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Search Results: 1 - 10 of 15439 matches for " Sunyoung Ji "
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The Effect of D-( )-arabinose on Tyrosinase: An Integrated Study Using Computational Simulation and Inhibition Kinetics
Hong-Jian Liu,Sunyoung Ji,Yong-Qiang Fan,Li Yan
Enzyme Research , 2012, DOI: 10.1155/2012/731427
Abstract:
Mobile Node Authentication Protocol for Proxy Mobile.
Jungwook Song,,Sunyoung Han
International Journal of Computer Science & Applications , 2009,
Abstract:
Fixed Point Iterations of a Pair of Hemirelatively Nonexpansive Mappings
Hao Yan,Cho SunYoung
Fixed Point Theory and Applications , 2010,
Abstract: We introduce an iterative method for a pair of hemirelatively nonexpansive mappings. Strong convergence of the purposed iterative method is obtained in a Banach space.
Hamiltonian analysis of Linearized Extension of Ho?ava-Lifshitz gravity
Seoktae Koh,Sunyoung Shin
Physics , 2010, DOI: 10.1016/j.physletb.2010.12.066
Abstract: We investigate the Hamiltonian structure of linearized extended Ho\v{r}ava- Lifshitz gravity in a flat cosmological background following the Faddeev-Jackiw's Hamiltonian reduction formalism. The Hamiltonian structure of extended Ho\v{r}ava-Lifshitz gravity is similar to that of the projectable version of original Ho\v{r}ava-Lifshitz gravity, in which there is one primary constraint and so there are two physical degrees of freedom. We also find that extra scalar graviton mode in an inflationary background can be decoupled from the matter field in the infrared (IR) limit, but it is coupled to the matter field in a general cosmological background. But it is necessary to go beyond linear order in order to draw any conclusion of the strong coupling problem.
The Effect of D-(?)-arabinose on Tyrosinase: An Integrated Study Using Computational Simulation and Inhibition Kinetics
Hong-Jian Liu,Sunyoung Ji,Yong-Qiang Fan,Li Yan,Jun-Mo Yang,Hai-Meng Zhou,Jinhyuk Lee,Yu-Long Wang
Enzyme Research , 2012, DOI: 10.1155/2012/731427
Abstract: Tyrosinase is a ubiquitous enzyme with diverse physiologic roles related to pigment production. Tyrosinase inhibition has been well studied for cosmetic, medicinal, and agricultural purposes. We simulated the docking of tyrosinase and D-(?)-arabinose and found a binding energy of ?4.5?kcal/mol for theup-formof D-(?)-arabinose and ?4.4?kcal/mol for thedown-form of D-(?)-arabinose. The results of molecular dynamics simulation suggested that D-(?)-arabinose interacts mostly with HIS85, HIS259, and HIS263, which are believed to be in the active site. Our kinetic study showed that D-(?)-arabinose is a reversible, mixed-type inhibitor of tyrosinase ( -value? , ?M). Measurements of intrinsic fluorescence showed that D-(?)-arabinose induced obvious tertiary changes to tyrosinase (binding constant ?M?1, binding number ). This strategy of predicting tyrosinase inhibition based on specific interactions of aldehyde and hydroxyl groups with the enzyme may prove useful for screening potential tyrosinase inhibitors. 1. Introduction Tyrosinase (EC 1.14.18.1) is a ubiquitous enzyme with diverse physiologic roles related to pigment production. It plays a central role in melanin synthesis in skin [1, 2], the browning of vegetables [3, 4], wound healing [5], and cuticle formation in insects [6, 7]. Structurally, tyrosinase belongs to the type 3 copper protein family [8, 9], which consists of two copper ions individually coordinated with three histidine residues at the active site. Tyrosinases are directly involved in several reactions and carry out catalytic steps such as the hydroxylation of tyrosine to 3,4-dihydroxyphenylalanine (DOPA), the oxidation of DOPA to DOPA quinone, and the oxidation of 5,6-dihydroxyindole to 5,6-dihydroxuquinone [10, 11]. In addition to its catalytic features, tyrosinase is distinctive from other enzymes because it displays various inhibition patterns. Tyrosinase inhibition has been extensively studied for cosmetic, medicinal, and agricultural purposes [12]. The tyrosinase mechanism is complex, and this enzyme can catalyze multiple reactions. Despite several reported crystallographic structures of tyrosinase, the 3D structure and architecture of the active site are not well understood [22, 23]. Mechanistic studies must involve a variety of computational methods and kinetic analysis to derive the structure-function relationship between substrates and ligands. The inhibitory effect of compounds with sugar backbones on tyrosinase are of great interest [20, 24, 25]. D-(–)-arabinose, a potential tyrosinase inhibitor, is an aldopentose with one
Hybrid Projection Algorithms for Generalized Equilibrium Problems and Strictly Pseudocontractive Mappings
Kim JongKyu,Cho SunYoung,Qin Xiaolong
Journal of Inequalities and Applications , 2010,
Abstract: The purpose of this paper is to consider the problem of finding a common element in the solution set of equilibrium problems and in the fixed point set of a strictly pseudocontractive mapping. Strong convergence of the purposed hybrid projection algorithm is obtained in Hilbert spaces.
Convergence of Iterative Sequences for Generalized Equilibrium Problems Involving Inverse-Strongly Monotone Mappings
Kang ShinMin,Cho SunYoung,Liu Zeqing
Journal of Inequalities and Applications , 2010,
Abstract: The purpose of this paper is to consider the weak convergence of an iterative sequence for finding a common element in the set of solutions of generalized equilibrium problems, in the set of solutions of classical variational inequalities, and in the set of fixed points of nonexpansive mappings.
Moudafi's Viscosity Approximations with Demi-Continuous and Strong Pseudo-Contractions for Non-Expansive Semigroups
Wu Changqun,Cho SunYoung,Shang Meijuan
Journal of Inequalities and Applications , 2010,
Abstract: We consider viscosity approximation methods with demi-continuous strong pseudo-contractions for a non-expansive semigroup. Strong convergence theorems of the purposed iterative process are established in the framework of Hilbert spaces.
Convergence Theorems on Generalized Equilibrium Problems and Fixed Point Problems with Applications
Hao Yan,Cho SunYoung,Qin Xiaolong
Journal of Inequalities and Applications , 2010,
Abstract: The purpose of this work is to introduce an iterative method for finding a common element of a solution set of a generalized equilibrium problem, of a solution set solutions of a variational inequality problem and of a fixed point set of a strict pseudocontraction. Strong convergence theorems are established in the framework of Hilbert spaces.
Convergence of Iterative Sequences for Common Zero Points of a Family of -Accretive Mappings in Banach Spaces
Qing Yuan,Cho SunYoung,Qin Xiaolong
Fixed Point Theory and Applications , 2011,
Abstract: We introduce implicit and explicit viscosity iterative algorithms for a finite family of -accretive operators. Strong convergence theorems of the iterative algorithms are established in a reflexive Banach space which has a weakly continuous duality map.
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