oalib

OALib Journal期刊

ISSN: 2333-9721

费用:99美元

投稿

时间不限

2017 ( 44 )

2016 ( 85 )

2015 ( 2183 )

2014 ( 2799 )

自定义范围…

匹配条件: “Thomas Sick NIELSEN” ,找到相关结果约32876条。
列表显示的所有文章,均可免费获取
第1页/共32876条
每页显示
Brugerunders gelser med GPS, Eksempler fra parkunders gelser i Aalborg
Thomas Sick Nielsen,Henrik Harder,Peter Bro,Anders Kvist Simonsen
Geoforum Perspektiv , 2008,
Abstract:
Land Use Scenarios for Greater Copenhagen: Modelling the Impact of the Fingerplan
Christian FERTNER,Gertrud J?RGENSEN,Thomas Sick NIELSEN
Journal of Settlements and Spatial Planning , 2012,
Abstract: Urban planning and development in Denmark can be characterised by a relatively strong planning framework. Land use scenarios based on empirically derived dynamics of urban growth are practically never applied. However, modelling approaches do offer a methodology to explore the pressures in an urban region, as well as an approach to understand urban development patterns outside the ‘spatial masterplan’. In this context we will present the results of a modelling exercise addressing future land use change in the metropolitan area of Copenhagen, Denmark, and the impact of the current regional planning framework, the “Fingerplan 2007”. We test three policy scenarios and analyse different effects on urban growth by using the Metronamica model from the Dutch-based Research Institute for Knowledge Systems (RIKS). We analyse the possibilities to elaborate a practical and useful outcome within a relatively short period of time. The set-up and the results were discussed with a few experts from the Danish Ministry of the Environment and its value as discussion input recognized. The approach offers a lot of possibilities to discuss urban growth and spatial planning policies, even in a country with a strong planning framework as in Denmark.
SNPFile – A software library and file format for large scale association mapping and population genetics studies
Jesper Nielsen, Thomas Mailund
BMC Bioinformatics , 2008, DOI: 10.1186/1471-2105-9-526
Abstract: We describe a new binary file format for SNP data, together with a software library for file manipulation. The file format stores genotype data together with any kind of additional data, using a flexible serialisation mechanism. The format is designed to be IO efficient for the access patterns of most multi-locus analysis methods.The new file format has been very useful for our own studies where it has significantly reduced the informatics burden in keeping track of various secondary data, and where the memory and IO efficiency has greatly simplified analysis runs. A main limitation with the file format is that it is only supported by the very limited set of analysis tools developed in our own lab. This is somewhat alleviated by a scripting interfaces that makes it easy to write converters to and from the format.High-throughput genotyping technology has enabled cost effective typing of thousands of individuals in hundred of thousands of markers for use in genome wide studies [1], in particular genome disease association studies [2-7].There are currently no standard file format for storing such genotype data, and most major analysis tools define their own textual input and output formats. Only a few tools supports several input formats, and often several conversion scripts needs to be implemented in a study. These file formats of analysis tools usually only represent a restricted set of the data collected for the study – only the data necessary for the computations provided by the program – so a study either needs a secondary format for storing all data, with converter programs for import/export to analysis tools, or need several files for storing various types of data.While spreadsheets and plain text files were adequate, if not optimal, solutions earlier, the increased data size mandates more efficient solutions. While plain text files formats have the advantage that they are human readable and can be edited in any text editor to correct mistakes, they have two maj
Video Stippling
Thomas Houit,Frank Nielsen
Computer Science , 2010,
Abstract: In this paper, we consider rendering color videos using a non-photo-realistic art form technique commonly called stippling. Stippling is the art of rendering images using point sets, possibly with various attributes like sizes, elementary shapes, and colors. Producing nice stippling is attractive not only for the sake of image depiction but also because it yields a compact vectorial format for storing the semantic information of media. Moreover, stippling is by construction easily tunable to various device resolutions without suffering from bitmap sampling artifacts when resizing. The underlying core technique for stippling images is to compute a centroidal Voronoi tessellation on a well-designed underlying density. This density relates to the image content, and is used to compute a weighted Voronoi diagram. By considering videos as image sequences and initializing properly the stippling of one image by the result of its predecessor, one avoids undesirable point flickering artifacts and can produce stippled videos that nevertheless still exhibit noticeable artifacts. To overcome this, our method improves over the naive scheme by considering dynamic point creation and deletion according to the current scene semantic complexity, and show how to effectively vectorize video while adjusting for both color and contrast characteristics. Furthermore, we explain how to produce high quality stippled ``videos'' (eg., fully dynamic spatio-temporal point sets) for media containing various fading effects, like quick motions of objects or progressive shot changes. We report on practical performances of our implementation, and present several stippled video results rendered on-the-fly using our viewer that allows both spatio-temporal dynamic rescaling (eg., upscale vectorially frame rate).
Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) in Preclinical Studies of Antivascular Treatments
Thomas Nielsen,Thomas Wittenborn,Michael R. Horsman
Pharmaceutics , 2012, DOI: 10.3390/pharmaceutics4040563
Abstract: Antivascular treatments can either be antiangiogenic or targeting established tumour vasculature. These treatments affect the tumour microvasculature and microenvironment but may not change clinical measures like tumour volume and growth. In research on antivascular treatments, information on the tumour vasculature is therefore essential. Preclinical research is often used for optimization of antivascular drugs alone or in combined treatments. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is an in vivo imaging method providing vascular information, which has become an important tool in both preclinical and clinical research. This review discusses common DCE-MRI imaging protocols and analysis methods and provides an overview of preclinical research on antivascular treatments utilizing DCE-MRI.
Elastic Electron Scattering from Light Nuclei
Ingo Sick
Physics , 2002, DOI: 10.1016/S0146-6410(01)00156-9
Abstract: The charge and magnetic form factors of light nuclei, mainly for mass numbers A<=4, provide a sensitive test of our understanding of nuclei. A number of "exact" calculations of the wave functions starting from the nucleon-nucleon interaction are available. The treatment of two-body effects needed in the calculation of the electromagnetic form factors has made significant progress. Many electron scattering experiments have provided an extensive data base from which the various (mainly elastic) form factors can be extracted. This review discusses the data and the determination of the form factors, and compares them to the results of theory.
Zemach moments of 3He and 4He
Ingo Sick
Physics , 2014, DOI: 10.1103/PhysRevC.90.064002
Abstract: We use the world data on elastic electron scattering on 3He and 4He to determine the Zemach moments _(2) and _(2). These quantities are required to interpret the Lamb shift and HFS data of muonic Helium presently being measured at PSI by the CREMA collaboration. The rms-radii are determined as well.
On the rms-radius of the proton
Ingo Sick
Physics , 2003, DOI: 10.1016/j.physletb.2003.09.092
Abstract: We study the world data on elastic electron-proton scattering in order to determine the proton charge rms-radius. After accounting for the Coulomb distortion and using a parameterization that allows to deal properly with the higher moments we find a radius of 0.895+-0.018 fm, which is significantly larger than the radii used in the past.
Form factors and radii of light nuclei
Ingo Sick
Physics , 2015,
Abstract: We discuss the determination of electromagnetic form factors from the {\em world} data on electron-nucleus scattering for nuclei $Z \leq 3$, with particular emphasis on the derivation of the moments required for comparison with measurements from electronic/muonic atoms and isotope shifts.
A Method to Compute Multiplicity Corrected Confidence Intervals for Odds Ratios and Other Relative Effect Estimates
Jimmy Thomas Efird,Susan Searles Nielsen
International Journal of Environmental Research and Public Health , 2008, DOI: 10.3390/ijerph5050394
Abstract: Epidemiological studies commonly test multiple null hypotheses. In some situations it may be appropriate to account for multiplicity using statistical methodology rather than simply interpreting results with greater caution as the number of comparisons increases. Given the one-to-one relationship that exists between confidence intervals and hypothesis tests, we derive a method based upon the Hochberg step-up procedure to obtain multiplicity corrected confidence intervals (CI) for odds ratios (OR) and by analogy for other relative effect estimates. In contrast to previously published methods that explicitly assume knowledge of P values, this method only requires that relative effect estimates and corresponding CI be known for each comparison to obtain multiplicity corrected CI.
第1页/共32876条
每页显示


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.