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Search Results: 1 - 10 of 404501 matches for " Tanaka Rosimeire M. "
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Prevalência de depress?o em mulheres com diabetes mellitus tipo 2 na pós-menopausa
Martins, Grasiele L.;Tanaka, Rosimeire M.;Campos, Nelson B.;Dalbosco, Ivaldir S.;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2002, DOI: 10.1590/S0004-27302002000600012
Abstract: the prevalence of depression and its correlations with metabolic control were studied in 80 diabetic postmenopausal women and 45 nondiabetic women, and the beck depression inventory (bdi) was used to assess depression. the prevalence of depression was significantly higher in the group of diabetic postmenopausal women as compared with nondiabetic women (p<0.001; rr= 2.4). nondiabetic patients were older and presented a mean bdi score greater than diabetic patients. furthermore, significantly elevated values of glycemia and hba were observed in diabetic women with depression, demonstrating that they have worse metabolic control than nondepressive women. among depressive diabetic women, the depression was also positively correlated with age but not with the duration of the disease.
Prevalência de depress o em mulheres com diabetes mellitus tipo 2 na pós-menopausa
Martins Grasiele L.,Tanaka Rosimeire M.,Campos Nelson B.,Dalbosco Ivaldir S.
Arquivos Brasileiros de Endocrinologia & Metabologia , 2002,
Abstract: A prevalência de depress o e suas correla es com o controle metabólico foram estudadas em 80 mulheres pós-menopausadas diabéticas e em 45 mulheres n o diabéticas, tendo sido utilizado o questionário de depress o de Beck (QDB) para o diagnóstico de depress o. A prevalência de depress o foi significativamente maior no grupo de diabéticas na pós-menopausa em compara o às n o diabéticas (p<0,001; RR= 2,4). As pacientes n o diabéticas apresentaram média de idade e de pontos do QDB superiores às diabéticas. Além disso, foram observados entre as diabéticas com depress o valores significativamente elevados de glicemia e hemoglobina glicosilada, demonstrando que as diabéticas depressivas apresentaram pior controle metabólico do que as n o depressivas. Entre as diabéticas depressivas, a depress o também se correlacionou positivamente com a idade, mas n o com o tempo de diagnóstico da doen a.
Pneumonia por leptospirose
HüTTNER, MAURA DUMONT;PEREIRA, HUGO CATAUD PACHECO;TANAKA, ROSIMEIRE MITSUKO;
Jornal de Pneumologia , 2002, DOI: 10.1590/S0102-35862002000400007
Abstract: leptospirosis is an infectious disease characterized by multisystemic involvement. the lung involvement is common, usually mild and frequently neglected. when respiratory manifestations are prominent in a patient with leptospirosis, there is the potential for diagnostic confusion. the authors report a severe case of leptospiral pneumonia, with the objective of highlighting this etiological possibility of community pneumonia, especially when there is suspicion of epidemic features.
Pneumonia por leptospirose
HüTTNER MAURA DUMONT,PEREIRA HUGO CATAUD PACHECO,TANAKA ROSIMEIRE MITSUKO
Jornal de Pneumologia , 2002,
Abstract: A leptospirose é uma doen a infecciosa caracterizada pelo envolvimento de múltiplos sistemas. O acometimento pulmonar é comum, geralmente leve e freqüentemente negligenciado. Quando os sintomas respiratórios s o a principal manifesta o da doen a, existe grande possibilidade de confus o diagnóstica. Os autores apresentam um caso de pneumonia grave por leptospirose, com o objetivo de chamar a aten o para esta possibilidade etiológica no diagnóstico diferencial das pneumonias comunitárias, especialmente quando há um perfil epidemiológico suspeito.
Controle genético das células-tronco humanas cultivadas
Pay?o, Spencer L. M.;Segato, Rosimeire;Santos, Ricardo R.;
Revista Brasileira de Hematologia e Hemoterapia , 2009, DOI: 10.1590/S1516-84842009005000021
Abstract: stem cells have a high capacity of self-regeneration, as well as a potential to differentiate into several cell types. these cells can be classified as embryonic or adult. in spite of having inherent properties of stem cells, mesenchymal cells show a certain degree of difficulty to establish cultures. this might induce a loss of the expression of the telomerase enzyme which is considered to be a biological clock or an indicator of the senescence of the cells. the most current and intriguing question for researchers is whether the presumed division potential of cultivated stem cells, over a period of time could result in an accumulation of genetic alterations and consequently, in a neoplastic process. for this reason, cytogenetic techniques are very important to guarantee the control and safety of cultivated stem cells to be used in human therapy. structural chromosomal alterations, such as for example, deletions, translocations and inversions represent an important mechanism by which cells might gradually transform in a neoplastic process. thus, these chromosomal alterations could result in an abnormal expression of the genes and lead to cancer.
SUSY and Flat Direction in de Sitter Space
M. Tanaka
Physics , 1997,
Abstract: We have found that supersymmetry (SUSY) in curved space is broken softly. It is also found that Pauli-Villars regularization preserves the remaining symmetry, softly broken SUSY. Using it we computed the one-loop effective potential along a (classical) flat direction in a Wess-Zumino model in de Sitter space. The analysis is relevant to the Affleck-Dine mechanism for baryogenesis. The effective potential is unbounded from below: $V_{eff}(\phi)\to -3g^2H^2\phi ^2 ln \phi ^2 /16\pi ^2$, where $\phi$ is the scalar field along the flat direction, g is a typical coupling constant, and H is the Hubble parameter. This is identical with the effective potential which is obtained by using proper-time cutoff regularization. Since proper-time cutoff regularization is exact even at the large curvature region, the effective potential possesses softly broken SUSY and reliability in the large curvature region.
Evidence for positive selection on Mycobacterium tuberculosis within patients
Mark M Tanaka
BMC Evolutionary Biology , 2004, DOI: 10.1186/1471-2148-4-31
Abstract: This article presents three lines of evidence supporting the action of positive selection on M. tuberculosis within patients. The arguments are based on a comparison between empirical findings from molecular epidemiology, and population genetic models of evolution. Under the hypothesis of neutrality of genotypes, 1) the mutation rate of the marker IS6110 is unusually high, 2) the time it takes for substitutions to occur within patients is too short, and 3) the amount of polymorphism within patients is too low.Empirical observations are explained by the action of positive selection during infection, or alternatively by very low effective population sizes. I discuss the possible roles of antibiotic treatment, the host immune system and extrapulmonary dissemination in creating opportunities for positive selection.How actively do populations of Mycobacterium tuberculosis cells undergo adaptive evolution on the spatial and temporal scales of individual infections? On the one hand, the long generation time and limited sequence diversity of this organism might suggest a slow pace of adaptive evolution. On the other hand, the rapidity and ease with which antibiotic resistance is generated during infection suggests otherwise. The physiology and immunology of tuberculosis pathogenesis have been well studied. The infectious agent M. tuberculosis is known to invade and replicate within alveolar macrophages. There is a spectrum of responses by the immune system, corresponding to the relative involvement of Thl and Th2 immune cells, which respectively stimulate the cytotoxic response (more effective against infected cells), and the humoral/antibody response (more effective against extracellular pathogens) [1,2]. Some progress has been made in describing the population dynamics of mycobacterial infection quantitatively [3-5]. At the wider spatial and temporal scales of populations, the molecular epidemiology and the evolution of M. tuberculosis have been carefully studied. Genotyp
Evaluation of positioning and density profiling accuracy of muon radiography by utilizing a 15-ton steel block
H. K. M. Tanaka
Geoscientific Instrumentation, Methods and Data Systems (GI) & Discussions (GID) , 2013, DOI: 10.5194/gi-2-79-2013
Abstract: A model experiment was performed in order to evaluate the spatial resolution and the accuracy of determining the density by utilizing a steel block. The steel block (7.8 g cm 3) is 5 m thick along the muon trajectories and weighs about 15 t. By comparing the experimental result with simulations, the density and the width of the steel block were measured as 7.3 ± 1.0 g cm 3 and 37 ± 15 cm, respectively.
Development of stroboscopic muography
H. K. M. Tanaka
Geoscientific Instrumentation, Methods and Data Systems (GI) & Discussions (GID) , 2013, DOI: 10.5194/gi-2-41-2013
Abstract: Conventional muon radiography has concentrated on non-destructive studies of stationary objects with relatively long exposure times required to achieve sufficient muon statistics. A muon detection system with real time readings and a high spatial resolution detector, enables the investigation of dynamic processes in a stroboscopic mode, where image frames are synchronized with the phases of the dynamic target. Although the natural cosmic ray muon flux is quite low for imaging a rapid process, repetitive processes can still be studied with high time resolution by integrating a large number of frames synchronized to the process. In this paper we demonstrate the stroboscopic imaging capabilities of cosmic ray muon radiography with scintillation counters and the muon readout module. The dynamics of a chemical and melting process in an electric furnace with a size of 30 m water equivalent in diameter was investigated as an example, and stroboscopic images were obtained for hourly changes, with acquisition frames of 400 h each. The results of these experiments demonstrate the future potential for muon radiography of repetitional process, such as magma flow in a conduit.
Development of stroboscopic muography
H. K. M. Tanaka
Geoscientific Instrumentation, Methods and Data Systems Discussions , 2012, DOI: 10.5194/gid-2-671-2012
Abstract: Conventional muon radiography has concentrated on non-destructive studies of stationary objects with relatively long exposure times required to achieve sufficient muon statistics. A muon detection system with real time readings and a high spatial resolution detector, enables the investigation of dynamic processes in a stroboscopic mode, where image frames are synchronized with the phases of the dynamic target. Although the natural cosmic-ray muon flux is quite low for imaging a rapid process, repetitive processes can still be studied with high time resolution by integrating a large number of frames synchronized to the process. In this paper we demonstrate the stroboscopic imaging capabilities of cosmic-ray muon radiography with scintillation counters and the muon readout module. The dynamics of a chemical and melting process in an electric furnace with a size of 30 m water equivalent in diameter was investigated as an example, and stroboscopic images were obtained for hourly changes, with acquisition frames of 400 h each. The results of these experiments demonstrate the future potential for muon radiography of repetional process, such as magma flow in a conduit.
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