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Search Results: 1 - 10 of 12494 matches for " Tian Dequan "
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SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity
Carrasquillo Robert,Tian Dequan,Krishna Sneha,Pollak Martin R
BMC Cell Biology , 2012, DOI: 10.1186/1471-2121-13-33
Abstract: Background Transient receptor potential canonical (TRPC) channels are non-selective cation channels involved in receptor-mediated calcium signaling in diverse cells and tissues. The canonical transient receptor potential 6 (TRPC6) has been implicated in several pathological processes, including focal segmental glomerulosclerosis (FSGS), cardiac hypertrophy, and pulmonary hypertension. The two large cytoplasmic segments of the cation channel play a critical role in the proper regulation of channel activity, and are involved in several protein-protein interactions. Results Here we report that SNF8, a component of the endosomal sorting complex for transport-II (ESCRT-II) complex, interacts with TRPC6. The interaction was initially observed in a yeast two-hybrid screen using the amino-terminal cytoplasmic domain of TRPC6 as bait, and confirmed by co-immunoprecipitation from eukaryotic cell extracts. The amino-terminal 107 amino acids are necessary and sufficient for the interaction. Overexpression of SNF8 enhances both wild-type and gain-of-function mutant TRPC6-mediated whole-cell currents in HEK293T cells. Furthermore, activation of NFAT-mediated transcription by gain-of-function mutants is enhanced by overexpression of SNF8, and partially inhibited by RNAi mediated knockdown of SNF8. Although the ESCRT-II complex functions in the endocytosis and lysosomal degradation of transmembrane proteins, SNF8 overexpression does not alter the amount of TRPC6 present on the cell surface. Conclusion SNF8 is novel binding partner of TRPC6, binding to the amino-terminal cytoplasmic domain of the channel. Modulating SNF8 expression levels alters the TRPC6 channel current and can modulate activation of NFAT-mediated transcription downstream of gain-of-function mutant TRPC6. Taken together, these results identify SNF8 as a novel regulator of TRPC6.
Approximate Solution of Fuzzy Matrix Equations with LR Fuzzy Numbers  [PDF]
Xiaobin Guo, Dequan Shang
Advances in Pure Mathematics (APM) , 2012, DOI: 10.4236/apm.2012.26056
Abstract: In the paper, a class of fuzzy matrix equations AX=B where A is an m × n crisp matrix and is an m × p arbitrary LR fuzzy numbers matrix, is investigated. We convert the fuzzy matrix equation into two crisp matrix equations. Then the fuzzy approximate solution of the fuzzy matrix equation is obtained by solving two crisp matrix equations. The existence condition of the strong LR fuzzy solution to the fuzzy matrix equation is also discussed. Some examples are given to illustrate the proposed method. Our results enrich the fuzzy linear systems theory.
Fuzzy Symmetric Solutions of Fuzzy Matrix Equations
Xiaobin Guo,Dequan Shang
Advances in Fuzzy Systems , 2012, DOI: 10.1155/2012/318069
Abstract: The fuzzy symmetric solution of fuzzy matrix equation , in which is a crisp nonsingular matrix and is an fuzzy numbers matrix with nonzero spreads, is investigated. The fuzzy matrix equation is converted to a fuzzy system of linear equations according to the Kronecker product of matrices. From solving the fuzzy linear system, three types of fuzzy symmetric solutions of the fuzzy matrix equation are derived. Finally, two examples are given to illustrate the proposed method. 1. Introduction Linear systems always have important applications in many branches of science and engineering. In many applications, at least some of the parameters of the system are represented by fuzzy rather than crisp numbers. So, it is immensely important to develop a numerical procedure that would appropriately treat general fuzzy linear systems and solve them. The concept of fuzzy numbers and arithmetic operations with these numbers was first introduced and investigated by Zadeh [1], Dubois et al. [2], and Nahmias [3]. A different approach to fuzzy numbers and the structure of fuzzy number spaces was given by Puri and Ralescu [4], Goetschell et al. [5], and Wu and Ming [6, 7]. Since Friedman et al. [8, 9] proposed a general model for solving an fuzzy linear systems whose coefficients matrix is crisp and the right-hand side is an arbitrary fuzzy numbers vector by an embedding approach in 1998, many works have been done about how to deal with some fuzzy linear systems with more advanced forms such as dual fuzzy linear systems (DFLSs), general fuzzy linear systems (GFLSs), fully fuzzy linear systems (FFLSs), dual full fuzzy linear systems (DFFLSs), and general dual fuzzy linear systems (GDFLSs). These works were performed mainly by Allahviranloo et al. [10–13], Abbasbandy et al. [14–17], Wang et al. [18, 19] and Dehghan et al. [20, 21], among others. However, for a fuzzy matrix equation which always has a wide use in control theory and control engineering, few works have been done in the past decades. In 2010, Guo et al. [22–24] investigated a class of fuzzy matrix equations in which is an crisp matrix and the right-hand side matrix is an fuzzy numbers matrix by means of the block Gaussian elimination method and the undetermined coefficients method, and they studied least squares solutions of the inconsistent fuzzy matrix equation by using the generalized inverses. In 2011, Allahviranloo and Salahshour [25] obtained fuzzy symmetric approximate solutions of fuzzy linear systems by solving a crisp system of linear equations and a fuzzified interval system of linear equations.
DACH: An Efficient and Reliable Way to Integrate WSN with IPv6
Dequan Yang,Qiao Guo
International Journal of Distributed Sensor Networks , 2012, DOI: 10.1155/2012/714786
Fuzzy Approximate Solution of Positive Fully Fuzzy Linear Matrix Equations
Xiaobin Guo,Dequan Shang
Journal of Applied Mathematics , 2013, DOI: 10.1155/2013/178209
Approximate Solution of LR Fuzzy Sylvester Matrix Equations
Xiaobin Guo,Dequan Shang
Journal of Applied Mathematics , 2013, DOI: 10.1155/2013/752760
DACH: An Efficient and Reliable Way to Integrate WSN with IPv6
Dequan Yang,Qiao Guo
International Journal of Distributed Sensor Networks , 2012, DOI: 10.1155/2012/714786
Abstract: IPv6 has many advantages such as the massive amount of addresses, high security, and high robustness, which are beneficial for wireless sensor networks (WSNs). However, it is almost impossible to use IPv6 directly in WSN due to its huge energy consumption. This paper proposes a double adaptively clustering hierarchy (DACH) algorithm which enables using IPv6 in WSN in an efficient and reliable way. Firstly, we present a clustering method to adaptively divide the whole sensor network into clusters according to its energy consumption in the last round. Then we propose an adaptive cluster head selection algorithm which employs a strategy to choose the most suitable cluster heads; meantime, this selection algorithm is integrated into DACH. Finally, the complete framework is built between headers and their slave nodes based on IEEE 802.15.4, and IPv6 is used to connect the headers and the base stations. Experimental and simulation results demonstrate that the DACH algorithm has lower time and energy consumption. Moreover, it is more reliable and applicable than many other IP-based WSN algorithms. 1. Introduction One of the most important techniques of this decade is wireless sensor networks (WSNs). In the last twenty years, interpersonal communication has become very popular with the booming internet technology. Similarly, with the development of??WSNs [1], the same phenomenon will occur, and people will benefit a lot from this new information exchange technology. When WSN is as widely used as the internet, people can turn on their air conditioners at home when they are still on their way; the information of snow depth of every valley of Alps can be measured and collected by sensors and sent to people for making decisions about holiday skiing; any equipment of a city can send an alarm to the fire station automatically when the temperature is beyond the normal range, and so forth. Without access to the internet, WSN is just a usual local network with its limited power. However, when IPv6 joins, WSN becomes magic and powerful, for IPv6 has a lot of advantages, such as massive addresses, high security, and good QoS service [2]. Since TCP/IP is limited with factors like too much energy cost and low battery frequent data transmission at the sensor nodes, IPv6-based WSN is more favorite for the researchers. However, for WSN, header overhead problem in IPv6 is more serious than that in IPv4. Usually, the monitoring signal, control signal, and measured data of a sensor is no more than 10 bytes [3]. If IPv6 is introduced directly, the header overhead will consume more
Communication Networking Schemes for Wide Area Electric Vehicle Energy Service Network  [PDF]
Dequan Gao, Jinping Cao, Yiying Zhang, Xiuli Wang
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.54B268

Electric vehicles (EVs) are an emerging type of mobile intelligent power consumption devices in Smart Grid as new green transport tools. In order to provide a powerful automation and intelligence support for wide area electric vehicles energy service network, we analyze the network infrastructure and communications demands of various terminals, devices and monitoring systems distributed in wide area electric vehicle energy service network. According to interactive user services scenarios and energy operations intelligent monitoring, we propose multimode communication integration architecture for wide area electric vehicle energy service network by means of the fusion of the Internet of Things (IoT) technology. Then, we design different networking schemes in access networks and backbone transmission networks meeting multi-scene and multi-operation interaction requirements. The networking schemes will provide efficient technical support to implement intelligent, cross-regional, interactive energy services for electric vehicle users.

Availability Equivalence Analysis of a Repairable Series-Parallel System
Linmin Hu,Dequan Yue,Dongmei Zhao
Mathematical Problems in Engineering , 2012, DOI: 10.1155/2012/957537
Abstract: This paper studies the availability equivalence of different designs of a repairable series-parallel system. Under the assumption that the system components have constant failure rates and repair rates, we derive the availability of the original and improved systems according to reduction, increase, hot duplication, warm duplication and cold duplication methods, respectively. The availability equivalence factor is introduced to compare different system designs. Two types of availability equivalence factors of the system are obtained. Numerical examples are provided to interpret how to utilize the obtained results.
Disciplinary Characteristics of Theories as well as Modernization and Digitalization of Traditional Chinese Medicine

Ren Dequan,

世界科学技术-中医药现代化 , 2002,
Abstract: The scientific contents and disciplinary characteristics of traditional Chinese medicine have determined that traditional Chinese medical science is such a discipline of life sciences that both traditional Chinese medical science and Western medical science can be complements to each other, and therefore the former should continue developing independently. As for the modernization of the traditional theories of traditional Chinese medicine, its key is to present the expression of such theories by means of digitalization and thus establish their digitalized system. The digitalization of the four methods of diagnosis of traditional Chinese medicine as well as the research and development of the supplementary instruments related to the four methods of diagnosis are all keys to the modernization of traditional Chinese medical science, traditional Chinese medicine, the hospitals of traditional Chinese medicine and the curative effects of traditional Chinese medicines.
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