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Search Results: 1 - 10 of 118027 matches for " T. Suda "
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How Quantum Mechanics and General Relativity Can Be Brought Together  [PDF]
Martin Suda
Journal of Modern Physics (JMP) , 2016, DOI: 10.4236/jmp.2016.76054
Abstract: This paper describes an easy and teaching way how quantum mechanics (QM) and general relativity (GR) can be brought together. The method consists of formulating Schr?dinger’s equation of a free quantum wave of a massive particle in curved space-time of GR using the Schwarzschild metric. The result is a Schr?dinger equation of the particle which is automatically subjected to Newtons’s gravitational potential.
Procalcitonin level as a marker of severe sepsis and septic shock patients who required polymyxin-B immobilized fiber with direct hemoperfusion
T Ikeda, K Ikeda, S Suda
Critical Care , 2012, DOI: 10.1186/cc11692
Abstract: We evaluated the levels of procalcitonin (PCT) and markers of sepsis (IL-6, IL-8, IL-1ra and PAI-1) in 159 patients who had severe sepsis and septic shock. Before starting the polymyxin-B immobilized fiber with direct hemoperfusion (PMX-DHP) treatment, patients were divided into three groups according to their PCT levels (L group: 0.5 10.0 ng/ml).Sixty-two percent of the patients showed high PCT levels (>10.0 ng/ml). The APACHE II score and Sequential Organ Failure Assessment score tended to be high in the H group, but there was no significant difference among the groups. The survival rate declined with high PCT levels. The levels of inflammatory (IL-6 and IL-8) and anti-inflammatory (IL-1ra) cytokines tended to be high in the H group, but there was no statistically significant difference among the groups. On the other hand, the PAI-1 level was significantly increased in the H group (498 ± 499 ng/ml) compared with the L group (157 ± 103 ng/ml) and M group (311 ± 319 ng/ml).Sixty-two per cent of patients who required PMX-DHP treatment had high PCT levels. PCT might be a mediator of sepsis and sepsis markers. PCT can potentially affect sepsis-related markers.
Computation of Greeks Using Binomial Tree  [PDF]
Yoshifumi Muroi, Shintaro Suda
Journal of Mathematical Finance (JMF) , 2017, DOI: 10.4236/jmf.2017.73031
Abstract: This paper proposes a new efficient algorithm for the computation of Greeks for options using the binomial tree. We also show that Greeks for European options introduced in this article are asymptotically equivalent to the discrete version of Malliavin Greeks. This fact enables us to show that our Greeks converge to Malliavin Greeks in the continuous time model. The computation algorithm of Greeks for American options using the binomial tree is also given in this article. There are three advantageous points to use binomial tree approach for the computation of Greeks. First, mathematics is much simpler than using the continuous time Malliavin calculus approach. Second, we can construct a simple algorithm to obtain the Greeks for American options. Third, this algorithm is very efficient because one can compute the price and Greeks (delta, gamma, vega, and rho) at once. In spite of its importance, only a few previous studies on the computation of Greeks for American options exist, because performing sensitivity analysis for the optimal stopping problem is difficult. We believe that our method will become one of the popular ways to compute Greeks for options.
Influence of Gravitational Waves on Circular Moving Particles  [PDF]
Manfried Faber, Martin Suda
Journal of Modern Physics (JMP) , 2018, DOI: 10.4236/jmp.2018.94045
Abstract: We investigate the influence of a gravitational wave background on particles in circular motion. We are especially interested in waves leading to stationary orbits. This consideration is limited to circular orbits perpendicular to the incidence direction. As a main result of our calculation, we obtain in addition to the well-known alteration of the radial distance a time dependent correction term for the phase modifying the circular motion of the particle. A background of gravitational waves creates some kind of uncertainty.
The molecular mechanism of osteoclastogenesis: ODF/RANKL-dependent and independent pathways
T Suda, N Takahashi, N Udagawa, C Miyaura
Arthritis Research & Therapy , 2001, DOI: 10.1186/ar168
Abstract: IL-1 and TNFα also play a major role in the pathogenesis of bone resorption induced by inflammation. IL-1 induced osteoclast differentiation by a classical ODF/RANKL-dependent mechanism, indicating that osteoblasts are essential for IL-1-induced osteoclast formation. In contrast, mouse TNFα strongly stimulated differentiation of M-CSF-dependent bone marrow macrophages (M-BMMφ) into osteoclasts without any help of osteoblasts/stromal cells. Osteoclast formation by TNFα was inhibited by antibodies against TNF receptor type 1 and 2 (TNFR1 and TNFR2), but not by OPG/OCIF, indicating that differentiation of M-BMMφ into osteoclasts by TNFα occurs by a mechanism independent of the ODF/RANKL-RANK interaction. IL-1 failed to induce differentiation of M-BMMφ into osteoclasts.More recently, we found that lipopolysaccharides (LPS)-induced bone loss did not occur in knockout mice of EP4, a subtype of PGE2 receptor. This indicates that EP4 signals are involved in the LPS-induced bone resorption. LPS appeared to induce osteoclast formation by two different pathways: one is an ODF/RANK-independent pathway involving TNFα. LPS induces TNFα production through toll-like receptor 4 (TLR4) in macrophages, which in turn directly acts on osteoclast progenitors through TNFR1 and TNFR2 to induce osteoclast differentiation. In this pathway, osteoblasts did not appear to be involved. The other pathway is the classical ODF/RANKL-dependent pathway. In the classical pathway, LPS induces PGE2 production through TLR4 in osteoblasts and macrophages, which in turn induces ODF/RANKL through EP4 in osteoblasts. ODF then binds ODF receptor (RANK) in osteoclast progenitors by cell-cell contact, which stimulates osteoclast differentiation.We conclude that osteoblasts/stromal cells are involved in not only physiological, but also pathological bone resorption via ODF/RANKL.
New sepsis-related marker: endotoxin activity assay
T Ikeda, K Ikeda, H Taniuchi, M Hiramatsu, S Suda
Critical Care , 2010, DOI: 10.1186/cc9115
Abstract: The EAA was studied in a cohort of 153 septic patients admitted to the ICU. At the same time, IL-6 (chemiluminescent enzyme immunoassay), C-reactive protein (CRP), procalcitonin (PCT, chemiluminescent enzyme immunoassay) and plasminogen activator inhibitor-1 (PAI-1, latex photometric immunoassay) were measured within 24 hours after ICU admission. The patients were divided into the following three groups: L group: EAA < 0.4, M group: 0.4 ≤ EAA < 0.6, H group: 0.6 ≤ EAA. Nonrepeated-measures ANOVA was used to compare over three groups or conditions. Statistical significance was assumed for values of P < 0.05. Normally distributed data are presented as mean ± SD, and abnormally distributed data are presented as median values.Of the 153 patients, the L group contained 61 patients, M group 41 patients, and H group 51 patients, respectively. On the day of ICU admission, the rate of EAA ≥0.4 was 60.1% (MEDIC study: 57.2%). APACHE score in the L group was 21.0 ± 7.9, M group 24.8 ± 8.4, H group 26.4 ± 8.9, and SOFA score in the L group was 8.2 ± 4.3, M group 8.9 ± 4.1, H group 9.5 ± 4.3, respectively. There was no statistically significant difference among the groups. The median value of PCT in the L group was 1.1 ng/ml, M group 5.9 ng/ml, H group 8.5 ng/ml, respectively. PCT values of the M and H groups were significantly higher than those of the L group. Median IL-6 level of the H group was significantly higher than that of the L group (H group: 2,635 pg/ml, L group: 177 pg/ml).EAA has no significant correlation with other sepsis-related markers, but may be associated with body insults (inflammation or infection).
A Design of an Autonomous Molecule Loading/Transporting/Unloading System Using DNA Hybridization and Biomolecular Linear Motors
Satoshi Hiyama,Y. Isogawa,T. Suda,Y. Moritani,Kazuo Sutoh
Physics , 2007,
Abstract: This paper describes a design of a molecular propagation system in molecular communication. Molecular communication is a new communication paradigm where biological and artificially-created nanomachines communicate over a short distance using molecules. A molecular propagation system in molecular communication directionally transports molecules from a sender to a receiver. In the design described in this paper, protein filaments glide over immobilized motor proteins along preconfigured microlithographic tracks, and the gliding protein filaments carry and transport molecules from a sender to a receiver. In the design, DNA hybridization is used to load and unload the molecules onto and from the carriers at a sender and a receiver. In the design, loading/transporting/unloading processes are autonomous and require no external control.
SAGA: Stellar Abundances for Galactic Archaeology
Takuma Suda
Physics , 2012,
Abstract: A tutorial for the Stellar Abundances for Galactic Archaeology (SAGA) database is presented. This paper describes the outline of the database, reports the current status of the data compilation and known problems, and presents plans for future updates and extensions.
Coherent configurations and triply regular association schemes obtained from spherical designs
Sho Suda
Mathematics , 2009,
Abstract: Delsarte-Goethals-Seidel showed that if $X$ is a spherical $t$-design with degree $s$ satisfying $t\geq 2s-2$, $X$ carries the structure of an association scheme. Also Bannai-Bannai showed that the same conclusion holds if $X$ is an antipodal spherical $t$-design with degree $s$ satisfying $t=2s-3$. As a generalization of these results, we prove that a union of spherical designs with a certain property carries the structure of a coherent configuration. We derive triple regularity of tight spherical $4,5,7$-designs, mutually unbiased bases, linked symmetric designs with certain parameters.
Trace formulas of the Hecke operator on the spaces of newforms
Suda Tomohiko
Mathematics , 2011,
Abstract: In this paper, for a square-free integer l>1, a even positive integer k and a positive integer N, we give a trace formula of the Hecke operator T(l) on the space S_k^0(N) of all newforms of weight k and level \Gamma_0(N). Moreover, we give a decomposition S_k^0(N)=\oplus_{i|N}S_k^0(N;i) and also give a trace formula of T(l) on S_k^0(N;i).
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