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Search Results: 1 - 10 of 130415 matches for " V. Greenberger "
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GABA Withdrawal Modifies Network Activity in Cultured Hippocampal Neurons
H. Golan,K. Mikenberg,V. Greenberger,M. Segal
Neural Plasticity , 2000, DOI: 10.1155/np.2000.31
Abstract: Dissociated hippocampal neurons, grown in culture for 2 to 3 weeks, tended to fire bursts of synaptic currents at fairly regular intervals, representing network activity. A brief exposure of cultured neurons to GABA caused a total suppression of the spontaneous network activity. Following a washout of GABA, the activity was no longer clustered in bursts and instead, the cells fired at a high rate tonic manner. The effect of removing GABA could be seen as long as 1 to 2 days after GABA withdrawal and is expressed as an increase in the number of active cells in a network, as well as in their firing rates. Such striking effects of GABA removal may underlie part of the GABA withdrawal syndrome seen elsewhere.
(Para)bosons, (para)fermions, quons and other beasts in the menagerie of particle statistics
O. W. Greenberg,D. M. Greenberger,T. V. Greenbergest
Physics , 1993,
Abstract: After some general comments about statistics and the TCP theorem, I discuss experimental searches for violations of the exclusion principle and theories which allow for such violations.
The Disconnect Between Quantum Mechanics and Gravity
Daniel M. Greenberger
Physics , 2010,
Abstract: There is a serious disconnect between quantum theory and gravity. It occurs at the level of the very foundations of quantum theory, and is far deeper than just the matter of trying to quantize a non-linear theory. We shall examine some of the physical reasons for this disconnect and show how it manifests itself at the beginning, at the level of the equivalence principle.
Conceptual Problems Related to Time and Mass in Quantum Theory
Daniel M. Greenberger
Physics , 2010,
Abstract: The concept of proper time cannot be just taken over from classical theory and applied to quantum theory. There are a number of serious ambiguities related to it. Similarly, the concept of mass has some inconsistencies attached to it. We argue that both of these concepts only make sense if they are included in the theory as dynamical variables, and subsequently as conjugate operators. We discuss the necessary uncertainty principle between them.
Quantum Theory Looks at Time Travel
Daniel M. Greenberger,Karl Svozil
Physics , 2005, DOI: 10.1007/3-540-26669-0_4
Abstract: We introduce a quantum mechanical model of time travel which includes two figurative beam splitters in order to induce feedback to earlier times. This leads to a unique solution to the paradox where one could kill one's grandfather in that once the future has unfolded, it cannot change the past, and so the past becomes deterministic. On the other hand, looking forwards towards the future is completely probabilistic. This resolves the classical paradox in a philosophically satisfying manner.
State Involvement in Professional Nursing Development in Israel: Promotive or Restrictive
Riba, S., Greenberger, C., Reches, H
Online Journal of Issues in Nursing , 2004,
Abstract: This article describes the role of the Israeli Ministry of Health’s Nursing Division in regulating the development of the nursing profession and the nursing care provided. First, factors influencing professional nursing in Israel and the development of the Ministry of Health’s Nursing Division are presented. Then, examples of the Nursing Division’s influence on nursing practice, the process of statutory authorization used to facilitate this influence, and future Nursing Division initiatives are discussed. The article concludes by noting that, on balance, ministerial (governmental) involvement strengthens the nursing profession and the quality of nursing care provided, yet may also restrict nurses’ private concerns.
Strategies for Discovery of Small Molecule Radiation Protectors and Radiation Mitigators
Joel S. Greenberger,Michael W. Epperly
Frontiers in Oncology , 2012, DOI: 10.3389/fonc.2011.00059
Abstract: Mitochondrial targeted radiation damage protectors (delivered prior to irradiation) and mitigators (delivered after irradiation, but before the appearance of symptoms associated with radiation syndrome) have been a recent focus in drug discovery for (1) normal tissue radiation protection during fractionated radiotherapy, and (2) radiation terrorism counter measures. Several categories of such molecules have been discovered: nitroxide-linked hybrid molecules, including GS-nitroxide, GS-nitric oxide synthase inhibitors, p53/mdm2/mdm4 inhibitors, and pharmaceutical agents including inhibitors of the phosphoinositide-3-kinase pathway and the anti-seizure medicine, carbamazepine. Evaluation of potential new radiation dose modifying molecules to protect normal tissue includes: clonogenic radiation survival curves, assays for apoptosis and DNA repair, and irradiation-induced depletion of antioxidant stores. Studies of organ specific radioprotection and in total body irradiation-induced hematopoietic syndrome in the mouse model for protection/mitigation facilitate rational means by which to move candidate small molecule drugs along the drug discovery pipeline into clinical development.
A Bell Theorem Without Inequalities for Two Particles, Using Efficient Detectors
Daniel M. Greenberger,Michael Horne,Anton Zeilinger
Physics , 2005,
Abstract: We consider an entangled two-particle state that is produced from two independent down-conversion sources by the process of "entanglement-swapping", so that the particles have never met. We prove a Greenberger-Horne-Zeilinger (GHZ) type theorem, showing that the quantum mechanical perfect correlations for such a state are inconsistent with any deterministic, local, realistic theory. This theorem holds for individual events with no inequalities, for detectors of 100% efficiency.
Antioxidant Approaches to Management of Ionizing Irradiation Injury
Joel Greenberger,Valerian Kagan,Hulya Bayir,Peter Wipf,Michael Epperly
Antioxidants , 2015, DOI: 10.3390/antiox4010082
Abstract: Ionizing irradiation induces acute and chronic injury to tissues and organs. Applications of antioxidant therapies for the management of ionizing irradiation injury fall into three categories: (1) radiation counter measures against total or partial body irradiation; (2) normal tissue protection against acute organ specific ionizing irradiation injury; and (3) prevention of chronic/late radiation tissue and organ injury. The development of antioxidant therapies to ameliorate ionizing irradiation injury began with initial studies on gene therapy using Manganese Superoxide Dismutase (MnSOD) transgene approaches and evolved into applications of small molecule radiation protectors and mitigators. The understanding of the multiple steps in ionizing radiation-induced cellular, tissue, and organ injury, as well as total body effects is required to optimize the use of antioxidant therapies, and to sequence such approaches with targeted therapies for the multiple steps in the irradiation damage response.
Going Beyond Bell's Theorem
Daniel M. Greenberger,Michael A. Horne,Anton Zeilinger
Physics , 2007,
Abstract: Bell's Theorem proved that one cannot in general reproduce the results of quantum theory with a classical, deterministic local model. However, Einstein originally considered the case where one could define an 'element of reality', namely for the much simpler case where one could predict with certainty a definite outcome for an experiment. For this simple case, Bell's Theorem says nothing. But by using a slightly more complicated model than Bell, one can show that even in this simple case where one can make definite predictions, one still cannot generally introduce deterministic, local models to explain the results.
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