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Dredge Volume Calculation Using Grid Volume Model at Sharm Obhur, Red Sea—A Case Study  [PDF]
V. R. Shamji
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105299
Abstract:
Calculation of dredging volume is very critical for project estimation and implementation. Many methods are available to compute the dredging volume and most of them are complex and expensive too. This paper pro-poses a simple grid volume numerical model to calculate the dredging volume. A case study conducted at Sharm Obhur, the Red Sea, using the grid volume model and quantitative analysis, was carried out. The study pointed out that the grid volume model is more precise and faster compared to other commercially available methods. The study has great practical potential for project plans, estimations and developments in the maritime sector.
Is VATS Bullectomy and Pleurectomy an Effective Method for the Management of Spontaneous Pneumothorax?  [PDF]
Ramzi A. Addas, Farid M. Shamji, Sudhir R. Sundaresan, Patrick James Villeneuve, Andrew J. E. Seely, Sebastien Gilbert, Donna E. Maziak
Open Journal of Thoracic Surgery (OJTS) , 2016, DOI: 10.4236/ojts.2016.63005
Abstract: Spontaneous pneumothorax, primary or secondary, is a common medical emergency for which specific indications for surgical intervention are well defined in selected patients. The traditional surgical approach has been by limited thoracotomy using axillary or posterolateral incision. With the advent of video-assisted minimally invasive technique in the last 20 years the traditional approach is infrequently used. The definitive operation to prevent recurrent pneumothorax by surgical approach requires bullectomy and parietal pleurectomy. The recurrence rate after the traditional open surgical approach has been low at <2%. On the other hand, video-assisted thoracoscopic surgery, although better tolerated has a higher recurrence rate at 5% [1]. Information on post-operative morbidity and mortality are lacking. For this reason, we have reviewed our experience at one institution on the outcome of the VATS approach. We found that prolonged post- operative air leak is the most common complication and cigarette smoking remains an important associated factor.
Subarachnoid-Pleural Fistula: Applied Anatomy of the Thoracic Spinal Nerve Root
Mohammed F. Shamji,Sudhir Sundaresan,Vasco Da Silva,Jean Seely,Farid M. Shamji
ISRN Surgery , 2011, DOI: 10.5402/2011/168959
Abstract: Subarachnoid-pleural fistula (SPF) is a rare complication of chest or spine operations for neoplastic disease. Concomitant dural and parietal pleural defects permit flow of cerebrospinal fluid into the pleural cavity or intrapleural air into the subarachnoid space. Dural injury recognized intraoperatively permits immediate repair, but unnoticed damage may cause postoperative pleural effusion, intracranial hypotension, meningitis, or pneumocephalus. We review two cases of SPF following surgical intervention for chest wall metastatic disease to motivate a detailed review of the anatomy of neural, osseous, and ligamentous structures at the intervertebral foramen. We further provide recommendations for avoidance and detection of such complication. 1. Introduction Subarachnoid-pleural fistula (SPF) is an abnormal communication between the subarachnoid and pleural spaces that normally can arise from blunt or penetrating trauma or as a complication of chest operation. This occurs infrequently following cardiothoracic surgery for lung or chest wall [1] resection and closure of patent ductus arteriosus [2], spine surgery for transthoracic discectomy [3, 4], removal of vertebral tumors [5], or spinal fusion [6]. Symptoms develop from the accumulation of pleural fluid, the reduced volume of cerebrospinal fluid (CSF), the presence of intracranial air, or the development of meningitis, with outcomes ranging from benign to catastrophic. This complication most frequently occurs in the setting of a tumour that occupies the costovertebral angle requiring extrapleural dissection, excessive rib retraction, or disarticulation of the costotransverse joint leading to nerve root avulsion or dural tear. The risk is increased when there is associated inadvertent posterior rib neck fracture. Early recognition of SPF is important for timely repair because spontaneous closure seldom occurs. Following confirmation of the SPF diagnosis by computed tomography (CT) myelography or radionuclide cisternography, conservative therapies such as lumbar drainage to divert CSF flow may be successful, though this is less likely to occur in patients who have undergone previous surgery or received radiotherapy to the affected area. Consequently, direct operative repair of the dural defect with fine non-absorbable suture and reinforcing repair with a tissue patch is often necessary for permanent definitive treatment of the established SPF [5]. This paper describes the diagnosis and management of two cases of SPF encountered by the senior author that illustrate the typical course to presentations
Continuous Multi-Parameter Heart Rate Variability Analysis Heralds Onset of Sepsis in Adults
Saif Ahmad, Tim Ramsay, Lothar Huebsch, Sarah Flanagan, Sheryl McDiarmid, Izmail Batkin, Lauralyn McIntyre, Sudhir R. Sundaresan, Donna E. Maziak, Farid M. Shamji, Paul Hebert, Dean Fergusson, Alan Tinmouth, Andrew J. E. Seely
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0006642
Abstract: Background Early diagnosis of sepsis enables timely resuscitation and antibiotics and prevents subsequent morbidity and mortality. Clinical approaches relying on point-in-time analysis of vital signs or lab values are often insensitive, non-specific and late diagnostic markers of sepsis. Exploring otherwise hidden information within intervals-in-time, heart rate variability (HRV) has been documented to be both altered in the presence of sepsis, and correlated with its severity. We hypothesized that by continuously tracking individual patient HRV over time in patients as they develop sepsis, we would demonstrate reduced HRV in association with the onset of sepsis. Methodology/Principal Findings We monitored heart rate continuously in adult bone marrow transplant (BMT) patients (n = 21) beginning a day before their BMT and continuing until recovery or withdrawal (12±4 days). We characterized HRV continuously over time with a panel of time, frequency, complexity, and scale-invariant domain techniques. We defined baseline HRV as mean variability for the first 24 h of monitoring and studied individual and population average percentage change (from baseline) over time in diverse HRV metrics, in comparison with the time of clinical diagnosis and treatment of sepsis (defined as systemic inflammatory response syndrome along with clinically suspected infection requiring treatment). Of the 21 patients enrolled, 4 patients withdrew, leaving 17 patients who completed the study. Fourteen patients developed sepsis requiring antibiotic therapy, whereas 3 did not. On average, for 12 out of 14 infected patients, a significant (25%) reduction prior to the clinical diagnosis and treatment of sepsis was observed in standard deviation, root mean square successive difference, sample and multiscale entropy, fast Fourier transform, detrended fluctuation analysis, and wavelet variability metrics. For infected patients (n = 14), wavelet HRV demonstrated a 25% drop from baseline 35 h prior to sepsis on average. For 3 out of 3 non-infected patients, all measures, except root mean square successive difference and entropy, showed no significant reduction. Significant correlation was present amongst these HRV metrics for the entire population. Conclusions/Significance Continuous HRV monitoring is feasible in ambulatory patients, demonstrates significant HRV alteration in individual patients in association with, and prior to clinical diagnosis and treatment of sepsis, and merits further investigation as a means of providing early warning of sepsis.
Multiplex Cytological Profiling Assay to Measure Diverse Cellular States
Sigrun M. Gustafsdottir, Vebjorn Ljosa, Katherine L. Sokolnicki, J. Anthony Wilson, Deepika Walpita, Melissa M. Kemp, Kathleen Petri Seiler, Hyman A. Carrel, Todd R. Golub, Stuart L. Schreiber, Paul A. Clemons, Anne E. Carpenter, Alykhan F. Shamji
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080999
Abstract: Computational methods for image-based profiling are under active development, but their success hinges on assays that can capture a wide range of phenotypes. We have developed a multiplex cytological profiling assay that “paints the cell” with as many fluorescent markers as possible without compromising our ability to extract rich, quantitative profiles in high throughput. The assay detects seven major cellular components. In a pilot screen of bioactive compounds, the assay detected a range of cellular phenotypes and it clustered compounds with similar ?annotated protein targets or chemical structure based on cytological profiles. The results demonstrate that the assay captures subtle patterns in the combination of morphological labels, thereby detecting the effects of chemical compounds even though their targets are not stained directly. This image-based assay provides an unbiased approach to characterize compound- and disease-associated cell states to support future probe discovery.
Giant Plagioclase Basalts from Northeastern Deccan Volcanic Province, India: Implications for Their Origin and Petrogenetic Significance  [PDF]
Reddy V. R. Talusani
International Journal of Geosciences (IJG) , 2012, DOI: 10.4236/ijg.2012.35103
Abstract: The giant plagioclase basalts (GPBs) with plagioclase phenocrysts that reach up to 3 cm in length are found near Jabalpur in the northeastern part of the Deccan Volcanic Province (DVP). The thickness of the basalt flow (flow 6) that contains the GPBs is ~ 20 m. Plagioclase phenocysts (An58 - An64) in the GPBs display many features of magma mixing (e.g., resorption, reverse zoning). Of the nine flows in the Jabalpur section, the GPBs (flow 6) with lowest Mg#s (38 - 43) and MgO (4.16 - 5.08 wt%), Ni and Cr abundances are the most evolved compositions. In addition, these GPBs have highest abundances of incompatible elements (TiO2, P2O5, Nb, Zr, Sr and Ba). The GPBs are compositionally similar to the well-studied Mahabaleshwar lavas of the western DVP. This new occurrence of GPBs has implications for existence of local crustal magma chambers, feeders and vents in the northeastern part of the DVP.
Aggression questionnaire scores in extremely violent male prisoners, male bodybuilders, and healthy non-violent men  [PDF]
Henning Vr?y
Open Journal of Psychiatry (OJPsych) , 2013, DOI: 10.4236/ojpsych.2013.33029
Abstract:

Two aggression questionnaires, the Revised Swedish Version (AQ-RSV) of the Buss-Perry Aggression Questionnaire (AQ) and the shortened and refined version by Bryant and Smith (BS-AQ) were compared. Both questionnaires identified subscore levels of aggression and there were significant differences between the groups. On the AQ-RSV subscales, the violent inmates showed statistically significantly more aggression for Hostility (p = 0.000), Anger (p = 0.000), Physical Aggression (p = 0.000) and Verbal Aggression (p = 0.01) than the healthy (non-violent) men. The bodybuilders, all “on” performance-enhancing substances, scored significantly higher on the Physical Aggression subscale than the healthy men (p = 0.000). Compared to the bodybuilders, the violent inmates scored significantly higher on the Anger (p = 0.02) and Hostility (p = 0.002) subscales. For the BS-AQ, where general variance was higher than for the original AQ, some of the above mentioned relationships were different. The violent inmates still scored significantly higher than the healthy men for Hostility (p = 0.000), Anger (p = 0.006) and Physical Aggression (p = 0.000), but not for Verbal Aggression. The inmates scored significantly higher than the bodybuilders for Anger (p = 0.006) and Verbal Aggression (p = 0.006), and the bodybuilders scored higher than the healthy men on the Physical Aggression (p = 0.002) subscale only. These and other more complex relationships are discussed in the light of previous findings. Thus the BS-AQ resulted in more sharply defined relationships and, at the same time, showed some important differences between the groups studied. Verbal Aggression does not seem to distinguish violent inmates from healthy men. Angry bodybuilders tend to express their aggression through Physical Aggression.

The Norwegian 22 July 2011 Terror Acts and Mass Murder: Insanity, Evilness or Both?  [PDF]
Henning Vr?y
Open Journal of Psychiatry (OJPsych) , 2014, DOI: 10.4236/ojpsych.2014.44039
Abstract: This review presents unique information rarely seen in a description of a politically extreme right wing terrorist. During the trial following the terror acts in Norway on July 22nd 2011, the author, a forensic psychiatrist was at the time engaged by a national Norwegian newspaper to comment on the court proceedings. The author has later thoroughly gone through all available background material such as the terrorist’s childhood, relationship to his mother, childhood psychological evaluation, the interviews made by the forensic psychiatrists and information from the police documents. This information is shared in the review. The author also discusses how it was possible for two pairs of court appointed experienced forensic psychiatrists to arrive at completely different conclusions. One pair concluded with insanity due to Paranoid Schizophrenia and the second pair found no signs of psychotic disorder at all and concluded with Narcissistic Personality Disorder. The court found the terrorist capable to stand trial and sentenced him to 21 years in preventive detention with 10 years to be served before the possibility to apply for an appeal.
On Congruences Induced by Certain Relations on “Semigroups”  [PDF]
K. V. R. Srinivas
Advances in Pure Mathematics (APM) , 2015, DOI: 10.4236/apm.2015.59054
Abstract: In his paper “On quasi-separative ‘semigroup’s’”, Krasilnikova, Yu. I. and Novikov, B. V. have studied congruences induced by certain relations on a “semigroup”. They further showed that if the “semigroup” is quasi separative then the induced congruence is a semilattice congruence. In this paper we continue the study of these relations and the induced congruences i.e., the congruences induced by certain relations on ‘‘semigroup’s”. In this paper mainly it is observed that if S is a quasi-separative and regular “semigroup” then the necessary and sufficient condition for \"\"to be the smallest semilattice congruence η is obtained.
A Motor Management Strategy for Optimising Energy Use and Reducing Life Cycle Costs  [PDF]
V. Dlamini, R. C. Bansal, R. Naidoo
Journal of Power and Energy Engineering (JPEE) , 2014, DOI: 10.4236/jpee.2014.24060
Abstract: With increasing energy costs and renewed focus on using energy in ways that support the environment, a structured approach is required to ensure that energy is used efficiently. A comprehensive motor management strategy to reduce motor life cycle costs while increasing reliability is presented. The application of energy management principles is combined with benefits that can
be obtained from using energy-efficiency motors. An economic model for determining the optimal time a motor should be replaced with a higher efficiency motor is proposed. The strategy presented incorporates benefits that can be obtained from using in-situ motor efficiency estimation and condition monitoring techniques as part of a motor management system.
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