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Search Results: 1 - 10 of 14154 matches for " The LUNA Collaboration "
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A randomised controlled trial to assess the efficacy of Laparoscopic Uterosacral Nerve Ablation (LUNA) in the treatment of chronic pelvic pain: The trial protocol [ISRCTN41196151]
The LUNA Trial Collaboration
BMC Women's Health , 2003, DOI: 10.1186/1472-6874-3-6
Abstract: The principal objective is to test the hypothesis that in women with chronic pelvic pain in whom diagnostic laparoscopy reveals either no pathology or mild endometriosis (AFS score ≤ 5) LUNA alleviates pain and improves life quality at 12 months. A multi-centre, prospective, randomised-controlled-trial will be carried out with blind assessment of outcomes in eligible consenting patients randomised at diagnostic laparoscopy to LUNA (experimental group) or to no pelvic denervation (control group). Postal questionnaires including visual analogue scale for pain (primary outcome), an index of sexual satisfaction and the EuroQoL 5D-EQ instrument (secondary outcomes) will be administered at 3, 6 and 12 months. The primary assessment of the effectiveness of LUNA will be from comparison of outcomes at the one-year follow-up, although the medium-term and longer-term risks and benefits of LUNA will also be evaluated.The sample size for this trial has been estimated as 420 patients in total using the hypothesis that LUNA will alleviate pain symptoms (i.e. reduce pain scores on a VAS) more than no intervention at one-year following diagnostic laparoscopy and taking into consideration 20% loss to follow-up. The intention to treat analysis to address the principal research questions will be conducted using the one-year follow-up data.Pelvic pain remains the single most common indication for referral to a Gynaecology clinic accounting for 20% of all outpatient appointments [1,2]. Five percent of all new appointments are for chronic pelvic pain[3]. It continues to be one of the most difficult and perplexing problems encountered in Gynaecology. Pelvic pain has a major impact on health-related quality of life, work productivity and health care utilisation. It is also a major cause of workplace absenteeism [4]. An estimated 158 million pounds are spent annually on the management of this condition in the health service [5]. In primary care, the annual prevalence is 38/1000 in women aged
Astrophysical S-factor of 14N(p,g)15O
the LUNA Collaboration,A. Formicola,G. Imbriani,H. Costantini
Physics , 2003,
Abstract: We report on a new measurement of the 14N(p,g)15O capture cross section at E_p = 140 to 400 keV using the 400 kV LUNA accelerator facility. The uncertainties have been reduced with respect to previous measurements and their analysis. We have analyzed the data using the R-matrix method and we find that the ground state transition accounts for about 15 % of the total S-factor. The main contribution to the S-factor is given by the transition to the 6.79 MeV state. We find a total S(0) = 1.7+/-0.2 keV b.
Developing an Advanced Prototype of the Acousto-Optical Radio-Wave Spectrometer for Studying Star Formation in the Milky Way  [PDF]
Alexandre S. Shcherbakov, Abraham Luna
International Journal of Astronomy and Astrophysics (IJAA) , 2014, DOI: 10.4236/ijaa.2014.41012
Abstract:

The designed practically prototype of an advanced acousto-optical radio-wave spectrometer is presented in a view of its application to investigating the Milky Way star formation problems. The potential areas for observations of the cold interstellar medium, wherein such a spectrometer can be exploited successfully at different approximations, are: 1) comparison of the Milky Way case with extragalactic ones at scale of the complete galactic disk; 2) global studies of the Galactic spiral arms; and 3) characterization of specific regions like molecular clouds or star clusters. These aspects allow us to suggest that similar instrument will be really useful. The developed prototype of spectrometer is able to realize multi-channel wideband parallel spectrum analysis of very-high-frequency radio-wave signals with an improved resolution power exceeding 103. It includes the 1D-acousto-optic wide-aperture cell as the input device for real-time scale data processing. Here, the current state of developing this acousto-optical spectrometer in frames of the astrophysical instrumentation is briefly discussed, and the data obtained experimentally with a tellurium dioxide crystalline acousto-optical cell are presented. Then, we describe a new technique for more precise spectrum analysis within an algorithm of the collinear wave heterodyning. It implies a two-stage integrated processing, namely, the wave heterodyning of a signal in an acoustically square-law nonlinear medium and then the optical processing in the same solid-state cell. Technical advantage of this approach lies in providing a direct multi-channel parallel processing of ultra-high-frequency radio-wave signals with the resolution power exceeding 104. This algorithm can be realized on a basis of exploiting a large-aperture effective acousto-optical cell, which operates in the Bragg regime and performs the ultra-high-frequency co-directional collinear acoustic wave heterodyning. The general concept and basic conclusions here are confirmed by proof-of-principle experiments with the specially designed cell of a new type based on a lead molybdate crystal.

Lung ultrasound: a new tool for the cardiologist
Luna Gargani
Cardiovascular Ultrasound , 2011, DOI: 10.1186/1476-7120-9-6
Abstract: For many years ultrasound has not been employed for the evaluation of the lung [1]. All diagnostic ultrasound methods are based on the principle that ultrasound is reflected by an interface between media with different acoustic impedance. In normal conditions, with aerated lungs, the ultrasound beam finds the lung air and no image is visible, because no acoustic mismatch may reflect the beam, which is rapidly dissipated by air [2]. The only detectable structure is the pleura, visualized as a hyperechoic horizontal line, moving synchronously with respiration (see additional file 1). When the air content decreases - as in pulmonary edema, pulmonary fibrosis, etc. - the acoustic mismatch needed to reflect the ultrasound beam is created, and some images appear. In the presence of extravascular lung water (EVLW), the ultrasound beam finds subpleural interlobular septa thickened by edema. The reflection of the beam creates some comet-tail reverberation artifacts, called B-lines or ultrasound lung comets. A B-line is a discrete, laser-like, vertical, hyperechoic image, that arises from the pleural line, extends to the bottom of the screen without fading, and moves synchronously with respiration. Multiple B-lines are the sonographic sign of lung interstitial syndrome, and their number increases along with decreasing air content (see additional file 2). When the air content is further decreased, such as in lung consolidations, the acoustic window on the lung becomes completely open, and the lung may be directly visualized as a solid parenchyma, as the liver or the spleen (figure 1). Consolidations may be then measured and followed-up.There are some anectodical reports on B-lines since the eighties [3,4]. In 1994, Targetta firstly described the presence of B-lines in diseased lungs [5]. But it was Daniel Lichtenstein, a French intensivist, who established for the first time the 2 main structural correlates of B-lines, comparing ultrasound findings with chest computed tomograp
Células-tronco: pesquisa básica em saúde, da ética à panacéia
Luna, Naara;
Interface - Comunica??o, Saúde, Educa??o , 2007, DOI: 10.1590/S1414-32832007000300013
Abstract: even though stem cell therapies are still under experimentation, the media has represented them as a panacea that would cure all diseases. this fact secured the authorization for using human embryos as research material. therapies include manipulation of human material in tissue bioengineering, suggesting a representation of the body as a factory. this article describes stem cell research projects being carried out in the health sciences center of a higher education institution, focusing on field organization and on the system of values underlying scientific activity. researchers at different levels were interviewed about perspectives on, and implications of, their research in order to analyze the discourse of the projects' participants. experiments with adult stem cells enjoyed wide support, while the use of human embryos was disputed. the foundations of those arguments were sought in their relation both to the structure of the scientific field and to the researchers' religious background.
Maternidade desnaturada: uma análise da barriga de aluguel e da doa??o de óvulos
Luna, Naara;
Cadernos Pagu , 2002, DOI: 10.1590/S0104-83332002000200010
Abstract: this article discusses social representations of two practices related to the new reproductive technologies or assisted reproduction techniques. during in vitro fertilization, the transfer procedure of a woman's fertilized egg to another woman separates genetic motherhood from gestational motherhood. two practices relate to that: in egg donation the pregnant woman is considered the mother, while in surrogate gestational motherhood the mother is the egg donor or the woman who planned the gestation. the focus is in the analysis of the representations of egg donation and surrogate motherhood in juridical discourse and in texts from the brazilian press, considering also ethnographic articles. the opposition between nature and culture is a key for understanding the different reception of these practices.
Natureza humana criada em laboratório: biologiza??o e genetiza??o do parentesco nas novas tecnologias reprodutivas
Luna, Naara;
História, Ciências, Saúde-Manguinhos , 2005, DOI: 10.1590/S0104-59702005000200009
Abstract: new reproductive technologies or assisted reproduction are procedures that make procreation possible without sexual relations, the most well-known being artificial insemination and in vitro fertilization ('test-tube' babies). use of these new techniques raises the issue of the genetization of kinship ties, in contrast with adoption or procedures involving the donation of gametes (eggs and sperms) and embryos. based both on ethnographic research with users and professionals in assisted reproduction and also on bibliographic research, the article discusses the concepts of human nature implied in the biologization and genetization of kinship through these new reproductive technologies.
Pesquisas com células-tronco: um estudo de caso sobre a dinamica de um segmento do campo científico
Luna, Naara;
História, Ciências, Saúde-Manguinhos , 2012, DOI: 10.1590/S0104-59702012000100004
Abstract: based on a case study conducted at a public institution for higher education, the article investigates the dynamics of the scientific field of stem cell research. basic research projects with adult and embryonic stem cells (experiments in cell culture or an animal model) and tissue bioengineering were surveyed. fieldwork included ethnographic observation and interviews with researchers (graduate students and professors). project researchers were observed to be part of a scientific network displaying a marked division of labor and workflows of material and symbolic resources. a dynamic of alliances and exchanges was found to underlie collaborative relations between peers and students. when recapping the history of stem cell research at the institute, interviewees showed the organization of the field.
A personaliza??o do embri?o humano: da transcendência na biologia
Luna, Naara;
Mana , 2007, DOI: 10.1590/S0104-93132007000200005
Abstract: this article examines ideas concerning the human embryo and foetus present in the discourse of professional staff working in human reproductive medicine and infertility services, as well as texts published in the mainstream press. it focuses on the debate concerning the status of the embryo outside the body, in particular, the polemic surrounding the use of human embryos as research material for obtaining stem cells, an area of scientific investigation that raises the hope of cures for a wide range of diseases. this debate points to situations of 'social drama' or controversy that reveal critical questions for the constitution of society. here ideas concerning the human embryo and foetus tend either to attribute or deny them personhood. based on biological descriptions, but invoking both scientific and religious discourses, these arguments expose some of the contemporary values of modern western cosmology.
Religiosidade no contexto das terapias com células-tronco: uma investiga??o comparativa entre pesquisadores "iniciantes e iniciados" e seus pacientes
Luna, Naara;
Religi?o & Sociedade , 2008, DOI: 10.1590/S0100-85872008000200008
Abstract: experimental therapies with stem cells have waken public interest due to expectations of miraculous healings. the article analyses representations and religious commitment of people involved in different experimental protocols of cellular therapy: patients, their families and researchers of several levels. fieldwork took place in a higher education institution. the objective is to compare the positions of patients and researchers and also inside the researchers group (according to researcher's educational level) regarding: present religious commitment and previous background and their reactions about human embryo research. catholic church opposes the use of human embryos as research material and other religious confessions debate this subject. the paper also examines representations of cure and miracle related to stem cells.
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