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Search Results: 1 - 10 of 4770 matches for " Tomohiro Suzuki "
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Supercapacitor Consisting of a Form Core Sandwich with Woven Carbon Fiber Skin  [PDF]
Akira Todoroki, Tomohiro Sawada, Yoshihiro Mizutani, Yoshiro Suzuki
Open Journal of Composite Materials (OJCM) , 2015, DOI: 10.4236/ojcm.2015.54013
Abstract: Structural capacitors are composite structures that function as energy storage capacitors. Parallel plate-type capacitors have the advantage of high voltage resistance, but are limited by low capacitance. An electric double-layer capacitor with a composite structure using a solid polymer electrolyte matrix with a glass fiber fabric separator has recently been developed. However, the solid polymer electrolyte caused the capacitor to possess high internal resistance. In the present study, a new design of supercapacitor using a form core sandwich with high water retention is proposed and experimentally investigated. Activated carbon sheets are used as electrodes on the form core sandwich to make a supercapacitor. Woven carbon fabric is used as lead wires of the supercapacitor. The resulting supercapacitor displays a low surface resistance of 810 Ωcm2 and high areal capacitance of 520 mF/cm2.
Oscillating Mechanical Stimulation of the Craniocervical Region as Physical Therapy for Chronic Migraine: A Pilot Trial  [PDF]
Makoto Shiraishi, Munefumi Hotta, Tomohiro Suzuki, Noboru Imai
International Journal of Clinical Medicine (IJCM) , 2019, DOI: 10.4236/ijcm.2019.103015
Abstract: Objective: We conducted a prospective trial of oscillating mechanical stimulation (OS) of the craniocervical region as treatment for drug-refractory chronic migraine (CM). Methods: Ten patients (8 women, 2 men; mean age 47.0 ± 15.1 years) were enrolled. The treatment was administered over an 8-week period to 13, 4, and 9 sites on the face and head, neck, and upper back, respectively, at 5- to 15-pound intensity. The primary outcome measure was the number of days patients suffered a migraine (hereafter “number of migraine days”), and the secondary outcome measures were the six-item Headache Impact Test (HIT-6) and Visual Analog Scale (VAS) scores for migraine pain intensity and the nine-item Patient Health Questionnaire (PHQ-9) and the seven-item Generalized Anxiety Disorder (GAD-7) scale scores. Results: Nine patients completed treatment. The number of migraine days remained unchanged, from a mean 21.7 ± 11.6 days/month before treatment to 19.3 ± 7.3 days/month upon completion of treatment. However, the HIT-6 scores improved from 67.0 ± 8.2 to 61.4 ± 7.1 (p = 0.007) after 3 weeks, 61.1 ± 11.5 (p = 0.01) after 6 weeks, and 59.9 ± 11.6 (p = 0.035) upon completion of treatment. Similarly, the VAS scores improved significantly from 7.3 ± 1.7 to 5.7 ± 3.1 (p = 0.018) at 6 weeks and 4.8 ± 2.8 (p = 0.011) upon completion of treatment. The GAD-7, PHQ-9, and allodynia scale scores remained unchanged. Conclusion: Our data suggest that OS is well tolerated and may become a feasible form of treatment for drug-resistant CM.
Small Urban Greenery: Mapping and Visual Analysis in Kyōjima-sanchōme
Jorge Almazán,Darko Radovic,Tomohiro Suzuki
Archnet-IJAR : International Journal of Architectural Research , 2012,
Isolated Metastatic Barrett’s Adenocarcinoma of the Thoracic Epidural Space Causing Paraplegia  [PDF]
Tomohiro Banno, Tsuyoshi Ohishi, Daisuke Suzuki, Kazufumi Yamamoto, Hiroki Ushirozako, Sho Kobayashi, Yukihiro Matsuyama
Open Journal of Orthopedics (OJO) , 2013, DOI: 10.4236/ojo.2013.31001

Barrett’s adenocarcinoma is an esophageal cancer arising from Barrett’s esophagus. In this report, a metastatic epidural tumor from Barrett’s adenocarcinoma with paraplegia that required surgical treatment is documented. A 50-year-old man who had had a resection of the distal esophagus due to Barrett’s adenocarcinoma six month before presented with progressive weakness and numbness in lower limbs with urinary disturbance. Magnetic resonance imaging of the thoracic region revealed compression of the spinal cord at the T3-4 level by a dorsally located epidural mass. No signal changes were detected in vertebrae. Since the paraplegia and urinary disturbance were rapidly progressing, laminectomy and tumor resection was performed. Postoperatively, neurological function improved immediately and there was no recurrence of spinal region. This is the first report on an isolated metastatic Barrett’s adenocarcinoma of the thoracic epidural space.

Continuous Saccharification of Laminarin by Immobilized Laminarinase ULam111 Followed by Ethanol Fermentation with a Marine-Derived Yeast  [PDF]
Daisuke Mitsuya, Masashi Yamamoto, Masahiko Okai, Akira Inoue, Tomohiro Suzuki, Takao Ojima, Naoto Urano
Advances in Microbiology (AiM) , 2017, DOI: 10.4236/aim.2017.75032
Abstract: We isolated a novel laminarinase ULam111 from Flavobacterium sp. strain UMI-01. Purified ULam111 showed degradation activity against laminarin with the specific activity of 224 ± 18 U/mg at 30°C and pH 6.0. Its optimum temperature was 50°C, and degradation activities against laminarin were observed at 4°C - 80°C. With a laminarin degradation system, we investigated the preparation and properties of immobilized ULam111 with the use of the 11 types of carriers. The high activity recoveries of immobilized ULam111 were as follows: 19.4% for IB-S60P carrier beads (the non-ionic type), 15.6% for IB-S60S carrier beads (the non-ionic type), 11.9% for IB-150P carrier beads (the covalent type), and 7.1% for IB-C435 carrier beads (the cationic type). With the repeated use of immobilized ULam111, the enzyme activities immobilized on IB-S60S and those on IB-S60P remained at 40% and 30% respectively after the sixth trial. We selected IB-S60S as suitable beads for enzyme immobilization, and we attempted to construct a reactor system with ULam111 immobilized on IB-S60S beads. In this system, 1.2 - 1.9 g/L glucose was repeatedly produced from 30 mg/mL laminarin solutions after 20 hr when the reactor operation was repeated 10 times. We examined ethanol fermentation from the saccharified solutions with a marine-derived yeast (Saccharomyces cerevisiae C-19), and 0.51 - 0.58 g/L bioethanol was produced from the saccharified solution that contained 1.71 - 1.86 g/L of glucose.
Early-Onset Chronic Inflammatory Disease Associated with Maternal Microchimerism
Tomoaki Ishikawa,Yoshihiko Sakurai,Tomohiro Takeda,Hiroshi Suzuki
Case Reports in Pediatrics , 2012, DOI: 10.1155/2012/323681
Abstract: Maternal microchimerism (mMc) refers to the presence of a small population of cells originating from the mother. Whether mMc leads to autoimmune responses in children remains controversial. We describe here an 11-year-old boy with persistent fever and elevated levels of C-reactive protein from infancy onward. During infancy, the patient presented with high fever, skin rashes, and hepatic dysfunction. Careful examination including a liver biopsy failed to reveal the cause. At 4 years old, petechiae developed associated with thrombocytopenia and positive anti-dsDNA autoantibodies. Steroid pulse therapy was effective, but the effect of low-dose prednisone was insufficient. At age 9, an extensive differential diagnosis was considered especially for infantile onset autoinflammatory disorders but failed to make a definitive diagnosis. On admission, the patient exhibited short stature, hepatosplenomegaly, generalized superficial lymphadenopathy, and rashes. Laboratory findings revealed anemia, elevated levels of inflammation markers, and hypergammaglobulinemia. Serum complement levels were normal. Serum levels of IL-6 and B-cell activating factor were elevated. Viral infections were not identified. Although HLA typing revealed no noninherited maternal antigens in lymphocytes, female cells were demonstrated in the patient’s skin and lymph nodes, suggesting that maternal microchimerism might be involved in the pathogenesis of fever without source in infants.
Arthroscopic treatment of a medial meniscal cyst using a posterior trans-septal approach: a case report
Tsuyoshi Ohishi, Eiji Torikai, Daisuke Suzuki, Tomohiro Banno, Yosuke Honda
Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology , 2010, DOI: 10.1186/1758-2555-2-25
Abstract: Recently, selective menisectomy followed by decompression of the cyst is commonly performed in arthroscopic treatment of a meniscal cyst [1-3]. However, the surface of the meniscus is intact in the case of a grade 2 meniscal tear judged by magnetic resonance imaging (MRI) [4]. An operator might hesitate to perform partial resection of an intact meniscus in communication with a cyst since meniscal function could be sacrificed. In this paper, a meniscal cyst arising from the posterior horn of the medial meniscus was resected under arthroscopy, without menisectomy, using a posterior trans-septal approach. This is the first report on resection of a meniscal cyst using an arthroscopic posterior trans-septal approach.A 59-year-old jobless man presented at our hospital with a 2-month history of transient right popliteal pain when standing after squatting and while descending stairs. He was 170 cm tall and 55 kg in body weight and had not suffered from any antecedent trauma. Clinical examination of the right knee revealed a full range of motion without catching and locking episode. No swelling, warmness, erythema, tenderness (including the medial joint line) or hydrops was found around the knee. There was no anterior, posterior or lateral instability. He did not have pain during manual instability tests. McMurray's test reproduced pain but no click at the medial joint line. No mass was palpable around the knee. Standard radiographs showed no sign of osteoarthritis. An MRI revealed a grade 2 horizontal tear according to Mink's classification of the posterior segment of the medial meniscus [4] (Fig 1-A). A multilobulated meniscal cyst arising from the posterior horn of the medial meniscus to the posterior septum just behind the posterior cruciate ligament (PCL) was also detected (Fig 1-B, C). Communication tracts between horizontal tear of the meniscus and the cyst were identified on the MRI coronal plane (Fig 1-D).Arthroscopic surgery was performed under spinal anesthesia wi
Classification of Oriental Melon by RAPD Analysis
Toshiyuki Matsui,Yusuke Kosugi,Tomohiro Yanagi,Haruo Suzuki
Pakistan Journal of Biological Sciences , 2002,
Abstract: The genetic relationship of 13 oriental melon (Cucumis melo L.) was determined using random amplified polymorphic DNA (RAPD) analysis with 12 dodecamer oligonucleotide primers. Representative cultivars could be divided into two major groups at 0.756 similarity value. One group included 7 makuwa melons namely, " Nara-1-gou ", " Tiger-melon ", " Kinpyou ", " Kiku-melon ", " Nashi-makuwa ", " Shouwa-melon " and 4 conomon melons namely, " Numame-shirouri ", " Katsura-ohoshirouri ", " Tokyo-ohoshirouri ", " Kuromonao-ohoshirouri ". The other major group included 2 makuwa cultivars namely " Ginsen " and " Wasegin ". The RAPD showed that conomon melon belonged to same species as makuwa melon. It seemed that, makuwa melon is an allogamous plant which hybridizes easily with table-melons and conomon melon and it might have hybridized with conomon melon in the distant past.
ChopSticks: High-resolution analysis of homozygous deletions by exploiting concordant read pairs
Yasuda Tomohiro,Suzuki Shin,Nagasaki Masao,Miyano Satoru
BMC Bioinformatics , 2012, DOI: 10.1186/1471-2105-13-279
Abstract: Background Structural variations (SVs) in genomes are commonly observed even in healthy individuals and play key roles in biological functions. To understand their functional impact or to infer molecular mechanisms of SVs, they have to be characterized with the maximum resolution. However, high-resolution analysis is a difficult task because it requires investigation of the complex structures involved in an enormous number of alignments of next-generation sequencing (NGS) reads and genome sequences that contain errors. Results We propose a new method called ChopSticks that improves the resolution of SV detection for homozygous deletions even when the depth of coverage is low. Conventional methods based on read pairs use only discordant pairs to localize the positions of deletions, where a discordant pair is a read pair whose alignment has an aberrant strand or distance. In contrast, our method exploits concordant reads as well. We theoretically proved that when the depth of coverage approaches zero or infinity, the expected resolution of our method is asymptotically equal to that of methods based only on discordant pairs under double coverage. To confirm the effectiveness of ChopSticks, we conducted computational experiments against both simulated NGS reads and real NGS sequences. The resolution of deletion calls by other methods was significantly improved, thus demonstrating the usefulness of ChopSticks. Conclusions ChopSticks can generate high-resolution deletion calls of homozygous deletions using information independent of other methods, and it is therefore useful to examine the functional impact of SVs or to infer SV generation mechanisms.
LORETA Current Source Density for Duration Mismatch Negativity and Neuropsychological Assessment in Early Schizophrenia
Tomohiro Miyanishi, Tomiki Sumiyoshi, Yuko Higuchi, Tomonori Seo, Michio Suzuki
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0061152
Abstract: Introduction Patients with schizophrenia elicit cognitive decline from the early phase of the illness. Mismatch negativity (MMN) has been shown to be associated with cognitive function. We investigated the current source density of duration mismatch negativity (dMMN), by using low-resolution brain electromagnetic tomography (LORETA), and neuropsychological performance in subjects with early schizophrenia. Methods Data were obtained from 20 patients meeting DSM-IV criteria for schizophrenia or schizophreniform disorder, and 20 healthy control (HC) subjects. An auditory odd-ball paradigm was used to measure dMMN. Neuropsychological performance was evaluated by the brief assessment of cognition in schizophrenia Japanese version (BACS-J). Results Patients showed smaller dMMN amplitudes than those in the HC subjects. LORETA current density for dMMN was significantly lower in patients compared to HC subjects, especially in the temporal lobes. dMMN current density in the frontal lobe was positively correlated with working memory performance in patients. Conclusions This is the first study to identify brain regions showing smaller dMMN current density in early schizophrenia. Further, poor working memory was associated with decreased dMMN current density in patients. These results are likely to help understand the neural basis for cognitive impairment of schizophrenia.
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