Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99


Any time

2015 ( 13 )

2014 ( 14 )

2013 ( 38 )

2012 ( 105 )

Custom range...

Search Results: 1 - 10 of 719 matches for " Tomislav Kosti? "
All listed articles are free for downloading (OA Articles)
Page 1 /719
Display every page Item
Comparative effect of streptokinase and alteplase on electrocardiogram and angiogram signs of myocardial reperfusion in ST segment elevation acute myocardial infarction
Toma?evi? Miloje,KostiTomislav,Apostolovi? Svetlana,Peri?i? Zoran
Srpski Arhiv za Celokupno Lekarstvo , 2008, DOI: 10.2298/sarh0810481t
Abstract: INTRODUCTION Modern pharmacological reperfusion in ST segment elevation acute myocardial infarction means the application of fibrin specific thrombolytics combined with modern antiplatelets therapy dual antiplateles therapy, acetylsalicylic acid and clopidogrel, and enoxaparin. The contribution of each agent has been widely examined in large clinical studies, but not sufficiently has been known about the effects of a combined approach, where the early angiography and percutaneous coronary intervention is added during hospitalization, if necessary. OBJECTIVE The aim of the paper is to compare the effects of streptokinase and alteplase, together with the standard modern adjuvant antiplatelets and anticoagulation therapy (aspirin, clopidogrel, enoxaparin) in patients with ST segment elevation acute myocardial infarction, on electrocardiographic and angiographic signs of the achieved myocardial reperfusion. METHOD The prospective study included 127 patients with the first ST segment elevation acute myocardial infarction who were treated with a fibrinolytic agent in the first 6 hours from the chest pain onset. The examined group included 40 patients on the alteplase reperfusion therapy, while the control 87 patients were on the streptokinase therapy. All the patients received the same adjuvant therapy and all were examined by coronary angiography on the 3rd to 10th day of hospitalization. Reperfusion effects were estimated on the basis of the following: ST segment resolution at 60, 90 and 120 minutes, the appearance of reperfusion arrhythmias at the electrocardiogram, percentage of residual stenosis at the 'culprit' artery, TIMI coronary flow at the 'culprit' artery and the appearance of new major adverse coronary events in the 6-month-follow-up period. RESULTS By analysing the resolution of the sum of ST segment elevation in infarction leading 60 minutes after the beginning of the medication application, we received a statistically significantly higher resolution of ST segment in the group of patients who received alteplase (p<0.05). 60 minutes after the application of thrombolytics, 64% of patients at streptokinase showed the absence of ST segment resolution (<30%), and 32% of patients at alteplase (p<0.0001). Reperfusion arrhythmias as the sign of successful myocardial reperfusion were present in 62.5% of patients at alteplase and in 57.4% of patients at streptokinase, but the difference is not statistically significant. There was no statistically significant difference in the degree of residual stenosis at the 'culprit' artery in the compared groups of p
An alternative approach for endocardial pacemaker lead implantation in patient with persistent left superior vena cava
Mitov Vladimir,Peri?i? Zoran,KostiTomislav,Stojkovi? Aleksandar
Srpski Arhiv za Celokupno Lekarstvo , 2010, DOI: 10.2298/sarh1002085m
Abstract: Introduction. Persistent left superior vena cava represents a congenital vascular defect of the venous system, which often makes standard 58 cm endocardial lead placement impossible. Case Outline. A right chamber approach by the left cephalic vein was tried. This was impossible because standard endocardial lead (SJM Isoflex S 1646T, bipolar lead, 58 cm in length, body diameter 7 French) was too short for this patient. A unipolar lead for coronary sinus (Medtronic ATTEIN 4193-88), 88 cm in length, body diameter 4 French, was placed in the posterior branch of the coronary sinus. With such positioning of the lead, a VVI pacemaker pacing was enabled. The operation lasted for 48 minutes, and the time of total X-ray exposure was 9.6 minutes. The values that were achieved were: threshold 0.3 V, pulse width 0.37 ms, maximum R 22.55 mV. Ten months after the implantation, the values were: thresh- old 0.3 V, maximum R 28.8 mV. Conclusion. Persistent left superior vena cava in some cases makes standard 58 cm endocardial lead placement impossible due to its joining to the right atrium over the dilated coronary sinus. Coronary sinus lead placement in the posterior or lateral coronary sinus branch represents an acceptable alternative approach for pacemaker lead placement in these patients.
Nela ?ivkovi?,Aleksandra Stankovi?,Ivana Krsti?,Tomislav Kosti
Acta Medica Medianae , 2009,
Abstract: Evaluating functional status in the patients with rheumatoid arthritis defines the presence of functional limitations and incapacitation. Patients’ ability to perform daily activities is reduced during the disease, and parameters influencing its reduction are numerous. The aim of this research was to examine the relation between joint damage and functional capacities of patients suffering from rheumatoid arthritis.The analysis included 98 patients with rheumatoid arthritis treated at the Institute Niska Banja . The examinees’ HAQ score was determined, after which they were separated into three functional groups, while standard hands and feet radiography determined the level of radiological damage (Larsen score). The majority of patients (41,8%) were characterized by functional disability (HAQ>2,01). The difference in values of Larsen score between the HAQ groups was statistically significant (p<0.001). There was no statistically significant association between the HAQ score and length of disease (p>0.05). The investigation showed that the increase of joint destruction reduces functional ability of patients with rheumatoid arthritis.
Tomislav Kosti,Zoran Peri?i?,Dragan Mili?,Svetlana Apostolovi?
Acta Medica Medianae , 2010,
Abstract: Ventricular perforation is a rare complication of permanent pacemaker implantation. We report a case of 61-year-old woman with sick sinus syndrome who had the dual chamber pacemaker implanted. Five days after the implantation, the perforation of right ventricle by active ventricular fixation lead was detected. 12-lead surface electrocardiography and multislice chest scan are necessary for detection of rare complications after the pacemaker implantation.
Tomislav Kosti,Zoran Peri?i?,Sonja ?alinger Martinovi?,Svetlana Apostolovi?
Acta Medica Medianae , 2009,
Abstract: Sudden cardiac death poses an immense problem in the middle and highly developed countries because its first expression is at the same time the last one. Ventricle tachycardia, the monomorphous and the polymorphous ones, and ventricular fibrillation are rhythm disorders that are most frequently associated with the phenomenon of sudden cardiac death. Ventricular fibrillation is the most common cause of sudden cardiac death within the first hours of the acute myocardial infarction. A 60-year-old man was admitted to our Clinic from a local hospital due to acute onset of chest pain and ECG signs of anterior ST segment elevation myocardial infarction. He had severe rhythm disturbances, about 70 epizodes of ventricular fibrilation (VF). Due to rhytmical instability of the patient, we decided that along with PCI it was necessary to implant ICD twenty-two days after the first acute coronary event.The ICD implantation ensures the best prevention against sudden cardiac death (secondary and primary) in selected high-risk patients and has no alternative for any medicine known so far. It is significant that, lately, the field of application has extended to indication areas of primary prevention of sudden cardiac death, and especially to development of resynchronization implantable cardioverter defibrillator in the heart failure therapy.
Vladimir Mitov,Zoran Peri?i?,Aleksandar Joli?,Tomislav Kosti
Acta Medica Medianae , 2011,
Abstract: Persistent left superior vena cava represents a congenital vascular defect of the venous system, and is usually discovered accidentally. Temporary pacemaker lead placement should be performed under the fluoroscopy control, but also by using the ECG QRS morphology. Echocardiography also represents a reliable noninvasive diagnostic tool for the assessment of temporary pacemaker lead position.
Coronary flow and hemorrhagic complications after alteplase and streptokinase administration in patients with acute myocardial infarction
KostiTomislav,Peri?i? Zoran,Mili? Dragan,Apostolovi? Svetlana
Vojnosanitetski Pregled , 2009, DOI: 10.2298/vsp0903218k
Abstract: Background/Aim. Up-to-date treatment of acute myocardial infarction (AIM) has been based on as early as possible establishment of circulation in ischemic myocardium whether by the use of fibrinolythic therapy and/or urgent coronary intervention which significantly changes the destiny of patients with AMI, but also increases the risk of bleeding. The aim of this study was to compare coronary flow and bleeding complications in patients with acute myocardial infarction with ST-elevation (STEMI) after administration of alteplase or streptokinase. Methods. The study included 254 patients with STEMI. The group I (n = 174) received streptokinase, and the group II (n = 80) received alteplase. We followed frequency of complications such as bleeding and hypotension in the investigated groups of patients, based on the TIMI classification of bleeding, as well as the transience of infarction artery in accordance with TIMI flow. Results. The patients with myocardial infarction after administration of alteplase had statistically significantly higher coronary flow (TIMI- 3), 72.5% as compared to the patients who received streptokinase, 39.2%. Hypotension as complication of fibrynolythic therapy administration occurred in a significantly higher percentage in the group of patients who received streptokinase. There was no statistically significant difference in the appearance of major bleeding in the groups of patients who received streptokinasis and alteplase (6.9% and 7.5%, respectively). Also, there was no difference in the appearance of minor and minimal bleeding among the investigated groups of patients. Conclusion. It was shown that alteplase in a higher number of patients provided TIMI-3 coronary flow as compared to streptokinese. In comparison with streptokinase, a combination of alteplase, enoxaparin and double antiplatelet therapy enabled earlier achievement of coronary flow through previously blocked coronary artery that was more complete (higher frequency of TIMI-3 flow). There were no statistically significant difference in frequency of bleeding, first of all major bleeding, between the groups treated by alteplase and streptokinase.
Transitional justice and reconciliation in Bosnia-Herzegovina: Whose memories, whose justice?
Kosti? Roland
Sociologija , 2012, DOI: 10.2298/soc1204649k
Abstract: This paper shows that transitional justice initiatives such as the trials at the International Criminal Tribunal for the Former Yugoslavia and the State Court of Bosnia and Herzegovina, the Commission for Srebrenica and the establishment of accurate statistics on deaths during the conflict have had only a limited impact on inter-group reconciliation in Bosnia and Herzegovina. Popular attitudes towards these initiatives are captured in surveys conducted in 2005 and 2010. The results are not surprising given that the absence, due to the level of external regulation and control, of a politics of post-Dayton state-building means that domestic politics takes place in an arena of dealing with the past. The international community legitimised the three prevalent conflict narratives as a way of achieving a peace settlement in Dayton. These communal narratives were used in the peace-building phase by the local elites to defend concessions gained during negotiations and to oppose changes imposed by external supervisors of the Dayton Peace Accords. This has transformed the debate over the recent conflict from a transitional process of coming to terms with the past to a permanent state of affairs. This process precludes reconciliation in terms of mutual acknowledgment of suffering and a nuanced understanding of the causes and dynamics of the violent conflict.
Perturbation Theory for Abstract Volterra Equations
Marko Kosti
Abstract and Applied Analysis , 2013, DOI: 10.1155/2013/307684
Some practical issues in the computational design of airfoils for the helicopter main rotor blades
Kosti? Ivan
Theoretical and Applied Mechanics , 2004, DOI: 10.2298/tam0404281k
Abstract: Very important requirement for the helicopter rotor airfoils is zero, or nearly zero moment coefficient about the aerodynamic center. Unlike the old technologies used for metal blades, modern production involving application of plastic composites has imposed the necessity of adding a flat tab extension to the blade trailing edge, thus changing the original airfoil shape. Using computer program TRANPRO, the author has developed and verified an algorithm for numerical analysis in this design stage, applied it on asymmetrical reflex camber airfoils, determined the influence of angular tab positioning on the moment coefficient value and redesigned some existing airfoils to include properly positioned tabs that satisfy very low moment coefficient requirement. .
Page 1 /719
Display every page Item

Copyright © 2008-2017 Open Access Library. All rights reserved.