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Search Results: 1 - 10 of 3940 matches for " Tania Robyn Chase "
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CuradermBEC5 for Skin Cancers, Is It? An Overview  [PDF]
Tania Robyn Chase
Journal of Cancer Therapy (JCT) , 2011, DOI: 10.4236/jct.2011.25099
Abstract: Skin cancer incidence is increasing at alarming rates and is considered by some as an epidemic. Its incidence is higher than all other cancers combined. The developments of new treatments have not parallelled the increased incidences of this disease. A variety of treatments are available with differing outcomes. More recently a novel topical treatment, consisting of the antineoplastic compounds solasodine rhamnosyl glycosides, solamargine and solasonine, which are derived from plant material, has been described that claims to have many advantages over the currently used skin cancer therapies. This review investigates such claims.
Intravascular infusion of autologous delipidated plasma induces antiatherogenic lipoproteins and causes regression of atherosclerosis
—Studies in non-primates, monkeys and humans
 [PDF]

Bill E. Cham, Tania R. Chase
Health (Health) , 2013, DOI: 10.4236/health.2013.57A1003
Abstract:

Atherosclerosis is the primary pathophysiological cause of heart disease and cerebrovascular disease. It is responsible for more than 20% of deaths worldwide each year. Treatments for atherosclerosis may include lifestyle changes, drugs, and medical procedures or surgery. There is a need for a rapid and effective treatment for this disease. In 1976, it was hypothesized that a multifunctional plasma delipidation process when applied to hyperlipidemic patients would lead to rapid regression of atherosclerosis. The procedure has now been applied to a variety of non-primates, primates and humans. In all models studied, large quantities of antiatherogenic lipoprotein particles were generated that led to the mechanisms of reverse cholesterol transport. Trends to regression and actual regression of atherosclerosis have now been reported using a specific plasma delipidation process consisting of lipid extraction from plasma with mixtures of butanol and ethers.

Solasodine Glycosides from the Eggplant in a Topical Cream PsorendBEC Are Effective against Psoriasis  [PDF]
Tania R. Chase, Kai E. Cham, Bill E. Cham
International Journal of Clinical Medicine (IJCM) , 2019, DOI: 10.4236/ijcm.2019.103017
Abstract: Background: Psoriasis is a chronic disease that can have significant effects on quality of life. Aim: To test whether the antineoplastic, antipathogenic plant derived secondary metabolites, solasodine glycosides, can treat psoriasis. Case Presentation: We report a case of a 54-year-old French-Vietnamese male who presented with diagnosed erythematous scaly annular recalcitrant psoriasis scattered throughout his body. Method: After failing conventional treatment regimens for over 10 years the patient received a trial with a topical cream formulation PsorendBEC, containing solasodine glycosides, for his psoriasis. Result: Topical applications of PsorendBEC twice daily resulted in complete resolution of cutaneous lesions after 4 weeks of treatment with no recurrence post 1 year after therapy. Conclusion: Topical PsorendBEC therapy rapidly removes recalcitrant psoriasis with no apparent side effects.
Cardiomyopathy Following Latrodectus Envenomation
Levine, Michael,Canning, Joshua,Chase, Robyn,Ruha, Anne-Michelle
Western Journal of Emergency Medicine : Integrating Emergency Care with Population Health , 2010,
Abstract: Latrodectus envenomations are common throughout the United States and the world. While many envenomations can result in catecholamine release with resultant hypertension and tachycardia, myocarditis is very rare. We describe a case of a 22- year-old male who sustained a Latrodectus envenomation complicated by cardiomyopathy. [West J Emerg Med. 2010; 11(5):521-523.]
D1 Dopamine Receptor Signaling Is Modulated by the R7 RGS Protein EAT-16 and the R7 Binding Protein RSBP-1 in Caenoerhabditis elegans Motor Neurons
Khursheed A. Wani, Mary Catanese, Robyn Normantowicz, Muriel Herd, Kathryn N. Maher, Daniel L. Chase
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0037831
Abstract: Dopamine signaling modulates voluntary movement and reward-driven behaviors by acting through G protein-coupled receptors in striatal neurons, and defects in dopamine signaling underlie Parkinson's disease and drug addiction. Despite the importance of understanding how dopamine modifies the activity of striatal neurons to control basal ganglia output, the molecular mechanisms that control dopamine signaling remain largely unclear. Dopamine signaling also controls locomotion behavior in Caenorhabditis elegans. To better understand how dopamine acts in the brain we performed a large-scale dsRNA interference screen in C. elegans for genes required for endogenous dopamine signaling and identified six genes (eat-16, rsbp-1, unc-43, flp-1, grk-1, and cat-1) required for dopamine-mediated behavior. We then used a combination of mutant analysis and cell-specific transgenic rescue experiments to investigate the functional interaction between the proteins encoded by two of these genes, eat-16 and rsbp-1, within single cell types and to examine their role in the modulation of dopamine receptor signaling. We found that EAT-16 and RSBP-1 act together to modulate dopamine signaling and that while they are coexpressed with both D1-like and D2-like dopamine receptors, they do not modulate D2 receptor signaling. Instead, EAT-16 and RSBP-1 act together to selectively inhibit D1 dopamine receptor signaling in cholinergic motor neurons to modulate locomotion behavior.
How Much Lox Is a Grizzly Bear Worth?
Jonathan Chase
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.1001304
Abstract:
Historical and Contemporary Factors Govern Global Biodiversity Patterns
Jonathan Chase
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.1001294
Abstract:
The Country and the City in the Cuban Revolution
Chase,Michelle;
Colombia Internacional , 2011,
Abstract: this article examines the interplay between city and country in the earliest years of the cuban revolution of 1959. it argues that the mass movement of cubans, especially youths, between urban and rural areas was a major factor in contributing to the radical conscious-ness of the 1960s. at the same time, these early initiatives also contributed to the growing disaffection with the cuban revolution. the article, thus, lends insight into the excitement and polarization of cuba's "revolutionary moment."
Psychosocial resilience among resettled Bhutanese refugees in the US
Liana Chase
Forced Migration Review , 2012,
Abstract: Addressing high rates of suicide among resettled Bhutanese refugeescalls for culturally appropriate, community-based approaches tomental health care.
The Country and the City in the Cuban Revolution
Michelle Chase
Colombia Internacional , 2011,
Abstract: This article examines the interplay between city and country in the earliest years of the Cuban Revolution of 1959. It argues that the mass movement of Cubans, especially youths, between urban and rural areas was a major factor in contributing to the radical conscious-ness of the 1960s. At the same time, these early initiatives also contributed to the growing disaffection with the Cuban revolution. The article, thus, lends insight into the excitement and polarization of Cuba's "revolutionary moment."
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