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Search Results: 1 - 10 of 298410 matches for " Tully Phillip J "
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Depression, anxiety, and cardiac morbidity outcomes after coronary artery bypass surgery: a contemporary and practical review

Tully Phillip J,Baker Robert A,

老年心脏病学杂志(英文版) , 2012,
Abstract: Research to date indicates that the number of coronary artery bypass graft (CABG) surgery patients affected by depression (i.e., major, minor, dysthymia) approximates between 30% and 40% of all cases. A longstanding empirical interest on psychosocial factors in CABG surgery patients highlights an association with increased risk of morbidity in the short and longer term. Recent evidence suggests that both depression and anxiety increase the risk for mortality and morbidity after CABG surgery independent of medical factors, although the behavioral and biological mechanisms are poorly understood. Though neither depression nor anxiety seem to markedly affect neuropsy?chological dysfunction, depression confers a risk for incident delirium. Following a comprehensive overview of recent literature, practical advice is described for clinicians taking into consideration possible screening aids to improve recognition of anxiety and depression among CABG surgery patients. An overview of contemporary interventions and randomized, controlled trials are described, along with suggestions for future CABG surgery research.
Depression, anxiety, and cardiac morbidity outcomes after coronary artery bypass surgery: a contemporary and practical review
Phillip J Tully,Robert A Baker
老年心脏病学杂志(英文版) , 2012,
Abstract: Research to date indicates that the number of coronary artery bypass graft (CABG) surgery patients affected by depression (i.e., major, minor, dysthymia) approximates between 30% and 40% of all cases. A longstanding empirical interest on psychosocial factors in CABG surgery patients highlights an association with increased risk of morbidity in the short and longer term. Recent evidence suggests that both depression and anxiety increase the risk for mortality and morbidity after CABG surgery independent of medical factors, although the behavioral and biological mechanisms are poorly understood. Though neither depression nor anxiety seem to markedly affect neuropsy chological dysfunction, depression confers a risk for incident delirium. Following a comprehensive overview of recent literature, practical advice is described for clinicians taking into consideration possible screening aids to improve recognition of anxiety and depression among CABG surgery patients. An overview of contemporary interventions and randomized, controlled trials are described, along with suggestions for future CABG surgery research.
The Real World Mental Health Needs of Heart Failure Patients Are Not Reflected by the Depression Randomized Controlled Trial Evidence
Phillip J. Tully, Gary Wittert, Terina Selkow, Harald Baumeister
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0085928
Abstract: Introduction International depression screening guidelines in heart failure (HF) are partly based on depression treatment efficacy from randomized controlled trials (RCTs). Our aim was to test the external validity of depression RCT criteria in a sample of real-world HF patients. Methods HF patients admitted to 3 hospitals in South Australia were referred to a HF psychologist if not already receiving current psychiatric management by psychologist or psychiatrist elsewhere. Screening and referral protocol consisted of the following; (a). Patient Health Questionnaire ≥10; (b). Generalized Anxiety Disorder Questionnaire ≥7); (c). positive response to 1 item panic attack screener; (d). evidence of suicidality. Patients were evaluated against the most common RCT exclusion criteria personality disorder, high suicide risk, cognitive impairment, psychosis, alcohol or substance abuse or dependency, bi-polar depression. Results Total 81 HF patients were referred from 404 HF admissions, and 73 were assessed (age 60.6±13.4, 47.9% female). Nearly half (47%) met at least 1 RCT exclusion criterion, most commonly personality disorder (28.5%), alcohol/substance abuse (17.8%) and high suicide risk (11.0%). RCT ineligibility criteria was more frequent among patients with major depression (76.5% vs. 46.2%, p<.01) and dysthymia (26.5% vs. 7.7%, p = .03) but not significantly associated with anxiety disorders. RCT ineligible patients reported greater severity of depression (M = 16.6±5.0 vs. M = 12.9±7.2, p = .02) and were higher consumers of HF psychotherapy services (M = 11.5±4.7 vs. M = 8.5±4.8, p = .01). Conclusion In this real-world sample comparable in size to recent RCT intervention arms, patients with depression disorders presented with complex psychiatric needs including comorbid personality disorders, alcohol/substance use and suicide risk. These findings suggest external validity of depression screening and RCTs could serve as a basis for level A guideline recommendations in cardiovascular diseases.
La socialización en el presente digital: Informalización y contextualización
Tully,Claus J.;
Revista iberoamericana de ciencia tecnolog?-a y sociedad , 2007,
Abstract: in this paper we formulate the thesis tat the present generatio of young people is socializae mainly through the use of technlogy, but not only by it. nowadays, too, growth takes place in thje framework of the family, the contemporary pairs, as wella a in formal and informal environmentes. the contidion of boy or young, in addition, is still influences by tnhe social environment. this confronts boys and youngsters with new worlds of experinece that constitute them in a new generation. the new with referente to the pat is that boys and teenagers grow in a (tele)communicative way, and connected to the ntework, and through tnis activity they con postpone the learning of other social competentes. the dissolution of clear links -i.e. the informalization of relations- is correlato with the demando f devoeloping meaningful usage modes, through ways of use that require self initiative and dteremination. i.e. thorugh an individual contextualuization.
La apropiación asistemática de las nuevas tecnologías. Informalización y contextualización entre los jóvenes alemanes
Tully, Claus J.
Revista Internacional de Sociologia , 2008,
Abstract: How are new techniques appropriated and used by the youths? The use of mobile phone and Internet has become usual. Which social consequences have this flexible and “loose” dealing with the modern communication techniques? Since today it is taken for granted that we live with the network technique, it is important to know more about the way in which children and youths deal with it. It is clear that the contextualization of the “Web” and its options play a relevant role. It has to do with how software and Internet options are chosen and how they are integrated in everyday life. The embedding is a specific and subjective ability. To a degree unknown up to now, the use of technical worlds is oriented by motivations, since it mainly depends on the individual interest that precedes the use of the multimedia world. German youths appropriate the supply for surfing on the data highways in a playful way. The social forming that goes with this kind of appropriation of technique has been scarcely researched, even when it implies new risks. Here it is intended to reflect about this process and its possible effects, such as social inequity and exclusion (the so called “digital divide”). Cómo se apropian y usan los jóvenes las nuevas tecnologías? El uso del teléfono móvil e Internet se ha vuelto habitual. Qué consecuencias sociales tiene este trato flexible y “relajado” con las modernas tecnológicas de la comunicación? Dado que hoy se da por sentado que convivimos con la tecnología de la red, se hace importante saber más acerca del uso que ni os y jóvenes hacen de ella. Es evidente que la contextualización de la web y sus opciones desempe an un papel destacado. Es decir, se trata de cómo son elegidas las opciones de software e Internet y cómo son incorporadas a la cotidianeidad. El “anclaje” es una capacidad específica y subjetiva. En un grado hasta ahora desconocido, la utilización de mundos técnicos es intencional, ya que depende en gran medida del interés individual que precede al uso del mundo multimedia. Los jóvenes alemanes se apropian de la oferta de navegación en las autopistas de datos de una manera lúdica. La formación social que acompa a a este tipo de apropiación de la tecnología ha sido investigada sólo en escasa medida, aun cuando encierra nuevos riesgos. Se intenta aquí reflexionar sobre este proceso y sus posibles efectos, tales como la desigualdad social y la exclusión (la llamada brecha digital).
La socialización en el presente digital: Informalización y contextualización
Claus J. Tully
Revista iberoamericana de ciencia tecnolog?-a y sociedad , 2007,
Abstract: En este trabajo se formula la tesis de que la generación de los jóvenes actuales es socializada especialmente a través del uso de la técnica, pero no sólo por medio de ella. Hoy en día, también, el crecimiento tiene lugar en el contexto de la familia, los pares etarios, así como en entornos formales e informales. La condición de ni o o la de joven, además, reciben todavía hoy influencias del entorno social. Ello confronta a los ni os y a los jóvenes con nuevos mundos de experiencias que los constituyen en una nueva generación. Lo nuevo con respecto al pasado es que ni os y adolescentes crecen de manera (tele)comunicativa, y conectados a la red, y mediante esta actividad pueden postergar el aprendizaje de otras competencias sociales. La disolución de vínculo claros -esto es, la informatización de las relaciones- se corresponde con la exigencia de desarrollar modos de empleo significativos, mediante formas de uso que requieren iniciativa y determinación propias, esto es, mediante una contextualización individual. In this paper we formulate the thesis tat the present generatio of young people is socializae mainly through the use of technlogy, but not only by it. Nowadays, too, growth takes place in thje framework of the family, the contemporary pairs, as wella a in formal and informal environmentes. The contidion of boy or young, in addition, is still influences by tnhe social environment. This confronts boys and youngsters with new worlds of experinece that constitute them in a new generation. The new with referente to the pat is that boys and teenagers grow in a (tele)communicative way, and connected to the ntework, and through tnis activity they con postpone the learning of other social competentes. The dissolution of clear links -i.e. the informalization of relations- is correlato with the demando f devoeloping meaningful usage modes, through ways of use that require self initiative and dteremination. i.e. thorugh an individual contextualuization.
Forestland and Timber Donations: Challenging Management Opportunities for Foundations  [PDF]
Phillip Lee Ward, Thomas J. Straka
Open Journal of Forestry (OJF) , 2012, DOI: 10.4236/ojf.2012.24032
Abstract: Over half of the forestland in the United States is in private hands. Just over 10 million individual and family owners control about 60% of this private forestland. Ownership of family forests changes on a regular basis; sometimes from generation to generation and sometimes to outside of the family. Often new owners are not interested in forest management and sell off the asset. Some owners attempt to ensure their family forest remains pristine and undeveloped. This is leading to timberland donations to entities that can be expected to hold the donated forest permanently and ensure sustainable forest management. University foundations and forestry schools are increasingly receiving timberland as donations. It is a way for donors to monetize the asset (with tax breaks) and protect it at the same time. Foundations have a problem with timberland as they often don’t fully understand it as an investment. Certainly there are even times when a foundation should not accept it as a donation. The nature of timberland as an investment is explained, along with basic terminology that is common use. Age class distribution and the resulting cash flow dis- tribution is explained, as well as timber volume, harvest scheduling, timberland investment analysis, tim- ber value, timber sales, and timber contracts. All of these are tools foundation board members need to evaluate timberland donations.
GeneSeer: A sage for gene names and genomic resources
Andrew J Olson, Tim Tully, Ravi Sachidanandam
BMC Genomics , 2005, DOI: 10.1186/1471-2164-6-134
Abstract: We solve the naming problem by collecting data from a variety of sources and building a name-translation database. We have also built a table of homologs across several model organisms: H. sapiens, M. musculus, R. norvegicus, D. melanogaster, C. elegans, S. cerevisiae, S. pombe and A. thaliana. This allows GeneSeer to draw phylogenetic trees and identify the closest homologs. This, in turn, allows the use of names from one species to identify homologous genes in another species. A website http://geneseer.cshl.org/ webcite is connected to the database to allow user-friendly access to our tools and external genomic resources using familiar gene names.GeneSeer allows access to gene information through common names and can map sequences to names. GeneSeer also allows identification of homologs and paralogs for a given gene. A variety of genomic data such as sequences, SNPs, splice variants, expression patterns and others can be accessed through the GeneSeer interface. It is freely available over the web http://geneseer.cshl.org/ webcite and can be incorporated in other tools through an http-based software interface described on the website. It is currently used as the search engine in the RNAi codex resource, which is a portal for short hairpin RNA (shRNA) gene-silencing constructs."Biologists would rather share their toothbrush than share a gene name":Michael Ashburner [1]. Biologists use a variety of names for genes, based on their specialization. It is a daunting task to use gene names to locate resources such as sequences or publications. For example:1. ABCA4, ABC10, ABCR, FFM, RMP, RP19, STGD, STGD1 are all names for the same gene; ATP binding cassette, sub family A (ABC1).2. The same gene name can be written in different ways; cyclinD1 versus cyclin D1.3. Researchers modify names; hPRL is used to denote the human form of PRL.4. Names can be species specific. For example, human p53 is called tumor protein 53 (Li-Fraumeni syndrome), whereas in mouse it is called tra
Microbial communities associated with ferromanganese nodules and the surrounding sediments
Benjamin J. Tully,John F. Heidelberg
Frontiers in Microbiology , 2013, DOI: 10.3389/fmicb.2013.00161
Abstract: The formation and maintenance of deep-sea ferromanganese/polymetallic nodules still remains a mystery 140 years after their discovery. The wealth of rare metals concentrated in these nodules has spurred global interest in exploring the mining potential of these resources. The prevailing theory of abiotic formation has been called into question and the role of microbial metabolisms in nodule development is now an area of active research. To understand the community structure of microbes associated with nodules and their surrounding sediment, we performed targeted sequencing of the V4 hypervariable region of the 16S rRNA gene from three nodules collected from the central South Pacific. Results have shown that the microbial communities of the nodules are significantly distinct from the communities in the surrounding sediments, and that the interiors of the nodules harbor communities different from the exterior. This suggests not only differences in potential metabolisms between the nodule and sediment communities, but also differences in the dominant metabolisms of interior and exterior communities. We identified several operational taxonomic units (OTUs) unique to both the nodule and sediment environments. The identified OTUs were assigned putative taxonomic identifications, including two OTUs only found associated with the nodules, which were assigned to the α-Proteobacteria. Finally, we explored the diversity of the most assigned taxonomic group, the Thaumarchaea MG-1, which revealed novel OTUs compared to previous research from the region and suggests a potential role as a source of fixed carbon for ammonia oxidizing archaea in the environment.
Antibiasing: High Mass-to-Light Ratios in Dense Clusters
R. Brent Tully,Edward J. Shaya
Physics , 1998,
Abstract: Modeling of the velocity field of the Local Supercluster leads to the conclusion that there must be a substantial differential between the mass-to-light ratios of most galaxies and those in a small number of special places. Specifically, M/L=1000 is indicated for the full Virgo Cluster while M/L=150 is appropriate for most environments. It is argued that a higher M/L value is characteristic of E/S0 knots, regions where the galaxy density is high and collapse time scales are short. Regions larger than galaxies where collapse is ocurring only on the order of the age of the universe, the environment where spirals and irregulars predominate, are characterized by a low M/L. Overall, the mean density of the universe is well below closure. There could be comparable total mass in the relatively rare E/S0 knots as there is in the environments dominated by spirals and irregulars.
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