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Search Results: 1 - 10 of 225214 matches for " Sylvia; Giadrosich R "
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Efecto de dosis altas de budesonida y función suprarrenal de ni os asmáticos severos High doses of inhaled budesonide and adrenal function in children with severe asthma
Aída Milinarsky T,Sylvia Fischer G,Vinka Giadrosich R,Viviana Lezana S
Revista médica de Chile , 2006,
Abstract: Background: The use of inhaled steroids is common in the treatment of bronchial asthma in children. Aim: To assess adrenocortical function in children with severe asthma receiving inhaled budesonide for six or more months. Material and methods: Children with severe asthma that required 800 μg/day or more of inhaled budesonide and that did not required systemic steroids for more than six days in the last four months to control their disease, were studied. Serum cortisol was measured one hour after administration of 0.25 mg of ACTH (Cosyntropin ) intravenously. The test was considered normal if post stimulation serum cortisol was over 18 μg/ml. Results: Twenty children (aged 5 to 14 years, 15 males), were studied. The stimulation test was normal in 17 children. Conclusions: Alterations in adrenal function are present in a small proportion of asthmatic children who require 800 μg/day of inhaled budesonide
Densidad mineral ósea en escolares nacidos prematuros Bone mineral density in school age infants born preterm
Aída Milinarsky T,Sylvia Fischer G,Vinka Giadrosich R,María Isabel Hernández C
Revista médica de Chile , 2003,
Abstract: The age at which children born preterm normalize their bone mineral density, is not well known. Aim: To study if children born preterm have normalized their bone mineral density at age 5 to 7 years. Patients and methods: Twenty six infants born preterm (14 male), were studied at age 5 to 7 years. Birth weight, present weight and height, bone age, calcium and phosphate intake at the first year of life and at the current age were assessed. Bone mineral density was measured by single photon X ray absorptiometry in the dominant forearm. A blood sample was obtained to measure insulin growth factor 1 (IGF-1). As a control group, 105 healthy age-paired infants born at term, were studied. Results: Bone mineral density was significantly lower in infants born preterm than in their term counterparts (0.273±0.01 g/cm2 and 0.302±0.01 g/cm2 respectively, p <0.001). There was a positive correlation between bone mineral density and IGF-1 (r=0.49, p=0.01). No correlation with the other measured parameters was observed. Conclusions: Infants that were born preterm have a lower bone mineral density at 5 to 7 years of age than their term controls. Bone mineral density correlates with IGF-1 (Rev Méd Chile 2003; 131: 1289-94).
Efecto de dosis altas de budesonida y función suprarrenal de ni?os asmáticos severos
Milinarsky T,Aída; Fischer G,Sylvia; Giadrosich R,Vinka; Lezana S,Viviana; Torres C,María Teresa;
Revista médica de Chile , 2006, DOI: 10.4067/S0034-98872006000100008
Abstract: background: the use of inhaled steroids is common in the treatment of bronchial asthma in children. aim: to assess adrenocortical function in children with severe asthma receiving inhaled budesonide for six or more months. material and methods: children with severe asthma that required 800 μg/day or more of inhaled budesonide and that did not required systemic steroids for more than six days in the last four months to control their disease, were studied. serum cortisol was measured one hour after administration of 0.25 mg of acth (cosyntropin?) intravenously. the test was considered normal if post stimulation serum cortisol was over 18 μg/ml. results: twenty children (aged 5 to 14 years, 15 males), were studied. the stimulation test was normal in 17 children. conclusions: alterations in adrenal function are present in a small proportion of asthmatic children who require 800 μg/day of inhaled budesonide
Densidad mineral ósea en escolares nacidos prematuros
Milinarsky T,Aída; Fischer G,Sylvia; Giadrosich R,Vinka; Hernández C,María Isabel; Torres C.,María Teresa;
Revista médica de Chile , 2003, DOI: 10.4067/S0034-98872003001100009
Abstract: the age at which children born preterm normalize their bone mineral density, is not well known. aim: to study if children born preterm have normalized their bone mineral density at age 5 to 7 years. patients and methods: twenty six infants born preterm (14 male), were studied at age 5 to 7 years. birth weight, present weight and height, bone age, calcium and phosphate intake at the first year of life and at the current age were assessed. bone mineral density was measured by single photon x ray absorptiometry in the dominant forearm. a blood sample was obtained to measure insulin growth factor 1 (igf-1). as a control group, 105 healthy age-paired infants born at term, were studied. results: bone mineral density was significantly lower in infants born preterm than in their term counterparts (0.273±0.01 g/cm2 and 0.302±0.01 g/cm2 respectively, p <0.001). there was a positive correlation between bone mineral density and igf-1 (r=0.49, p=0.01). no correlation with the other measured parameters was observed. conclusions: infants that were born preterm have a lower bone mineral density at 5 to 7 years of age than their term controls. bone mineral density correlates with igf-1 (rev méd chile 2003; 131: 1289-94).
Densitometría ósea en ni?os leucémicos al completar el primer mes de quimioterapia
Fischer G,Sylvia; Neira L,Laura; Ferreiro M,Myriam; Torres C,María Teresa; Giadrosich R,Vinka; Milinarsky T,Aída; Arriagada M,Marina; Arinoviche S,Roberto;
Revista médica de Chile , 2005, DOI: 10.4067/S0034-98872005000100009
Abstract: background: an important loss of bone mineral density, associated to pain and fractures, has been reported in children with acute lymphoblastic leukemia (all). aim: to measure bone mineral density among children with acute lymphoblastic leykemia (all) that completed the remission induction phase with chemotherapy, that lasts 30 days. patients and methods: children with all, admitted to the oncology unit of a general hospital were considered eligible for the study. body composition and bone mineral density were measured by dual energy x ray absorptiometry (dexa). each child with all was paired with a healthly control. results: fourteen children age 1 to 11 years, completed the study, spine and femoral bone mineral desities were significantly lower than in their matched controls. no differences in total body bone mineral density or content were observed. children with all had a lower fat free mass and a higher fat mass than their matched controls. there was a significant correlation between fat free mass and bone mineral content. conclusions: after one month of chemotherapy, children with all had a lower bone mineral density in the spine and femur and a lower fat free mass (rev méd chile 2005; 133: 71-76)
Normalización de la densidad mineral ósea en ni os nacidos prematuros en Vi a del Mar, Chile Normalization of bone mineral density in premature-born children from Vi a del Mar, Chile
Aída Milinarsky,Sylvia Fischer,Vinka Giadrosich,María Teresa Torres
Revista médica de Chile , 2007,
Abstract: Background: In a previous study we reported that healthy children born at 34 or fewer gestational weeks, with adequate weight for gestational age, had not completed their bone catch-up at mean age of 6.3 years. Aim: This is a follow up report, performed on the same population one year later to determine at which age premature - born children achieve their bone mineral density (BMD) catch-up, compared to term-born controls. Material and methods: Fifteen children mean age 7years 3 months, born at 25 to 34 weeks of gestation, with a birth weight of 740 to 2.200 g were studied Radius, lumbar spine and femoral neck bone mineral density, whole body bone mineral content and body composition were assessed by DEXA. Results: Height, body mass index, peripheral BMD, axial BMD, fat and lean body mass in these children were not different from term born controls. Conclusions: Premature born children with adequate weight for gestational age, achieved peripheral and axial bone mineral density catch-up at the age of 7 to 8 years
Normalización de la densidad mineral ósea en ni?os nacidos prematuros en Vi?a del Mar, Chile
Milinarsky,Aída; Fischer,Sylvia; Giadrosich,Vinka; Torres,María Teresa; Arriagada,Marina; Arinoviche,Roberto; Casanova,Dunny;
Revista médica de Chile , 2007, DOI: 10.4067/S0034-98872007001200007
Abstract: background: in a previous study we reported that healthy children born at 34 or fewer gestational weeks, with adequate weight for gestational age, had not completed their bone catch-up at mean age of 6.3 years. aim: this is a follow up report, performed on the same population one year later to determine at which age premature - born children achieve their bone mineral density (bmd) catch-up, compared to term-born controls. material and methods: fifteen children mean age 7years 3 months, born at 25 to 34 weeks of gestation, with a birth weight of 740 to 2.200 g were studied radius, lumbar spine and femoral neck bone mineral density, whole body bone mineral content and body composition were assessed by dexa. results: height, body mass index, peripheral bmd, axial bmd, fat and lean body mass in these children were not different from term born controls. conclusions: premature born children with adequate weight for gestational age, achieved peripheral and axial bone mineral density catch-up at the age of 7 to 8 years
Chemical Basis for the Phytotoxicity of Indoles in Relation to the Allelopathy of Cereals  [PDF]
Héctor R. Bravo, Sylvia Copaja
Agricultural Sciences (AS) , 2018, DOI: 10.4236/as.2018.911101
Abstract: Phytotoxic activity of an indole series substituted with electron-acceptor and electron-donor groups in the aromatic ring was determined. They are potential decomposition products, of natural indole alkaloids in cereals plants with allelopathic properties. Phytotoxic selectivity was evaluated from antialgal activity against the microalga Chlorella vulgaris, seed germination seeds and biomass weight of seedling of barley, rye, wheat, oat and maize species and the weed Lolium rigidum. Lipophilia character of the compounds was determined by RP-HPLC method. Both, the electronic character of the substituents, evaluated from σp parameter, and the lipophilia character of the molecules measured from logPHPLC parameter, are involved in the phytotoxic activity. The three bio indicators has shown that the compounds with the higher electron-acceptor groups showed the higher level of phytotoxicity and the molecules with electron-donor groups showed the lowest activity, although, in some cases, this behavior is modified by the lipophilic properties of the molecules. These results are rationalized in terms of polarization of N-H bond of heterocyclic ring. Compounds with the higher logPHPLC values showed the higher phytotoxic activity. Further evidence on the role of lipophilicity was obtained from linear regression between the average inhibitions percentages of biomass and logPHPLC values. The activity increased linearly by increasing the lipophilic character of the compounds. Therefore, quantitative effects in the phytotoxic activity of the electronic properties of the substituents in the aromatic ring and lipophilic character of the indoles can be inferred from σp and logPHPLC parameters, respectively. The results strongly suggest that the potential decomposition products of the natural indole alkaloids from cereals or other natural sources may be in connection with the allelopathic phenomenon of plants when are released into the soil.
Tiroiditis aguda supurada en un paciente pediátrico: Report of a pediatric case
Giadrosich R,Vinka; Hernández C,M Isabel; Izquierdo Q,Claudia; Zamora K,Beatriz;
Revista médica de Chile , 2004, DOI: 10.4067/S0034-98872004000200012
Abstract: acute suppurative thyroiditis (ast) is an uncommon condition because thyroid gland is remarkably resistant to infections. in children, anatomic defects such as a left pyriform sinus fistula or a thyroglossal duct remnant predispose to this infection. once the diagnosis is confirmed by ultrasound or computed tomography, antimicrobial therapy based on the culture and gram staining must be started. after two or three weeks of treatment, predisposing anatomic defects must be sought cautiously. we report a 13 years old girl presenting with cervical pain and fever. a cervical ultrasound showed an enlarged thyroid lobule with hypoecogenic zones that suggested a supurative collection. cefotaxime and cloxacillin were started. a needle aspiration of the collection obtained a purulent material. the culture of this material yielded a streptococcus pneumoniae. the clinical condition of the patient improved and she was discharged in good conditions. two months later a contrast esophagus x ray did not show predisposing anatomic defects. (rev méd chile 2004; 132: 219-22)
Tiroiditis aguda supurada en un paciente pediátrico: Report of a pediatric case Acute suppurative thyroiditis
Vinka Giadrosich R,M Isabel Hernández C,Claudia Izquierdo Q,Beatriz Zamora K
Revista médica de Chile , 2004,
Abstract: Acute suppurative thyroiditis (AST) is an uncommon condition because thyroid gland is remarkably resistant to infections. In children, anatomic defects such as a left pyriform sinus fistula or a thyroglossal duct remnant predispose to this infection. Once the diagnosis is confirmed by ultrasound or computed tomography, antimicrobial therapy based on the culture and Gram staining must be started. After two or three weeks of treatment, predisposing anatomic defects must be sought cautiously. We report a 13 years old girl presenting with cervical pain and fever. A cervical ultrasound showed an enlarged thyroid lobule with hypoecogenic zones that suggested a supurative collection. Cefotaxime and cloxacillin were started. A needle aspiration of the collection obtained a purulent material. The culture of this material yielded a Streptococcus Pneumoniae. The clinical condition of the patient improved and she was discharged in good conditions. Two months later a contrast esophagus X ray did not show predisposing anatomic defects. (Rev Méd Chile 2004; 132: 219-22)
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