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Search Results: 1 - 10 of 972 matches for " Ulrike Henckel "
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Service robots on their way? First steps of an interdisciplinary technology assessment
Michael Decker,Ulrike Henckel
Poiesis & Praxis , 2012, DOI: 10.1007/s10202-012-0112-7
Human beings, technology and the idea of man
Thomas Engel,Ulrike Henckel
Poiesis & Praxis , 2008, DOI: 10.1007/s10202-008-0049-z
Abstract: La philosophie se penche depuis l’Antiquité sur le rapport entre la technique et l’homme, de nos jours spécialement dans le cadre de la philosophie de la technique. La technique est interprétée comme constante anthropologique, par laquelle l’homme peut fa onner son environnement dans son intérêt pour garantir sa survie. L’action technique est rationnelle et ciblée, elle est utilisée pour ma triser les calamités par l’usage d’outils. Comme la technique, le langage peut être reconstruit comme forme symbolique et donc comme instrument technique, comme outil, de sorte que le recours aux métaphores peut aussi être décrit comme le recours à des outils. L’usage de la technique entra ne une transformation de l’homme et des représentations qu’il a de lui-même. Dans le cadre de réflexions relevant de la philosophie de la technique, de nouvelles représentations humaines sont constituées, qui doivent se soumettre à des évaluations éthiques en tant que conséquences de la technique.
Diagnosis of Rabies via RT-PCR on Skin Samples of Wild and Domestic Animals  [PDF]
Ulrike Zieger
Open Journal of Veterinary Medicine (OJVM) , 2015, DOI: 10.4236/ojvm.2015.59026
Abstract: In developing countries, brain tissues from rabies suspect animals are not always available for diagnosis for a variety of reasons, such as lack of transport to submit a carcass or the difficulty of removing an animal’s head or brain under field conditions. To enable diagnosis in such cases, there is a need for a reliable method, using an alternative non-neural tissue, which can be removed and submitted to the diagnostic laboratory without special training or equipment. In human medicine, skin is used successfully for the detection of rabies virus antigen using RT-PCR technology. Little work has been done in animals using RT-PCR on skin or extracted hair follicles. The current study was conducted in Grenada on skin from 36 wild and domestic animals, in which rabies virus infection had been confirmed in brain tissue via the direct fluorescent antibody (DFA) test, and in 31 negative control animals. RT-PCR on skin yielded a sensitivity of 97.2% (35/36) and a specificity of 100% (31/31). It is concluded that the examination of skin samples via RT-PCR provides a valuable diagnostic alternative in those cases where brain tissue is not readily available.
The Degree of Fat Unsaturation in the Tissue and Potential Immune Response of Broiler Fed Chlorella sp.
Sugiharto,P Henckel,C Lauridsen
Journal of Animal Production , 2010,
Abstract: This study was carried out to investigate the effect of Chlorella sp. administered in the diet of broilers on the degree of fat unsaturation, ratio of EPA to AA in the tissue and potential immune response of broiler. A total of 90 heads of one-day-old Ross chicks were assigned in completely randomized design by 3 dietary treatments with 6 repetitions and 5 chicks in each pen. The diets were T1: control (basal diet without enrichment with Chlorella sp.); T2: basal diet enriched with 5-g of Chlorella sp./kg feed; T3: basal diet enriched with 10-g of Chlorella sp./kg feed. Skinless breast meat was sampled for FA determination at d-36. Chickens were vaccinated at d-6 and d-17 with live vaccine against ND to activate antibodies production, and then 2 ml of blood was collected at d-24 for IgG and IgM quantification. Administration of Chlorella sp. in broiler’s diet had no significant effect on the degree of fat unsaturation, the ratio between EPA and AA contained in the breast muscle and the concentration of IgG and IgM of broiler. In conclusion administration of Chlorella sp. from tropical marine origin in the diet of broiler has no significant effect on the degree of fat unsaturation, ratio of EPA to AA in the tissue, and potential immune response of broiler. The culture temperature in which the Chlorella sp. was cultivated may affect the FA composition of Chlorella sp. (Animal Production 12(2): 96-99 (2010)Abbreviations: AA: arachidonic acid, ALA: α-linolenic acid, EPA: eicosapentaenoic acid, FA: fatty acids, LA: linoleic acid, PGE2: Prostaglandin E2, PUFA: polyunsaturated fatty acids, SFA: saturated fatty acidKey Words: antibody, broiler, Chlorella sp., fatty acid, PUFA
The Discursive Constitution of Ocean Sustainability  [PDF]
Ulrike Kronfeld-Goharani
Advances in Applied Sociology (AASoci) , 2015, DOI: 10.4236/aasoci.2015.512030
Abstract: As part of a search for political responses to protect and conserve marine ecosystems, this study explores the discourse on ocean affairs with a special emphasis on the articulation of the concept of sustainability. Drawing on the discourse theory of Ernesto Laclau and Chantal Mouffe, it is argued that post structuralism offers important insights on the construction of the discourse on maritime-related affairs. The analysis shows that the discourse on ocean affairs is closely tied to the empty signifier “management”, while the analysis of the empty signifier “sustainability” confirms the traditional three dimensional structure comprising economic, social and environmental dimensions, supplemented by an institutional one. The article shows that the use of such signifiers is necessary to define sustainability in all its complexity. In this context, it is argued that Laclau and Mouffe’s discourse theory provides an approach to grasp the ambiguity of the concept of sustainability. It helps to explain the practice of institutions in rephrasing existing objectives and activities in compliance with sustainability without really changing their business as usual approach. The paper concludes with an estimation of how useful it is to adhere to sustainability in ocean affairs especially in view of the complexity, uncertainty and continuous change of marine ecosystems.
MediPlEx - a tool to combine in silico & experimental gene expression profiles of the model legume Medicago truncatula
Kolja Henckel, Helge Küster, Leonhard J Stutz, Alexander Goesmann
BMC Research Notes , 2010, DOI: 10.1186/1756-0500-3-262
Abstract: Using our new analysis tool, MediPlEx (MEDIcago truncatula multiPLe EXpression analysis), expression data from EST experiments, oligonucleotide microarrays and Affymetrix GeneChips? can be combined and analyzed, leading to a novel approach to integrated transcriptome analysis. We have validated our tool via the identification of a set of well-characterized AM-specific and AM-induced marker genes, identified by MediPlEx on the basis of in silico and experimental gene expression profiles from roots colonized with AM fungi.MediPlEx offers an integrated analysis pipeline for different sets of expression data generated for the model legume Medicago truncatula. As expected, in silico and experimental gene expression data that cover the same biological condition correlate well. The collection of differentially expressed genes identified via MediPlEx provides a starting point for functional studies in plant mutants. MediPlEx can freely be used at http://www.cebitec.uni-bielefeld.de/mediplex webcite.Medicago truncatula is a model plant for the functional analysis of legume biology [1]. The ability to interact with beneficial microbial organisms leading to the formation of nitrogen- fixing root nodules [2] and to phosphate-acquiring arbuscular mycorrhizal (AM) roots [3] is one of the main distinctive features of the legume family. AM interactions between the host root and the fungal partner are a particularly interesting field of research, since more than 80% of land plants depend on an efficient AM for the uptake of nutrients, primarily phosphate [4]. By recruiting the basic genetic programme allowing microbial infection during AM [5], legumes such as Medicago truncatula evolved the capacity to enter a second beneficial interaction: the nitrogen-fixing symbiosis with the soil bacterium Sinorhizobium meliloti [6]. Symbiotic nitrogen fixation allows legume plants such as Medicago truncatula to grow on nitrogen-depleted soils and to develop protein-rich seeds, properties exploi
Standardized volumetric 3D-analysis of SPECT/CT imaging in orthopaedics: overcoming the limitations of qualitative 2D analysis
Michael T Hirschmann, Christopher R Wagner, Helmut Rasch, Johann Henckel
BMC Medical Imaging , 2012, DOI: 10.1186/1471-2342-12-5
Abstract: We propose a method for normalizing orthopaedic SPECT/CT data that enables standardised 3D volumetric quantitative measurements and comparison among patients. Our method is based on 3D localisation using clinically relevant anatomical landmarks and frames of reference, along with intensity value normalisation using clinically relevant reference regions. Using the normalised data, we describe a thresholding technique to distinguish clinically relevant hot spots from background activity.Using an exemplar comparison of two patients, we demonstrate how the normalised, 3D-rendered data can provide a richer source of clinical information and allow quantitative comparison of SPECT/CT measurements across patients. Specifically, we demonstrate how non-normalized SPECT/CT analysis can lead to different clinical conclusions than the normalized SPECT/CT analysis, and that normalized quantitative analysis can be a more accurate indicator of pathology.Conventional orthopaedic frames of reference, 3D volumetric data analysis and thresholding are used to distinguish clinically relevant hot spots from background activity. Our goal is to facilitate a standardised approach to quantitative data collection and comparison of clinical studies using SPECT/CT, enabling more widespread clinical use of this powerful imaging tool.SPECT/CT combines a high resolution anatomical 3D computerized tomography (CT) and a single photon emission computerized tomography (SPECT) as functional imaging, which provides 3D information about biological processes into a single imaging modality. Along with the fusion of these images the metabolic activity in a region of interest can be accurately allocated to specific anatomical areas [1-3]. Until recently, registration of the functional images (SPECT) with the structural images (CT) has been difficult due to SPECT's poor spatial resolution (3-10 mm) and its high variability in identifying anatomical landmarks [4,5]. With the advent of integrated SPECT/CT techno
Long-Term Impact of Preterm Birth on Exercise Capacity in Healthy Young Men: A National Population-Based Cohort Study
Jenny Svedenkrans, Ewa Henckel, Jan Kowalski, Mikael Norman, Kajsa Bohlin
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080869
Abstract: Background Increasing numbers of survivors of preterm birth are growing into adulthood today. Long-term health-effects of prematurity are still poorly understood, but include increased risk for diabetes, obesity and cardiovascular diseases in adult life. To test if reduced physical fitness may be a link in the causal chain of preterm birth and diseases in later life, the association of preterm birth and adult exercise capacity was investigated. The hypothesis was that preterm birth contributes independently of other risk factors to lower physical fitness in adulthood. Methods and Findings Population-based national cohort study of all males conscripting for military service in 1993–2001 and born in Sweden 1973–1983, n = 218,820. Data were retrieved from the Swedish Conscript Register, the Medical Birth Register and the Population and Housing Census 1990. Primary outcome was the results from maximal exercise test (Wmax in Watt) performed at conscription. Association to perinatal and socioeconomic risk factors, other co-variates and confounders were analysed. General linear modelling showed that preterm birth predicted low Wmax in a dose-response related pattern, with 25 Watt reduction in Wmax for the lowest gestational ages, those born ≤27 weeks. Low birth weight for gestational age also independently predicted low Wmax compared to normal and high birth weight (32 Watt reduction for those with a birth weight Standard Deviation Score <2). Low parental education was significantly associated with reduced Wmax (range 17 Watt), as well as both low and high current BMI, with severe obesity resulting in a 16 Watt deficit compared to Wmax top performance. Conclusion Being born preterm as well as being born small for gestational age predicts low exercise capacity in otherwise healthy young men. The effect size of being born preterm equal or exceed that of other known risk factors for unfitness in adults, such as low parental education and overweight.
Kompetenzorientierung im Fremdsprachenunterricht: was heiβt das eigentlich?
Arras, Ulrike;
Pandaemonium Germanicum , 2009, DOI: 10.1590/S1982-88372009000100011
Abstract: in recent years, the teaching of foreign languages in schools, universities and other institutions involved with language learning has faced several changes and new orientations. the main reason for these changes certainly is the common european framework of languages, published in 2001 by the european council. in germany we additionally develop new educational standards, considering as representative examples english and french as first foreign languages taught in our school system (kultusministerkonferenz (ed.) 2004; tesch et al. (eds.) 2008). normally, such changes in educational systems lead to uncertainty and confusion, a context this article intends to clarify. are we now asked to design our classes, our material and our curricula in completely new modes? what consequences do teachers as well as learners face up to following these new approaches in teaching and learning? what does competence orientation mean exactly? and which chances does it offer?
Die Bibliothek der Medizinischen Universit t Graz: Visionen – Konzepte – Fakten / The library of the Medical University of Graz: visions – concepts – facts
Kortschak, Ulrike
GMS Medizin-Bibliothek-Information , 2009,
Abstract: This article gives short overview of the history and the philosophy of the Library of the Medical University of Graz. The library was founded in 2004 and developed in the last five years modern standards.
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