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Search Results: 1 - 10 of 220485 matches for " Tessa C. Robson "
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Impacts of the Replacement of Native Woodland with Exotic Pine Plantations on Leaf-Litter Invertebrate Assemblages: A Test of a Novel Framework
Brad R. Murray,Andrew C. Baker,Tessa C. Robson
International Journal of Ecology , 2009, DOI: 10.1155/2009/490395
Abstract: We present an empirical comparison of invertebrate community structure between areas of undisturbed native eucalypt woodland and areas that have been cleared and replaced with plantations of exotic radiata pine (Pinus radiata). Implementation of a novel conceptual framework revealed that both insect (in autumn) and arachnid (in winter) assemblages demonstrated inhibition in response to the pine plantations. Species richness declines occurred in several taxonomic Orders (e.g., Hymenoptera, Blattodea, Acari) without compensated increases in other Orders in plantations. This was, however, a seasonal response, with shifts between inhibition and equivalency observed in both insects and arachnids across autumn and winter sampling periods. Equivalency responses were characterized by relatively similar levels of species richness in plantation and native habitats for several Orders (e.g., Coleoptera, Collembola, Psocoptera, Araneae). We propose testable hypotheses for the observed seasonal shifts between inhibition and equivalency that focus on diminished resource availability and the damp, moist conditions found in the plantations. Given the compelling evidence for seasonal shifts between categories, we recommend that seasonal patterns should be considered a critical component of further assemblage-level investigations of this novel framework for invasion ecology.
Is total colectomy for colorectal cancer contraindicated in elderly patients?
Grassia S,La Tessa C,Spiezia S,Romagnuolo R
BMC Geriatrics , 2011, DOI: 10.1186/1471-2318-11-s1-a24
A Review of Enrofloxacin for Veterinary Use  [PDF]
Tessa Trouchon, Sébastien Lefebvre
Open Journal of Veterinary Medicine (OJVM) , 2016, DOI: 10.4236/ojvm.2016.62006
Abstract: This review outlines the current knowledge on the use of enrofloxacin in veterinary medicine from biochemical mechanisms to the use in the field conditions and even resistance and ecotoxicity. The basics of biochemistry, the mechanisms of action and resistance and pharmacokinetics are presented. Then an overview of available veterinary products, their efficacy and their toxicity against target species, human and environment is provided.
Downregulation of Scar Fibroblasts by Antineoplastic Drugs: A Potential Treatment for Fibroproliferative Disorders  [PDF]
M. Georgina Uberti, Yvonne N. Pierpont, Rajat Bhalla, Karan Desai, Martin C. Robson, Wyatt G. Payne
Surgical Science (SS) , 2016, DOI: 10.4236/ss.2016.76037
Abstract: The various fibroproliferative disorders affecting humans have in common excess fibroblast activity and persistent overexpression or dysregulated activity of transforming growth factor beta (TGF-β). Cancer has many similar characteristics. Antineoplastic drugs can downregulate fibroblast activity and cytokine growth factors. This study evaluates the effect of six antineoplastic drugs on keloid and Dupuytren’s disease fibroblasts. Keloid, normal scar, Dupuytren’s affected palmar fascia, and normal palmar fascia fibroblasts were grown and seeded into Fibroblast Populated Collagen Lattices (FPCLs). The FPCLs were treated with one of six antineoplastic drugs or left untreated as controls. At 7 days, supernatants were extracted from all FPCLs and assayed for expression of Transforming Growth Factor beta (TGF)-β1 and TGF-β2. All six antineoplastic drugs significantly inhibited FPCL contraction in both fibroproliferative conditions compared with the untreated controls (p < 0.05). Similarly, TGF-β1 and TGF-β2 expression was downregulated in the supernatants of all FPCLs by the drug exposure. Cytotoxicity did not occur in these studies and was not the reason for the results. Although antineoplastic drugs can have significant side effects when given systemically, these results may be minimized when given to small areas involved in fibroproliferative scarring or when given topically or intralesionally. These in vitro results suggest that antineoplastic drugs may have a utility for treating various fibroproliferative disorders and warrant further investigation.
A Prospective, Within-Patient Controlled Study to Compare the Ability of the Non Adherent Drawtex? Hydroconductive Dressing to a Transparent Polyurethane Film Dressing (Standard of Care) on the Healing of Split-Thickness Skin Graft Donor Sites*  [PDF]
Barend H. Van den Bergh, Deirdré Kruger, Jonathan Kourie, Steve Moeng, Martin C. Robson
Surgical Science (SS) , 2018, DOI: 10.4236/ss.2018.97025
Abstract: Background: Dressing of split-thickness skin graft donor sites can be traumatic for the patient. The most advanced and expensive dressings have been compared to the most basic of dressings, with little or no consensus and an unpersuasive level of evidence. We aimed to determine the efficacy of the locally manufactured non-adherent, hydroconductive Drawtex? dressing and compare it to our current standard-of-care dressing, a thin transparent polyurethane film, in the healing of split-thickness donor sites. Methods: This prospective, within-patient controlled study included 27 adult participants, each with two split-thickness skin donor sites. The 54 donor site wounds were compared with regard to time to re-epithelialisation, perceived pain and healed wound quality. Results: By day 5, complete healing of donor site wounds, defined as >90% of epithelialized surface, was significantly higher in the hydroconductive dressing group compared to the polyurethane film group (22.2% and 3.7%, respectively; p < 0.0001). The hydroconductive dressing-treated donor site wounds were significantly less painful at 24-hours, 48-hours and 7-days post-operatively, and had fewer complications and superior wound healing quality. Conclusion: We have demonstrated that the relatively cheap and readily available dressing made locally in South Africa, Drawtex? is at least as safe, and potentially superior in wound healing, when compared to our current standard-of-care dressing.
Functional outcome in conservatively treated non-displaced scaphoid fractures  [PDF]
Tessa Drijkoningen, Frank J. P. Beeres, Roderick H. van Leerdam, Daan Ootes, Diana C. Grootendorst, Marleen Otoide-Vree, Steven J. Rhemrev
Open Journal of Clinical Diagnostics (OJCD) , 2012, DOI: 10.4236/ojcd.2012.24015
Abstract: Purpose: This study evaluated the functional outcome after conservative treatment of non-displaced scaphoid fractures using an international validated outcome scale (DASH). Methods and materials: Between 2005 and 2010, 60 patients with a non-displaced scaphoid fracture were included. When a patient visited the emergency department and was clinically suspected of a scaphoid fracture radiography was performed. If no fracture was diagnosed with this modality a CT or MRI-scan both in combination with bonescintigraphy was performed. Patients with scaphoid fractures diagnosed with CT/MRI and bonescintigraphy were treated with a six-week scaphoid forearm cast. Within 1 year after cast removal patients filled in the DASH questionnaire. Results: Sixty (80%) patients returned the DASH questionnaire at 12 months after treatment. Thirty-eight (63.3%) were male and the mean age was 35 (range 11 - 83). Forty-four (73.3%) patients had a mid-waist fracture of the scaphoid, 13 (21.7%) had a fracture of the distal pole and three (0.05%) had a proximal fracture. Median DASH score at one year after the trauma was 6 (range 3 - 15) for patients with a distal pole fracture and 5 (range 0 - 21.5) for mid-waist fractures (p = 0.7, table 2). For the three patients with a proximal scaphoid fracture the DASH scores appeared higher and were 83, 82 and 30 respectively. Conclusion: Conservative treatment for six weeks with a below the elbow cast is sufficient for the majority of patients with an occult distal or mid-waist scaphoid fracture and results in a good functional outcome according to the DASH questionnaire.
Improving the use of research evidence in guideline development: 11. Incorporating considerations of cost-effectiveness, affordability and resource implications
Tessa Edejer
Health Research Policy and Systems , 2006, DOI: 10.1186/1478-4505-4-23
Abstract: We reviewed the literature on incorporating considerations of cost-effectiveness, affordability and resource implications in guidelines and recommendations.We searched PubMed and three databases of methodological studies for existing systematic reviews and relevant methodological research. We did not conduct systematic reviews ourselves. Our conclusions are based on the available evidence, consideration of what WHO and other organisations are doing and logical arguments.When is it important to incorporate cost-effectiveness, resource implications and affordability considerations in WHO guidelines (which topics)?? For cost-effectiveness:The need for cost/effectiveness information should be dictated by the specific question, of which several may be addressed in a single guideline. It is proposed that the indications for undertaking a cost-effectiveness analysis (CEA) could be a starting point for determining which recommendation(s) in the guideline would benefit from such analysis.? For resource implications/affordability:The resource implications of each individual recommendation need to be considered when implementation issues are being discussed.How can cost-effectiveness, resource implications and affordability be explicitly taken into account in WHO guidelines?? For cost-effectiveness:° If data are available, the ideal time to consider cost-effectiveness is during the evidence gathering and synthesizing stage. However, because of the inconsistent availability of CEAs and the procedural difficulty associated with adjusting results from different CEAs to make them comparable, it is also possible for cost-effectiveness to be considered during the stage of developing recommendations.° Depending on the quantity and quality and relevance of the data available, such data can be considered in a qualitative way or in a quantitative way, ranging from a listing of the costs to a modelling exercise. At the very least, a qualitative approach like a commentary outlining the ec
A Phenomenological Study of Ginger Compress Therapy for People with Osteoarthritis
Tessa Therkleson
Indo-Pacific Journal of Phenomenology , 2010,
Abstract: This paper claims rigour and sensitivity for a methodology used to explore multiple sources of data and expose the essential characteristics of a phenomenon in the human sciences. A descriptive phenomenological methodology was applied in a study of the experience of ten people with osteoarthritis receiving ginger compress therapy. The application of the phenomenological attitude, with reduction, bracketing and imaginative variation, allowed multiple sources of data – written, pictorial and oral – to be explicated. The applied methodology used is described in this paper, with its six clearly defined steps illustrated by examples from the study. The findings demonstrate that phenomenological reduction enabled an indication of the potential benefits of ginger compress treatment as a therapy for people with osteoarthritis. Indo-Pacific Journal of Phenomenology, May 2010, Volume 10, Edition 1
Profile: Tessa Nettleton
Tessa Nettleton
Partnership : the Canadian Journal of Library and Information Practice and Research , 2010,
Mbizi, Jean-Baptiste Mabalutila. Les tribulations de Tila
Tessa Lofthouse
Voix Plurielles , 2012,
Abstract: Mbizi, Jean-Baptiste Mabalutila. Les tribulations de Tila. Compte rendu
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