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Search Results: 1 - 10 of 1517 matches for " Tetsuo Harada "
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Effects of evening light conditions on salivary melatonin of Japanese junior high school students
Tetsuo Harada
Journal of Circadian Rhythms , 2004, DOI: 10.1186/1740-3391-2-4
Abstract: Effects of exposure to the bright light (2000 lux) from fluorescent light bulbs during a period of three hours from 19:30 to 22:30 in one evening were examined on evening salivary melatonin concentrations from 19:45 to 23:40. The control group was exposed to dim light (60 lux) during these three hours. Both the dim light control group [DLCG] and the bright light experimental group [BLEG] consisted of two female and three male adolescent participants aged 14–15 y.The salivary melatonin level increased rapidly from 3.00 pg/ml at 21:45 to 9.18 pg/ml at 23:40 in DLCG, whereas it remained at less than 1.3 pg/ml for the three hours in BLEG. Melatonin concentration by BLEG at 22:30 of the experimental day was lower than that at the same time on the day before the experimental day, whereas it was significantly higher in the experimental day than on the day before the experimental day in DLCG.Bright lights of 2000 lux and even moderate lights of 200–300 lux from fluorescent light bulbs can inhibit nocturnal melatonin concentration in adolescents. Ancient Japanese lighting from a traditional Japanese hearth, oil lamp or candle (20–30 lux) could be healthier for children and adolescents because rapid and clear increase in melatonin concentration in blood seems to occur at night under such dim light, thus facilitating a smooth falling into night sleep.Night sleep duration of Japanese children aged 10–18 y has become shorter by one hour during the last 30 years in Japan [1]. The so called "24-hour society", which is currently in progress in Japan, seems to change environmental conditions surrounding children. For example, mobile phones are used by more than 90 % of university students and more than 30% of junior high school students living in the urban area of Kochi city (33°N) [2]. Students can communicate with their colleagues even in the middle of the night with mobile phones. Frequent or long-time (more than 30 min) usage of the mobile phone makes university and junior high
Role of Antimicrobial Selective Pressure and Secondary Factors on Antimicrobial Resistance Prevalence in Escherichia coli from Food-Producing Animals in Japan
Kazuki Harada,Tetsuo Asai
Journal of Biomedicine and Biotechnology , 2010, DOI: 10.1155/2010/180682
Abstract: The use of antimicrobial agents in the veterinary field affects the emergence, prevalence, and dissemination of antimicrobial resistance in bacteria isolated from food-producing animals. To control the emergence, prevalence, and dissemination of antimicrobial resistance, it is necessary to implement appropriate actions based on scientific evidence. In Japan, the Japanese Veterinary Antimicrobial Resistance Monitoring System (JVARM) was established in 1999 to monitor the antimicrobial susceptibility of foodborne and commensal bacteria from food-producing animals. The JVARM showed that the emergence and prevalence of resistant Escherichia coli were likely linked to the therapeutic antimicrobial use in food-producing animals through not only direct selection of the corresponding resistance but also indirect selections via cross-resistance and coresistance. In addition, relevant factors such as host animals and bacterial properties might affect the occurrence and prevalence of antimicrobial-resistant E. coli under the selective pressure from antimicrobial usage. This paper reviews the trends in antimicrobial resistance in E. coli and consumption of antimicrobials agents in Japan and introduces the relationship between antimicrobial usage and prevalence of antimicrobial-resistant bacteria, from food-producing animals under the JVARM program. In this paper, we will provide the underlying information about the significant factors that can help control antimicrobial resistance in bacteria in veterinary medicine.
PTSD Score, Circadian Typology and Sleep Habits of People who Experienced the Great Hanshin-Awaji Earthquake 17 Years Ago  [PDF]
Hiroko Kuroda, Kai Wada, Hitomi Takeuchi, Tetsuo Harada
Psychology (PSYCH) , 2013, DOI: 10.4236/psych.2013.42015

This study aims to determine the relationship between Post Traumatic Stress Disorder (PTSD) and current circadian typology and sleep habits of adults who experienced the Great Hanshin-Awaji Earthquake (on 17th January 1995) after becoming adults. An integrated questionnaire was administered in August, 2011 to 467 people aged 38 - 92 (mean age: 64.8 years) in Hyogo Prefecture, Japan, with responses received from 223 people (females: 142, males: 78, unknown: 3). The questionnaire consisted of basic questions about attributes such as age and sex, questions on sleep habits and sleep quality (Subjective Sleep Quality Scale), the Torsvall-?kerstedt Diurnal Type Scale and the Impact of Event Scale-Revised (IES-R) which dealt with PTSD scores. The participants were divided into a High Damage Group (HDG) and Low Damage Group (LDG) based on public statistical information on the extent of damage to buildings and number of casualties in the smaller districts of Kobe City in which participants experienced the disaster. HDG participants exhibited significantly higher IES-R scores than LDG participants (p = .002). Only in HDG participants, there was significantly negative correlation between Diurnal-Type scale scores and IES-R scores (high PTSD scores correlated with greater evening type [low scores of Diurnal-Type scale]) (p = .001) (p = .920 in LDG participants). In both the HDG and LDG, there was a significant positive correlation between the Subjective Sleep

Epidemiological Studies on the Relationship between PTSD Symptoms and Circadian Typology and Mental/Sleep Health of Young People Who Suffered a Natural Disaster, Great Hanshin-Awaji Earthquake  [PDF]
Kai Wada, Hiroko Kuroda, Miyo Nakade, Hitomi Takeuchi, Tetsuo Harada
Natural Science (NS) , 2014, DOI: 10.4236/ns.2014.65035

This study aims, first, to determine the relationship between Post Traumatic Stress Disorder (PTSD) and current circadian typology and sleep habits of adults who experienced the Great Hanshin-Awaji Earthquake in their childhood in January 1995. An integrated questionnaire was administered to 275 university students (females: 173, males: 93, unknown: 9) aged 19 - 37 (mean age: 21.9 years) in Hyogo Prefecture, Japan. The questionnaire consisted of basic questions about attributes, questions on sleep habits and sleep quality (Monroe’s sleep quality index), the Torsvall-?kerstedt Diurnal Type Scale and the Impact of Event Scale-Revised (IES-R) to obtain PTSD scores. Participants who scored 25 or more in the IES-R were placed in a high-traumatic group (HTG) and those who scored less than 25 were placed in a low-traumatic group (LTG). HTG participants exhibited significantly worse sleep quality than LTG participants (p < 0.001). Although there was no significant difference in sleep latency (p > 0.05), HTG participants woke more frequently during sleep (p < 0.001) and had more difficulty falling asleep (p = 0.001) than LHG participants. Significantly more LTG participants fell asleep easily and slept deeply than HTG participants (p = 0.005, p = 0.011). Only among females, HTG participants were more evening-typed than LTG participants (p = 0.035). These results suggest that people who suffered a disaster in childhood and currently have PTSD have difficulty achieving high sleep quality. Evening-type lifestyles may reinforce the symptoms of PTSD. The study aims, second, to examine the effects of intervention for one month using a leaflet to promote the morning-typed life for persons who suffered natural disaster entitled “Go to bed early, Get up early and Do not forget to have a breakfast for getting three benefits!”. Only one person was over the cutoff point (between 24 and 25) before intervention. This high-traumatic person’s comprehensive sleep health tended to be improved through the intervention (p = 0.052). Such intervention to improve their quality of sleep and promote a morning-typed lifestyle may be an effective way to reduce PTSD symptoms.

Effects of Video Game Playing on the Circadian Typology and Mental Health of Young Czech and Japanese Children  [PDF]
Milada Krejci, Kai Wada, Miyo Nakade, Hitomi Takeuchi, Teruki Noji, Tetsuo Harada
Psychology (PSYCH) , 2011, DOI: 10.4236/psych.2011.27103
Abstract: The objective of this study is to examine the effects of video game playing on sleep-wake cycles and mental health of young Czech and Japan children. A cross-sectional survey with 497 Czech children (240 girls, 257 boys; mean age of 4.60 years; 49? - 51?N) and 599 Japanese children (314 girls, 285 boys: 3.79 years; 33?N) from 20 kindergartens and nursery schools. 20% and 30% of Czech and Japanese children had their own video game devices. Young children who played video games every day had later sleep and wake times (P < 0 .001) and were more evening-typed (P < 0.001) than those who did not every day in the both countries. The longer Czech children played video games per time, the later sleep and wake times were (P < 0.001). Czech children who played video games from 18:00 - 21:00 showed later sleep times and shorter sleep hours (P < 0.001) on weekdays than those who played at earlier times. Japanese children who played video games from 18:00 - 21:00 were more evening-typed and woke up later than those who played at earlier times (P < 0.001). Czech children who had their own video game devices had a higher frequency of anger than those who did not (P < 0.001). Ha- bitual video game playing in the evening may make children more evening-typed and it may also be speculated to make them more aggressive in both countries.
Change in reproductive and dispersal traits in the water strider, Aquarius paludum (Fabricius) and global warming  [PDF]
Tetsuo Harada, Takashi Shiraki, Shiho Takenaka, Takero Sekimoto, Kentaro Emi, Tomoya Furutani
Natural Science (NS) , 2013, DOI: 10.4236/ns.2013.51A024

This study aims to examine the following three hypotheses on the impact of global warming on the populations of the water strider, Aquarius paludum in the Kochi-Nankoku area (3330'N) of Kochi prefecture, Japan through the recent data collected in 2009-2011. 1) Has the generation number increased? 2) Has aestivation appeared in adults? 3) Have overwintering adults stopped dispersing between the water surface and overwintering lands-sites far away from water and, instead, overwintered on/near the shore? Sampling data showed that the number of generations may have increased from three (1989-2002 strains) and four (2004-2008) to five (2009-2011) per year in Kochi (33N). The ratio of adults having well developed flight muscles decreased from 45% in 1995 to 24% - 28% in 2009-2011 inoverwintering adults collected from the field in fall likely as a result of histolysis. “Mosaic-typed” wing morph group with long fore-wings and short hind-wings newly appeared in 2009-2011 in the Kochi-Nankoku overwintering populations. The mosaic-typed wings group cannot fly and the black and long fore wings might function as absorbing apparatus of sun-lights in the daytime of winter. Some overwintering adults seem to stop migrating between water bodies and overwintering sites on land far from the water bodies and overwinter, instead, near the shore. The use of Aquarius paludum as a biological indicator would be possible in the future, because this species can respond and change their reproductive and dispersal characteristics to the global change.

Effects of Makeup, Perfume and Skincare Product Usage and Hair Care Regimen on Circadian Typology, Sleep Habits and Mental Health in Female Japanesestudents Aged 18 - 30  [PDF]
Risa Nishihara, Kai Wada, Osami Akimitsu, Milada Krejci, Teruki Noji, Miyo Nakade, Hitomi Takeuchi, Tetsuo Harada
Psychology (PSYCH) , 2013, DOI: 10.4236/psych.2013.43028

Olfactory stimulation has been reported to trigger waking up during night sleep, and to affect the sympathetic nervous system and blood pressure of humans via the circadian clock system. Olfactory stimulation may promote better sleep health in Japanese students living in 24-hour society, but no studies have been done on this hypothesis. The purpose of this study is to make it clear what are the effects of makeup, perfume and skin care products on the circadian typology, sleep habits and mental health of female Japanese students aged 18 - 30 using an integrated questionnaire. Students who regularly used skin care products went to bed earlier on both weekdays and weekends and also got up earlier in the morning on weekdays than those who did not (p < 0.05). The students who wore makeup two or more days per week showed higher sleep quality than those who were makeup only one day a week or less (p < 0.05). The students who regularly carried out a hair care regimen showed a significantly lower frequency of becoming angry after a small trigger and of losing control due to anger than those who did not. Makeup, perfume and skin care products might be possible to be related to better sleep health for students. Moreover, hair care may help maintain mental health in female students. Makeup, perfume and skin care products might be implied to become chemical, mechanical and/or psychological stimuli as zeitgebers for circadian clock of students.

Effects of Cow Milk Intake at Breakfast on the Circadian Typology and Mental Health of Japanese Infants Aged 1 - 6 Years  [PDF]
Hitomi Takeuchi, Kai Wada, Kiyoko Kawasaki, Milada Krejci, Teruki Noji, Takahiro Kawada, Miyo Nakade, Tetsuo Harada
Psychology (PSYCH) , 2014, DOI: 10.4236/psych.2014.52027

Tryptophan intake at breakfast has been known to be effective on promoting better mental health and morning-typed life through serotonin and melatonin synthesis. For Japanese children, milk seems to be important resource for taking tryptophan at breakfast because of limited meal time in the morning. This study tries to show the effects of milk intake at breakfast on circadian typology and mental health of Japanese infants aged 1 - 6 years. An integrated questionnaire was administrated to 1100 infants aged 1 - 6 years attending nursery schools or kindergarten in June 2012. Seven hundred and forty participants (67.3%, 360 females and 380 males, mean age: 3.5 ± 1.4) answered the questionnaire. The questionnaire included questions on sleep habits, the diurnal type scale by Torsvall and ?kerstedt (1980), questions on mental health (anger and depression), and meals contents and time. Infants who took milk at breakfast showed 21.2 (±3.4, n = 537) of the diurnal type scale scores on average which tended to be higher (more morning-typed) than 20.7 (±3.5, n = 142) (p = 0.085) shown by those who did not take milk. Infants who took carbohydrate (or carbohydrate and protein resource) plus milk at breakfast were significantly morning-typed than those who took only carbohydrate (or carbohydrate and protein resource) (p < 0.001). Infants who took milk at breakfast tended to be less frequently depressed than those who did not (p = 0.098). Taking milk at breakfast might be effective to promote serotonin synthesis in the morning which could improve mental health directly and become “inner” zeitgeber for circadian clocks in infants.

An Efficient Synthesis of 2,3-Diaminoacid Derivatives Using Phosphine Catalyst  [PDF]
Yohei Oe, Hiroaki Kishimoto, Nahoko Sugioka, Daisuke Harada, Yukio Sato, Tetsuo Ohta, Isao Furukawa
International Journal of Organic Chemistry (IJOC) , 2014, DOI: 10.4236/ijoc.2014.43021
Abstract: Ethyl 2,3-diphthalimidoylpropanoate was effectively synthesized from ethyl propynoate with two equivalents of phthalimide catalyzed by triphenylphosphine in good yield. The choice of reaction media was important for selective synthesis of the desired 2,3-diaminocarboxylic acid derivatives. The reaction is considered to occur through a zwitterionic intermediate derived from the reaction of the α,β-unsaturated ester with triphenylphosphine.
Questionnaire Study on the Comparison among Circadian Typology, Sleep Habit, Physical and Mental Health and Meal Habit in Japanese University Athletes  [PDF]
Miyo Nakade, Hitomi Takeuchi, Takuya Uezato, Milada Krejci, Fujiko Tsuji, Takahiro Kawada, Teruki Noji, Tetsuo Harada
Psychology (PSYCH) , 2015, DOI: 10.4236/psych.2015.612153
Abstract: It has been pointed out that Japanese university students have several problems from psychological and social points of view due to their evening-typed life. For university athletes, evening-typed life is afraid to promote reduced quality of performance and high risk to be injured during training and match. This study tries to investigate the relationship among circadian typology, sleep habit, physical and mental health and meal habit from epidemiological view point. An integrated questionnaire was administrated to 120 men athletes attending university soccer club in November 2013 and 62 ones answered it correctly. The questionnaire included the diurnal type scale which is constructed by Torsvall & ?kerstedt (1980) and questions on sleep habits and mental health, SOC scale (SOC3- UTHS) and FFQ scale. Morning-typed students showed higher quality of sleep (p = 0.015) and they tended to have higher SOC scores (p = 0.071) than the other chrono-types. Evening-typed students took higher amount of carbohydrates than the other types (p = 0.048). Circadian typology might be related to not only sleep health but also the nutritional characteristics and psychological responses to social stress in Japanese university athletes.
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