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Search Results: 1 - 10 of 569 matches for " Tristan Galbas "
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Cell-type specific regulation of MARCH1 E3 ubiquitin ligase by the anti-inflammatory cytokine IL-10  [PDF]
Tristan Galbas, Jacques Thibodeau
Open Journal of Immunology (OJI) , 2012, DOI: 10.4236/oji.2012.24020
Abstract: Membrane-associated RING-CH-1 (MARCH1) is an E3 ubiquitin ligase which targets MHC-II, CD86 and various other molecules for degradation. It is one of the most efficient post-translational regulators of antigen presentation. MARCH1 is expressed in resting immature dendritic cells and B cells but can be induced in other cell types. While activation of most immune cells results in a reduction in MARCH1 gene expression, its anti-inflammatory properties are highlighted by its induction in response to IL-10. Here, we review what is known about the regulation of MARCH1 gene expression in response to IL-10 by various immune cells. We speculate on the role of MARCH1 ininfection, its differential expression pattern and the promise that this E3 ubiquitin ligase holds to influence immune responses and mitigate immune pathologies.
Impact of Globulins Derived from Genetically Modified and Conventional Soybean on Swine Lymphocyte Proliferation in in vitro Cultures
Mariola Galbas , Kamila Borys , Anna Wo niak , Marek Selwet
Annals of Animal Science , 2011, DOI: 10.2478/v10220-011-0002-2
Abstract: The majority of the global feed market is dominated by the Roundup Ready 40-3-2 transgenic soybean varieties developed and marketed by Monsanto Company, which are characterized by tolerance to glyphosate, the active ingredient of the Roundup herbicide. It should be remembered, however, that soybean is one of the major allergens which may affect animal health. The aim of the study was to compare allergenic properties of globulins derived from genetically modified (GM) soybean imported from the USA and conventional soybean developed in Poland. Analyses were performed by measuring porcine lymphocyte proliferation in in vitro cultures. It turned out that both genetically modified and conventional soybean proteins caused immune response at the level of negative control. A slight increase in relation to the negative control was observed in the case of 7S and 11S fractions derived from the GM meal and 7S fraction isolated from Nawiko meal.
Risk Aggregation by Using Copulas in Internal Models  [PDF]
Tristan Nguyen, Robert Danilo Molinari
Journal of Mathematical Finance (JMF) , 2011, DOI: 10.4236/jmf.2011.13007
Abstract: According to the Solvency II directive the Solvency Capital Requirement (SCR) corresponds to the economic capital needed to limit the probability of ruin to 0.5%. This implies that (re-)insurance undertakings will have to identify their overall loss distributions. The standard approach of the mentioned Solvency II directive proposes the use of a correlation matrix for the aggregation of the single so-called risk modules respectively sub-modules. In our paper we will analyze the method of risk aggregation via the proposed application of correlations. We will find serious weaknesses, particularly concerning the recognition of extreme events, e. g. natural disasters, terrorist attacks etc. Even though the concept of copulas is not explicitly mentioned in the directive, there is still a possibility of applying it. It is clear that modeling dependencies with copulas would incur significant costs for smaller companies that might outbalance the resulting more precise picture of the risk situation of the insurer. However, incentives for those companies who use copulas, e. g. reduced solvency capital requirements compared to those who do not use it, could push the deployment of copulas in risk modeling in general.
Implications of an Aging Population on Pension Systems and Financial Markets  [PDF]
Tristan Nguyen, Ralf Stüzle
Theoretical Economics Letters (TEL) , 2012, DOI: 10.4236/tel.2012.22026
Abstract: In this paper, we introduce a macroeconomic model of overlapping generations to analyze the impacts of the demographic changes as well as the interactions between pension system, bond and stock markets. Furthermore, we examine how the pension system influences the distribution of wealth, consumption and saving within generations. In the context of this model, we show a drastic decline of capital market returns due to an aging population. Moreover, we examine the impacts demographic changes can have on individuals’ welfare for an existing pay-as-you-go pension scheme. Raising the pensionable age combined with a decrease of the contributions seems to be the best policy. On the other hand, increases in contributions as a result of demographic changes show the highest welfare losses. Taken into account the recent pension reforms in Germany, raising the retirement age or a faster transition from a pay-as-you-go pension system to a capital funded one would make sense. But it is questionable whether such a policy will be enforceable with an aging electorate.
El feto agresivo: Parto, formación de la persona y mito-historia en los Andes
Estudios atacame?os , 2002, DOI: 10.4067/S0718-10432002002200008
Abstract: on the basis of an ethnographic and linguistic study of maternal mortality in bolivia, this ethno_obstetric research deals with conception, gestation and childbirth in a quechua_speaking community near potosí. it analyzes the parallelism established between the early formation of the person and the mytho_historical origins of society. prehispanic pagan substance flows constantly into a society of "converts" (conversos), thereby giving reality to the juridical concept of the "originary indian" (indio originario). the article aims to transcend the opposition between "essentialist" and "hybridist" interpretations of indian society by showing that the originario is necessarily constructed by indian commoners as "essential" without therefore denying his/her constant historical transformation. the rites of separation of the "aggressive foetus" from the mother also pose questions to psychoanalysts concerning the influence that perinatal experiences can have on the formation of the individual person in different historical and cultural contexts.
Chungará (Arica) , 2010, DOI: 10.4067/S0717-73562010000100037
Abstract: the article relates john murra's theory of the "vertical archipelago" -a dynamic model of the changing historical relations between andean societies, the complementary ecologies they inhabit, and emergent "state"-formations to transformationalist theories developed particularly among amazonian peoples. drawing on field-work with a longlived "archipelago" in the valleys of the macha ayllu (northern potosí, bolivia), the author shows the conflictive experience of valley "islands", which must invert their moiety (saya) affiliations to survive pressures from the larger groups in which they are implanted. the confusion of levels of segmentation and the "island" formation produces different valley alliances from those sought on the puna, while presupposing a shared horizon of ideas concerning violence. andean warfare is characterized by the same ?ontological instability " at the blurred frontier between humans and animals that is found among other amerindian groups, and elsewhere in the world. different kinds of shapeshifting during fiestas and warfare, and the reformulation of animal-human frontiers, are seen to be related to different social and historical contexts.
From transcendental to practical intersubjectivity: a social psychological approach to Kant's musical aesthetics
Torriani, Tristan;
Trans/Form/A??o , 2010, DOI: 10.1590/S0101-31732010000100007
Abstract: it is well known that kant’s aesthetics is framed intersubjectively because he upholds the claim of taste to universality. however, the transcendental foundation of this shared universality is a supersensible ground which is taken for granted but which cannot be brought directly into communicative experience. kant’s reliance on the synthetic a priori structure of aesthetic judgment also removes it from the sphere of observable personal interaction. this argumentative strategy exposes it to skeptical challenge and generates inaccessible references to inner representations (be they intuitions, categories of the understanding or rational ideas). it is not sufficient, as kant did, to propose a description of aesthetic experience that is subjectively plausible and thereby claim its intersubjective validity. it is indispensable to embody intersubjectivity in behavior and language. in practical intersubjectivity, aesthetic attitudes are dealt with in a concrete and accessible manner without relying on mentalistic assumptions as a foundation. conceptual terms such as 'agreeable’, 'beauty’, 'sublime’, 'ugly’, 'universality’ acquire new meaning in a conversational context and aesthetic claims are tested in a dialogical game semantics model.
Gr slund, B., Knutsson, K., Knutsson, H., Taffinder, J. & Stina, E. (eds). 1990. The Interpretative Possibilities of Microwear Studies
Tristan Carter
Papers from the Institute of Archaeology , 1991, DOI: 10.5334/pia.9
Self-Ownership, World-Ownership, and Initial Acquisition
Tristan Rogers
Libertarian Papers , 2010,
Abstract: G.A. Cohen was perhaps libertarianism’s most formidable critic. In Self-Ownership, Freedom, and Equality he levels several strong criticisms against Robert Nozick’s theory put forth in Anarchy, State, and Utopia. In this paper, I counter several of Cohen’s criticisms. The debate operates at three stages: (1) self-ownership, (2) world-ownership, and (3) initial acquisition. At the first stage, Cohen does not attempt to refute self-ownership, but weaken its force in providing moral grounds for capitalism. Here I argue that Cohen’s attempt to overturn Nozick’s slavery argument is unsuccessful because partial-slavery, while normatively different from full-slavery, is still normatively wrong. At the second stage, Cohen argues for a joint-ownership view of the world’s resources. In particular, he claims that self-ownership is rendered merely formal in a jointly-owned world and in a capitalist world. To rebut this challenge I show that even if Cohen is right about this, libertarian self-ownership is only formal in Cohen’s peculiar case where only two people exist and one owns everything. In contrast, self-ownership in a jointly-owned world is formal in all cases. Lastly, at the third stage, Cohen argues against Nozick’s interpretation of the Lockean proviso, claiming that it is impossible to satisfy. Granting Cohen’s argument here, I go on to defend Jan Narveson’s no-proviso view of acquisition from Cohen’s thus far unanswered criticism. I show that significantly, in his critique, Cohen equivocates between positive and negative rights. Taken jointly, my responses at these three stages ground the anti-egalitarian conclusion that, in Cohen’s words, ‘[e]xtensive inequality of condition is unavoidable, or avoidable only on pain of violating people’s rights to themselves and to things.’ The sequence, then, is from self-ownership, to world-ownership, via initial acquisition.
Living In and Out of the Host Society. Aspects of Nepalese Migrants' Experience of Division in Qatar Viviendo dentro y fuera de la sociedad receptora. Aspectos de la experiencia de los inmigrantes nepaleses de Qatar Leben innerhalb und au erhalb eines Aufnahmelandes. Abgrenzungserleben nepalesischer Migranten und Migrantinnen in Katar
Tristan Bruslé
Forum : Qualitative Social Research , 2010,
Abstract: This article examines the place that Nepalese immigrant workers occupy in Qatar, a country where migrants' social and spatial positions are determined by their nationality and qualifications. The article uses visual images, mainly photographs, to illustrate the divided nature of society in Qatar. While trying to adopt the migrants' point of view, the author spent time both in the place where they live, that is the labor camps, and in central Doha where migrants spend their free time. Thus, except for the work place, pictures were taken both in private and public spaces to outline migrants' living spaces. They illustrate the strong constraints migrants have to face in everyday life. For the author himself, pictures are a means of taking a closer look at these places, once back from a field trip. By playing with different scales, zooming from the labor camp setting to the details of how rooms are arranged, pictures enable us to grasp the multiple facets of segregation and the way Nepalese migrant workers draw on their own resources to make foreign places their own. However, the adjustments made to these living spaces continue to reflect their lowly position in a highly segmented society. URN: urn:nbn:de:0114-fqs1002319 Este artículo examina el lugar que ocupan los trabajadores nepaleses inmigrantes en Qatar, un país donde las posiciones sociales y espaciales de los inmigrantes están determinadas por su nacionalidad y capacitación. El artículo utiliza imágenes visuales, principalmente fotografías, para ilustrar la naturaleza dividida de la sociedad en Qatar. Mientras intenta adoptar el punto de vista de los inmigrantes, el autor pasa tiempo tanto en el lugar en donde viven, que son los campos de trabajo y en Doha central donde los inmigrantes pasan su tiempo libre. Así, a excepción del lugar de trabajo, las imágenes fueron tomadas en espacios públicos y privados para delinear los espacios donde viven los inmigrantes. Ellas ilustran la fuerte restricción que los inmigrantes tienen que soportar en la vida diaria. Para el autor mismo, las imágenes son los medios de echar un vistazo más cercano a estos lugares, una vez que se regresa del viaje de campo. Jugando con diversas escalas, enfocando desde el campo de trabajo a los detalles de cómo se arreglan los cuartos, las imágenes nos permiten capturar las múltiples facetas de la segregación y la manera en que los trabajadores inmigrantes nepaleses trazan con sus propios recursos los lugares extranjeros para hacerlos propios. Sin embargo, los ajustes hechos a los espacios en donde viven siguen reflejando su precar
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