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Search Results: 1 - 10 of 117894 matches for " T. Schlossbauer "
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Evaluation of a Nonrigid Motion Compensation Technique Based on Spatiotemporal Features for Small Lesion Detection in Breast MRI
F. Steinbruecker,A. Meyer-Baese,T. Schlossbauer,D. Cremers
Advances in Artificial Neural Systems , 2012, DOI: 10.1155/2012/808602
Abstract: Motion-induced artifacts represent a major problem in detection and diagnosis of breast cancer in dynamic contrast-enhanced magnetic resonance imaging. The goal of this paper is to evaluate the performance of a new nonrigid motion correction algorithm based on the optical flow method. For each of the small lesions, we extracted morphological and dynamical features describing both global and local shape, and kinetics behavior. In this paper, we compare the performance of each extracted feature set under consideration of several 2D or 3D motion compensation parameters for the differential diagnosis of enhancing lesions in breast MRI. Based on several simulation results, we determined the optimal motion compensation parameters. Our results have shown that motion compensation can improve the classification results. The results suggest that the computerized analysis system based on the non-rigid motion compensation technique and spatiotemporal features has the potential to increase the diagnostic accuracy of MRI mammography for small lesions and can be used as a basis for computer-aided diagnosis of breast cancer with MR mammography. 1. Introduction Breast cancer is one of the leading death cases among women in the US. MR technology has advanced tremendously and became a highly sensitive method for the detection of invasive breast cancer [1]. While only dynamic signal intensity characteristics are integrated in today's CAD systems leaving morphological features to the interpretation of the radiologist, an automated diagnosis based on a combination of both should be strived for. Clinical studies have shown that combinations of different dynamic and morphologic characteristics [2] achieve diagnostic sensitivities up to 97 % and specificities up to 76.5 % . However, most of these techniques have not been applied to small enhancing foci having a size of less than 1?cm. These diagnostically challenging cases found unclear ultrasound or mammography indications can be adequately visualized in magnetic resonance imaging (MRI) [3] with MRI providing an accurate estimation of invasive breast cancer tumor size [4]. Automatic motion correction represents an important prerequisite to a correct automated small lesion evaluation [5]. Motion artifacts are caused either by the relaxation of the pectoral muscle or involuntary patient motion and invalidate the assumption of same spatial location within the breast of the corresponding voxels in the acquired volumes for assessing lesion enhancement. Especially for small lesions, the assumption of correct spatial alignment often
Small Lesions Evaluation Based on Unsupervised Cluster Analysis of Signal-Intensity Time Courses in Dynamic Breast MRI
A. Meyer-Baese,T. Schlossbauer,O. Lange,A. Wismueller
International Journal of Biomedical Imaging , 2009, DOI: 10.1155/2009/326924
Abstract: An application of an unsupervised neural network-based computer-aided diagnosis (CAD) system is reported for the detection and characterization of small indeterminate breast lesions, average size 1.1 mm, in dynamic contrast-enhanced MRI. This system enables the extraction of spatial and temporal features of dynamic MRI data and additionally provides a segmentation with regard to identification and regional subclassification of pathological breast tissue lesions. Lesions with an initial contrast enhancement ≥50% were selected with semiautomatic segmentation. This conventional segmentation analysis is based on the mean initial signal increase and postinitial course of all voxels included in the lesion. In this paper, we compare the conventional segmentation analysis with unsupervised classification for the evaluation of signal intensity time courses for the differential diagnosis of enhancing lesions in breast MRI. The results suggest that the computerized analysis system based on unsupervised clustering has the potential to increase the diagnostic accuracy of MRI mammography for small lesions and can be used as a basis for computer-aided diagnosis of breast cancer with MR mammography.
Selection of Spatiotemporal Features in Breast MRI to Differentiate between Malignant and Benign Small Lesions Using Computer-Aided Diagnosis
F. Steinbruecker,A. Meyer-Baese,C. Plant,T. Schlossbauer,U. Meyer-Baese
Advances in Artificial Neural Systems , 2012, DOI: 10.1155/2012/919281
Abstract: Automated detection and diagnosis of small lesions in breast MRI represents a challenge for the traditional computer-aided diagnosis (CAD) systems. The goal of the present research was to compare and determine the optimal feature sets describing the morphology and the enhancement kinetic features for a set of small lesions and to determine their diagnostic performance. For each of the small lesions, we extracted morphological and dynamical features describing both global and local shape, and kinetics behavior. In this paper, we compare the performance of each extracted feature set for the differential diagnosis of enhancing lesions in breast MRI. Based on several simulation results, we determined the optimal feature number and tested different classification techniques. The results suggest that the computerized analysis system based on spatiotemporal features has the potential to increase the diagnostic accuracy of MRI mammography for small lesions and can be used as a basis for computer-aided diagnosis of breast cancer with MR mammography. 1. Introduction Breastcancer is one of the most common cancers among women. Contrast-enhanced MR imaging of the breast was reported to be a highly sensitive method for the detection of invasive breast cancer [1]. Different investigators described that certain dynamic signal intensity (SI) characteristics (rapid and intense contrast enhancement followed by a wash out phase) obtained in dynamic studies are a strong indicator for malignancy [2]. Morphologic criteria have also been identified as valuable diagnostic tools [3]. Recently, combinations of different dynamic and morphologic characteristics have been reported [4] that can reach diagnostic sensitivities up to 97 and specificities up to 76.5 . As an important aspect remains the fact that many of these techniques were applied on a database of predominantly tumors of a size larger than 2?cm. In these cases, MRI reaches a very high sensitivity in the detection of invasive breast cancer due to both morphological criteria as well as characteristic time-signal intensity curves. However, the value of dynamic MRI and of automatic identification and classification of characteristic kinetic curves is not well established in small lesions when clinical findings, mammography, and ultrasound are unclear. Recent clinical research has shown that DCIS with small invasive carcinoma can be adequately visualized in MRI [5] and that MRI provides an accurate estimation of invasive breast cancer tumor size, especially in tumors of 2?cm or smaller [6]. Visual assessment of
REGULARYFRAMWORK AND LEGAL BASE OF ELECTRONIC DOCUMENT CIRCULATION НОРМАТИВНО-ПРАВОВА БАЗА ЕЛЕКТРОННОГО ДОКУМЕНТООБ ГУ
T.Г. Омельченко,Н.А. Джанджгава
Information Technologies and Learning Tools , 2010,
Abstract: The general characteristic of legal base of electronic document circulation is presented in the article. It legislatively regulates the relations which connected with the information and information communication technologies. There is presented the list of the basic acts of regulation of sphere of information relations. У робот подано загальну характеристику нормативно-правово бази, яка законодавчо регулю в дносини, пов'язан з нформац ю, нформац йно-комун кац йними технолог ями, представлено перел к основних законодавчих акт в регулювання сфери нформац йних в дносин.
THE APPROACH OF COMPETENCE AT THE STUDY OF MATHEMATICAL INFORMATICS IN A PEDAGOGICAL UNIVERSITY КОМПЕТЕНТН СНИЙ П ДХ Д ПРИ ВИВЧЕНН МАТЕМАТИЧНО НФОРМАТИКИ” У ПЕДАГОГ ЧНОМУ УН ВЕРСИТЕТ
T.П. Кобильник
Information Technologies and Learning Tools , 2010,
Abstract: In the paper the approach of competence at the study of mathematical informatics in a pedagogical university is considered. The special attention is paid to forming of professional pedagogical and educational-cognitive competences. The example of tasks on which formed a competence at the study of mathematical informatics is resulted. У статт розглянуто компетентн сний п дх д при вивченн математично нформатики у педагог чному ун верситет . Особливу увагу звернено на формування профес йно педагог чно та навчально-п знавальну компетентност . Наведено приклад завдань, як сприяють формуванню компетентностей при вивченн математично нформатики.
SYSTEM OF THE AUTOMATIC DOCUMENT PROCESSING IN SHELL OF BASE SOFTWARE СИСТЕМА АВТОМАТИЗОВАНОГО ДОКУМЕНТООБ ГУ В ОБОЛОНЦ БАЗОВОГО ПРОГРАМНОГО ЗАБЕЗПЕЧЕННЯ
В.Ю. Биков,T.О. Дерба
Information Technologies and Learning Tools , 2010,
Abstract: In the article the automatic system of the document processing, created with use of Microsoft Access – a component part of Microsoft Office is offered. This system can be used at school and Institutions of education with one computer or with system of 15 ones connecting in the local net. У статт запропоновано для ознайомлення автоматизовану систему документооб гу, створену з використанням Microsoft Access – складово частини Microsoft Office. Ця система може використовуватися в школах установах осв тньо галуз на одному комп’ютер чи на систем до 15 комп’ютер в, пов’язаних локальною мережею.
MODERN APPROACHES AND PRINCIPLES OF PORTAL BUILDING ТЕХНОЛОГ ЧН ОСНОВИ СТВОРЕННЯ ТА П ДТРИМКИ ПОРТАЛ В
Н.Т. Задорожна,T.Г. Омельченко
Information Technologies and Learning Tools , 2010,
Abstract: The paper presents the analysis of modern state of development and use of Internet portals, the peculiarities of approaches to creation and introduction of portals in educational system are described. В робот анал зуються принципи розробки та використання нтернет-портал в, описуються особливост п дход в до створення та впровадження портал в у систему осв ти.
REVIEW OF MODERN TOOLS OF INFORMATION AND COMMUNICATION TECHNOLOGIES IN THE MANAGEMENT OF SECONDARY EDUCATION ОГЛЯД СУЧАСНИХ ЗАСОБ В НФОРМАЦ ЙНО-КОМУН КАЦ ЙНИХ ТЕХНОЛОГ Й В УПРАВЛ НН СЕРЕДНЬОЮ ОСВ ТОЮ
T.О. Дерба
Information Technologies and Learning Tools , 2010,
Abstract: There are presented the up-to-date situation with information and communication technology use in the management of secondary education; information and communication technologies (ICT), that practically used in educational establishments are considered. There are some examples of educational institutions using IСT for the automation of management. У статт показаний зр з сучасного стану використання нформац йно-комун кац йних технолог й в управл нн середньою осв тою, розглянут нформац йно-комун кац йн технолог ( КТ), як на практиц використовуються в загальноосв тн х закладах, наведен в дгуки навчальних заклад в, як використовують КТ для автоматизац управл ння
EVALUATION OF INTEGRALS OF FUNCTIONS OF COMPLEX VARIABLE BY USING THE RESIDUES IN COMPUTER MATHEMATICS SYSTEMS ОБЧИСЛЕННЯ НТЕГРАЛ В В Д ФУНКЦ Й КОМПЛЕКСНО ЗМ ННО ЗА ДОПОМОГОЮ ЗАЛИШК В В СИСТЕМАХ КОМП’ЮТЕРНО МАТЕМАТИКИ
Н.Д. Парфьонова,T.В. Клочко
Information Technologies and Learning Tools , 2010,
Abstract: The article describes the methodology of teaching one of the major topics of the course of complex analysis using the system Maple. It also demonstrates how the use of computer mathematics systems facilitates the evaluation of students by the teacher during organization of independent work. В статт наведено методику викладання мабуть одн з найважлив ших тем курсу комплексного анал зу з використанням системи Maple; демонстру ться, як використання систем комп’ютерно математики полегшу викладачев оц нювання роботи студент в та при орган зац х самост йно роботи.
USE OF VEB 2.0 SOCIAL SERVICES FOR PLANNING OF INFORMATIVE SYSTEMS ВИКОРИСТАННЯ СОЦ АЛЬНИХ СЕРВ С В ВЕБ 2.0 ДЛЯ ПРОЕКТУВАННЯ НФОРМАЦ ЙНИХ СИСТЕМ
T.Г. Омельченко
Information Technologies and Learning Tools , 2010,
Abstract: In the article the definitions and the characteristic of Web 2.0 social networks and services are presented as well as tendencies of their development, approaches of use of Web 2.0 social services and technologies in information systems are considered and analyzed. Requirements to technological maintenance of information system “Planning of scientific researches in NPA of Ukraine” are analyzed. В робот представлен визначення характеристика соц альних мереж послуг Веб 2.0 та тенденц хнього розвитку, розглянуто проанал зовано напрямки використання соц альних послуг та технолог й Веб 2.0 в нформац йних системах. Проанал зовано вимоги до технолог чного забезпечення нформац йно системи “Планування наукових досл джень в АПН Укра ни”.
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