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Suzanne Keene
Papers from the Institute of Archaeology , 2007, DOI: 10.5334/pia.285
Collections in the English National Museums: The Numbers
Suzanne Keene
Papers from the Institute of Archaeology , 2007, DOI: 10.5334/pia.291
Abstract: The DCMS (Department of Culture Media and Sport) commissioned a report in 2002, delivered in 2003, from consultants PKF, on the storage of the collections of the national museums. Their report and a paper based on it, compiled by the DCMS in 2004, was obtained under the Freedom of Information Act. The intention in this article is rather to investigate the usefulness or lack of these statistics and to understand what issues should be taken account of in any future investigation. Although most of the data are problematic to interpret due to the questions asked in data collection, some useful statitics are provided including on the general quantification of collections in the English national museums. The figures illustrate the magnitude of and variation between collections, and confirm observations from real life on the corresponding variation in storage requirements.
Communicating city histories
Suzanne Keene
Archaeology International , 2003, DOI: 10.5334/ai.0715
Abstract: New developments in electronic communications have the capacity to transform the ways in which people gain access to archaeological and historical information. Several projects are already under way, which aim to disseminate urban history to the public in London and other European cities.
Can museums survive the postmodern?
Suzanne Keene
Archaeology International , 2005, DOI: 10.5334/ai.0910
Abstract: Although archaeologists regard museums as vital repositories of important research materials, museum professionals take a broader view of their role in not only preserving natural and cultural heritage but also of how they could or should be presented, or interpreted, to the public. In this personal view, issues of what museums should be, or seek to be, in a postmodern world are explored.
A cross sectional study of assessed need and multiple service use among a self harm population: informing the development of inter-agency integrated care
J. Keene
International Journal of Integrated Care , 2005,
Abstract: Purpose: To examine assessed need and wider health and social care service contact for a total Deliberate Self Harm (DSH) population in the UK. Methods: The study first recorded assessed needs and referrals for this population, then used a new method of identifying and describing all other agency contacts for this population by combining the total anonymised DSH population data with total mental health, health and social care agency populations for one geographical area. Results: For a DSH unit population of 427, half (53%) were assessed with mental health and 18% with drug or alcohol problems; two thirds were referred to appropriate services. Wider service contact for a total DSH population (n=2,205 over three years) confirmed that 53% had contacted mental health (compared to 2.9% of the geographical area population (n=646,239) and 7.4% of the total hospital Emergency population (n=91,911). The DSH population was three times more likely to contact social care agencies (21.1%: 7.2%) and ten times more likely to attend drug (7.3%: 0.7%) and alcohol agencies (8.8%: 0.8%) Conclusions: This new method described the wider service use of one vulnerable shared care population, it is suggested that the method could be used to inform the development of integrated care initiatives in different areas.
Cinema and Prosthetic Memory: The Case of the Korean War
Judith Keene
PORTAL : Journal of Multidisciplinary International Studies , 2010,
Abstract: This paper assesses the explanatory possibilities of the concept of prosthetic memory, with cinema as the enabler of popular understanding, when applied to the Korean War. The essay examines why it was that the conflict in Korea for many decades occupied a memory void and whether the explanations that have been offered for other similar “forgotten “wars are useful in relation to Korea. The analysis sugggests that cinema may be important in the formation of popular understanding but that there are serious analytical drawbacks in assuming that cinema can provide a window into popular mentalities.
Sensitivity Evaluation of Two Human Breast Cancer Cell Lines to Tamoxifen through Apoptosis Induction  [PDF]
Spencer Keene, Charles Azuelos, Shyamal K. Majumdar
Open Journal of Apoptosis (OJApo) , 2014, DOI: 10.4236/ojapo.2014.34008
Abstract: Tamoxifen citrate (TAM) has been used to treat breast cancer in women for many years. The com-parative effects of TAM in inducing apoptosis were evaluated in estrogen receptor-positive (ER- positive MCF-7) and estrogen receptor-negative (ER-negative MDA-MB-231) human breast cancer cell lines in vitro in order to determine if these two cell lines differ in their sensitivity to TAM. Mi-tochondrial membrane permeability potential disruption was assessed in both cell lines by a lip-ophilic cationic dye (DePsipher assay, Trevigen, Inc.) utilizing fluorescence microscopy. Using this specific fluorochrome, we were able to associate mitochondrial membrane disruption to early, mid-, and late apoptotic cells. TAM induced cell death via apoptosis in both ER-positive and ER- negative cells, however, apoptosis induction was more pronounced in ER-positive MCF-7 compared to ER-negative MDA-MB-231 breast cancer cells. These findings may have some therapeutic use in the treatment of estrogen dependent and estrogen independent breast cancer.
Market Segmentation of 92 Arab Banks  [PDF]
Suzanne Charbaji
Open Journal of Accounting (OJAcct) , 2017, DOI: 10.4236/ojacct.2017.63006
Abstract: The aim of this paper is to conduct market segmentation of Arab banks and suggest a model to classify them into cohesive segments on the basis of their financial ratios as a guideline for future consolidation. Twelve financial ratios taken from Bankscope Database have been retrieved for 92 Arab banks for the year 2015. In view of the sensitivity of multivariate analysis to the normality assumption, it was decided to use the common log transformation. Factor analysis is used as a data reduction technique to find twelve financial ratios. Cluster analysis is then used to separate the 92 Arab banks into five different performance groups (segments). Multi-discriminant statistical analysis is used to answer the question: can a combination of financial ratios be used to predict bank’s group membership? Findings of the study show that multidiscriminant analysis reveals that coverage ratio, profitability and efficiency separate the groups more widely than other financial ratios. The classification matrix shows that 98.9% of original banks are correctly classified. What’s more, to go after a more efficient risk policy, this paper recommends merging big banks with small Arab banks that are less profitable, less efficient, and in weaker condition than their non-acquired peers in addition to merging huge banks operating in different Arab countries. Results of this study should provide insight for future researchers. Also, this piece of research bridges the gap between financial ratio analysis and multivariate statistical analysis for Arab banks.
The global dynamics of RNA stability orchestrates responses to cellular activation
Jack D Keene
BMC Biology , 2010, DOI: 10.1186/1741-7007-8-95
Abstract: See research article http://www.biomedcentral.com/1471-2164/11/259 webciteA commonly overlooked fact regarding microarray-derived as well as high-throughput sequencing data is that the accumulated (so called steady-state) levels of mRNAs depend on rates of RNA transcription and degradation at the time of RNA extraction (Figure 1). While this fact has become increasingly evident among researchers who are interested in the underlying mechanisms of gene expression, those focused on transcription per se often interpret their data while assuming that changes in mRNA levels are due to the activation or repression of transcription alone.It is therefore useful to have this assumption further challenged by Agami and co-workers (Elkon et al.) [1], who examined on a global scale the role of mRNA stability in shaping the kinetics of gene responses. RNA decay is now a rapidly growing field, but only recently have investigators begun to consider that global changes in mRNA stability can indicate systematic coordination across functionally related transcripts as governed by trans-acting factors [2]. Indeed, several studies over the past 10 years have found that specific groups of transcripts can coordinately change their stability in response to cellular signals - and that this is a property of most organisms. This tenet of the posttranscriptional RNA operon/regulon model of coordinated gene expression is best illustrated in studies of the immune system of vertebrates and in model organisms such as yeast and trypanosomes (reviewed in [3-7]).Elkon et al. [1] examined published gene-expression profiles that had been generated by stimulation of T cells with interleukin 2 (IL-2), and evaluated these data in relation to other published data comprising a global atlas of mRNA stability [8]. The mRNAs induced in response to IL2 grouped as three clusters, the early, intermediate and late-responding gene groups, and there was a striking correlation between the response time post IL2 stimula
The Cardiothoracic Anaesthesia Society of South Africa (CASSA) consensus paper for accreditation of anaesthetists in South Africa in perioperative echocardiography
A Keene, A Myburgh
Southern African Journal of Anaesthesia and Analgesia , 2012,
Abstract: There is a need to develop an accreditation process for South African physicians who practise perioperative echocardiography. International level accreditation will bring legitimacy to the process of training practitioners in perioperative echocardiography and ensure standards of practice. Accreditation will be developed as a two-year process during which candidates with a College Fellowship or MMed degree may register with a supervisor and submit a portfolio of 120 comprehensive echo reports and five complete digital studies for assessment. If these are judged to be of an adequate standard, the candidate will be eligible to sit an exam consisting of a multiple-choice question theory and echo video paper and an oral exam.
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