oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 45 )

2018 ( 297 )

2017 ( 259 )

2016 ( 310 )

Custom range...

Search Results: 1 - 10 of 96149 matches for " Tan?i?-Gaji? Milina "
All listed articles are free for downloading (OA Articles)
Page 1 /96149
Display every page Item
Adrenal incidentaloma in neurofibromatosis type 1
Tani?-GajiMilina,Vujovi? Svetlana,Tati? Svetislav,Stojanovi? Milo?
Srpski Arhiv za Celokupno Lekarstvo , 2008, DOI: 10.2298/sarh0806295t
Abstract: INTRODUCTION Neurofibromatosis type 1 is one of the most common genetically transmitted diseases with a high index of spontaneous mutations and extremely varied and unpredictable clinical manifestations. It is diagnosed by the existence of certain clinical criteria. The presence of numerous localised cutaneous neurofibromas or a plexiform neurofibroma is virtually pathognomonic of neurofibromatosis type 1. The incidence of pheochromocytoma in neurofibromatosis type 1 is 0.1-5.7%. CASE OUTLINE A 56-year old female patient was admitted for further evaluation of incidental adrenal tumour previously diagnosed on computerized tomography (CT). She had previously unrecognized neurofibromatosis type 1 and a clinical picture which could remind of pheochromocytoma. None of the catecholamine samples in 24 hr urine indicated functionally active pheochromocytoma. Chromogranin A was moderately increased. Decision for operation was made after performing the image techniques. Adrenal incidentaloma had features of pheochromocytoma on abdominal magnetic resonance imaging (MRI), with positive 131I-MIBG (iodine 131-labelled metaiodobenzylguanidine scintigraphy). After being treated with phenoxybenzamine and propranolol, she was operated on. The pathohistological finding showed the case of left adrenal pheochromocytoma. CONCLUSION Detailed diagnostic procedure for pheochromocytoma should be performed with patients having neurofibromatosis type 1 and adrenal incidentaloma. Pheochromocytomas are rare tumours with fatal outcome if not duly recognized and cured.
Adrenocorticotrophin-dependent hypercortisolism: Imaging versus laboratory diagnosis
Tani?-GajiMilina,Vujovi? Svetlana,Ivovi? Miomira,Stojanovi? Milo?
Srpski Arhiv za Celokupno Lekarstvo , 2012, DOI: 10.2298/sarh1208500t
Abstract: Introduction. Cushing’s syndrome results from inappropriate exposure to excessive glucocorticoids. Untreated, it has significant morbidity and mortality. Case Outline. A 38-year-old woman with a typical appearance of Cushing’s syndrome was admitted for further evaluation of hypercortisolism. The serum cortisol level was elevated without diurnal rhythm, without adequate suppression of cortisol after 1 mg dexamethasone suppression test. 24-hour urinaryfree cortisol level was elevated. Differential diagnostic testing indicated adrenocorticotrophin (ACTH)- dependent lesion of the pituitary origin. Pituitary abnormalities were not observed during repeated MRI scanning. Inferior petrosal sinus sampling (IPSS) was performed: 1) Baseline ratio ACTH inferior petrosal sinus/peripheral was <2; 2) Corticotropin-releasing hormone (CRH) stimulated ratio ACTH inferior petrosal sinus/peripheral was <3; 3) Baseline intersinus ratio of ACTH was <1.4; 4) Increase in inferior petrosal sinus and peripheral ACTH of more than 50 percent above basal level after CRH; 5) Baseline ratio ACTH vena jugularis interna/peripheral was >1.7. Transsphenoidal exploration and removal of the pituitary tumor was performed inducing iatrogenic hypopituitarism. Postoperative morning serum cortisol level was less than 50 nmol/l on adequate replacement therapy with hydrocortisone, levothyroxine and estro-progestagen. Conclusion. No single test provides absolute distinction, but the combined results of several tests generally provide a correct diagnosis of Cushing’s syndrome.
Premature ovarian failure
Vujovi? Svetlana,Ivovi? Miomira,Tani?-GajiMilina,Marina Ljiljana
Srpski Arhiv za Celokupno Lekarstvo , 2012, DOI: 10.2298/sarh1212806v
Abstract: Premature ovarian failure (POF) is the occurrence of hypergonadotropic hypoestrogenic amenorrhea in women under the age of forty years. It is idiopathic in 74-90% patients. Known cases can be divided into primary and secondary POF. In primary POF genetic aberrations can involve the X chromosome (monosomy, trisomy, translocations, deletions) or autosomes. Genetic mechanisms include reduced gene dosage and non-specific chromosome effects impairing meiosis, decreasing the pool of primordial follicles and increasing atresia due to apoptosis or failure of follicle maturation. Autoimmune ovarian damage is caused by alteration of T-cell subsets and T-cell mediated injury, increase of autoantibody producing B-cells, a low number of effector/cytotoxic lymphocyte, which decreases the number and activity of natural killer cells. Bilateral oophorectomy, chemotherapy, radiotherapy and infections cause the secondary POF. Symptoms of POF include irritability, nervousness, loss of libido, depression, lack of concentration, hot flushes, weight gaining, dry skin, vaginal dryness, frequent infections etc. The diagnosis is confirmed by the level of FSH of over 40 IU/L and estradiol below 50 pmol/L in women aged below 40 years. Biochemical and other hormonal analysis (free thyroxin, TSH, prolactin, testosterone), karyotype (<30 years of age), ultrasound of the breasts and pelvis are advisable. Optimal therapy is combined estrogen progestagen therapy given in a sequential rhythm, after excluding absolute contraindications. Testosterone can be added to adnexectomized women and those with a low libido. Sequential estrogen progestagen replacement therapy is the first line therapy for ovulation induction in those looking for pregnancy and after that oocyte donation will be advised. Appropriate estro-progestagen therapy improves the quality of life and prevents complications such as cardiovascular diseases, osteoporosis, stroke etc.
Gaining weight and components of metabolic syndrome in the period of menopause
Simoncig-Netjasov Aleksandra,Vujovi? Svetlana,Ivovi? Miomira,Tani?-GajiMilina
Srpski Arhiv za Celokupno Lekarstvo , 2008, DOI: 10.2298/sarh0810505s
Abstract: INTRODUCTION Menopause induces redistribution of fat mass and development of abdominal obesity, increasing risk for metabolic syndrome (MS) by 60%. Related cardiovascular diseases become a leading cause of morbidity and mortality in women after fifty years of age. OBJECTIVE The aim of this study was to investigate the influence of gaining weight on components of MS in the menopause. METHOD The study included 50 obese women, BMI=31.92± 5.83 kg/m2, age 54.40±3.64, time since menopause 5.90±5.46 years, and 37 normal weight women, BMI=23.50±2.13 kg/m2, age 53.92±3.95, time since menopause 5.96±4.92 years. Both groups were divided according to the presence of MS into two subgroups. Anthropometric characteristics and blood pressure were measured. Blood was taken at 8 am for the following: fasting glucose, triglycerides, cholesterol, HDL, LDL, apolipoprotein A (ApoA), apolipoprotein B (ApoB), lipoprotein(a) (Lp(a)), C-reactive protein (CRP), fibrinogen, FSH, LH, prolactin, oestrogen, progesterone, testosterone and sex hormonebinding globulin (SHBG). RESULTS 66% of obese women had MS compared with 22% normal weight women. Significant differences between groups were found for the following: weight, BMI, waist, hip circumference, waist/hip ratio, diastolic blood pressure, Lp(a), FSH, LH, prolactin (all p<0.01) and fasting glucose (p<0.05). Obese women with and without MS were significantly diverse for the following: waist/hip ratio, systolic blood pressure and fasting glucose (all p<0.01); age, BMI, waist circumference, triglycerides, HDL, Lp(a) and SHBG (all p<0.05). Normal weight women with and without MS had significantly different values of waist/hip ratio, systolic, diastolic blood pressure, triglycerides (all p<0.01); HDL and testosterone (p<0.05). Significant differences were found between obese and normal weight women with MS in anthropometric characteristics, ApoA, Lp(a), fibrinogen (all p<0.01) and FSH (p<0.05). CONCLUSION Abdominal obesity significantly increases incidence of MS as a cluster of cardiovascular risk factors in the menopause.
Relationships between obesity, lipids and fasting glucose in the menopause
Simoncig-Netjasov Aleksandra,Vujovi? Svetlana,Ivovi? Miomira,Tani?-GajiMilina
Srpski Arhiv za Celokupno Lekarstvo , 2013, DOI: 10.2298/sarh1302041s
Abstract: Introduction. Menopause leads to the development of central adiposity, a more atherogenic lipid profile and increased incidence of metabolic syndrome independent of age and other factors. Objective. The aim of the study was to investigate the relationships between anthropometric characteristics, sex hormones, lipids and fasting glucose in menopausal women. Methods. The study included 87 menopausal women, who where divided into groups according to two criteria: BMI≥26.7 kg/m2 and BMI≥25 kg/m2. Anthropometric characteristics and blood pressure were measured. Blood was taken at 08.00 h for fasting glucose, triglycerides, cholesterol, HDL, LDL, apolipoprotein A, apolipoprotein B, lipoprotein(a) (Lp(a)), C-reactive protein, fibrinogen, follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), estradiol, progesterone, testosterone and sex hormone binding globulin (SHBG). Results. Significant differences between groups were found for weight, BMI, waist, hips circumference, waist/hip ratio (WHR), systolic and diastolic blood pressure, Lp(a), FSH, LH, PRL (for systolic blood pressure p<0.05, for the rest p<0.01) and fasting glucose (p<0.05). In obese and overweight women with BMI≥26.7kg/m2 significant negative correlations were found for FSH and glucose, SHBG and LDL, SHBG and total cholesterol, SHBG and glucose, BMI and HDL, WC and HDL. In obese and overweight women with BMI≥25kg/m2 significant negative correlations were found for BMI and HDL, waist circumference (WC) and HDL, WHR and HDL, FSH and glucose, SHBG and glucose; significant positive correlations were between BMI and glucose, WC and glucose and WHR with triglycerides. Conclusion. Gaining weight and decreased SHBG are related to dyslipidemia and increased fasting glucose confirming increased incidence of metabolic abnormalities in the menopause.
Influence of duration of menopause, anthropometric and hormonal parameters on metabolic syndrome
Simoncig-Netjasov Aleksandra,Vujovi? Svetlana,Ivovi? Miomira,Tani?-GajiMilina
Medicinski Pregled , 2010, DOI: 10.2298/mpns1002033s
Abstract: Introduction. Hypoestrogenic status in the menopausal women shows a shift to a central android fat distribution and metabolic syndrome (MS). Related metabolic changes and hypertension increase the risk for cardiovascular (CV) diseases. The aim of this study was to investigate the influence of duration of menopause, anthropometric and hormonal parameters on metabolic syndrome. Material and methods. 50 obese women were examined with BMI=31.92±5.83 kg/m2, age 54.40±3.64, time since menopause 5.90±5.46 years. Control group consisted of 37 normal weight women with BMI=23.50±2.13 kg/m2, age 53.92±3.95, time since menopause 5.96±4.92 years. Anthropometric characteristics and blood pressure were measured. Blood was taken at 8 am for: fasting glucose, triglycerides, cholesterol, HDL, LDL, apolipoprotein A (ApoA), apolipoprotein B (ApoB), lipoprotein(a) (Lp(a)), C-reactive protein (CRP), fibrinogen, FSH, LH, prolactin, estradiol, progesterone, testosterone and sex hormone binding globulin (SHBG). Results. In obese women significant negative correlations were found for: BMI and HDL (p<0,05), waist and HDL (p<0,05), FSH and systolic blood pressure (p<0.01), FSH and fasting glucose (p<0,05), LH and waist (p<0.05), SHBG and fasting glucose (p<0.05). A positive correlation was found for lime since meno-pause and waist/hip ratio (p<0.05). In controls positive correlations were found for: waist/hip ratio and systolic and diastolic blood pressure (p<0,05), LH and HDL (p<0.05), estradiol and diastolic blood pressure (p<0,05). Negative correlations were detected for estradiol and waist (p<0,05), time since menopause and HDL (p<0,05). Conclusion. Gaining weight together with menopausal endocrine changes cause metabolic and hemodynamic imbalances, which contribute to risk for cardiovascular diseases.
The testimony of the time: Aphorism
Ivanovi?-Bari?iMilina
Glasnik Etnografskog Instituta SANU , 2011, DOI: 10.2298/gei1102173i
Abstract: Short literary form known as aphorism in the beginning of its development relied on saying. Aphorism concisely expresses general experience, life philosophy, situation and position of a man in this world, socio-political and historical paradoxes etc. Although it is often taken as a criticism of society, it can also be understood as a testimony of time. This paper reveals one aspect of this phenomenon that was neglected by literary theory - aphorism as a form of expressing author’s attitude towards society and its reality.
Dress and fashion
Ivanovi?-Bari?iMilina
Glasnik Etnografskog Instituta SANU , 2006, DOI: 10.2298/gei0654245i
Abstract: Fashion is a contemporary phenomenon, with an increasing role in shaping behavior in contemporary societies. Fashion influences many areas of human creativity, especially mode of dressing. Dressing usually assumes traditional costume, which somewhat stayed static during history. Starting with Renaissance period, Europe experienced frequent changes in fashion styles (all changes came later to Serbia). In its beginnings, fashion was accepted mostly by wealthier classes, but in time, it gradually became available to general population, becoming so a part of the "consumers mentality". This availability of the fashion industry facilitates to many a brief, sharp cut with past in a short period of time. And while costume was characterized by certain stability of forms and materials, fashion represents a completely different phenomenon. That is, fashion is characterized by instability of forms and constant changes, and by relatively short periods of duration of styles and contemporary dressing.
Holiday text message well-wishing
Ivanovi?-Bari?iMilina
Glasnik Etnografskog Instituta SANU , 2008, DOI: 10.2298/gei0802075i
Abstract: Text messages became an important means of everyday communication, especially so among the younger generations. As a relatively new way of communication sending and receiving of text messages is shoving other, classical means such as letter writing. Sending a written message via cellular phone became usual means of communication in almost all life circumstances. This paper discusses messages sent out as well-wishing/cards for the most important yearly holidays.
Christianization of folk customs: An example of Ox'Church
Ivanovi?-Bari?iMilina
Glasnik Etnografskog Instituta SANU , 2009, DOI: 10.2298/gei0901175i
Abstract: This paper deals with the process of transformation of a pre-Christian custom in Zuce, a village near by Belgrade. The custom is called 'provlaka', held all until the WW II on August 29. This custom was established after the cattle pest in the village. Since WW II, however, this day is celebrated as the village St. patrons/slava day. After the village church has been built and blessed in 2002, the day became also celebrated as one of the church's slava days. Transformation of holidays assumes vanishing of some and appearance of some other segments of the given custom: 1. Until WW II the most important segment of the custom 'provlaka' was extracting wild fire and passage of people and cattle. This custom was maintained with an aim of preventive protection against epidemics. 2. A significant feature of annual celebration of calendar holidays included collective gatherings. On this day people visit relatives from other villages, attend lunch together, and gather at a particular village spot in the afternoon. 3. The beginning of the church building has allowed introduction of religious elements in celebration. In the morning, it is a time usually to attend a liturgy, while what follows represent some inherited customs like reception and eating together with relatives and friends. 4. After the village church has been built and blessed in 2002, the day became also celebrated as one of the church's slava days. This assumes presentation of the village cake maker and cake cutting in the church, accompanied by a local priest.
Page 1 /96149
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.