制结构、税制体系、征管制度等方面还存在着与经济社会发展不相适应之处。为此,税制改革应基于对目前及未来税收能力的科学判断,明确税制结构优化的方向和路径,加快地方税体系建设,进一步完善税收征管制度。
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