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Search Results: 1 - 10 of 200 matches for " Troels Kolding "
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QoS Self-Provisioning and Interference Management for Co-Channel Deployed 3G Femtocells
Troels Kolding,Pawel Ochal,Niels Terp Kjeldgaard J?rgensen,Klaus Pedersen
Future Internet , 2013, DOI: 10.3390/fi5020168
Abstract: A highly efficient self-provisioning interference management scheme is derived for 3G Home Node-Bs (HNB). The proposed scheme comprises self-adjustment of the HNB transmission parameters to meet the targeted QoS (quality of service) requirements in terms of downlink and uplink guaranteed minimum throughput and coverage. This objective is achieved by means of an autonomous HNB solution, where the transmit power of pilot and data are adjusted separately, while also controlling the uplink interference pollution towards the macro-layer. The proposed scheme is evaluated by means of extensive system level simulations and the results show significant performance improvements in terms of user throughput outage probability, power efficiency, femtocell coverage, and impact on macro-layer performance as compared to prior art baseline techniques. The paper is concluded by also showing corresponding measurements from live 3G high-speed packet access (HSPA) HNB field-trials, confirming the validity of major simulation results and assumptions.
Sharing Information: Report on the LIBER Library Security Network (LSN) Since 2002
Erland Kolding Nielsen
Liber Quarterly : The Journal of European Research Libraries , 2008,
Abstract: On 2 July 2002, the Executive Board of LIBER, in line with the Copenhagen Principles of 14 May 2002, endorsed the establishment of a Library Security Network to facilitate the exchange of confidential security information among European national, university and other important research libraries with valuable collections. The Network came into being at the end of 2002. It has now been running for more than five years. The objective was, and is, to create a safe information and communication network, based on e-mail, for European library directors and security managers. This paper aims to review the experience: Has the system worked? Has it helped in terms of preventing crime, in solving crimes, in raising security awareness among the member institutions? Furthermore, the aim is to contribute to a revision in the broader perspective of a European context: Is it enough? Should it work otherwise? Are there other channels of information? Should the Network be expanded?
Library Security Management: An Introduction
Erland Kolding Nielsen
Liber Quarterly : The Journal of European Research Libraries , 2002,
Abstract: During the last week of January 2001, the Royal Library suffered serious thefts in both its special reading rooms for maps and for manuscripts and rare books. Precious maps were removed from folio editions and smuggled out by a thief who was something of a magician. For years the Royal Library has been one of the most effectively secured buildings housing cultural assets in Denmark. Nevertheless, this incident happened and apparently could happen. The thefts were discovered the same day, but the thief had become suspicious and did not reappear over the next few days as expected. However, because the theft had been filmed on security cameras in the reading room, we had very good photographs of the thief. After days of hard work we were able to discover from the security film how the theft had been carried out and how the items had been smuggled out of the reading room. On the second day after the incident, I warned my fellow directors in the Nordic national libraries and in a number of university libraries with historical collections. Nevertheless, the following week the thief or his accomplice visited Helsinki University Library, and later we discovered that they had been in the Royal Library in The Hague at almost the same time, as well as some months earlier, and in the Royal Library in Stockholm on numerous occasions from the autumn of 2000 onwards.
Digitisation of Library Material in Europe: Problems, Obstacles and Perspectives anno 2007
Erland Kolding Nielsen
Liber Quarterly : The Journal of European Research Libraries , 2008,
Abstract: This paper is a short introductory policy paper about the state-of-the-art of digitisation of library material in Europe, seen from the chief executive point of view of a big national and university library in the autumn of 2007. It focuses on current problems, obstacles, and some perspectives. What has been achieved, what are the problems and obstacles in terms of especially mass digitisation in the light of the so-called Google challenge and the response by the Commission of the European Union, and what are the consequences likely to be?
A Vision for Liber's Strategy 2003-2006
Erland Kolding Nielsen
Liber Quarterly : The Journal of European Research Libraries , 2003,
Abstract:
Tocilizumab: The evidence for its place in the treatment of juvenile idiopathic arthritis
Troels Herlin
Core Evidence , 2009, DOI: http://dx.doi.org/10.2147/CE.S5992
Abstract: cilizumab: The evidence for its place in the treatment of juvenile idiopathic arthritis Review (4378) Total Article Views Authors: Troels Herlin Published Date August 2009 Volume 2009:4 Pages 181 - 189 DOI: http://dx.doi.org/10.2147/CE.S5992 Troels Herlin Department of Pediatrics, Aarhus University Hospital, Skejby, Aarhus, Denmark Introduction: Juvenile idiopathic arthritis (JIA) is one of the most common chronic diseases with childhood onset. It comprises different subtypes of which the systemic onset subtype is often resistant to treatment. With the advent of biological treatment with tumor necrosis factor-α (TNFα)-inhibitors, the clinical outcome of JIA has improved considerably, but only for subtypes other than systemic JIA. Substantial evidence shows that the proinflammatory cytokine interleukin-6 (IL-6) plays a pivotal role in systemic JIA. The blockage of IL-6 action by tocilizumab, a humanized anti-IL-6-receptor monoclonal antibody, could therefore be an effective treatment of systemic JIA. Aims: The purpose of this article was to review the clinical trials of tocilizumab and to discuss its place in the treatment of JIA with the focus on the systemic onset of disease. Evidence review: Two phase II studies and one phase III clinical trial of tocilizumab demonstrating the clinical efficacy and safety in systemic onset JIA have been published. Within those studies, sustained and high response rates of clinical improvement have been achieved with American College of Rheumatology Pediatric criteria (ACRPed) 30, 50, and 70 observed in 98%, 94%, and 90% of patients, respectively, after 48 weeks. One study regarding the clinical efficacy of tocilizumab for the treatment of oligo- and polyarticular JIA has been presented only as a conference abstract. Place in therapy: The very promising results seen so far in patients with severe systemic JIA and acceptable tolerability gives tocilizumab a central role in the future therapy in controlling this disease. No other biological therapy has achieved similar high response rates when treating with tocilizumab 8 mg/kg every two weeks to patients with systemic onset JIA, but direct comparison of the efficacy of different biological agents are not yet available.
Scientific results from the deepened Lopra-1 borehole, Faroe Islands: Hydrocarbon gases in Palaeogene volcanic rocks from the Lopra-1/1A well, Faroe Islands
Laier, Troels
Geological Survey of Denmark and Greenland Bulletin , 2006,
Abstract: Hydrocarbon gases were monitored in the drilling fluid during deepening of the Lopra-1 well from 2178–3565 m, in which thermogenic, methane-rich gases had been found previously. The mud gas concentration, up to 105 ppm of methane, was generally higher in the hyaloclastite sequence, 2470 m – terminal depth (TD), than in the overlying lavas of the lower basalt formation. The highest concentrations of mud gas in the lower basalt formation were associated with the more porous tuffaceous zones, whereas no simple relationship could be established between measured mud gas concentrations and porosity of the hyaloclastic rocks, which showed less marked porosity variations than the lavas.Chemical (C2+ < 1%) and isotopic (δ13C1: –34 to –39‰) compositions of seven samples of mud gas collected at peak gas concentrations between 2657 m and 3442 m compare well with those of the hydrocarbon gases which had been seeping more or less continuously into the existing well since 1983, suggesting a common origin of the gases. Headspace methane concentrations measured in 135 canned samples of cuttings were scattered between 10 ppm and 6 × 103 ppm, with the exception of six samples from a short interval, 2685–2745 m, which showed consistently high values > 104 ppm. No particularly gas-rich zones were indicated, however, by the mud gas, nor was any significant change in lithology noted for this interval. It is possible that the technique of turbo-drilling, that had been attempted over a short interval, 2657–2675 m prior to collection of the high-level methane samples, may have caused enhanced degassingdue to the very fine cuttings produced. Chemical and isotopic composition of headspace gas and mud gas indicated the same type of gas throughout the well, although headspace methane tended to bemore enriched with respect to the 13C isotope.The origin of the Lopra-1 gas is discussed in the light of recent information obtained from source rock studies of central East Greenland and the Faroe–Shetland Basin.
Tocilizumab: The evidence for its place in the treatment of juvenile idiopathic arthritis
Troels Herlin
Core Evidence , 2009,
Abstract: Troels HerlinDepartment of Pediatrics, Aarhus University Hospital, Skejby, Aarhus, DenmarkIntroduction: Juvenile idiopathic arthritis (JIA) is one of the most common chronic diseases with childhood onset. It comprises different subtypes of which the systemic onset subtype is often resistant to treatment. With the advent of biological treatment with tumor necrosis factor-α (TNFα)-inhibitors, the clinical outcome of JIA has improved considerably, but only for subtypes other than systemic JIA. Substantial evidence shows that the proinflammatory cytokine interleukin-6 (IL-6) plays a pivotal role in systemic JIA. The blockage of IL-6 action by tocilizumab, a humanized anti-IL-6-receptor monoclonal antibody, could therefore be an effective treatment of systemic JIA.Aims: The purpose of this article was to review the clinical trials of tocilizumab and to discuss its place in the treatment of JIA with the focus on the systemic onset of disease. Evidence review: Two phase II studies and one phase III clinical trial of tocilizumab demonstrating the clinical efficacy and safety in systemic onset JIA have been published. Within those studies, sustained and high response rates of clinical improvement have been achieved with American College of Rheumatology Pediatric criteria (ACRPed) 30, 50, and 70 observed in 98%, 94%, and 90% of patients, respectively, after 48 weeks. One study regarding the clinical efficacy of tocilizumab for the treatment of oligo- and polyarticular JIA has been presented only as a conference abstract.Place in therapy: The very promising results seen so far in patients with severe systemic JIA and acceptable tolerability gives tocilizumab a central role in the future therapy in controlling this disease. No other biological therapy has achieved similar high response rates when treating with tocilizumab 8 mg/kg every two weeks to patients with systemic onset JIA, but direct comparison of the efficacy of different biological agents are not yet available.Keywords: tocilizumab, anti-IL-6-receptor antibody, biologics, systemic, juvenile idiopathic arthritis
Domain Structure of Black Hole Space-Times
Troels Harmark
Physics , 2009, DOI: 10.1103/PhysRevD.80.024019
Abstract: We introduce the domain structure for stationary black hole space-times. Given a set of commuting Killing vector fields of the space-time the domain structure lives on the submanifold where at least one of the Killing vector fields have zero norm. Depending on which Killing vector field has zero norm the submanifold is naturally divided into domains. A domain corresponds either to a set of fixed points of a spatial symmetry or to a Killing horizon, depending on whether the characterizing Killing vector field is space-like or time-like near the domain. The domain structure provides invariants of the space-time, both topological and geometrical. It is defined for any space-time dimension and any number of commuting Killing vector fields. We examine the domain structure for asymptotically flat space-times and find a canonical form for the metric of such space-times. The domain structure generalizes the rod structure introduced for space-times with D-2 commuting Killing vector fields. We analyze in detail the domain structure for Minkowski space, the Schwarzschild-Tangherlini black hole and the Myers-Perry black hole in six and seven dimensions. Finally we consider the possible domain structures for asymptotically flat black holes in six and seven dimensions.
Supergravity and Space-Time Non-Commutative Open String Theory
Troels Harmark
Physics , 2000, DOI: 10.1088/1126-6708/2000/07/043
Abstract: We study the non-critical space-time non-commutative open string (NCOS) theory using a dual supergravity description in terms of a certain near-horizon limit of the F1-Dp bound state. We find the thermodynamics of NCOS theory from supergravity. The thermodynamics is equivalent to Yang-Mills theory on a commutative space-time. We argue that this fact does not have to be in contradiction with the expected Hagedorn behaviour of NCOS theory. To support this we consider string corrections to the thermodynamics. We also discuss the relation to Little String Theory in 6 dimensions.
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