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Search Results: 1 - 10 of 462988 matches for " Tersilia García Castellanos "
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Utility of C-Reactive Protein and Procalcitonin for Detecting Bloodstream Infection in Patients with HIV/AIDS  [PDF]
Arianna Castillo Marshall, Tersilia García Castellanos, Isabel Martínez Motas, Daniel Salazar Rodriguez, María Eugenia Toledo Romaní, Jorge Pérez ávila
World Journal of AIDS (WJA) , 2014, DOI: 10.4236/wja.2014.43033
Abstract:

Human immunodeficiency virus (HIV) infected persons, are at high risk for developing a bloodstream infection. In order to evaluate the usefulness of C-reactive protein (CRP) and procalcitonin (PTC) in the detection of bloodstream infection in HIV, a case-control study was conducted from February to December 2012. PCT and CPR levels were measured in 2 groups. PCT concentrations were measured by the VIDAS® Brahms PCT assay, and CRP concentrations were determined by CRP latex. Values were calculated for both biomarkers and discriminative ability of PCT and CRP was analyzed using ROC curves. There were no significant differences between the study group and the control groups with respect to CRP levels. However, they were much higher PCT levels in patients with bacteremia. PCT showed greater discriminating ability compared to CRP, and proved to be a valuable tool for the detection of systemic bacterial infections in HIV infected patients.

Caracterización fenotípica de enterobacterias aisladas en pacientes con el virus de la inmunodeficiencia humana/sida Phenotypic characterization of enterobacteria isolated from patients with human immunodeficiency virus infection/AIDS
Tersilia García Castellanos,Daniel Salazar Rodríguez,Franger Castillo Kindelán,Wilder Rodríguez Soto
Revista Cubana de Medicina Tropical , 2013,
Abstract: Introducción: en pacientes con el virus de la inmunodeficiencia humana/sida se incrementa el riesgo de padecer infecciones por enterobacterias. Objetivo: caracterizar fenotípicamente las enterobacterias causantes de infecciones en estos pacientes. Métodos: se realizó un estudio descriptivo prospectivo, en el Instituto "Pedro Kourí", de marzo de 2010 a marzo de 2011. Se procesaron muestras de esputo, lavado bronquial, secreciones faríngeas, óticas y vaginales, orina, fecales, lesiones de piel, sangre y catéteres, en 65 pacientes (ambulatorios y hospitalizados). La identificación bacteriológica y la susceptibilidad antimicrobiana de los 73 aislamientos, se determinaron mediante sistema VITEK 2 Compact (bioMérieux, Francia). Resultados: se identificaron Escherichia coli (30), Klebsiella spp. (19), Enterobacter spp. (15), Proteus spp. (7) y Serratia spp. (2). Prevalecieron las sepsis en pacientes hospitalizados (87,7 %). Menos de 50 % de las enterobacterias resultaron resistentes a las cefalosporinas, excepto Klebsiella spp. y Enterobacter spp. (68,4 % y 93,3 % de resistencia a cefepima y cefoxitina, respectivamente), y más del 80 % se mostró sensible a la amikacina. Se observó resistencia a piperazilina/tazobactam y ciprofloxacina en 27,3 % y 15 %, respectivamente. Se detectó 34,2 % de cepas productoras de betalactamasas de espectro extendido. Conclusiones: Escherichia coli y Klebsiella spp. causan frecuentemente infecciones en pacientes VIH/sida. El estudio de la sensibilidad antimicrobiana por VITEK 2 Compact, sugiere que las cefalosporinas, aminoglucósidos, quinolonas y piperacilina/tazobactam, pudieran constituir una alternativa terapéutica en estos casos. Introduction: the risk of infections caused by enterobacteria increases in HIV patients. Objective: to phenotypically characterize the enterobacteria responsible for infections in these patients. Methods: a prospective and descriptive study was conducted in "Pedro Kourí" Institute from March 2010 to March 2011. Samples of sputum, bronchial lavage, pharyngeal, ear and vaginal secretions, urine, stool, skin lesions, blood and catheters taken from 65 patients (ambulatory and hospital) were processed. Bacterial identification and antimicrobial susceptibility of 73 isolates were determined by automated system VITEK 2 Compact (bioMérieux, France). Results: Escherichia coli (30), Klebsiella spp. (19), Enterobacter spp. (15), Proteus spp. (7) and Serratia spp. (2) were identified. Sepsis in hospitalized patients (87.7 %) was prevalent. Less than 50 % of Enterobacteriaceae were resistant to cephalosporins, ex
Neumonía bacteriana en pacientes VIH/sida Bacterial pneumonia in HIV/AIDS patients
Tersilia García Castellanos,Denis Verdasquera Corcho,Jorge Pérezávila,Isabel Martínez Mota
Revista Cubana de Investigaciones Biom??dicas , 2010,
Abstract: Introducción: En los pacientes VIH/sida son múltiples los factores de riesgo que se involucran en la aparición de la neumonía bacteriana de diversa etiología, sin que en ocasiones se conozca el germen causal del cuadro respiratorio. Métodos: Se estudiaron 85 pacientes VIH/sida con diagnóstico de neumonía bacteriana según criterios clínicos, radiológicos y de laboratorio en el Instituto de Medicina Tropical "Pedro Kourí", entre noviembre de 2007 y abril de 2008. Resultados: Se identificaron con mayor frecuencia S. pneumoniae (40,5 %), las enterobacterias (28,3 %) y los bacilos no fermentadores (13,5 %). Prevalecieron los individuos menores de 50 a os de edad (91,7 %), fumadores (65,9 %), con un conteo de linfocitos TCD4 menor de 200 cél/mm3 (64,7 %)y que emplearon terapia antirretroviral de alta eficacia (54,7 %). Constituyeron factores de riesgo para presentar una neumonía bacteriana por enterobacterias, la edad 3 50 a os (OR 2,50; IC= 95 % 1,40-15,1) y la desnutrición (OR 2,53; IC= 95 % 1,83-7,91). Conclusiones: Se demostró que los agentes etiológicos identificados en esputos de pacientes VIH/sida cubanos con NB, son similares a los descritos por otros autores a nivel internacional, siendo más probable que los enfermos mayores de 50 a os y desnutridos presenten una NB causada por enterobacterias que por el resto de los microorganismos. Introduction: In HIV/AIDS patients are many the risk factors involved in appearance of the bacterial pneumonia (BP) of different origin without to know the causal germ of respiratory picture. Methods: Authors studied 85 HIV/AIDS patients diagnosed with BP according the clinical, radiological and laboratory criteria in the "Pedro Kourí" Tropical Medicine Institute between November, 2007 and April, 2008. Results: S. pneumoniae (40,5 %), enterobacteria (28,3%) and no-fermented bacilli (13,5 %) were the more frequent identified. There was prevalence of subjects aged under 50 (91,7 %), smokers (65,9 %), with a TDC4 lymphocytes count under 200 cél/mm3 (64,7 %) with a high-performance anti-retroviral therapy (54,7 %). Risk factors of BP due to enterobacteria included age 3 50 years (OR 2,50; 95 % CI 1,40-15,1) and malnutrition (OR 2,53; 95 % CI 1,83-7,91). Conclusions: It was demonstrated that the etiological agents identified in sputum from HIV/AIDS Cuban patients presenting with BP are similar to those described by other authors at international level, being more probable that the ill persons aged over 50 and also malnourished have a BP due to enterobacteria than remainder microorganisms.
Identificación y sensibilidad antimicrobiana de bacterias gramnegativas causantes de neumonía en pacientes VIH/sida Identification and antimicrobial sensitivity of gramnegative bacteria causing pneumonia in HIV/AIDS patients
Tersilia García Castellanos,Isabel Martínez Mota,Daniel Salazar Rodríguez,Miriam Pérez Monrás
Revista Cubana de Investigaciones Biom??dicas , 2012,
Abstract: Las bacterias gramnegativas se consideran como causa frecuente de neumonía en pacientes VIH/sida. La emergente y elevada proporción de microorganismos resistentes obliga a utilizar el antibiograma como un método que definirá la terapéutica de estos pacientes. Objetivos: identificar las bacterias gramnegativas que causan neumonía en pacientes VIH/sida y determinar la sensibilidad antimicrobiana de los microorganismos aislados. Métodos: se realizó un estudio descriptivo prospectivo en el Instituto "Pedro Kourí" de 85 pacientes con VIH/sida y diagnóstico presuntivo de neumonía bacteriana por criterios clínicos y radiológicos. Se recogieron muestras de esputo y sangre para cultivo. Las bacterias aisladas y la sensibilidad antimicrobiana se determinaron por el sistema semiautomatizado miniApi (bioMérieux). Resultados: se aislaron 74 bacterias potencialmente patógenas de las que 32 (43,2 %) se clasificaron como gramnegativas. Predominaron Klebsiella pneumoniae (11 cepas: 34,3 %), Pseudomonas spp. (8 cepas: 25 %) y Escherichia coli (4 cepas: 12,5 %). Escherichia coli mostró el mayor porcentaje de resistencia y el 75 % de las cepas fue sensible frente a la amikacina. No se encontró resistencia al meropenem y más del 50 % de las enterobacterias identificadas con excepción de E.coli fueron sensibles a las cefalosporinas de tercera generación, ciprofloxacina, amikacina y cotrimoxazol. Pseudomonas spp. presentó resistencia al cotrimoxazol (87 %) y ticarcilina (75 %). Conclusiones: las bacterias gramnegativas causan en un porcentaje no despreciable neumonía en pacientes con VIH/sida. Aunque persisten cepas resistentes frente a diversos antimicrobianos, las cefalosporinas, quinolonas y los carbapenémicos muestran una adecuada actividad frente a estas bacterias. Gramnegative bacteria are considered to be a common cause of pneumonia in HIV/AIDS patients. The emergence of a large number of resistant microorganisms has made it necessary to use antibiograms to decide what treatment will be applied to these patients. Objectives: identify gramnegative bacteria causing pneumonia in HIV/AIDS patients and determine the antimicrobial sensitivity of the microorganisms isolated. Methods: a prospective descriptive study of 85 patients with HIV/AIDS and presumed diagnosis of bacterial pneumonia was carried out at "Pedro Kouri" Institute applying clinical and radiological criteria. Sputum and blood samples were collected to be cultured. The bacteria isolated and their antimicrobial sensitivity were determined using the mini-Api (bioMérieux) semiautomated system. Results: seventy-four
Neumonía bacteriana en pacientes VIH/sida
García Castellanos,Tersilia; Verdasquera Corcho,Denis; Pérezávila,Jorge; Martínez Mota,Isabel; Salazar Rodríguez,Daniel; Pérez Monrás,Miriam;
Revista Cubana de Investigaciones Biom??dicas , 2010,
Abstract: introduction: in hiv/aids patients are many the risk factors involved in appearance of the bacterial pneumonia (bp) of different origin without to know the causal germ of respiratory picture. methods: authors studied 85 hiv/aids patients diagnosed with bp according the clinical, radiological and laboratory criteria in the "pedro kourí" tropical medicine institute between november, 2007 and april, 2008. results: s. pneumoniae (40,5 %), enterobacteria (28,3%) and no-fermented bacilli (13,5 %) were the more frequent identified. there was prevalence of subjects aged under 50 (91,7 %), smokers (65,9 %), with a tdc4 lymphocytes count under 200 cél/mm3 (64,7 %) with a high-performance anti-retroviral therapy (54,7 %). risk factors of bp due to enterobacteria included age 3 50 years (or 2,50; 95 % ci 1,40-15,1) and malnutrition (or 2,53; 95 % ci 1,83-7,91). conclusions: it was demonstrated that the etiological agents identified in sputum from hiv/aids cuban patients presenting with bp are similar to those described by other authors at international level, being more probable that the ill persons aged over 50 and also malnourished have a bp due to enterobacteria than remainder microorganisms.
La combinación de funciones de la enfermera comunitaria dentro del equipo básico de salud The combination of community nursing functions in the basic health care team
Tania García Castellanos
Revista Cubana de Enfermer?-a , 2012,
Abstract:
Valoración contingente y fútbol: la cuantificación de la disposición a pagar
Pablo Castellanos García
Revista Galega de Economía , 2008,
Abstract: Este artículo analiza si el formato de la pregunta de disposición a pagar tiene algún efecto en la estimación, a través del método de valoración contingente, del valor de los bienes públicos generados por un equipo de fútbol profesional. Para responder a esta cuestión se utilizaron datos de una encuesta con formato mixto dicotómico-abierto, realizada mediante entrevistas personales a 800 individuos. A partir de dichos datos, la evidencia empírica obtenida a través de modelos Tobit y logit revela significativas diferencias en los resultados, dependiendo de cómo se formule la pregunta de disposición a pagar. Por lo tanto, los valores obtenidos en estudios anteriores deberían ser considerados con cautela.
EVALUACIóN DEL EFECTO SANITIZANTE DE UN EXTRACTO BIODEGRADABLE OBTENIDO DE LA ESPECIE Solanum marginatum, DE USO ETNOBOTáNICO EN BOYACá
GARCíA COLMENARES,MAURICIO; CASTELLANOS CORREDOR,MARíA CRISTINA;
Luna Azul , 2011,
Abstract: plants of the genus solanum, within which the "lulo perro" (solanum marginatum) is found and is considered as a weed species, contain saponins which have fat emulsifying properties similar to soap. this feature was used to evaluate the sanitizing power of the alcoholic extract of the fruit as a biodegradable cleaner which is very useful for industrial purposes. the sanitizing potential of the cleaner preparation was assessed using the procedure described by carrascal, páez y burbano (1998), and it was found to have optimum antimicrobial effectiveness conditions: a 10% concentration and a 6 minute contact time over gram negative bacilli microorganisms which represent a maximum inhibition of 99 58%. when comparing the effectiveness of the product against two well-known commercial sanitizers. (mat-98? and germigel?), a similar response was found. using crude hydrolysis of saponin, present sapogenins were released, the crystals obtained were analyzed using infrared spectroscopy, and melting point was determined. these results coincided with the hecogenin.
EVALUATION OF THE SANITIZER EFFECT OF A BIODEGRADABLE EXTRACT OF ETHNOBOTANICAL USE IN BOYACá, OBTAINED FROM THE Solanum marginatum SPECIES
MAURICIO GARCíA COLMENARES,MARíA CRISTINA CASTELLANOS CORREDOR
Luna Azul , 2011,
Abstract: Plants of the genus Solanum, within which the "Lulo perro” (Solanum marginatum) is found and is considered as a weed species, contain saponins which have fat emulsifying properties similar to soap. This feature was used to evaluate the sanitizing power of the alcoholic extract of the fruit as a biodegradable cleaner which is very useful for industrial purposes. The sanitizing potential of the cleaner preparation was assessed using the procedure described by Carrascal, Páez y Burbano (1998), and it was found to have optimum antimicrobial effectiveness conditions: a 10% concentration and a 6 minute contact time over gram negative bacilli microorganisms which represent a maximum inhibition of 99 58%. When comparing the effectiveness of the product against two well-known commercial sanitizers. (Mat-98 and Germigel ), a similar response was found. Using crude hydrolysis of saponin, present sapogenins were released, the crystals obtained were analyzed using infrared spectroscopy, and melting point was determined. These results coincided with the Hecogenin.
La difusión de las investigaciones y el formato IMRYD: Una pesquisa a propósito de la lectura crítica de los artículos científicos
García del Junco,Julio; Castellanos Verdugo,Mario;
ACIMED , 2007,
Abstract: the importance of the format imryd -introduction, methods, results and discussion- for the organization of the scientific article among the investigators and professors of marketing and businesses organization is studied. 143 professors of the referred areas were interviewed in order to know which are the aspects considered by them as the most important in this structure. once the collected data were computerized, rasch's model was applied to determine the aspects chosen as the most significant by the group of experts consulted. these specialists indicated a total of 20 aspects as the most relevant to evaluate the quality of a scientific article. finally, from the aspects mentioned by the experts consulted, a guide for the critical reading of the scientific articles in the areas of marketing and business organization was made.
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