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Search Results: 1 - 5 of 5 matches for " Thaigarajan Nambirajan "
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Outcome of Glansectomy and Skin Grafting in the Management of Penile Cancer
Hugh F. O'Kane,Ajay Pahuja,K. J. Ho,Ali Thwaini,Thaigarajan Nambirajan,Patrick Keane
Advances in Urology , 2011, DOI: 10.1155/2011/240824
Abstract: Purpose. To report outcome data for patients with penile cancer treated surgically with glansectomy and skin grafting. Materials and Methods. We retrospectively reviewed data on all patients undergoing surgical management of penile cancer by a single surgeon between 1998 and 2008. Outcomes in patients who underwent glansectomy and skin grafting were analysed. Results. Between 1998 and 2008 a total of 25 patients with a mean age 60 (39–83) underwent glansectomy and skin grafting. Six patients had carcinoma in situ (CIS); the stage in the remaining patients ranged from T1G1 to T3G3. Mean followup for patients was 28 months (range 6–66). Disease specific survival was 92% with 2 patients who had positive nodes at lymph node dissection developing groin recurrence. One patient developed a local recurrence requiring a partial penectomy. Conclusions. Penile preserving surgery with glansectomy and skin grafting is a successful technique with minimal complications for local control of penile carcinoma arising on the glans. Careful followup to exclude local recurrence is required. 1. Introduction Penile cancer is an uncommon malignancy in the industrialized world, particularly in Europe and in the USA with an incidence of less than 1 per 100?000 of the male adult population. In contrast to this, the incidence in some parts of the developing world is as high as 19 per 100?000 per year [1]. More than 95% of penile cancers are primary squamous cell carcinomas with other uncommon histological types including melanoma, sarcoma, and basal cell carcinomas. Historically, the surgical management of the primary lesion in penile carcinoma has meant either partial or radical penectomy. Oncologically, radical surgical excision has stood the test of time, with excellent local control. These operations are however often mutilating and associated with urinary and sexual dysfunction as well as significant psychological morbidity [2]. In an attempt to reduce the negative impact of radical surgery and retain functional penile length, a variety of therapeutic strategies have been developed particularly for the management of more distal lower-grade cancers. The obvious risk is always that there will be compromise of local oncological control. Oncological outcomes of “penile preserving” surgical techniques should always, if possible, be measured against the gold standard of radical excision. Randomised trials are next to impossible in such an uncommon disease and although widely practiced and results are encouraging, only a small number of centres have published their outcome data on
Balasubramanian Thaigarajan,Venkatesan Ulaganathan
Otolaryngology Online Journal , 2013,
Abstract: Nose is the most prominent part of the face, hence it is likely to be the most common structure to be injured in the face. Although fractures involving the nasal bones are very common, it is often ignored by the patient. Patients with fractures of nasal bone will have deformity, tenderness, haemorrhage, edema, ecchymosis, instability, and crepitation. These features may be present in varying combinations. This article discusses the pathophysiology of these fractures, role of radiography and ultrasound in their diagnosis and their management.
Identifying Influential Entries in a Matrix
Abhisek Kundu,Srinivas Nambirajan,Petros Drineas
Computer Science , 2013,
Abstract: For any matrix A in R^(m x n) of rank \rho, we present a probability distribution over the entries of A (the element-wise leverage scores of equation (2)) that reveals the most influential entries in the matrix. From a theoretical perspective, we prove that sampling at most s = O ((m + n) \rho^2 ln (m + n)) entries of the matrix (see eqn. (3) for the precise value of s) with respect to these scores and solving the nuclear norm minimization problem on the sampled entries, reconstructs A exactly. To the best of our knowledge, these are the strongest theoretical guarantees on matrix completion without any incoherence assumptions on the matrix A. From an experimental perspective, we show that entries corresponding to high element-wise leverage scores reveal structural properties of the data matrix that are of interest to domain scientists.
International Journal of Engineering Science and Technology , 2011,
Abstract: This paper aims to assess the performance of three depots of a public sector bus passenger transport company. The performance data have been collected from the real users. The feedback obtained from thedepot managers are predominantly quantitative whereas the feedback information obtained from the regular passengers are of purely qualitative basis. These quantitative and qualitative data has beenanalyzed with multi-criteria decision making model. The Technique for Order Preference by Similarity to Ideal Solution method for decision making problems with Fuzzy data (FTOPSIS) and Fuzzy AnalyticalHierarchy Process (FAHP) has been used for the managers’ feedback and the One-way Analysis of Variance (ANOVA) has been used for the passengers’ information. The values obtained have been combined to obtain the final results. The overall systematic algorithm for determining the best performing depot has been illustrated in step by step basis for continuous improvement.
Analysis of Pull-in Behavior of Electrostatic MEMS Actuators for Optical Switching Applications
M. Maheswaran,M. Nambirajan,Uppari Chaitanya Chandra Yadav,Har Narayan Upadhyay
Journal of Applied Sciences , 2012,
Abstract: Micro Electromechanical Systems (MEMS) actuators experience pull-in instability in their actuation range. MEMS actuating elements are thin parallel plate capacitor electrodes separated with air gap. The electrodes are fabricated from silicon as substrate layer and gold /aluminum layer as functional layer for reflecting laser beam in optical switching application. When the top electrode is attracted towards bottom electrode, as it crosses one third distance of the gap between the electrodes, it undergoes pull-in/snap-down with bottom electrode. This condition severely limits the device operating range. These devices are operated either analog or digital mode for positioning of the top electrode. The plate electrodes actuated in tilting mode or bending mode and they are typically torsional structures or fixed-fixed structures. This paper provides theoretical pull-in analysis for the static behavior of a optical switch model. It is derived from analytical modeling of the parallel plate type with fixed-fixed structural end conditions. The effect of dielectric layer thickness is taken into account for predicting the pull-in voltage. During the piston mode actuation cycle, when the threshold (pull-in) voltage is reached, the switch is in the bent or ON state due to electrostatic repulsion/attraction and for the no voltage condition it is in the parallel or OFF state. The pull-in hysteresis behavior of the multilayered micro-actuator bending beam model is analyzed for the variation in thickness of dielectric material. In this paper, the critical role of different dielectric layer materials in bringing down the static pull-in voltage is discussed.
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