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DESIGN AND CHARACTERIZATION OF CLARITHROMYCIN BEADS USING A BIODEGRADABLE CATIONIC POLYMER
P Jeyaprabha,T Sudhamani
International Research Journal of Pharmacy , 2013, DOI: 10.7897/2230-8407.04337
Abstract: The objective of the present study was to prepare clarithromycin beads by ionotropic gelation method using cationic polymer. Infra red spectroscopy study showed that the drug and excipients were compatible with each other. The beads were evaluated for SEM, average particle size, swelling studies, zeta potential, drug entrapment and in vitro drug release. The average particle size of the beads was between 0.87±0.020 and 1.254±0.030mm.The swelling ratio was greater in buffer pH 1.2 and the zeta potential values showed positive charge of the beads. The in vitro release study showed that the drug release was found to follow first order diffusion controlled release.
PREPARATION AND EVALUATION OF ETHYL CELLULOSE MICROSPHERES OF IBUPROFEN FOR SUSTAINED DRUG DELIVERY.
T.Sudhamani
International Journal of Pharmaceutical Research and Development , 2010,
Abstract: Ibuprofen, a non-steroidal anti-inflammatory drug was formulated as microspheres by using ethylcellulose as carrier. These ethylcellulose microspheres were prepared by the solvent evaporation method. The prepared microspheres were subjected to various evaluation and invitro release studies. Highest percentage of loading was obtained by increasing the amount of ibuprofen with respect to polymer. The particle sizes of the prepared microspheres were determined by optical microscopy and SEM analysis. The prepared microspheres had good spherical geometry with smooth surface as evidence by SEM. The invitro release studies showed that ibuprofen microspheres of 1:2 ratios showed better sustained effect over a period of 8 hours.
Molecular interaction studies of glycylglycine in aqueous sodium halide solutions at 303, 308 and 313k
R. Palani,S. Balakrishnan,K. A. Sudhamani
Journal of Engineering and Applied Sciences , 2010,
Abstract: Ultrasonic velocity, density and viscosity have been measured for glycylglycine in aqueous sodium halide (NaF, NaCl, NaBr) mixture (0.5m) at 303, 308 and 313K. Using the experimental values, the adiabatic compressibility, hydration number, apparent molal compressibility, apparent molal volume, limiting apparent molal compressibility, limiting apparent molal volume and their constants (SK, SV), transfer volumes at infinite dilution and viscosity B-coefficient of Jones-Dole equation were calculated. These parameters have been interpreted the molecular interactions in terms of solute-co-solute and solute-solvent interaction present in the given solutions.
Lipoleiomyoma of uterus: A case report with review of literature
Sudhamani S,Agrawal Durgaprasad,Pandit Ajita,Kiri V
Indian Journal of Pathology and Microbiology , 2010,
Abstract:
REGULARYFRAMWORK AND LEGAL BASE OF ELECTRONIC DOCUMENT CIRCULATION НОРМАТИВНО-ПРАВОВА БАЗА ЕЛЕКТРОННОГО ДОКУМЕНТООБ ГУ
T.Г. Омельченко,Н.А. Джанджгава
Information Technologies and Learning Tools , 2010,
Abstract: The general characteristic of legal base of electronic document circulation is presented in the article. It legislatively regulates the relations which connected with the information and information communication technologies. There is presented the list of the basic acts of regulation of sphere of information relations. У робот подано загальну характеристику нормативно-правово бази, яка законодавчо регулю в дносини, пов'язан з нформац ю, нформац йно-комун кац йними технолог ями, представлено перел к основних законодавчих акт в регулювання сфери нформац йних в дносин.
THE APPROACH OF COMPETENCE AT THE STUDY OF MATHEMATICAL INFORMATICS IN A PEDAGOGICAL UNIVERSITY КОМПЕТЕНТН СНИЙ П ДХ Д ПРИ ВИВЧЕНН МАТЕМАТИЧНО НФОРМАТИКИ” У ПЕДАГОГ ЧНОМУ УН ВЕРСИТЕТ
T.П. Кобильник
Information Technologies and Learning Tools , 2010,
Abstract: In the paper the approach of competence at the study of mathematical informatics in a pedagogical university is considered. The special attention is paid to forming of professional pedagogical and educational-cognitive competences. The example of tasks on which formed a competence at the study of mathematical informatics is resulted. У статт розглянуто компетентн сний п дх д при вивченн математично нформатики у педагог чному ун верситет . Особливу увагу звернено на формування профес йно педагог чно та навчально-п знавальну компетентност . Наведено приклад завдань, як сприяють формуванню компетентностей при вивченн математично нформатики.
SYSTEM OF THE AUTOMATIC DOCUMENT PROCESSING IN SHELL OF BASE SOFTWARE СИСТЕМА АВТОМАТИЗОВАНОГО ДОКУМЕНТООБ ГУ В ОБОЛОНЦ БАЗОВОГО ПРОГРАМНОГО ЗАБЕЗПЕЧЕННЯ
В.Ю. Биков,T.О. Дерба
Information Technologies and Learning Tools , 2010,
Abstract: In the article the automatic system of the document processing, created with use of Microsoft Access – a component part of Microsoft Office is offered. This system can be used at school and Institutions of education with one computer or with system of 15 ones connecting in the local net. У статт запропоновано для ознайомлення автоматизовану систему документооб гу, створену з використанням Microsoft Access – складово частини Microsoft Office. Ця система може використовуватися в школах установах осв тньо галуз на одному комп’ютер чи на систем до 15 комп’ютер в, пов’язаних локальною мережею.
MODERN APPROACHES AND PRINCIPLES OF PORTAL BUILDING ТЕХНОЛОГ ЧН ОСНОВИ СТВОРЕННЯ ТА П ДТРИМКИ ПОРТАЛ В
Н.Т. Задорожна,T.Г. Омельченко
Information Technologies and Learning Tools , 2010,
Abstract: The paper presents the analysis of modern state of development and use of Internet portals, the peculiarities of approaches to creation and introduction of portals in educational system are described. В робот анал зуються принципи розробки та використання нтернет-портал в, описуються особливост п дход в до створення та впровадження портал в у систему осв ти.
REVIEW OF MODERN TOOLS OF INFORMATION AND COMMUNICATION TECHNOLOGIES IN THE MANAGEMENT OF SECONDARY EDUCATION ОГЛЯД СУЧАСНИХ ЗАСОБ В НФОРМАЦ ЙНО-КОМУН КАЦ ЙНИХ ТЕХНОЛОГ Й В УПРАВЛ НН СЕРЕДНЬОЮ ОСВ ТОЮ
T.О. Дерба
Information Technologies and Learning Tools , 2010,
Abstract: There are presented the up-to-date situation with information and communication technology use in the management of secondary education; information and communication technologies (ICT), that practically used in educational establishments are considered. There are some examples of educational institutions using IСT for the automation of management. У статт показаний зр з сучасного стану використання нформац йно-комун кац йних технолог й в управл нн середньою осв тою, розглянут нформац йно-комун кац йн технолог ( КТ), як на практиц використовуються в загальноосв тн х закладах, наведен в дгуки навчальних заклад в, як використовують КТ для автоматизац управл ння
EVALUATION OF INTEGRALS OF FUNCTIONS OF COMPLEX VARIABLE BY USING THE RESIDUES IN COMPUTER MATHEMATICS SYSTEMS ОБЧИСЛЕННЯ НТЕГРАЛ В В Д ФУНКЦ Й КОМПЛЕКСНО ЗМ ННО ЗА ДОПОМОГОЮ ЗАЛИШК В В СИСТЕМАХ КОМП’ЮТЕРНО МАТЕМАТИКИ
Н.Д. Парфьонова,T.В. Клочко
Information Technologies and Learning Tools , 2010,
Abstract: The article describes the methodology of teaching one of the major topics of the course of complex analysis using the system Maple. It also demonstrates how the use of computer mathematics systems facilitates the evaluation of students by the teacher during organization of independent work. В статт наведено методику викладання мабуть одн з найважлив ших тем курсу комплексного анал зу з використанням системи Maple; демонстру ться, як використання систем комп’ютерно математики полегшу викладачев оц нювання роботи студент в та при орган зац х самост йно роботи.
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