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Search Results: 1 - 10 of 14072 matches for " Ting-Jung Kuo "
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Yau's Gradient Estimate and Liouville Theorem for Positive Pseudo-Harmonic functions in aComplete Pseudo-Hermitian Manforld
Shu-Cheng Chang,Ting-Jung Kuo,Jingzhi Tie
Mathematics , 2015,
Abstract: In this paper, we first derive the sub-gradient estimate for positive pseudoharmonic functions in a complete pseudohermitian $(2n+1)$-manifold $% (M,J,\theta )\ $which satisfies the CR sub-Laplacian comparison property. It is served as the CR analogue of Yau's gradient estimate. Secondly, we obtain the Bishop-type sub-Laplacian comparison theorem in a class of complete noncompact pseudohermitian manifolds. Finally we have shown the natural analogue of Liouville-type theorems for the sub-Laplacian in a complete pseudohermitian manifold of vanishing pseudohermitian torsion tensors and nonnegative pseudohermitian Ricci curvature tensors.
Hamiltonian system for the elliptic form of Painlevé VI equation
Zhijie Chen,Ting-Jung Kuo,Chang-Shou Lin
Mathematics , 2015,
Abstract: In literature, it is known that any solution of Painlev\'{e} VI equation governs the isomonodromic deformation of a second order linear Fuchsian ODE on $\mathbb{CP}^{1}$. In this paper, we extend this isomonodromy theory on $\mathbb{CP}^{1}$ to the moduli space of elliptic curves by studying the isomonodromic deformation of the generalized Lam\'{e} equation. Among other things, we prove that the isomonodromic equation is a new Hamiltonian system, which is equivalent to the elliptic form of Painlev\'{e} VI equation for generic parameters. For Painlev\'{e} VI equation with some special parameters, the isomonodromy theory of the generalized Lam\'{e} equation greatly simplifies the computation of the monodromy group in $\mathbb{CP}^{1}$. This is one of the advantages of the elliptic form.
Fuzzy Constraint-Based Agent Negotiation
Menq-Wen Lin,K Robert Lai,Ting-Jung Yu,
Menq-Wen Lin
,K. Robert Lai,and Ting-Jung Yu

计算机科学技术学报 , 2005,
Abstract: Conflicts between two or more parties arise for various reasons and perspectives. Thus, resolution of conflicts frequently relies on some form of negotiation. This paper presents a general problem-solving framework for modeling multi-issue multilateral negotiation using fuzzy constraints. Agent negotiation is formulated as a distributed fuzzy constraint satisfaction problem (DPCSP). Fuzzy constrains are thus used to naturally represent each agent's desires involving imprecision and human conceptualization, particularly when lexical imprecision and subjective matters are concerned. On the other hand, based on fuzzy constraint-based problem-solving, our approach enables an agent not only to systematically relax fuzzy constraints to generate a proposal, but also to employ fuzzy similarity to select the alternative that is subject to its acceptability by the opponents. This task of problem-solving is to reach an agreement that benefits all agents with a high satisfaction degree of fuzzy constraints, and move towards the deal more quickly since their search focuses only on the feasible solution space. An application to multilateral negotiation of a travel planning is provided to demonstrate the usefulness and effectiveness of our framework.
Clinical Analysis and Strategy for Liver Transplantation in Patients with Pre-existing Portal Vein Thrombosis
Tsung-Han Wu,Yann-Sheng Lin,Chen-Fang Lee,Ting-Jung Wu
Chang Gung Medical Journal , 2011,
Abstract: Background: Liver transplantation (LT) in patients with portal vein thrombosis (PVT)remains a challenge for transplant surgeons. In this study, we included agroup of patients with PVT who underwent LT, and analyzed patient outcomes.Methods: A total of 356 patients who underwent LT consisting of 167 cases ofdeceased donor LT and 189 cases of live donor LT at Chang Gung MemorialHospital Linkou Medical Center between September 1996 and June 2009were retrospectively reviewed; 24 (6.7%) of these patients had PVT at transplantation. Their clinical features, surgical management, and outcomes wereanalyzed.Results: Surgical management of patients with PVT included a thrombectomy followed by direct anastomosis between the recipient’s and the liver graft portalvein (PV) (n = 13), interposition vein graft between the recipient’s coronaryvein (CV) and the liver graft PV (n = 3), direct anastomosis of the recipient’sCV and the liver graft PV (n = 1), interposition jump graft from the recipient’s superior mesenteric vein to the liver graft PV (n = 4), and transection ofthe thrombotic PV followed by interposition of a venous graft between therecipient’s PV and the liver graft PV (n = 3). There were 7 hospital mortalities. The mean follow-up for the 17 surviving patients was 36.3 months(range, 3.4–105.1 months), and 14 patients were still alive at the end of thestudy. Four patients (16.7%) had rethrombosis of portal inflow after LT.Patients with PVT undergoing LT had a significantly higher mortality rate (p= 0.033) than patients without PVT undergoing LT. However, there was nosignificant difference in the cumulative survival rates (p = 0.0696). Furtheranalysis of patient survival according to PVT grade, venous graft application,and reconstructed portal flow routes also exhibited no significant differences.Conclusions: LT for patients with PVT is clinically feasible and should not be considered acontraindication. However, a favorable outcome is achievable only with idealsurgical management to overcome PVT during LT.
Complexity of the Tensegrity Structure for Dynamic Energy and Force Distribution of Cytoskeleton during Cell Spreading
Ting-Jung Chen,Chia-Ching Wu,Ming-Jer Tang,Jong-Shin Huang,Fong-Chin Su
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0014392
Abstract: Cytoskeleton plays important roles in intracellular force equilibrium and extracellular force transmission from/to attaching substrate through focal adhesions (FAs). Numerical simulations of intracellular force distribution to describe dynamic cell behaviors are still limited. The tensegrity structure comprises tension-supporting cables and compression-supporting struts that represent the actin filament and microtubule respectively, and has many features consistent with living cells. To simulate the dynamics of intracellular force distribution and total stored energy during cell spreading, the present study employed different complexities of the tensegrity structures by using octahedron tensegrity (OT) and cuboctahedron tensegrity (COT). The spreading was simulated by assigning specific connection nodes for radial displacement and attachment to substrate to form FAs. The traction force on each FA was estimated by summarizing the force carried in sounding cytoskeletal elements. The OT structure consisted of 24 cables and 6 struts and had limitations soon after the beginning of spreading by declining energy stored in struts indicating the abolishment of compression in microtubules. The COT structure, double the amount of cables and struts than the OT structure, provided sufficient spreading area and expressed similar features with documented cell behaviors. The traction force pointed inward on peripheral FAs in the spread out COT structure. The complex structure in COT provided further investigation of various FA number during different spreading stages. Before the middle phase of spreading (half of maximum spreading area), cell attachment with 8 FAs obtained minimized cytoskeletal energy. The maximum number of 12 FAs in the COT structure was required to achieve further spreading. The stored energy in actin filaments increased as cells spread out, while the energy stored in microtubules increased at initial spreading, peaked in middle phase, and then declined as cells reached maximum spreading. The dynamic flows of energy in struts imply that microtubules contribute to structure stabilization.
Efficacy of surgical resection in management of isolated extrahepatic metastases of hepatocellular carcinoma
Kun-Ming Chan, Ming-Chin Yu, Ting-Jung Wu, Chen-Fang Lee, Tse-Ching Chen, Wei-Chen Lee, Miin-Fu Chen
World Journal of Gastroenterology , 2009,
Abstract: AIM: To clarify the benefit of surgical excision for patients with extrahepatic metastases of hepatocellular carcinoma (HCC).METHODS: We retrospectively reviewed the medical records of 140 patients with pathologically proven extrahepatic metastases of HCC and evaluated the outcomes of those who had undergone surgical resection (SR) for extrahepatic metastatic lesions. Prognoses made on the basis of extrahepatic metastatic sites were also examined.RESULTS: The survival rates of patients who underwent SR of extrahepatic metastases were significantly better than those of patients who did not receive SR. For the SR group, 1- and 3-year survival rates were 24% and 7%, respectively, while for the non-resection group, the survival rates were 8% and 0%, respectively (P < 0.0001). Survival rates related to metastatic sites were also significantly superior after SR of extrahepatic metastases: median survivals were 32 mo with lung metastasis, 10 mo with bone metastasis, 6.1 mo with brain metastasis.CONCLUSION: SR can provide survival benefits for patients with 1 or 2 isolated extrahepatic metastases and who concurrently exhibit good hepatic functional reserve and general performance status as well as successful treatment of intrahepatic HCC.
Large Fragment Pre-S Deletion and High Viral Load Independently Predict Hepatitis B Relapse after Liver Transplantation
Ting-Jung Wu, Tse-Ching Chen, Frank Wang, Kun-Ming Chan, Ruey-Shyang Soong, Hong-Shiue Chou, Wei-Chen Lee, Chau-Ting Yeh
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0032189
Abstract: Hepatitis B virus (HBV) associated end-stage liver diseases are the leading causes of liver transplantation (LT) in Taiwan. Relapse of hepatitis B occurs after LT, raising the risk of graft failure and reducing patient survival. Although several oral antiviral agents have been approved for anti-HBV treatment, lamivudine (LAM) remained to be the most widely used preventive regimen in Taiwan. While several clinical predictors have been identified for hepatitis B relapse, the predictive roles of the histopathological characteristics in liver explants as well as the genotypic features of the viruses in pre-LT serum samples have not been assessed. Between September 2002 and August 2009, 150 consecutive hepatitis B surface antigen (HBsAg) positive patients undergoing LT were included for outcome analysis following assessment of the clinicopathological and virological factors prior to LT. Kaplan-Meier analyses discovered that pre-operative LAM treatment ≤3 months; membranous distribution and higher expression of tissue HBsAg in liver explants; preoperative viral load ≧106 copies/ml; and presence of large fragment (>100 base pairs) pre-S deletion (LFpreSDel) correlated significantly with hepatitis B relapse. Multivariate Cox regression analysis showed that the presence of LFpreSDel (P = 0.001) and viral load ≧106 copies/mL (P = 0.023) were independent predictors for hepatitis B relapse. In conclusion, besides high viral load, LFpreSDel mutation is an important independent predictor for hepatitis B relapse after LT. More aggressive preventive strategies should be applied for patients carrying these risk factors.
Surgical treatment and prognostic analysis for gastrointestinal stromal tumors (GISTs) of the small intestine: before the era of imatinib mesylate
Ting-Jung Wu, Li-Yu Lee, Chun-Nan Yeh, Pei-Yu Wu, Tzu-Chieh Chao, Tsann-Long Hwang, Yi-Yin Jan, Miin-Fu Chen
BMC Gastroenterology , 2006, DOI: 10.1186/1471-230x-6-29
Abstract: The clinicopathologic and follow-up records of 100 small intestine GIST patients who were treated at Chung Gung Memorial Hospital between 1983 and 2002 were retrospectively reviewed. Clinical and pathological factors were assessed for long-term DFS and OS by using a univariate log-rank test and a multivariate Cox proportional hazard model.The patients included 52 men and 48 women. Their ages ranged from 27 to 82 years. Among the 85 patients who underwent curative resection, 44 (51.8%) developed disease recurrence (liver metastasis was the most common form of recurrence). The follow-up period ranged from 5 to 202 months (median: 33.2 months). The 1-, 3-, and 5-year DFS and OS rates were 85.2%, 53.8%, and 43.7%, and 91.5%, 66.6%, and 50.5%, respectively. Using multivariate analysis, it was found that high tumor cellularity, mitotic count >5/50 high-power field, and a Ki-67 index ≧10% were three independent factors that were inversely associated with DFS. However, absence of tumor perforation, mitotic count < 5/50 high power field, and tumor with low cellularity were predictors of long-term favorable OS.Tumors with low cellularity, low mitotic count, and low Ki-67 index, which indicate low risk, predict a more favorable DFS for small intestine GIST patients undergoing curative resection. Absence of tumor perforation with low mitotic count and low cellularity, which indicates low risk, can predict long-term OS for small intestine GIST patients who have undergone curative resection.Mesenchymal tumors of the gastrointestinal (GI) tract are rare, comprising only 0.1% to 3% of all GI neoplasms [1]. Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the GI tract. These tumors are composed of tumor cells from the interstitial cells of Cajal [2,3], which are considered to be GI pacemaker cells.Gain-of-function mutations in the c-kit proto-oncogene and overexpression of the kit protein can occur [4,5], and result in a constitutive stimulus to tumo
Analysis of the recurrence risk factors for the patients with hepatocellular carcinoma meeting University of California San Francisco criteria after curative hepatectomy
Ruey-Shyang Soong, Ming-Chin Yu, Kun-Ming Chan, Hong-Shiue Chou, Ting-Jung Wu, Chen-Fang Lee, Tsung-Han Wu, Wei-Chen Lee
World Journal of Surgical Oncology , 2011, DOI: 10.1186/1477-7819-9-9
Abstract: Nevertheless, there is no doubt that for HCC, liver transplantation is a superior treatment option to liver resection, where long-term tumor-free survival is concerned. Adult-to-adult living donor liver transplantation is a well-established technique now. Liver transplantation for patients with HCC becomes feasible if a living donor wishes to donate part of the liver to save a member of the family. To optimize the benefit of living donor liver transplantation for HCC patients, the question of how to select the right patients to have liver transplantation is very important.This study aims to identify the patients who accepted hepatectomy for a tumor/tumors and were within University of California San Francisco (UCSF) criteria[4], but had a poor 5-year disease-free survival rate (DFS). We analyze the pre-operative data of the patients and attempt to find the pre-operative risk factors of HCC recurrence. These risk factors could be indicators for clinical doctors to define and identify the patients with a high risk of tumor recurrence and to arrange liver transplantation rather than hepatectomy as the first treatment option.A total of 1595 patients underwent hepatectomy for HCC from 1983 to 2005 in Chang Gung Medical hospital, Taipei, for whom data were collected. The patient selection criteria in this study were (1) tumor number and size within UCSF criteria, (2) no major vessel invasion, (3) no distal metastasis, and (4) age < 70 years old (based on the upper limited age of liver transplantation in HCC in this institute). Totally, 840 cases matching the criteria were the object of this study. Hospital mortality cases (expired in post-operative 30 days) were excluded from this study. Patients were further divided into two groups: group A (n = 583 (69.4%)), having tumor recurrence within 5 years after hepatectomy, and group B (n = 257 (30.6%)), showing no tumor recurrence within 5 years (Figure 1). Patient clinical data included gender, diabetes, end-stage renal diseas
Social Security, Retirement and Economic Growth  [PDF]
Kuo-Ting Hua
Theoretical Economics Letters (TEL) , 2018, DOI: 10.4236/tel.2018.815214
Abstract:

Population aging alters decisions of retirement and intergenerational transfers simultaneously. With the consideration of both decisions, this paper investigates the economic impacts of population aging in an Overlapping-Generation (OLG) model under social security coverage. Results show that the economy grows slower with voluntarily increased elderly labor supply than otherwise. Ignoring the interactions between these decisions may lead to a serious mis-estimation. Results also show that mandatory postponing retirement creates disincentive to saving and hinders the economy. To prevent the economy from slowing down and fertility from falling, mandatory postponing retirement must be accompanied by a lower replacement ratio.

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