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Search Results: 1 - 10 of 534826 matches for " T A Ogunlesi "
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Sever, prolonged neonatal hyperbilirubinaemia and recurrent hypoglycaemia: can this be Galactosaemia?
T A Ogunlesi, B O Ogunfowora, S A Sotimehin
Nigerian Journal of Paediatrics , 2005,
Socio-clinical issues in cerebral palsy in Sagamu, Nigeria
T Ogunlesi, M Ogundeyi, O Ogunfowora, A Olowu
South African Journal of Child Health , 2008,
Abstract: Background. Cerebral palsy (CP) is a common neurological disorder of childhood with significant implications. Objective. To determine the socio-clinical characteristics of children with CP at a paediatric neurology clinic in Sagamu, Nigeria. Methods. Hospital records of 92 children attending the clinic between 2000 and 2006 were reviewed. Demographic data were extracted and a validated socio-economic classification of parents was used. Results. The majority of babies had been delivered by primary health workers and traditional birth attendants. The prevalence of CP at the paediatric neurology clinic was 50.3%. Most subjects were aged 1 - 3 years (77.2%), were malnourished (80.4%) and belonged to the lower socio-economic groups (70.6%). The clinical types of CP were spastic (80.4%), hypotonic (12.0%), extrapyramidal (4.3%) and mixed (3.3%). Quadriplegia was the commonest type of spastic CP (66.2%). Asphyxia (57.6%), kernicterus (36.9%) and CNS infections (21.7%) were the leading identified causes. Co-morbidities such as seizures, microcephaly and speech and auditory deficits were present in 90.2% of the subjects. Seizures and microcephaly were commoner among CP cases associated with asphyxia than those associated with kernicterus (p=0.026 and p=0.005, respectively). Limitations. The rarity of prenatal causes of CP in this study may reflect our inability to investigate high-risk pregnancies adequately, particularly for intra-uterine infections. This also emphasises the inability of retrospective studies to adequately identify risk factors. Conclusion. Most patients with CP in this study were of low socio-economic status and had had perinatal problems. Improved perinatal care may reduce the burden of CP. Continuing training of health workers and traditional birth attendants is essential. It is hoped that this study will stimulate well-designed prospective studies.
Iatrogenic burns injury complicating neonatal resuscitation
T A Ogunlesi, S B Oseni, J A Okeniyi, J A Owa
West African Journal of Medicine , 2006,
Abstract: A case of iatrogenic thermal injury in a newborn infant during resuscitation for perinatal asphyxia at a secondary health facility is described. The injury, with surface area coverage of about 4%, involved the lower limbs. This report highlights the poor newborn resuscitation skills of traditional medical practice. Un cas d'une blessure therminale iatrogénique chez un bébé nouveau né au cours d'une réanimation pour l'asphyxie périnatale dans une centre sanitaire est l'objet de cette étude. La blessure dans les membres inférieurs a une surface d'environ 4%. Cette communication souligne la mauvaise méthode traditionnelle de la réanimation chez des nouveau nés.
The impact of the baby freindly hospital initiative on breastfeeding prectices in Ilesa
T A Ogunlesi, I O Dedeke, J A Okeniyi, G A Oyedeji
Nigerian Journal of Paediatrics , 2005,
Dermatoses in the Nigerian Newborn
O.A. Oyedeji,V.I. Joel-Medewase,T.A. Ogunlesi,G.A. Oyedeji
Research Journal of Medical Sciences , 2012,
Abstract: Dermatoses are common findings in newborns and their pattern varies from one geographical location to another. One hundred and thirty one babies aged between 1 and 7 days delivered at the post natal ward of the State Hospital, Osogbo South Western Nigeria over a 3 month time period were studied. The 131 babies consisted of 66 boys and 65 girls, thus giving a male to female ratio of 1:1. One hundred and twenty six babies (96.2%) had dermatoses, while 5 (3.8%) did not. Mongolian spots, miliaria, salmon patch, erythema toxicum, nevus, milia, cafe au lait spots and sebaceous hyperplasia were seen in 87(30.6%), 70(24.6%), 54(19.0%), 38(13.4%), 14 (4.9%), 13(4.6%),5(1.8%) and 3 (1.1%), respectively. Milia and sebaceous hyperplasia had a female predilection while the remaining dermatoses were more common in the male sex. Dermatoses were located on the buttocks, face, fore heads, napes, lower limbs, chest, eyelids, noses, upper limbs, necks, abdomen, backs and ears in 81(24.7%), 70(21.3%), 58(17.7), 38(11.6%), 15(4.6%),14(4.3%), 12(3.7%), 9(2.7%),9(2.7%), 7(2.1%), 7(2.1%), 7(2.1%) and 1(0.3%) cases, respectively. Of the 126 mothers whose babies had rashes, 28 (22.2%) were able to detect heat rashes in their babies prior to being examined. Most of the dermatoses recorded were benign. The cafe au lait spots on one of the 131 babies was a pointer to the diagnosis of neurofibromatosis. It is concluded that benign dermatoses of the newborn is common among the Nigerian newborn. The health care giver thus needs to be conversant with the dermatoses in his environment in other to manage them properly.
Neonatal Resuscitation: Knowledge And Practice Of Nurses In Western Nigeria
T Ogunlesi, O Dedeke, FA Adekanmbi,, BM Fetuga, AJ Okeniyi
South African Journal of Child Health , 2008,
Abstract: Background. Appropriate resuscitation techniques are crucial to the survival of newborn infants. Objective. To assess knowledge of nurses in western Nigeria about neonatal resuscitation. Method. A cross-sectional survey of the nurses attached to secondary health facilities in western Nigeria was done using a closed-ended questionnaire that tested evaluation and appropriate action aspects of neonatal resuscitation. Results. One hundred and seventy-nine nurses were interviewed. Of these, 72.6% had worked in the labour room and the special care baby unit within the last 5 years while only 14.0% had attended neonatal resuscitation training course within the last 5 years. Similarly, 31.8%, 53.1%, 58.1% and 35.2% had access to radiant warmers, ambu-bags, suction machine and oxygen delivery units, respectively. The knowledge of the respondents was better for evaluation than for appropriate action (95.5% v. 49.7%). Conclusion. The knowledge of the respondents about appropriate actions to be taken during neonatal resuscitation was poor. Frequent and intensive courses on neonatal resuscitation are highly desired. South African Journal of Child Health Vol. 2 (1) 2008: pp. 23-25
An Assessment of the Antimicrobial Properties of Extracts of Various Polarities from Chasmanthera dependens, Emilia coccinea and Cuscuta australis, Herbal Medications for Eye Diseases
W. Okiei,M. Ogunlesi,M.A. Ademoye
Journal of Applied Sciences , 2009,
Abstract: An assessment of the antimicrobial properties of extracts from the stem of Chasmantera dependens, the leaves of Emilia coccinea and the whole plant of Cuscuta australis plants which are used in the management of eye diseases in Nigeria is presented. The 50% methanol extracts were extracted sequentially with hexane, ethyl acetate and butanol to give fractions of various polarities which were tested for antimicrobial properties against various microorganisms including fungal yeast, Gram-positive and Gram-negative bacteria, namely Candida albicans, Bacillus subtillis, Citrobacter sp., Enterococcus faecalis, Escherichia coli, Escherichia coli ATCC 25922, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Salmonella sp., Salmonella typhimurium, Serratia marcescens, Shigella flexnerii, Staphylococcus albus, Staphylococcus aureus and Staphylococcus aureus ATCC 2593. The hexane fractions of all the plants were not found to possess antimicrobial activity on any of the microorganisms tested. The ethyl acetate fractions of C. dependens and E. coccinea were found to possess significant antimicrobial activity against several of the microorganisms while that of C. australis was active against only three of the microorganisms. The butanol fraction of E. coccinea showed significant antimicrobial activity against several of the microorganisms while those of C. dependens and C. australis were respectively active against only two and three of the microorganisms. The results support the use of E. coccinea as a potent anti-diarrhoeal agent and the uses of the plants as antimicrobials in herbal medicine.
Managing Neonatal Jaundice at the General Practice and Primary Health Care Level: An Overview
TA Ogunlesi
Nigerian Journal of Paediatrics , 2004,
Abstract: Neonatal Jaundice (NNJ) is one of the commonest causes of neonatal morbidity and mortality in the developing world. The physiological form of NNJ occurs in about two thirds of newborns. In addition to this however, are the various pathological forms which apart from being potentially fatal if not well managed, are often very difficult to differentiate from the benign physiological form, except with detailed laboratory investigations. Although the pathological forms of NNJ are ordinarily beyond the facilities usually available to General Practitioners (GPs) in developing countries, it is important that these GPs and the health workers at the primary health care level be well informed about NNJ since they are usually the first set of practitioners to receive babies with this illness. For better case management and reduction of mortality in NNJ, GPs should be able to sort babies with NNJ and manage them according to the severity of the illness. Mothers should be educated against harmful traditional practices which may provoke severe NNJ like the home use of naphthalene-containing balls. Home treatment of NNJ with the various local remedies should also be discouraged since these may not be helpful and may inadvertently cause them to seek medical advice late, with the attendant grave consequences. Nigerian Journal of Paediatrics Vol.31(2) 2004: 33-38
Diagnosis and treatment of bacterial meningitis in the newborn
TA Ogunlesi
Nigerian Journal of Paediatrics , 2013,
Abstract: Background: Bacterial meningitis in the newborn is globally renowned for high mortality. The associated morbidities also include audiologic, motor, visual and mental deficits. Objective: To highlight the peculiarities in the current diagnostic and management strategies in newborn meningitis. Methods: Relevant literature on the subject published only in English language or translated to English language was searched manually and electronically. The Medline, PUBMED and HINARI were searched for the period between 1966 and 2012. The following key words were used during the search: newborn/neonatal , bacter ial / pyogenic meningitis, central nervous system infections, antibiotics, dexamethasone and fluid restriction. Results: The pattern of bacterial aetiology and mortality differ between the developed and developing world. The usefulness of bacteriologic culture in the diagnosis of meningitis can be improved with serologic method like polymerase chain reaction. Widespread resistance of pathogens may be threatening the use of penicillins and gentamicin for empirical treatment of newborn meningitis. No sufficient evidence presently supports the current practices of fluid restriction, prolonged duration of antibiotic treatment and non-use of adjuvant steroid therapies in the newborn. Conclusion: Efforts to reduce the incidence of newborn meningitis cannot be separated from the prevention of newborn sepsis generally. In addition, more controlled trials are required in the developing world with respect to the various aspects of management of newborn meningitis, particularly fluid management and the use of adjuvant steroids.
Point-of-admission hypothermia among high-risk Nigerian newborns
Tinuade A Ogunlesi, Olusoga B Ogunfowora, Folashade A Adekanmbi, Bolanle M Fetuga, Durotoye M Olanrewaju
BMC Pediatrics , 2008, DOI: 10.1186/1471-2431-8-40
Abstract: To determine the incidence and outcome of point-of-admission hypothermia among hospitalized babies.The axillary temperatures of consecutive admissions into a Nigerian Newborn Unit were recorded. Temperature <36.5°C defined hypothermia. The biodata and outcome of these babies were studied.Of 150 babies aged 0 to 648 hours, 93 had hypothermia with an incidence of 62%. Mild and moderate hypothermia accounted for 47.3% and 52.7% respectively. The incidence of hypothermia was highest (72.4%) among babies aged less than 24 hours. It was also higher among out-born babies compared to in-born babies (64.4% vs 58.3%). Preterm babies had significantly higher incidence of hypothermia (82.5%) compared with 54.5% of term babies (RR = 1.51; CI = 1.21 – 1.89). The incidence of hypothermia was also highest (93.3%) among very-low-birth-weight babies.The Case-Fatality-Rate was significantly higher among hypothermic babies (37.6% vs 16.7%; RR = 2.26, CI = 1.14 – 4.48) and among out-born hypothermic babies (50% vs 17.1%; RR = 0.34, CI = 0.16 – 0.74). CFR was highest among hypothermic babies with severe respiratory distress, sepsis, preterm birth and asphyxia.The high incidence and poor outcome of hypothermia among high-risk babies is important. The use of the 'warm chain' and skin-to-skin contact between mother and her infant into routine delivery services in health facilities and at home may be useful.Neonatal hypothermia, defined by the World Health Organization (WHO) as axillary temperature less than 36.5°C, [1] is a major contributor to neonatal illnesses and deaths both in the developed and developing parts of the world. [2-5]The body temperature of a newborn infant tends to fall progressively after birth as part of the transition form the intra-uterine to extra-uterine environment [1] particularly among babies who are preterm, low birth weight or sick infants. [6] In most parts of the developing world, including Nigeria, where these groups of babies are commonly encountered in cli
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