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Search Results: 1 - 10 of 325272 matches for " Thanikachalam S "
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Locally aggressive orbital fibrous histiocytoma
Bajaj Mandeep,Sethi Anita,Kashyap Seema,Thanikachalam S
Indian Journal of Ophthalmology , 2004,
Abstract: We report a rare presentation of a massive, locally aggressive, fibrous histiocytoma of the orbit. The importance of histopathological grading and appropriate management are highlighted.
Evaluation of subjective and objective cyclodeviation following oblique muscle weakening procedures
Sharma Pradeep,Thanikachalam S,Kedar Sachin,Bhola Rahul
Indian Journal of Ophthalmology , 2008,
Abstract: Purpose: To evaluate the subjective and objective cyclodeviational changes following different weakening procedures on superior and inferior oblique muscles Design: Comparative case series Materials and Methods: In a prospective institution based study, 16 cases of A pattern horizontal strabismus having superior oblique overaction were randomized to superior oblique weakening procedures: either silicon expander or translational-recession. Similarly, 20 cases of V pattern horizontal strabismus with inferior oblique overaction were randomized for inferior oblique weakening procedures: either 10 mm Fink′s recession or modified Elliot and Nankin′s anteropositioning. Cyclodeviation was assessed subjectively with the synoptophore and objectively using the fundus photograph before surgery and 3 months postoperatively. Change in cyclodeviation was measured by subjective and objective methods. The index of surgical effect (ISE) was defined as the net torsional change postoperatively. Results: The difference between the extorsional change induced by the two superior oblique procedures, silicone expander (-6°) and translational recession (-11.3°), was statistically significant (P=0.001). Translational recession caused more extorsional change (ISE=296%) than silicone expander surgery (ISE=107%). The two inferior oblique weakening procedures, Fink′s recession (+2.5°) and modified Elliot and Nankin′s anteropositioning (+4.7°) produced equitable amount of intorsional shift with no statistical difference (P=0.93). Objective measurements were significantly more than the subjective measurements. Conclusions: Different weakening procedures on oblique muscles produce different changes in cyclodeviation, which persists even up to 3 months. Subjective cyclodeviation is less than the objective measurements indicating partial compensation by sensorial adaptations.
A New Process of Color Images Recognition by Using ART-1 Neural Network
R. Thilepa,M. Thanikachalam
Computer and Information Science , 2010, DOI: 10.5539/cis.v4n1p217
Abstract: In this paper ART1 neural network algorithm is used for recognition of color images which speeds up the process of Image processing and its recognition process. But, generally Adaptive Resonance Theory-1(ART-1) network is used only for processing binary digits, but in this paper it may also be used for image recognition. The given fact limits the loss of information as a result, two different colors in which inside one original image can be represented as a same value of binary color during recognition. These mistakes are overcome by our image recognition method here.This method is very attractive because of its low computational overhead, improved performance comparatively than other networks with less number of neurons. Experimental results are given finally which are encouraging in this paper.
A Rare Case Presentation of Meckel’s Diverticulum with Situs Inversus Totalis
Yazhini.V,Kannan Thanikachalam
International Journal of Collaborative Research on Internal Medicine & Public Health , 2011,
Abstract: Situs inversus, a rare congenital condition, is a complete mirror image of the thoracic and abdominal viscera, in which the positions of major visceral organs are reversed. Here, we report a case of a 6 year old boy who presented with abdominal pain in both the iliac fossae, fever and vomiting. Imaging studies showed situs inversus totalis and a provisional diagnosis of acute appendicitis was made and a possibility of meckel’s diverticulitis was suspected. A final diagnosis of meckel’s diverticulitis was made during emergency laparotomy. This case report is being presented because of its rare occurrence.
FABRIC FAULT DETECTION USING IMAGE PROCESSING WITH ATMEL MICROCONTROLLER
R.THILEPA,,M.THANIKACHALAM
International Journal of Engineering Science and Technology , 2010,
Abstract: In this paper it is explained how a faulty fabric image is processed through a microcontroller. If there is any fault how it is identified through this ATMEL microcontroller by the circuit operation. For programming the controller Atmel program is used. In addition to that a stepper motor is connected in the output. This motor operates if there is no fault and fails if the fault is identified. This can be implemented in states like Tamilnadu so that the textile field’s income may be increased in an enormous way which in turn raises the country’s income [7].
A Paper on Automatic Fabrics Fault Processing Using Image Processing Technique In MATLAB
R.Thilepa,M.Thanikachalam
Signal & Image Processing , 2011,
Abstract: The main objective of this paper is to elaborate how defective fabric parts can beprocessed using Matlab with image processing techniques. In developing countries like Indiaespecially in Tamilnadu, Tirupur the Knitwear capital of the country in three decades yields amajor income for the country. The city also employs either directly or indirectly more than 3lakhs of people and earns almost an income of 12, 000 crores per annum for the country in pastthree decades [2]. To upgrade this process the fabrics when processed in textiles the fault presenton the fabrics can be identified using Matlab with Image processing techniques. This imageprocessing technique is done using Matlab 7.3 and for the taken image, Noise Filtering,Histogram and Thresholding techniques are applied for the image and the output is obtained inthis paper. This research thus implements a textile defect detector with system visionmethodology in image processing.
Goldenhar′s sequence with associated juvenile glaucoma in Turner′s syndrome
Rao Vasudev,Kaliaperumal Subashini,Subramanyan Thanikachalam,Rao Kotapalli
Indian Journal of Ophthalmology , 2005,
Abstract:
Reduced exposure of imatinib after coadministration with acetaminophen in mice
Nassar Inthisham,Pasupati Thanikachalam,Judson John,Segarra Ignacio
Indian Journal of Pharmacology , 2009,
Abstract: Purpose: Imatinib is an efficacious drug against chronic myeloid leukemia (CML) and gastrointestinal stromal tumor (GIST) due to selective inhibition of c-KIT and BCR-ABL kinases. It presents almost complete bioavailability, is eliminated via P450-mediated metabolism and is well tolerated. However, a few severe drug-drug interactions have been reported in cancer patients taking acetaminophen. Materials and Methods: Male ICR mice were given 100 mg/kg single dose of imatinib orally or imatinib 100 mg/kg (orally) coadministered with acetaminophen intraperitoneally (700 mg/kg). Mice were euthanized at predetermined time points, blood samples collected, and imatinib plasma concentration measured by HPLC. Results: Imatinib AUC 0-12 was 27.04 ± 0.38 mg h/ml, C max was 7.21 ± 0.99 mg/ml and elimination half-life was 2.3 hours. Acetaminophen affected the imatinib disposition profile: AUC 0-12 and C max decreased 56% and 59%, respectively and a longer half-life was observed (5.6 hours). Conclusions: The study shows a pharmacokinetic interaction between acetaminophen and imatinib which may render further human studies necessary if both drugs are administered concurrently to cancer patients.
Non-Isothermal Decomposition of 2-(2-Hydroxybenzylideneamino)-3-phenylpropanoic Acid in Nitrogen Atmosphere
M. Vennila,G. Manikandan,V. Thanikachalam,J. Jayabharathi
Journal of Chemistry , 2011, DOI: 10.1155/2011/235090
Abstract:
Enantiospecific pharmacokinetic studies on ketoprofen in tablet formulation using indirect chiral HPLC analysis
Kannappan Valliappan,Kamarajan Kannan,Thanikachalam Sivakumar,Rajappan Manavalan
Journal of Applied Biomedicine , 2006,
Abstract: The present study was undertaken to evaluate the possibility of chiral discrimination in the release ofenantiomers of ketoprofen (KT) in tablet form and, in turn, the bioavailability of the individualenantiomers, using the rabbit as a model. The enantiomeric concentration of KT in plasma wasdetermined using a customized chiral HPLC analysis. First the plasma concentration-time profile wasestablished for pure (±) KT in order to assess the extent of chiral discrimination. Subsequently the tabletformulation (Rhofenid-100mg) was administered, at a dose equivalent to 10 mg/kg, to assess theenantiospecific bioavailability of KT enantiomers in the rabbit following the same protocol as followedfor the pure KT. In vivo studies revealed that the bioavailability of S-KT is higher than that of the Renantiomer,after oral dosing with both KT-tablet and KT-pure. But the degree of chiral discrimination ismore pronounced and more statistically significant in the case KT formulation as reflected by theenantioselective pharmacokinetic data. The observations presented in this article further emphasize thesignificance of differentiating between enantiomers of chiral drugs when assessing bioavailability andcorrelating efficiency with drug concentration. The study opens up a new avenue to the design ofstereoselective dosage forms.
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