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Search Results: 1 - 10 of 42989 matches for " Tsai Meng-Feng "
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Improving SCTP Performance by Jitter-Based Congestion Control over Wired-Wireless Networks
Chen Jyh-Ming,Chu Ching-Hsiang,Wu EricHsiao-Kuang,Tsai Meng-Feng
EURASIP Journal on Wireless Communications and Networking , 2011,
Abstract: With the advances of wireless communication technologies, wireless networks gradually become the most adopted communication networks in the new generation Internet. Computing devices and mobile devices may be equipped with multiple wired and/or wireless network interfaces. Stream Control Transmission Protocol (SCTP) has been proposed for reliable data transport and its multihoming feature makes use of network interfaces effectively to improve performance and reliability. However, like TCP, SCTP suffers unnecessary performance degradation over wired-wireless heterogeneous networks. The main reason is that the original congestion control scheme of SCTP cannot differentiate loss events so that SCTP reduces the congestion window inappropriately. In order to solve this problem and improve performance, we propose a jitter-based congestion control scheme with end-to-end semantics over wired-wireless networks. Besides, we solved ineffective jitter ratio problem which may cause original jitter-based congestion control scheme to misjudge congestion loss as wireless loss. Available bandwidth estimation scheme will be integrated into our congestion control mechanism to make the bottleneck more stabilized. Simulation experiments reveal that our scheme (JSCTP) gives prominence to improve performance effectively over wired-wireless networks.
The Taiwan Extragalactic Astronomical Data Center
Sébastien Foucaud,Yasuhiro Hashimoto,Meng-Feng Tsai,Nicolas Kamennoff,the TWEA-DC team
Physics , 2012,
Abstract: Founded in 2010, the Taiwan Extragalactic Astronomical Data Center (TWEA-DC) has for goal to propose access to large amount of data for the Taiwanese and International community, focusing its efforts on Extragalactic science. In continuation with individual efforts in Taiwan over the past few years, this is the first steppingstone towards the building of a National Virtual Observatory. Taking advantage of our own fast indexing algorithm (BLINK), based on a octahedral meshing of the sky coupled with a very fast kd-tree and a clever parallelization amongst available resources, TWEA-DC will propose from spring 2013 a service of "on-the-fly" matching facility, between on-site and user-based catalogs. We will also offer access to public and private raw and reducible data available to the Taiwanese community. Finally, we are developing high-end on-line analysis tools, such as an automated photometric redshifts and SED fitting code (APz), and an automated groups and clusters finder (APFoF).
Improving SCTP Performance by Jitter-Based Congestion Control over Wired-Wireless Networks
Jyh-Ming Chen,Ching-Hsiang Chu,Eric Hsiao-Kuang Wu,Meng-Feng Tsai
EURASIP Journal on Wireless Communications and Networking , 2011, DOI: 10.1155/2011/103027
Abstract:
Global expression profiling of theophylline response genes in macrophages: evidence of airway anti-inflammatory regulation
Pei-Li Yao, Meng-Feng Tsai, Yi-Chen Lin, Chien-Hsun Wang, Wei-Yu Liao, Jeremy JW Chen, Pan-Chyr Yang
Respiratory Research , 2005, DOI: 10.1186/1465-9921-6-89
Abstract: Microarray technology was used to profile the gene expression patterns of macrophages modulated by theophylline. Northern blot and real-time quantitative RT-PCR were also used to validate the microarray data, while Western blot and ELISA were used to measure the levels of IL-13 and LTC4.We identified dozens of genes in macrophages that were dose-dependently down- or up-regulated by theophylline. These included genes related to inflammation, cytokines, signaling transduction, cell adhesion and motility, cell cycle regulators, and metabolism. We observed that IL-13, a central mediator of airway inflammation, was dramatically suppressed by theophylline. Real-time quantitative RT-PCR and ELISA analyses also confirmed these results, without respect to PMA-treated THP-1 cells or isolated human alveolar macrophages. Theophylline, rolipram, etazolate, db-cAMP and forskolin suppressed both IL-13 mRNA expression (~25%, 2.73%, 8.12%, 5.28%, and 18.41%, respectively) and protein secretion (<10% production) in macrophages. These agents also effectively suppressed LTC4 expression.Our results suggest that the suppression of IL-13 by theophylline may be through cAMP mediation and may decrease LTC4 production. This study supports the role of theophylline as a signal regulator of inflammation, and that down regulation of IL-13 by theophylline may have beneficial effects in inflammatory airway diseases.Asthma is a highly prevalent health problem worldwide that may cause significant morbidity and mortality [1,2]. The mechanisms of airflow obstruction in asthma are various, including broncho-constriction with the contraction of the airway's smooth muscle, increased secretion of mucus, mucosal edema with vascular leakage, and the infiltration of inflammatory cells [3]. The pathogenesis of asthma and its susceptibility involve a complex interplay of various genetic and environmental factors, which may modulate airway inflammation and the remodeling processes that are not only present even
Including Total EGFR Staining in Scoring Improves EGFR Mutations Detection by Mutation-Specific Antibodies and EGFR TKIs Response Prediction
Shang-Gin Wu,Yih-Leong Chang,Jou-Wei Lin,Chen-Tu Wu,Hsuan-Yu Chen,Meng-Feng Tsai,Yung-Chie Lee,Chong-Jen Yu,Jin-Yuan Shih
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0023303
Abstract: Epidermal growth factor receptor (EGFR) is a novel target for therapy in subsets of non-small cell lung cancer, especially adenocarcinoma. Tumors with EGFR mutations showed good response to EGFR tyrosine kinase inhibitors (TKIs). We aimed to identify the discriminating capacity of immunohistochemical (IHC) scoring to detect L858R and E746-A750 deletion mutation in lung adenocarcinoma patients and predict EGFR TKIs response. Patients with surgically resected lung adenocarcinoma were enrolled. EGFR mutation status was genotyped by PCR and direct sequencing. Mutation-specific antibodies for L858R and E746-A750 deletion were used for IHC staining. Receiver operating characteristic (ROC) curves were used to determine the capacity of IHC, including intensity and/or quickscore (Q score), in differentiating L858R and E746-A750 deletion. We enrolled 143 patients during September 2000 to May 2009. Logistic-regression-model-based scoring containing both L858R Q score and total EGFR expression Q score was able to obtain a maximal area under the curve (AUC: 0.891) to differentiate the patients with L858R. Predictive model based on IHC Q score of E746-A750 deletion and IHC intensity of total EGFR expression reached an AUC of 0.969. The predictive model of L858R had a significantly higher AUC than L858R intensity only (p = 0.036). Of the six patients harboring complex EGFR mutations with classical mutation patterns, five had positive IHC staining. For EGFR TKI treated cancer recurrence patients, those with positive mutation-specific antibody IHC staining had better EGFR TKI response (p = 0.008) and longer progression-free survival (p = 0.012) than those without. In conclusion, total EGFR expression should be included in the IHC interpretation of L858R. After adjusting for total EGFR expression, the scoring method decreased the false positive rate and increased diagnostic power. According to the scoring method, the IHC method is useful to predict the clinical outcome and refine personalized therapy.
Genomic sequencing and analyses of Lymantria xylina multiple nucleopolyhedrovirus
Yu-Shin Nai, Chih-Yu Wu, Tai-Chuan Wang, Yun-Ru Chen, Wei-Hong Lau, Chu-Fang Lo, Meng-Feng Tsai, Chung-Hsiung Wang
BMC Genomics , 2010, DOI: 10.1186/1471-2164-11-116
Abstract: The genome of LyxyMNPV consists of 156,344 bases, has a G+C content of 53.4% and contains 157 putative open reading frames (ORFs). The gene content and gene order of LyxyMNPV were similar to those of LdMNPV, with 151 ORFs identified as homologous to those reported in the LdMNPV genome. Two genes (Lyxy49 and Lyxy123) were homologous to other baculoviruses, and four unique LyxyMNPV ORFs (Lyxy11, Lyxy19, Lyxy130 and Lyxy131) were identified in the LyxyMNPV genome, including a gag-like gene that was not reported in baculoviruses. LdMNPV contains 23 ORFs that are absent in LyxyMNPV. Readily identifiable homologues of the gene host range factor-1 (hrf-1), which appears to be involved in the susceptibility of L. dispar to NPV infection, were not present in LyxyMNPV. Additionally, two putative odv-e27 homologues were identified in LyxyMNPV. The LyxyMNPV genome encoded 14 bro genes compared with 16 in LdMNPV, which occupied more than 8% of the LyxyMNPV genome. Thirteen homologous regions (hrs) were identified containing 48 repeated sequences composed of 30-bp imperfect palindromes. However, they differed in the relative positions, number of repeats and orientation in the genome compared to LdMNPV.The gene parity plot analysis, percent identity of the gene homologues and a phylogenetic analysis suggested that LyxyMNPV is a Group II NPV that is most closely related to LdMNPV but with a highly distinct genomic organisation.Baculoviruses (family Baculoviridae) consist of rod-shaped, arthropod-specific viruses with double-stranded, circular DNA genomes ranging from 80 to 180 kb and enveloped nucleocapsids [1]. The occluded form of the virus is embedded in proteinaceous occlusion bodies (OBs) [1]. Baculoviridae is subdivided into four genera, Alphabaculovirus (lepidopteran-specific nucleopolyhedrovirus, NPV), Betabaculovirus (lepidopteran-specific granulovirus), Gammabaculovirus (hymenopteran-specific NPV) and Deltabaculovirus (dipteran-specific NPV) [2]. The lepidopteran-specific
A Study on Product Association Modeling in Collaborative Product Design
Yu-Min Chiang,Meng-Feng Huang
International Journal of Electronic Business Management , 2004,
Abstract: Many customers are no longer satisfied with mass-produced products; they are demanding customization and rapid delivery of innovative products. A new category of software, Collaborative Product Design (CPD), uses Internet technology to deliver product innovation at Internet speed and tie together product design, engineering, marketing, and customers into a global knowledge net. CPD enables organizations to quickly respond to the market change, so it has become increasingly important. Though CPD permits manufactures to significantly improve the core processes of the complete product life cycle, its information system will store a large number of product data in database day by day. R&D engineers are difficult to retrieve useful design data to cope with customers’ demand. Therefore, the purpose of this research is to apply the association rule that belongs to one of the data mining techniques to analyze the product feature association. This research also applies object-oriented technique of Unified Modeling Language, (UML) to establish a reference model integrated with CPD product feature association rules. In the end, this research cites an example of cellular phone model design and applies association rule technique to analyze product feature association rule of cellular phones. The results help cellular phone developers designing good products to conform to customers’ different demands.
A ROI Focusing Mechanism for Digital Cameras
Chu-Hui Lee,Meng-Feng Lin,Chun-Ming Huang,Chun-Wei Hsu
Lecture Notes in Engineering and Computer Science , 2011,
Abstract:
A Type II First Branchial Cleft Cyst Masquerading as An Infected Parotid Warthin’s Tumor
Meng-Feng Chen,Shir-Hwa Ueng,Shih-Ming Jung,Yao-Liang Chen
Chang Gung Medical Journal , 2006,
Abstract: The diagnosis of a parotid mass usually depends on thorough history taking and physicalexamination. Diagnostic modalities, including ultrasonographic examinations, computedtomography and magnetic resonance images, may also provide substantial information buttheir accuracy for diagnosis is sometimes questionable, especially in differentiating somerare neoplasms. First branchial cleft cysts (FBCCs) are rare causes of parotid swelling andcomprise less than 1% of all branchial anomalies. They are frequently misdiagnosed due totheir rarity and unfamiliar clinical signs and symptoms. We present a case of type II FBCCmasquerading as an infected parotid Warthin’s tumor. We also review the clinical signs andsymptoms of FBCCs in order to remind clinicians that this rare branchial anomaly canmimic an infected Warthin’s tumor and may be seated in the deep lobe of the parotid gland.By making an accurate pre-operative diagnosis of type II FBCC, we can minimize surgicalmorbidity and avoid incomplete resection and possible recurrence.
Surveillance and Genome Analysis of Human Bocavirus in Patients with Respiratory Infection in Guangzhou, China
Lin Xu,Xia He,Ding-mei Zhang,Fa-shen Feng,Zhu Wang,Lin-lin Guan,Jue-heng Wu,Rong Zhou,Bo-jian Zheng,Kwok-yung Yuen,Meng-feng Li,Kai-yuan Cao
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0044876
Abstract: Human bocavirus (HBoV) is a novel parvovirus associated with respiratory tract diseases and gastrointestinal illness in adult and pediatric patients throughout the world. To investigate the epidemiological and genetic variation of HBoV in Guangzhou, South China, we screened 3460 throat swab samples from 1686 children and 1774 adults with acute respiratory infection symptoms for HBoV between March 2010 and February 2011, and analyzed the complete genome sequence of 2 HBoV strains. Specimens were screened for HBoV by real-time PCR and other 6 common respiratory viruses by RT-PCR or PCR. HBoV was detected in 58 (1.68%) out of 3460 samples, mostly from pediatric patients (52/58) and inpatient children (47/58). Six adult patients were detected as HBoV positive and 5 were emergency cases. Of these HBoV positive cases, 19 (32.76%) had co-pathogens including influenza virus (n = 5), RSV (n = 5), parainfluenza (n = 4), adenovirus (n = 1), coronavirus (n = 7). The complete genome sequences of 2 HBoVs strains (Genbank no. JN794565 and JN794566) were analyzed. Phylogenetic analysis showed that the 2 HBoV strains were HBoV1, and were most genetically close to ST2 (GenBank accession number DQ0000496). Recombination analysis confirmed that HBoV strain GZ9081 was an intra–genotype recombinant strain among HBoV1 variants.
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