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Search Results: 1 - 10 of 1158 matches for " Tatsuya Ohno "
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Development of Nursing Protocol for Preventing Discontinuation of Treatments by Methods Other than Physical Restraint during Acute Exacerbation of Chronic Heart Failure in Patients with Impaired Cognitive Function  [PDF]
Haruka Otsu, Shiori Fujimoto, Nozomi Murakami, Tatsuki Ohhara, Yoko Takeya, Tatsuya Ohno, Chieko Suzuki, Sanae Takahashi
Health (Health) , 2018, DOI: 10.4236/health.2018.106060
Abstract: The purpose of this study is to prepare a nursing protocol for preventing discontinuation of treatments using a method other than physical restraint during acute exacerbation of chronic heart failure in patients with impaired cognitive function. For the first stage of the study, we prepared a draft of the nursing protocol based on a basic survey. For the second stage, semi-structured interviews were conducted with 5 nurses specialized in chronic heart failure and 10 nurses in dementia case to ensure content validity of the draft protocol. For the third stage, we examined the possibility of clinical application of the revised version of the protocol draft prepared in the second stage of the study. For assessment items, significant points of nursing care, and specific nursing care practice in this revised version, 154 subjects (93.9%) considered effective for patients, in terms of prevention of treatment discontinuation using a method other than physical restraint. All items and contents were considered useful by more than 60% of the nurses. Considering that the nurses working in the clinical setting reported 93.9% of usefulness, we concluded that this nursing protocol remained valid at a certain level. We also received a comment from the certified nurses that we should include the basic contents for newly graduated nurses. We consider that this nursing protocol will be also useful for newly graduated nurses to acquire knowledge. It helped to standardize nursing care in order to predict potential risks for patients with impaired cognitive function.
Carbon-Ion Beams Efficiently Induce Cell Killing in X-Ray Resistant Human Squamous Tongue Cancer Cells  [PDF]
Akihisa Takahashi, Hongyu Ma, Akiko Nakagawa, Yukari Yoshida, Tatsuaki Kanai, Tatsuya Ohno, Yoshikazu Kuwahara, Manabu Fukumoto, Takashi Nakano
International Journal of Medical Physics,Clinical Engineering and Radiation Oncology (IJMPCERO) , 2014, DOI: 10.4236/ijmpcero.2014.33019

In order to see whether carbon ion (C-ion) beams have a biological advantage over X-rays, studies were designed to examine the effects of C-ion beams on radiosensitivity in X-ray resistant cells. Clinically relevant X-ray resistant SAS-R cells derived from human tongue cancer SAS cells were used. The cells were exposed to X-rays or Spread-Out Bragg peak (SOBP) beam C-ions. Cell survival was measured using a modified high-density survival assay. Cell survival signaling and cell death signaling were analyzed using flow cytometry. The cells were labeled with putative cancer stem cell markers such as CD44 and CD326. SAS-R cells were 1.6 times more radioresistant than SAS cells after exposure to X-rays. Cell survival was similar in each cell line after exposure to C-ion beams. SAS-R cells displayed enhanced cell survival signaling when compared to SAS cells under normal conditions. On the other hand, the phosphorylation of AKT-related proteins decreased and polycaspase activities were enhanced when cells were irradiated with C-ion beams in both cell lines. More CD44 and CD326 positive cells were seen in SAS-R cells than in SAS cells. Moreover, the marker positive cell numbers significantly decreased after exposure to C-ion beams when compared to X-rays at iso-survival doses in SAS-R cells. C-ion beams efficiently induced cell killing in X-ray resistant cells which displayed activated cell survival signaling and contained more numerous cancer stem-like cells. 

Non-commutative hypergroup of order five
Yasumichi Matsuzawa,Hiromichi Ohno,Akito Suzuki,Tatsuya Tsurii,Satoe Yamanaka
Mathematics , 2015,
Abstract: We prove that all hypergroups of order four are commutative and that there exists a non-comutative hypergroup of order five. These facts imply that the minimum order of non-commutative hypergroups is five even though the minimum order of non-commutative groups is six.
Use of FDG-PET in Radiation Treatment Planning for Thoracic Cancers
Katsuyuki Shirai,Akiko Nakagawa,Takanori Abe,Masahiro Kawahara,Jun-ichi Saitoh,Tatsuya Ohno,Takashi Nakano
International Journal of Molecular Imaging , 2012, DOI: 10.1155/2012/609545
Abstract: Radiotherapy plays an important role in the treatment for thoracic cancers. Accurate diagnosis is essential to correctly perform curative radiotherapy. Tumor delineation is also important to prevent geographic misses in radiotherapy planning. Currently, planning is based on computed tomography (CT) imaging when radiation oncologists manually contour the tumor, and this practice often induces interobserver variability. F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) has been reported to enable accurate staging and detect tumor extension in several thoracic cancers, such as lung cancer and esophageal cancer. FDG-PET imaging has many potential advantages in radiotherapy planning for these cancers, because it can add biological information to conventional anatomical images and decrease the inter-observer variability. FDG-PET improves radiotherapy volume and enables dose escalation without causing severe side effects, especially in lung cancer patients. The main advantage of FDG-PET for esophageal cancer patients is the detection of unrecognized lymph node or distal metastases. However, automatic delineation by FDG-PET is still controversial in these tumors, despite the initial expectations. We will review the role of FDG-PET in radiotherapy for thoracic cancers, including lung cancer and esophageal cancer. 1. Introduction Radiotherapy plays an important role in the treatment of thoracic cancers, such as non-small-cell lung cancer (NSCLC), small-cell lung cancer (SCLC), and esophageal cancer [1, 2]. Recent advances in accurate diagnosis improve the practice of curative radiotherapy, because patients with unsuspected metastases may avoid unnecessary local therapies and receive necessary systemic treatment. Accurate delineation of tumor volume is also important to prevent geographic misses in treatment planning. Indeed, an underestimation of tumor extension will result in tumor recurrence. In contrast, overestimation of the extension may increase unnecessary side effects. Therefore, delineation of tumor volumes is a crucial factor in curative radiotherapy. Currently, treatment planning is based on computed tomography (CT) imaging to contour the tumor. Tumor delineation is manually performed by each radiation oncologist in clinical practice, which leads to interobserver variability in tumor delineation. Accurate delineation of tumor volume requires the identification of anatomic borders of tumors based on accurate diagnosis. F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) and PET/CT have been reported to enable accurate staging and
An Integrating Algorithm and Theoretical Analysis for Fully Rheonomous Affine Constraints: Completely Integrable Case  [PDF]
Tatsuya Kai
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.412235

This paper develops an integrating algorithm for fully rheonomous affine constraints and gives theoretical analysis of the algorithm for the completely integrable case. First, some preliminaries on the fully rheonomous affine constraints are shown. Next, an integrating algorithm that calculates independent first integrals is derived. In addition, the existence of an inverse function utilized in the algorithm is investigated. Then, an example is shown in order to evaluate the effectiveness of the proposed method. By using the proposed integrating algorithm, we can easily calculate independent first integrals for given constraints, and hence it can be utilized for various research fields.

On Integrability of Fully Rheonomous Affine Constraints  [PDF]
Tatsuya Kai
International Journal of Modern Nonlinear Theory and Application (IJMNTA) , 2013, DOI: 10.4236/ijmnta.2013.22016

This paper presents a complete integrability condition for fully rheonomous affine constraints in terms of the rheonomous bracket. We first define fully rheonomous affine constraints and develop geometric representation for them. Next, the rheonomous bracket is explained and some properties of it are derived. We then investigate a necessary and sufficient condition on complete integrability for the fully rheonomous affine constraints based on the rheonomous bracket as an extension of Frobenius’ theorem. The effectiveness and the availability of the new results are also evaluated via an example.

Partial Integrability Conditions and an Integrating Algorithm for Fully Rheonomous Affine Constraints  [PDF]
Tatsuya Kai
Circuits and Systems (CS) , 2014, DOI: 10.4236/cs.2014.56015

In this paper, integrability conditions and an integrating algorithm of fully rheonomous affine constraints (FRACs) for the partially integrable case are studied. First, some preliminaries on the FRACs are illustrated. Next, necessary and sufficient conditions on the partially integrable case for the FRACs are derived. Then, an integrating algorithm to calculate independent first integrals of the FRACs for the partially integrable case is derived. Moreover, the existence of an inverse function utilized in the algorithm is proven. After that, an example is presented for evaluation of the effectiveness of the proposed method. As a result, it turns out that the proposed integrating algorithm can easily calculate independent first integrals for given partially integrable FRACs, and thus this new algorithm is expected to be applied to various research fields.

Circular Obstacle Avoidance Control of the Compass-Type Biped Robot Based on a Blending Method of Discrete Mechanics and Nonlinear Optimization  [PDF]
Tatsuya Kai
International Journal of Modern Nonlinear Theory and Application (IJMNTA) , 2015, DOI: 10.4236/ijmnta.2015.43013
Abstract: This paper considers an obstacle avoidance control problem for the compass-type biped robot, especially circular obstacles are dealt with. First, a sufficient condition such that the swing leg does not collide the circular obstacle is derived. Next, an optimal control problem for the discrete compass-type robot is formulated and a solving method of the problem by the sequential quadratic programming is presented in order to calculate a discrete control input. Then, a transformation method that converts a discrete control input into a continuous zero-order hold input via discrete Lagrange-d’ Alembert principle is explained. From the results of numerical simulations, it turns out that obstacle avoidance control for the continuous compass-type robot can be achieved by the proposed method.
A New Efficient Obstacle Avoidance Control Method for Cars Based on Big Data and Just-in-Time Modeling  [PDF]
Tatsuya Kai
Journal of Computer and Communications (JCC) , 2018, DOI: 10.4236/jcc.2018.611002
Abstract: This paper provides a new obstacle avoidance control method for cars based on big data and just-in-time modeling. Just-in-time modeling is a new kind of data-driven control technique in the age of big data and is used in various real systems. The main property of the proposed method is that a gain and a control time which are parameters in the control input to avoid an encountered obstacle are computed from a database which includes a lot of driving data in various situations. Especially, the important advantage of the method is small computation time, and hence it realizes real-time obstacle avoidance control for cars. From some numerical simulations, it is showed that the new control method can make the car avoid various obstacles efficiently in comparison with the previous method.
Molecular Motion on Semiconductor Surface via Tip-enhanced Multiple Excitation
Tatsuya Momose,Ken-ichi Shudo,Hannes Raebiger,Shin-ya Ohno,Takeshi Kitajima,Masanobu Uchiyama,Takanori Suzuki,Masatoshi Tanaka
Physics , 2012,
Abstract: In a low-temperature study with a scanning tunneling microscope (STM), the irreducible lateral motion of a CO molecule adsorbed on a Si(001) surface showed a hyperlinear dependence on the tunneling current. This dependence implies that the adsorbate displacement is caused by multiple excitations of adsorbate vibration modes, a situation thus far observed only at metal surfaces. The local vibronic temperature at the atomic scale on the surface heated by ohmic inelastic scattering of tunneling electrons indicates that there is an activation barrier of 0.11 eV for the irreversible motion of CO, in agreement with the adiabatic potential obtained from first-principles calculation. The highly efficient local heating is caused by a mid-gap state at the surface induced by the electric field of the STM tip.
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