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Search Results: 1 - 10 of 542364 matches for " Ulysses T. Ara?a "
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Yes to Realism! No to Non-naturalism!
Ulysses T. Araa
Kritike : an Online Journal of Philosophy , 2009,
Abstract: According to contemporary moral realism a moral property, like goodness or badness, is either a natural (descriptive) property or a non-natural (nondescriptive) property of actions or situations. Contemporary moral naturalists like Richard Boyd, Nicholas Sturgeon, and David Brink are a group of philosophers who are often referred to as Cornell realists because of their connection with Cornell University. Frank Jackson is another contemporary moral naturalist who is one of the leaders of The Canberra Planners at the Australian National University with which he is connected. Jackson defends “the most extreme form of naturalism.” Jackson’s view is considered extremeby those who disagree with him because he believes that moral properties are reducible or identical to natural properties. This view of Jackson is opposed by contemporary non-naturalists like Jonathan Dancy, Derek Parfit, and Russ Shafer-Landau for reasons which in my view are not successful. Despite Jackson’s reductionism about the ethical, the Cornell realists, nevertheless, agree with him that moral properties are natural properties.
Antimicrobial activity of three species of Phyllanthus (quebra-pedra) and its commercial product
Tássia Campos de Lima Silva,Jorge Veras Filho,Janete Magali Araújo,Ulysses Paulino Albuquerque
Revista de Enfermagem UFPE On Line , 2010,
Abstract: Objective: to determine the antimicrobial activity of three plant species of the genus Phyllanthus (P. amarus Schum. and Thom., P. tenellus Roxb. and Phyllanthus niruri L.) and its commercial dye (phytotherapic), opposite the bacteria and yeasts. Methods: we evaluated the antimicrobial activity against microorganisms by disk diffusion method, and then evaluated minimum inhibitory concentration of the best results from the microdilution method. Results: the medicinal species have antimicrobial activity to Gram-positive bacteria. The commercial dye showed significant antimicrobial activity. The extracts showed the best activity for S. aureus (P. amarus with MIC 0.16 mg / mL and P. tenellus with MIC 0.10 mg / mL), opposite to B. subtilis results were also satisfactory (P. amarus 0.25 mg / mL and P. tenellus 0.30 mg / mL). The commercial dye showed MIC greater than 1mg/ml only for S. aureus with MIC of 0.70 mg / mL, and for B. subtilis showed MIC 1.10 mg / mL. With respect to the yeast, all substances were less significant than for gram-positive bacteria, ranging from 0.70 to 1mg/ml for crude extracts and 1.10 to 1.20 mg / mL for the dyeing trade. Conclusion: this study showed the potential antibacterial and antifungal therapeutic value of these species can be better evaluated.
Renal Function at Hospital Admission and Mortality Due to Acute Kidney Injury after Myocardial Infarction
Rosana G. Bruetto, Fernando B. Rodrigues, Ulysses S. Torres, Ana P. Otaviano, Dirce M. T. Zanetta, Emmanuel A. Burdmann
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0035496
Abstract: Background The role of an impaired estimated glomerular filtration rate (eGFR) at hospital admission in the outcome of acute kidney injury (AKI) after acute myocardial infarction (AMI) has been underreported. The aim of this study was to assess the influence of an admission eGFR<60 mL/min/1.73 m2 on the incidence and early and late mortality of AMI-associated AKI. Methods A prospective study of 828 AMI patients was performed. AKI was defined as a serum creatinine increase of ≥50% from the time of admission (RIFLE criteria) in the first 7 days of hospitalization. Patients were divided into subgroups according to their eGFR upon hospital admission (MDRD formula, mL/min/1.73 m2) and the development of AKI: eGFR≥60 without AKI, eGFR<60 without AKI, eGFR≥60 with AKI and eGFR<60 with AKI. Results Overall, 14.6% of the patients in this study developed AKI. The admission eGFR had no impact on the incidence of AKI. However, the admission eGFR was associated with the outcome of AMI-associated AKI. The adjusted hazard ratios (AHR, Cox multivariate analysis) for 30-day mortality were 2.00 (95% CI 1.11–3.61) for eGFR<60 without AKI, 4.76 (95% CI 2.45–9.26) for eGFR≥60 with AKI and 6.27 (95% CI 3.20–12.29) for eGFR<60 with AKI. Only an admission eGFR of <60 with AKI was significantly associated with a 30-day to 1-year mortality hazard (AHR 3.05, 95% CI 1.50–6.19). Conclusions AKI development was associated with an increased early mortality hazard in AMI patients with either preserved or impaired admission eGFR. Only the association of impaired admission eGFR and AKI was associated with an increased hazard for late mortality among these patients.
Incidence and Mortality of Acute Kidney Injury after Myocardial Infarction: A Comparison between KDIGO and RIFLE Criteria
Fernando B. Rodrigues, Rosana G. Bruetto, Ulysses S. Torres, Ana P. Otaviano, Dirce M. T. Zanetta, Emmanuel A. Burdmann
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0069998
Abstract: Background Acute kidney injury (AKI) increases the risk of death after acute myocardial infarction (AMI). Recently, a new AKI definition was proposed by the Kidney Disease Improving Global Outcomes (KDIGO) organization. The aim of the current study was to compare the incidence and the early and late mortality of AKI diagnosed by RIFLE and KDIGO criteria in the first 7 days of hospitalization due to an AMI. Methods and Results In total, 1,050 AMI patients were prospectively studied. AKI defined by RIFLE and KDIGO occurred in 14.8% and 36.6% of patients, respectively. By applying multivariate Cox analysis, AKI was associated with an increased adjusted hazard ratio (AHR) for 30-day death of 3.51 (95% confidence interval [CI] 2.35–5.25, p<0.001) by RIFLE and 3.99 (CI 2.59–6.15, p<0.001) by KDIGO and with an AHR for 1-year mortality of 1.84 (CI 1.12–3.01, p = 0.016) by RIFLE and 2.43 (CI 1.62–3.62, p<0.001) by KDIGO. The subgroup of patients diagnosed as non-AKI by RIFLE but as AKI by KDIGO criteria had also an increased AHR for death of 2.55 (1.52–4.28) at 30 days and 2.28 (CI 1.46–3.54) at 1 year (p<0.001). Conclusions KDIGO criteria detected substantially more AKI patients than RIFLE among AMI patients. Patients diagnosed as AKI by KDIGO but not RIFLE criteria had a significantly higher early and late mortality. In this study KDIGO criteria were more suitable for AKI diagnosis in AMI patients than RIFLE criteria.
Meat quality in “in door” and “out door” production systems of poultry and swine  [PDF]
Wagner A. G. Araújo, Luiz F. T. Albino, Nilva K. Sakomura, Pedro V. R. Paulino, Anastacia M. Campos
Open Journal of Animal Sciences (OJAS) , 2011, DOI: 10.4236/ojas.2011.13010
Abstract: The meat quality can be influenced by many interacting factors before and after the slaughter. Currently more sustainable production systems are targeted in general, whether or not they have any effect on meat quality. The sustainability is a condition of agroecology and necessarily im- plies on the animal and plant association and succession. A condition for sustainability is to minimize or even eliminate the use of inputs from processes of chemical synthesis. In the case of pigs and poultry, this is feasible by adopting production systems that allows nutria- ents recycle directly on the soil at levels that do not involve pollution. Although we have the understanding that the general principles of sustainability to be observed are universal, the solution is not simple. For each situation a vi- able alternative must be sought, depending on the social, economic, ecological and cultural realities. In tropical and subtropical climates the production of pigs and poultry outdoors can be an appropriate option. This also leads to nutria- ents recycle and promotes a better energy bal- ance of the system. Among the alternatives that can be taken to introduce differentiating factors in meat production as food is the type of pro- duction system, due to its direct impact on the meat quality. These systems have a direct in- fluence through the consumed food, by the conditions of animal wellbeing, physical activity and the environment provided. The performance and meat quality depend on the interaction of genotypes, rearing conditions, pre-slaughter handling and processing of the meat and the carcass. The influence of the rearing system on the animal performance, on the carcass and finally on the meat is the result of the interactive effects among facilities, feeding level and ge-notype used in the production systems. The production of poultry and pigs more extensively tend to get a final product with its own or- ga-noleptic characteristics, changing the meat de-fault color and content, place of fat deposi- tion and the fatty acid profile deposited on the carcass.
Therapy for nifedipine-induced gingival overgrowth by saireito in rats
T Hattori, K Nakano, T Kawakami, A Tamura, T Ara, PL Wang
European Journal of Medical Research , 2009, DOI: 10.1186/2047-783x-14-11-497
Abstract: The rats had significant gingival overgrowth induced by the administration of nifedipine. The space between the submandibular incisors and the width of buccal gingiva of maxillary left first molar were macroscopically measured. The buccal gingiva was microscopically examined.Eight weeks after Saireito was administrated together with nifedipine, Saireito decreased both the incisor space and the gingiva width which had been enlarged by nifedipine and furthermore, the area of connective tissue of nifedipine + Saireito group was significantly smaller than that of nifedipine alone.In conclusion, Saireito may be clinically effective in therapy for calcium antagonist-induced gingival overgrowth.Although there are many therapeutic drugs for the treatment of hypertension, calcium (Ca2+) antagonists, such as nifedipine, verapamil, and diltiazem, are frequently used as quick-acting agents. Regrettably, however, Ca2+ antagonists cause gingival overgrowth as a side effect by an increase in collagen and fibroblast densities [1]. Since the detailed pathogenic mechanism underlying gingival overgrowth remains unknown, gingival overgrowth is treated surgically. Hence, the development of treatment based on cause is urgently needed.Recently, as a result of an in vitro experiment, we reported that the Japanese traditional medicine, Saireito (Chai-Ling-Tang in Chinese) [2], or its main component, Saiko [3], inhibits the proliferation of gingival fibroblasts, the release of basic fibroblast growth factor (bFGF), and the synthesis of type I collagen. Saireito is taken as a granulated drug with drinking water in order to cure water diarrhea, acute gastroenteritis, edema and so on. This medicine is a powdery mixture of dried extracts of 12 plants such as Bupleurum falcatum (17.5%w/w), Pinellia ternate (12.5%), Alisma orientale (12.5%), Scutellaria baicalensis (7.5%), Zizyphus vulgaris (7.5%) etc. [4]. In addition, the chemical components of Saireito have been clarified by analysis with HPLC
Macrolide antibiotics like azithromycin increase lipopolysaccharide-induced IL-8 production by human gingival fibroblasts
A Kamemoto, T Ara, T Hattori, Y Fujinami, Y Imamura, P-L Wang
European Journal of Medical Research , 2009, DOI: 10.1186/2047-783x-14-7-309
Abstract: The effect of macrolide antibiotics [erythromycin (EM), azithromycin (AZM) and josamycin (JOM)] on HGFs proliferation were examined by MTT assay. HGFs were treated with LPS from Porphyromonas gingivalis (PgLPS) and macrolide antibiotics, and IL-6, IL-8 and PGE2 levels were evaluated by ELISA. MMPs were detected by gelatin zymography.AZM slightly but significantly decreased HGFs proliferation, while EM and JOM did not affected. AZM increased PgLPS-induced IL-8 production dose-dependently, while AZM did not alter IL-6 and PGE2 productions. EM and JOM did not altered PgLPS-induced IL-6, IL-8 and PGE2 productions. All macrolide antibiotics did not alter MMPs production. These results indicate that macrolide antibiotics have no direct anti-inflammatory effect. However, the use of the inhibitors of cell signaling pathway failed to reveal the mechanism that AZM enhanced PgLPS-induced IL-8 production.These results suggest macrolide antibiotics have an indirect anti-inflammatory effect as a result of their antimicrobial properties. Because AZM increased LPS-induced IL-8 production by HGFs, the possibility is considered that neutrophils may be migrated to periodontal tissue and phagocytize the periodontopathic bacteria more efficiently.Caries and periodontal disease are two major oral diseases and are considered to be biofilm infections diseases [1]. In particular, periodontal disease is highly prevalent and can affect most of the world population. Periodontal disease is accompanied by inflammation of the gingiva and destruction of periodontal tissues, leading to alveolar bone loss in severe clinical cases.To date, the effects of macrolide antibiotics on periodontal disease are examined in vitro and in vivo. Macrolide antibiotics are be classified into 14-, 15 and 16-membered ring. The representative drugs in their groups are erythromycin (EM), azithromycin (AZM) and josamycin (JOM), respectively. In particular, AZM has a good tissue penetration property [2-5] and inhibits bi
Nucleon magnetic moments in light-front models with quark mass asymmetries
Araújo, W. R. B. de;Trevisan, L. A.;Frederico, T.;Tomio, L.;Dorokhov, A. E.;
Brazilian Journal of Physics , 2004, DOI: 10.1590/S0103-97332004000500044
Abstract: we show that the systematic inconsistence found in the simultaneous fit of the neutron and proton magnetics moments in light-front models, disappears when one allows an asymmetry in the constituent quark masses. the difference between the constituent quarks masses is an effective way to include in the nucleon model the effect of the attractive short ranged interaction in the singlet spin channel.
Toroidal geometry and plasma column displacement corrections in the analysis of Mirnov oscillations
Araújo, M.S.T.;Vannucci, A.;Oliveira, K.A.;
Brazilian Journal of Physics , 2002, DOI: 10.1590/S0103-97332002000100024
Abstract: the influence of the toroidal geometry, and the plasma column displacement, over the usual tokamak poloidal magnetic field configuration was investigated for circular plasmas through a series of simulations. the results obtained clearly showed the existence of a change in phase modulation of the mirnov signals, which are not usually considered when the magnetic signals are fourier analyzed in the frame of cylindrical approximation, that is, by neglecting any possible toroidal effect. furthermore, if the occasional displacements of the plasma column in tokamaks are considered, some differences on the mode composition are also observed. these discrepancies, however, do not seem to affect the analysis of the magnetic signals as strongly as in the former case, when toroidal effects are neglected.
Efeito de sais quaternários de am?nio na organofiliza??o de uma argila bentonita nacional
Barbosa, R.;Araújo, E. M.;Oliveira, A. D. de;Melo, T. J. A. de;
Ceramica , 2006, DOI: 10.1590/S0366-69132006000400009
Abstract: bentonite clay, mainly composed by montmorillonite that provides the physical properties, concentrates the majority of the national reserve (62%) in the paraíba state. the transformation of bentonite clay to organoclay is made with a simple laboratory procedure and this modification can be obtained by cation (na+ or ca2+) exchange reaction that are present on the surface and in the interlayer space of the mineral clays by quaternary ammonium salts. in this, the organoclays bentonite were preparedwith four different types of quaternary ammonium salts such as alkyldimethylbenzylammonium chloride (dodigen), esthearildimethylammonium chloride (praepagen), cethyltrimethylammonium chloride (genamin) and cethyltrimethylammonium bromide (cetremide). the organoclays were characterized by thermogravimetry, x-ray diffraction, chemical analysis and x-ray fluorescence. the results showed that the salts were incorporated in the clay structure, confirming the organophilization. the praepagen and cetremide salts presented a higher range of thermal stability.
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