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匹配条件: “Thanka J” ,找到相关结果约297226条。
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Extramedullary relapse of acute lymphoblastic leukemia in breast: A rare presentation
Thanka J,Krishnarathinam K,Rajendiran S
Indian Journal of Pathology and Microbiology , 2010,
Abstract: Unusual sites of relapses following allogenic hematopoietic stem cell transplantation (HSCT) for acute lymphoblastic leukemia (ALL) are rarely reported. Our report describes a thirty-two-year old female, who developed extramedullary (EM) breast relapse after allogenic HSCT for pre B cell Philadelphia chromosome negative ALL. She had no evidence of leukemia in her marrow demonstrating 100% full donor chimerism, while she had ALL relapse in her breast.
Effect of hydroalcoholic extract of aerial parts of Leucas aspera (Willd.) link on inflammatory markers in complete freund′s adjuvant induced arthritic rats
Kripa K,Chamundeeswari D,Thanka J,Reddy C
International Journal of Green Pharmacy , 2010,
Abstract: The plant Leucas aspera is claimed to possess anti-inflammatory and anti-rheumatic potential by traditional practitioners. The aim of this study is to validate the traditional claim. The hydroalcoholic extract of aerial parts of L. aspera (HAELA) was orally tested at a dose of 100 mg/kg bodyweight for anti-arthritic effect in adjuvant-induced arthritic rats. Group I rats served as vehicle control group [0.2% carboxyl methyl cellulose (CMC) p.o.]. The test groups were injected with 0.1 ml of complete Freund′s adjuvant into the subplantar region of right hind paw. Group II animals served as disease control, while the group III and group IV arthritic rats were treated with standard drug diclofenac sodium (0.3 mg/kg) and HAELA (100 mg/kg) for 21 days. Activities of inflammatory markers such as tumour necrosis factor-α, C-reactive protein, interleukin-2, cathepsin D and antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) were estimated in plasma/haemolysate and tissue of control and arthritic animals. Histopathological analysis of knee joints was also performed. Statistical analysis of the biochemical parameters was performed by one way analysis of variance (ANOVA) using SPSS software package. Results were expressed as mean±SEM for six rats in each group. P<0.05 was considered to be significant. HAELA showed significant anti-inflammatory (P<0.001) and antioxidant activity (P<0.001) at the specified dose. It did not show mortality up to 2000 mg/kg body weight. Histopathological studies confirmed cartilage regeneration and near normal joint in HAELA treated rats. It can thus be concluded that HAELA possesses significant antioxidant and anti-arthritic potential.
Splenic hamartoma: A rare vascular space occupying lesion of the Spleen
Sankar Subramanian,Thanka J,Jagdishchandrabose Subbaraj,Rajendran S
Indian Journal of Pathology and Microbiology , 2011,
Abstract:
Ductal carcinoma in a multiple fibroadenoma: Diagnostic inaccuracies
Rao Shalinee,Latha P,Ravi A,Thanka J
Journal of Cancer Research and Therapeutics , 2010,
Abstract: We present the diagnostic inaccuracies encountered in a case of multiple fibroadenoma with malignant transformation. A 30-year-old lady presented with lump in the right breast of one month duration which on clinical examination, X-ray mammogram, sonomammogram were suggestive of multiple fibroadenomas. Fine needle aspiration cytology of the largest lump revealed features of malignancy and a core biopsy showed pleomorphic cells that could not be categorized. Due to the clinical, radiological and pathological diagnostic ambiguity, lumpectomy was performed and frozen section showed features of only conventional fibroadenoma. Representative bits on routine processing showed only features of fibroadenoma. Hence, complete submission of all lumps was done, which revealed fibroadenoma with invasive ductal carcinoma in one. Patient underwent modified radical mastectomy which showed multiple fibroadenomas, focal fibrocystic disease with a focus of residual invasive tumor and metastatic deposit in one axillary lymph node. This case report highlights the diagnostic challenges in detecting malignancy in fibroadenoma and a need for extensive tissue sampling in multiple fibroadenomas to detect the rare occurrence of carcinoma.
Exploring fracture risk factors among Omani women: Implications for risk assessment  [PDF]
Melba Sheila D’Souza, Chandrani Isac, Ramesh Venkatesaperumal, Anandhi Amirtharaj, Anitha Thanka, Shreedevi Balachandran, Huda Al Noumani
Open Journal of Nursing (OJN) , 2012, DOI: 10.4236/ojn.2012.24054
Abstract: Osteoporosis is common among postmenopausal women, giving rise to morbidity and diminishing the quality of life. There is lack of information about the risk factors of Osteoporosis among local Omani women. The aim was to explore the risk factors of Osteoporosis among Omani women using a Modified Fracture Risk Assessment Tool. This is an exploratory research design using a simple random sampling. A pilot study was conducted among 35 local Omani women from the Muscat region, who completed the validated and reliable Modified Fracture Risk Assessment Tool (MFRAT). Bone Mineral Density (BMD) was measured among 11 women at moderate-high risk based on MFRAT. The data was analyzed using inferential statistics. Fourteen Omani women were at moderate-high risk for Osteoporotic fracture due to factors related premenopausal, Vitamin D deficiency, increased parity, increased lactation period and sedentary lifestyle. Among these five women had low BMD and required early intervention and support. Determinants of Osteoporosis can be assessed among premenopausal Omani women with a specific risk assessment tool. There is a need to construct a culturally sensitive risk assessment tool for Omani women for early screening and detection of Osteoporosis. Nurses can identify, provide intervention and education for Omani women at-risk of fracture.
New components of the mercury’s perihelion precession  [PDF]
J. J. Smulsky
Natural Science (NS) , 2011, DOI: 10.4236/ns.2011.34034
Abstract: The velocity of perihelion rotation of Mercury's orbit relatively motionless space is computed. It is prove that it coincides with that calculated by the Newtonian interaction of the planets and of the compound model of the Sun’s rotation.
Simple General Purpose Ion Beam Deceleration System Using a Single Electrode Lens  [PDF]
J. Lopes, J. Rocha
World Journal of Engineering and Technology (WJET) , 2015, DOI: 10.4236/wjet.2015.33014
Abstract: Ion beam deceleration properties of a newly developed low-energy ion beam implantation system were studied. The objective of this system was to produce general purpose low-energy (5 to 15 keV) implantations with high current beam of hundreds of μA level, providing the most wide implantation area possible and allowing continuously magnetic scanning of the beam over the sample(s). This paper describes the developed system installed in the high-current ion implanter at the Laboratory of Accelerators and Radiation Technologies of the Nuclear and Technological Cam-pus, Sacavém, Portugal (CTN).
Constraints on velocity anisotropy of spherical systems with separable augmented densities
J. An
Physics , 2011, DOI: 10.1088/0004-637X/736/2/151
Abstract: If the augmented density of a spherical anisotropic system is assumed to be multiplicatively separable to functions of the potential and the radius, the radial function, which can be completely specified by the behavior of the anisotropy parameter alone, also fixes the anisotropic ratios of every higher-order velocity moment. It is inferred from this that the non-negativity of the distribution function necessarily limits the allowed behaviors of the radial function. This restriction is translated into the constraints on the behavior of the anisotropy parameter. We find that not all radial variations of the anisotropy parameter satisfy these constraints and thus that there exist anisotropy profiles that cannot be consistent with any separable augmented density.
On the augmented density of a spherical anisotropic dynamic system
J. An
Physics , 2010, DOI: 10.1111/j.1365-2966.2011.18324.x
Abstract: This paper presents a set of new conditions on the augmented density of a spherical anisotropic system that is necessary for the underlying two-integral phase-space distribution function to be non-negative. In particular, it is shown that the partial derivatives of the Abel transformations of the augmented density must be non-negative. Applied for the separable augmented densities, this recovers the result of van Hese et al. (2011).
Fractional calculus, completely monotonic functions, a generalized Mittag-Leffler function and phase-space consistency of separable augmented densities
J. An
Physics , 2012,
Abstract: Under the separability assumption on the augmented density, a distribution function can be always constructed for a spherical population with the specified density and anisotropy profile. Then, a question arises, under what conditions the distribution constructed as such is non-negative everywhere in the entire accessible subvolume of the phase-space. We rediscover necessary conditions on the augmented density expressed with fractional calculus. The condition on the radius part R(r^2) -- whose logarithmic derivative is the anisotropy parameter -- is equivalent to R(1/w)/w being a completely monotonic function whereas the condition on the potential part is stated as its derivative up to the order not greater than 3/2-b being non-negative (where b is the central limiting value for the anisotropy parameter). We also derive the set of sufficient conditions on the separable augmented density for the non-negativity of the distribution, which generalizes the condition derived for the generalized Cuddeford system by Ciotti & Morganti to arbitrary separable systems. This is applied for the case when the anisotropy is parameterized by a monotonic function of the radius of Baes & Van Hese. The resulting criteria are found based on the complete monotonicity of generalized Mittag-Leffler functions.
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