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Search Results: 1 - 10 of 15218 matches for " TANG Xiaowei "
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Molecular fluctuation in living cells
Xiaowei Tang
Science China Life Sciences , 1997, DOI: 10.1007/BF02879104
Abstract: The concept of molecular fluctuation in living cells is introduced. Many apparently different experimental facts in living cells, including the velocity non-uniformity of organelle movement, the saltatory movement of transport vesicles in axoplasmic transport, the chromosome oscillation during metaphase in mitosis and the pauses in the chromosome movement during anaphase are explained using a unified viewpoint. A method of determination of average number of the attached motor protein molecules from the experimental data is also proposed.
DISCUSSION ON THE LATERAL CONFINED DIFFUSION OF MEMBRANE PROTEINS
关于膜蛋白侧向限制扩散的讨论

Tang Xiaowei,
唐孝威

生物物理学报 , 1999,
Abstract: The difficulties of the membrane-skeleton fence model and the tethering model in explaining the lateral confined diffusion of membrane proteins were discussed. Based on the experimental face of one-dimensional constrained diffusion of proteins bound to the microtubules, the two-dimensional constrained diffuion model of the lateral diffusion of membrane proteins was proposed. Using this model the various modes of protein motion in the cell membrane were discussed.
Molecular fluctuation in living cells
TANG Xiaowei,
唐孝威

中国科学C辑(英文版) , 1997,
Abstract: The concept of molecular fluctuation in living cells is introduced. Many apparently different experi-mental facts in living cells, including the velocity non-uniformity of organelle movement, the saltatory movement of transport vesicles in axoplasmic transport, the chromosome oscillation during metaphase in mitosis and the pauses in the chromosome movement during anaphase are explained using a unified viewpoint. A method of determination of average number of the attached motor protein molecules from the experimental data is also proposed.
Mitotic dynamics
TANG Xiaowei,
唐孝威

中国科学C辑(英文版) , 1996,
Abstract: A new model for mitotic dynamics of eukaryotic cells is proposed. In the kinetochore mo-tor-midzone motor model two kinds of motors, the kinetochore motors and the midzone motors, play important roles in chromosome movement. Using this model the chromosome congression during prometaphase, the chromosome oscillation during metaphase and the chromatid segregation during anaphase are described in a unified way.
Rapid Diversification of FoxP2 in Teleosts through Gene Duplication in the Teleost-Specific Whole Genome Duplication Event
Xiaowei Song, Yajun Wang, Yezhong Tang
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0083858
Abstract: As one of the most conserved genes in vertebrates, FoxP2 is widely involved in a number of important physiological and developmental processes. We systematically studied the evolutionary history and functional adaptations of FoxP2 in teleosts. The duplicated FoxP2 genes (FoxP2a and FoxP2b), which were identified in teleosts using synteny and paralogon analysis on genome databases of eight organisms, were probably generated in the teleost-specific whole genome duplication event. A credible classification with FoxP2, FoxP2a and FoxP2b in phylogenetic reconstructions confirmed the teleost-specific FoxP2 duplication. The unavailability of FoxP2b in Danio rerio suggests that the gene was deleted through nonfunctionalization of the redundant copy after the Otocephala-Euteleostei split. Heterogeneity in evolutionary rates among clusters consisting of FoxP2 in Sarcopterygii (Cluster 1), FoxP2a in Teleostei (Cluster 2) and FoxP2b in Teleostei (Cluster 3), particularly between Clusters 2 and 3, reveals asymmetric functional divergence after the gene duplication. Hierarchical cluster analyses of hydrophobicity profiles demonstrated significant structural divergence among the three clusters with verification of subsequent stepwise discriminant analysis, in which FoxP2 of Leucoraja erinacea and Lepisosteus oculatus were classified into Cluster 1, whereas FoxP2b of Salmo salar was grouped into Cluster 2 rather than Cluster 3. The simulated thermodynamic stability variations of the forkhead box domain (monomer and homodimer) showed remarkable divergence in FoxP2, FoxP2a and FoxP2b clusters. Relaxed purifying selection and positive Darwinian selection probably were complementary driving forces for the accelerated evolution of FoxP2 in ray-finned fishes, especially for the adaptive evolution of FoxP2a and FoxP2b in teleosts subsequent to the teleost-specific gene duplication.
Resting state brain activity and functional brain mapping
Zhao Xiaohu,Wang Peijun,Tang Xiaowei,
Zhao Xiaohu
,Wang Peijun and Tang Xiaowei

自然科学进展 , 2007,
Abstract: Functional brain imaging studies commonly use either resting or passive task states as their control conditions, and typically identify the activation brain region associated with a specific task by subtracting the resting from the active task conditions. Numerous studies now suggest, however, that the resting state may not reflect true mental "rest" conditions. The mental activity that occurs during "rest" might therefore greatly influence the functional neuroimaging observations that are collected through the usual subtracting analysis strategies. Exploring the ongoing mental processes that occur during resting conditions is thus of particular importance for deciphering functional brain mapping results and obtaining a more comprehensive understanding of human brain functions. In this review article, we will mainly focus on the discussion of the current research background of functional brain mapping at resting state and the physiological significance of the available neuroimaging data.
The Risk Premium of Treasury Bonds in China  [PDF]
Xiaowei Wu
Journal of Mathematical Finance (JMF) , 2016, DOI: 10.4236/jmf.2016.61015
Abstract:

This paper studied the macroeconomic and the term structure of treasury bonds in the Shanghai Stock Exchange Market. Different from previous studies, we used a group of 122 observed macroeconomic data to construct our model’s macro factor. Therefore the macro factor contained more information than previous studies in predicting the excess return of Treasury bond. Based on the Kalman-Filter estimation, the results show that the macro factor’s risk was compensated through the level factor and slope factor, especially the level factor. Further, based on the decomposition of the yield curve into expected future short rate part and risk premium part, we find that there is some correlation between the variability of the risk premium and monetary policy to some extent.

Roles for microtubule and microfilament cytoskeletons in animal cell cytokinesis
Zhongcai Chen,Shang Cai,Qing Jiang,Chuanmao Zhang,Xiaowei Tang
Chinese Science Bulletin , 2005, DOI: 10.1007/BF02897532
Abstract: Microtubule and microfilament cytoskeletons play key roles in the whole process of cytokinesis. Although a number of hypotheses have been proposed to elucidate the mechanism of cytokinesis by microtubule and actin filament cytoskeletons, many reports are conflicting. In our study, combining the cytoskeletons drug treatments with the time-lapse video technology, we retested the key roles of microtubule and actin filament in cytokinesis. The results showed that depolymerization of microtubules by Nocodazole after the initiation of furrowing would not inhibit the furrow ingression, but obviously decrease the stiffness of daughter cells. Depolymerizing actin filaments by Cytochalasin B before metaphase would inhibit the initiation of furrowing but not chromosome segregation, resulting in the formation of binucleate cells; however, depolymerizing actin filaments during anaphase would prevent furrowing and lead to the regress of established furrow, also resulting in the formation of binucleate cells. Further, depolymerizing microtubules and actin filaments simultaneously after metaphase would cause the quick regress of the furrow and the formation of binucleate cells. From these results we propose that a successful cytokinesis requires functions and coordination of both the microtubule and actin filament cytoskeletons. Microtubule cytoskeleton may function in the positioning and initiation of cleavage furrow, and the actin filament cytoskeleton may play key roles in the initiation and ingression of the furrow.
Three-dimensional reconstruction and analysis of structure characteristics on senile plaques of Alzheimer’s disease
Ye Wei,Liu Jianwu,Zhou Jiangning,Hu Xiangyou,Tang Xiaowei
Chinese Science Bulletin , 2005, DOI: 10.1007/BF02897380
Abstract: Alzheimer’s disease is a progressive neurodegenerative disorder characterized by the presence of senile plaques primarily composed of amyloid β in brain. Abnormal secretion and aggregation of amyloid β are the key events in pathogenesis of Alzheimer’s disease. Reduction of amyloid β production and inhibition of amyloid β aggregation to form senile plaques are hopeful strategies for the treatment and prevention of Alzheimer’s disease. In the present study, the silver and immunohistochemical staining methods were applied to discover senile plaques in the hippocampus of Alzheimer’s disease patients, and then images were processed and three-dimensionally reconstructed by Matlab and AVS software. The structure characteristics of senile plaques were measured through correlation function calculation and fractal dimension by a computer-aided method. Diffuse plaque had no amyloid center, but classic plaque presented compact central core structure; two types of plaques were both of porous structure, but the sizes of their pores were significantly different. Furthermore, there was difference in fractal dimension value between the diffuse plaque and classic plaque in the two staining methods. The comparison of structure characteristics between two types of plaques indicated that they developed independently. Establishment of the methods for reconstructing the three-dimensional structure of senile plaque and analyzing their structure characteristics is helpful for further study on the aggregation mechanism of senile plaque.
L2-LBMT:A Layered Load Balance Routing Protocol for Underwater Multimedia Data Transmission L2-LBMT:A Layered Load Balance Routing Protocol for Underwater Multimedia Data Transmission
LV Ze,TANG Ruichun,TAO Ye,SUN Xin,XU Xiaowei
- , 2017,
Abstract: Providing highly efficient underwater transmission of mass multimedia data is challenging due to the particularities of the underwater environment. Although there are many schemes proposed to optimize the underwater acoustic network communication protocols, from physical layer, data link layer, network layer to transport layer, the existing routing protocols for underwater wireless sensor network(UWSN) still cannot well deal with the problems in transmitting multimedia data because of the difficulties involved in high energy consumption, low transmission reliability or high transmission delay. It prevents us from applying underwater multimedia data to real-time monitoring of marine environment in practical application, especially in emergency search, rescue operation and military field. Therefore, the inefficient transmission of marine multimedia data has become a serious problem that needs to be solved urgently. In this paper, A Layered Load Balance Routing Protocol(L2-LBMT) is proposed for underwater multimedia data transmission. In L2-LBMT, we use layered and load-balance Ad Hoc Network to transmit data, and adopt segmented data reliable transfer(SDRT) protocol to improve the data transport reliability. And a 3-node variant of tornado(3-VT) code is also combined with the Ad Hoc Network to transmit little emergency data more quickly. The simulation results show that the proposed protocol can balance energy consumption of each node, effectively prolong the network lifetime and reduce transmission delay of marine multimedia data
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