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Search Results: 1 - 10 of 90 matches for " Tugrul Norgaz "
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Influence of Atrioventricular Nodal Reentrant Tachycardia Ablation on Right to Left Inter-atrial Conduction
Abdurrahman Eksik,Ahmet Akyol,Tugrul Norgaz,Izzet Erdinler
Indian Pacing and Electrophysiology Journal , 2005,
Abstract: Background: Radiofrequency (RF) catheter ablation is the procedure of choice for the potential cure of atrioventricular nodal reentrant tachycardia (AVNRT) with high success rates. We hypothesed that as a result of the close proximity of Koch’s triangle and low inter-atrial septal fibers, the RF ablation applied at this region may result in prolongation of inter-atrial conduction time (IACT). Methods: RF ablation of AVNRT was performed by conventional technique. IACT was measured before and 20 minutes after RF ablation during sinus rhythm. Number of ablations given and duration of ablation were noted. Results: The study group was consisted of 48 patients (36 [75%] female, 12 [25%] male, mean age 43.4 ± 14. 5 years). RF ablation was successful in all patients. Mean RF time was 4. 0 ± 3. 3 minutes and mean number of RF was 11. 9 ± 9, 8. The mean IACT was 70.1 ± 9.0 ms before ablation and 84.9 ± 12.7 ms after ablation, which demonstrated a significant prolongation (p<0.001). The prolongation of IACT was very well correlated with the number of (r=0.897, p<0.001) and duration of RF (r=0.779; p<0.001). Conclusions: RF ablation of AVNRT results in prolongation of IACT. The degree of prolongation is associated with the duration and number of RF ablations given. The relationship between this conduction delay and late arrhythmogenesis need to be evaluated.
Multiobjective Design Optimization of Grillage Systems according to LRFD-AISC
Tugrul Talaslioglu
Advances in Civil Engineering , 2011, DOI: 10.1155/2011/932871
Abstract: Both the entire weight and joint displacements of grid structures are minimized at the same time in this study. Four multiobjective optimization algorithms, NSGAII, SPEAII, PESAII, and AbYSS are employed to perform computational procedures related to optimization processes. The design constraints related to serviceability and ultimate strength of grid structure are implemented from Load and Resistance Factor Design-American Institute of Steel Constructions (LRFD-AISC Ver.13). Hence, while the computational performances of these four optimization algorithms are compared using different combinations of optimizer-related parameters, the various strengths of grid members are also evaluated. For this purpose, multiobjective optimization algorithms (MOAs) employed are applied to the design optimization of three application examples and achieved to generate various optimal designations using different combinations of optimizer-related parameters. According to assessment of these optimal designations considering various quality indicators, IGD, HV, and spread, AbYSSS shows a better performance comparatively to the other three proposed MOAs, NSGAII, SPEAII, and PESAII. 1. Introduction The grillage systems utilized in different structures like bridge or ship decks, building floors and space buildings, and so forth, contain traverse and longitudinal beams, which are made of available steel profiles with different cross-sections. The optimal selection of steel cross-sections from a discrete set of practically available steel profiles provides a big contribution to constructing cost of a grid structure. Therefore, either weight of grid structure or deflection of its joints is minimized according to certain design limitations prescribed by any code of practice, such as LRFD. During the design optimization of grillage systems, designer is frequently faced with a problem related to making a decision about determination of the most appropriate one between these two conflicting and commensurable objective functions. Although a displacement-related constraint is imposed as a (max span/300) according to the provisions of LRFD-AISC specification, the safety margin on displacement constraint is large when taking into account the grid structures with higher sensitivity against displacement, such as ship decks and floors of industrial buildings which bears special machines required an horizontally balanced position for a regular work. This task has been easily overcome in a way of introducing the concept of multiobjective optimization to the design applications of grid
A New Genetic Algorithm Methodology for Design Optimization of Truss Structures: Bipopulation-Based Genetic Algorithm with Enhanced Interval Search
Tugrul Talaslioglu
Modelling and Simulation in Engineering , 2009, DOI: 10.1155/2009/615162
Abstract: A new genetic algorithm (GA) methodology, Bipopulation-Based Genetic Algorithm with Enhanced Interval Search (BGAwEIS), is introduced and used to optimize the design of truss structures with various complexities. The results of BGAwEIS are compared with those obtained by the sequential genetic algorithm (SGA) utilizing a single population, a multipopulation-based genetic algorithm (MPGA) proposed for this study and other existing approaches presented in literature. This study has two goals: outlining BGAwEIS's fundamentals and evaluating the performances of BGAwEIS and MPGA. Consequently, it is demonstrated that MPGA shows a better performance than SGA taking advantage of multiple populations, but BGAwEIS explores promising solution regions more efficiently than MPGA by exploiting the feasible solutions. The performance of BGAwEIS is confirmed by better quality degree of its optimal designations compared to algorithms proposed here and described in literature.
The effects of IgM-enriched immunoglobulin preparations in patients with severe sepsis: another point of view – authors' response
Simru Tugrul
Critical Care , 2002, DOI: 10.1186/cc1846
Abstract: It was mentioned in the letter that the study protocol of Karatzas et al. regarding the design and inclusion criteria (except the age) was similar to our study design. It seems that there is another important difference between two studies, which is the subgroup analysis. Because of the limited number of patients included in our study, it was not intended to focus on the role of immunotherapy in reducing the mortality rate of severe sepsis patients. Mortality rate analyses in the subgroups of patients with different admission Acute Physiology and Chronic Health Evaluation II (APACHE II) scores were therefore not performed in our study.As Karatzas et al. noted, the APACHE II scores of our patients were lower than those found in their preliminary data analysis. This is an important difference indicating that the patient populations of their study and our study are far beyond similarity.Neurological evaluation in APACHE II scoring is based on the Glasgow coma scale (GCS) and is usually complicated by the frequent use of sedative agents in critically ill patients. It is often not clear whether to assume GCS in the absence of sedative drugs or to consider the actual GCS of the patient. Certainly this computation might be very confusing and prone to errors in data collection. In our clinical practice, we generally assume the mental state of the patients in the absence of sedative drugs while calculating the GCS. This might be the reason for relatively low levels of APACHE II scores in our study population. We agree with Karatzas et al. that the interpretation of data could be more relevant by homogenising the patients according to some clinical characteristics, especially in larger studies investigating the beneficial effects of immunotherapy in septic patients.Our study, which is the initial step of a new series of clinical investigations on this subject, was performed in a small group of patients with severe sepsis. We mentioned in our paper that recruiting this number
Diabetic Nephropathy
Armagan TUGRUL
Trakya Universitesi Tip Fakultesi Dergisi , 2002,
Abstract: Diabetic nephropathy is an important cause of end-stage renal disease. Its incidence is closely correlated with the duration of diabetes mellitus. Hyperglycemia, hypertension, smoking, advanced age, insulin resistance, male gender, high protein intake, and genetic factors have been implicated in the development of diabetic nephropathy. It has been shown that non-enzymatic protein glycation, enhanced polyol pathway, increased protein kinase C activity, glucose toxicity, biochemical defects in the extracellular matrix, and genetic factors play role in its pathogenesis. Treatment of diabetic nephropathy includes good blood glucose regulation with insulin, treatment of hypertension and microalbuminuria with ACE inhibitors, and decreased protein intake.
Diabetes Mellitus and Hypertension
Armagan TUGRUL
Trakya Universitesi Tip Fakultesi Dergisi , 2002,
Abstract: Hypertension is a major worldwide health problem. Its prevalence is 1.5-2 times higher in diabetic population than that in non-diabetic individuals. Its pathogenesis depends on diabetic nephropathy in type 1, whereas may be multifactorial in type 2 diabetes mellitus. In diabetics, angiotensin converting enzyme inhibitors are most widely preferred in the treatment of hypertension because of their numerous desirable effects. In this article, the most recent data are presented on the relationship between diabetes mellitus and hypertension, and on the epidemiology, pathogenesis, and treatments of hypertension in diabetic patients.
Can an observational case-controlled study assess survival benefits in a group of patients undergoing CABG or medical treatment sufficiently?/ Survival of patients with well-developed collaterals undergoing CABG or medical treatment: an observational case-controlled study
Tu?rul Norgaz,?evket G?rgülü
Anadolu Kardiyoloji Dergisi , 2012,
Abstract:
Avian influenza outbreak in Turkey through health personnel's views: a qualitative study
Ozlem Sarikaya, Tugrul Erbaydar
BMC Public Health , 2007, DOI: 10.1186/1471-2458-7-330
Abstract: We conducted in-depth interviews with seventeen key informants who took active roles during the avian influenza outbreak in East Turkey during the first months of 2006. We gathered information about the initial responses, the progress and management of the outbreak control, and the reactions of the health professionals and the public. The findings of the study are reported according to the topics that appeared through thematic analysis of the interview transcripts.Following the first suspected avian influenza cases, a Van Crisis Coordination Committee was formed as the coordinating and decision-making body and played an important role in the appropriate timing of decisions. The health and agriculture services could not be well coordinated owing to the lack of integrated planning in preparation for outbreak and of integrated surveillance programs. Traditional poultry practice together with the low socio-economic status of the people and the lack of health care access in the region seemed to be a major risk for animal to animal and animal to human transmission. The strengths and weaknesses of the present health system – primary health care services, national surveillance and notification systems, human resource and management – affected the inter organizational coordination during the outbreak. Open communication between the government and the public played an important part in overcoming difficulties.Although there were problems during the avian influenza outbreak in Turkey, the rapid responses of the central and regional health authorities and the performance of the health workers were the key points in controlling the epidemic. The lessons from this outbreak should provide an opportunity for integrating the preparation plans of the health and agricultural organizations, and for revising the surveillance system and enhancing the role of the primary health care services in controlling epidemic disease. Developing successful strategies based on knowledge and experienc
Developing Speaking Skills through Reading
Cagri Tugrul Mart
International Journal of English Linguistics , 2012, DOI: 10.5539/ijel.v2n6p91
Abstract: There is an increasingly high relationship between reading and speaking skills. There is no question that people who develop large reading vocabularies tend to develop large speaking vocabularies. Indeed, reading power relies on continuous improvement in vocabulary knowledge that provides communication. The importance of word knowledge, which facilitates speaking skills, has been a major resource in the development of reading skills. Therefore fostering improvement in word knowledge through wide reading has the potential for fostering improvement in speaking skills. This article focuses on how printed words relate to spoken words and finally how reading contributes to speech.
Controversies about occult hepatitis B virus infection
Ersan Ozaslan, Tugrul Purnak
World Journal of Gastroenterology , 2009,
Abstract: We read with great interest the paper written by Shi et al, reviewing the molecular characteristics and stages of chronic hepatitis B virus (HBV) infection. We think that some points in the definition of occult HBV infection (OBI) and their conclusion about the management of OBI may need further considerations.
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