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Search Results: 1 - 10 of 3358 matches for " Sunhee Cho "
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Logo-autobiography and its effectiveness on depressed Korean immigrant women: A replication study
Sunhee Cho,Kunsook S. Bernstein,Soyeon Cho,Soonhee Roh
Journal of Nursing Education and Practice , 2012, DOI: 10.5430/jnep.v3n6p51
Abstract: Objective: This study aimed to examine the longevity of Logo-Autobiography (LA)’s effects and to identify whether different providers and different types of LA intervention have diverse impact on the outcomes for Korean immigrant women with depression. Methods: A pre-experimental research was conducted with pre-, post-, and 4-week follow-up tests using the CES-D depressive symptoms and Purpose in Life scales. LA included a structured weekly session for 6 weeks in either individual or group setting, and autobiography writing with predesigned topics for each session. A total of 47 subjects participated in this study. Repeated measures of ANOVA were conducted to investigate if there were differences between the experimental and control groups. Results: All hypotheses were supported that the experimental group showed 1) significantly lower scores on depressive symptoms, 2) significantly higher scores on purpose in life, and 3) no differences of depressive symptoms and meaning of life scores between medication and non-medication groups, group vs. individual interventions, and among three different providers in the post-test and the 4-week follow-up test. Conclusions: LA may be considered as another alternative therapeutic intervention in treating Korean-American immigrant women who suffer from depression and lost meaning in life. Further studies are needed with a larger sample size using rigorous randomized designs to validate the effectiveness of the LA.
Exploration of New Electroacupuncture Needle Material
Sanghun Lee,Gwang-Ho Choi,Chang Hoon Lee,Yu Kyoung Kim,Saebhom Lee,Sungjin Cho,Sunhee Yeon,Sun-Mi Choi,Yeon-Hee Ryu
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/612545
Abstract: Background. Electro Acupuncture (EA) uses the acupuncture needle as an electrode to apply low-frequency stimulation. For its safe operation, it is essential to prevent any corrosion of the acupuncture needle. Objective. The aim of this study is to find an available material and determine the possibility of producing a standard EA needle that is biocompatible. Methods. Biocompatibility was tested by an MTT assay and cytotoxicity testing. Corrosion was observed with a scanning electron microscope (SEM) after 0.5 mA, 60 min stimulation. The straightness was measured using a gap length of 100 mm, and tensile testing was performed by imposing a maximum tensile load. Results. Phosphor bronze, Ni coated SS304, were deemed inappropriate materials because of mild-to-moderate cytotoxicity and corrosion. Ti-6Al-4V and SS316 showed no cytotoxicity or corrosion. Ti-6Al-4V has a 70 times higher cost and 2.5 times lower conductivity than SS316. The results of both straightness and tensile testing confirmed that SS316 can be manufactured as a standard product. Conclusion. As a result, we confirmed that SS316 can be used a new EA electrode material. We hope that a further study of the maximum capacity of low-frequency stimulation using an SS316 for safe operation.
Immunization with a Hemagglutinin-Derived Synthetic Peptide Formulated with a CpG-DNA-Liposome Complex Induced Protection against Lethal Influenza Virus Infection in Mice
Jae Won Rhee,Dongbum Kim,Byung Kwon Park,Sanghoon Kwon,Sunhee Cho,Ilseob Lee,Man-Seong Park,Jae-Nam Seo,Yong-Sun Kim,Hong Seok Choi,Younghee Lee,Hyung-Joo Kwon
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0048750
Abstract: Whole-virus vaccines, including inactivated or live-attenuated influenza vaccines, have been conventionally developed and supported as a prophylaxis. These currently available virus-based influenza vaccines are widely used in the clinic, but the vaccine production takes a long time and a huge number of embryonated chicken eggs. To overcome the imperfection of egg-based influenza vaccines, epitope-based peptide vaccines have been studied as an alternative approach. Here, we formulated an efficacious peptide vaccine without carriers using phosphodiester CpG-DNA and a special liposome complex. Potential epitope peptides predicted from the hemagglutinin (HA) protein of the H5N1 A/Viet Nam/1203/2004 strain (NCBI database, AAW80717) were used to immunize mice along with phosphodiester CpG-DNA co-encapsulated in a phosphatidyl-β-oleoyl-γ-palmitoyl ethanolamine (DOPE):cholesterol hemisuccinate (CHEMS) complex (Lipoplex(O)) without carriers. We identified a B cell epitope peptide (hH5N1 HA233 epitope, 14 amino acids) that can potently induce epitope-specific antibodies. Furthermore, immunization with a complex of the B cell epitope and Lipoplex(O) completely protects mice challenged with a lethal dose of recombinant H5N1 virus. These results suggest that our improved peptide vaccine technology can be promptly applied to vaccine development against pandemic influenza. Furthermore our results suggest that potent epitopes, which cannot be easily found using proteins or a virus as an antigen, can be screened when we use a complex of peptide epitopes and Lipoplex(O).
SPECT Imaging of Epilepsy: An Overview and Comparison with F-18 FDG PET
Sunhee Kim,James M. Mountz
International Journal of Molecular Imaging , 2011, DOI: 10.1155/2011/813028
Abstract: Epilepsy surgery is highly effective in treating refractory epilepsy, but requires accurate presurgical localization of the epileptogenic focus. Briefly, localization of the region of seizure onset traditionally dependents on seizure semiology, scalp EEG recordings and correlation with anatomical imaging modalities such as MRI. The introduction of noninvasive functional neuroimaging methods, including single-photon emission computed tomography (SPECT) and positron emission tomography (PET) has dramatically changed the method for presurgical epilepsy evaluation. These imaging modalities have become powerful tools for the investigation of brain function and are an essential part of the evaluation of epileptic patients. Of these methods, SPECT has the practical capacity to image blood flow functional changes that occur during seizures in the routine clinical setting. In this review we present the basic principles of epilepsy SPECT and PET imaging. We discuss the properties of the SPECT tracers to be used for this purpose and imaging acquisition protocols as well as the diagnostic performance of SPECT in addition to SPECT image analysis methods. This is followed by a discussion and comparison to F-18 FDG PET acquisition and imaging analysis methods. 1. Introduction Epilepsy surgery can be highly effective in treating refractory epilepsy if performed in properly selected patients with well-delineated ictal foci [1]. The greatest challenge is accurate localization, but only a small fraction of the patients whose epilepsy becomes refractory ultimately receive surgery. In the past, localization of the region of seizure onset was dependent upon scalp, cortical, and depth electroencephalography (EEG). However, scalp EEG has disadvantages such as dependency on cortical surface effects and low spatial resolution that can lead to mislocalization of epileptogenic foci. Both cortical and depth EEG have a limited spatial sampling area that is confined to regions accessible by electrode placement. Depth EEG can detect signals from deeper structures, but it is more invasive, which can lead to surgical complications [2]. The introduction of noninvasive neuroimaging methods, such as single-photon emission computed tomography (SPECT), positron emission tomography (PET), and magnetic resonance imaging (MRI), has dramatically changed presurgical epilepsy evaluation. These imaging methods have become powerful tools for the investigation of brain function and an essential part of the evaluation of epileptic patients. Of these methods, only SPECT has the practical capacity to
Posturographic Evaluation of Dizziness Complaining Patients under Suspicion to Develop Parkinson's Disease  [PDF]
Hyun Cho
Neuroscience & Medicine (NM) , 2011, DOI: 10.4236/nm.2011.21004
Abstract: Although the typical clinical signs of Parkinson disease (PD) are tremor, rigidity, bradykinesia, and postural instability, PD is preceded by a preclinical phase during which neuronal degeneration develops without typical symptoms. More general nonspecific symptoms including dizziness have also been described to predate the typical PD signs for several years. All subjects were selected among patients in the Willis Hospital (Pusan, South of Korea), with complaints of diz-ziness from September 2009 to September 2010 and the baseline neurological screening and clinical ENT examination, to which the results were within the normal range. At baseline, 113 participants underwent neurological screening and provided information on dizziness. Of those participants, 103 were enrolled including 63 subjects in the control group. We used posturography. It allows quantitative assessment of vestibular-spinal component of body balance. The parame-ter of average speed of pressure center displacement to the lateral plan (VMX) and antero-posterior plan (VMY), which presented statistically significant differences between the groups except VMX with closed eyes. (p = 0.008 and p = 0.012, with closed eyes). With open eyes, only VMY showed significant difference between the groups (p = 0.010). In this study, the patients with dizziness and subjective complaints related to typical clinical signs of PD complaints presented higher instability in the orthostatic position than the control group of patients with dizziness and without such complaint. It could suggest that dizziness may be one symptom of preclinical PD and progress to overt postural instability. It is believed that a stepwise approach with a simple and inexpensive initial screening test of preclinical PD is required.
To Open or Not to Open: Korean Rice Market  [PDF]
Youngjeen Cho
Beijing Law Review (BLR) , 2014, DOI: 10.4236/blr.2014.54023
Abstract: Although the “tariff only” principle was adopted in the Uruguay Round (UR) negotiations on agricultural products, Korea was able to apply special treatment to its rice and postpone tariffication of rice imports. After two decades of delay, the Korean government officially announced its decision to open its rice market beginning in 2015. This paper examines whether it would be legally possible for the Korean government to postpone the tariffication of rice imports beyond 2014. In order to address the question, this paper outlines the status of Korean rice in the WTO for the last twenty years. Then, it analyzes the arguments of those who are against tarifficating rice and of those who are in support of it. Based on the analysis, it concludes that Korea cannot postpone tariffication under Annex 5 of the Agreement on Agriculture. While it may request for a waiver under Article IX of the WTO Agreement, a careful and thorough examination is required to decide whether to postpone the tariffication beyond 2014.
Revisiting WTO Fisheries Subsidies Negotiations  [PDF]
Youngjeen Cho
Beijing Law Review (BLR) , 2015, DOI: 10.4236/blr.2015.61002
Abstract: Fisheries subsidies negotiation was added to the negotiation agenda of the DDA largely by the concern for the depletion of fishery stocks. Some members, in particular, the Friends of Fish group countries, claimed that over-fishing and overcapacity caused by various fisheries subsidies program have resulted in the depletion of fishery stocks. Therefore, they argued that new disciplines should be introduced to address the situation. In 2007, after more than five years of negotiations, the chairman of the Rules Negotiations Group circulated a consolidated text. However, the negotiations have hardly made progress since then. This paper examines whether the Rule Negotiating Group chair’s text is legally and practically appropriate to serve as a basis for the fisheries subsidies negotiations. In order to address the question, this paper presents the brief history of fisheries subsidies negotiations at the WTO. Then, it analyzes critical issues of the Rule Negotiating Group chair’s text. It also explores the consolidated text of the TPP negotiations. Based on the analysis, it concludes that the basic concept and the principle of the chair’s text are inconsistent with those of the ASCM, and that the structure of the text does not conform those of the ASCM and other WTO agreements. Likewise, the TPP text bears similar problems. Therefore, it is highly questionable whether WTO members and TPP parties can actually achieve the goal to conserve fishery resources. WTO members as well as TPP parties should try to address these problems, so that they can make real progress in negotiations.
Targeting Phosphodiesterase 4 to Block the Link between Acute Exacerbation of Chronic Obstructive Pulmonary Disease and the Metabolic Complications  [PDF]
Eric Cho
Journal of Biosciences and Medicines (JBM) , 2015, DOI: 10.4236/jbm.2015.311007
Abstract: The metabolic disorders such as obesity and diabetes are found to be more frequent in chronic obstructive pulmonary disease (COPD). The chronic systemic inflammation orchestrated by macrophages constitutes one critical pathophysiological process underlying both acute exacerbation of COPD (AECOPD) and its metabolic complications such as obesity and diabetes. The cyclic adenosine monophosphate (cAMP) signaling controlled by phosphodiesterase (PDE) 4 is a pivotal intracellular modulator for macrophages functions in immune inflammatory response underlying AECOPD as well as obesity and diabetes. Targeting PDE4/cAMP signaling has been suggested to be effective in treating AECOPD or the metabolic disorders of obesity and diabetes. It is therefore reasonable to hypothesize that the chronic systemic inflammation can be a critical link between AECOPD and the metabolic disorders and targeting the PDE4/cAMP signaling can be effective to block this link between AECOPD and the associated metabolic complications.
The Concept of “Developing Countries” in the Context of the WTO Fisheries Subsidies Negotiation  [PDF]
Youngjeen Cho
Beijing Law Review (BLR) , 2018, DOI: 10.4236/blr.2018.92010
Abstract: This paper explores the concept of developing countries in the context of the WTO DDA fisheries subsidies negotiations. It raises a question whether the concept of developing countries that is widely used in other WTO agreement should be applicable to the new disciplines on fisheries subsidies. In order to address the question, this paper outlines the history of the DDA fisheries subsidies negotiations and discusses the goal of fisheries subsidies negotiations. Then, it presents the concept of developing countries in the GATT, the WTO and other international institutions, and finds that it is almost exclusively based on economic indicators. Then, it reviews global fish production and the amount of global fisheries subsidies. On the basis of its analysis, this paper finds that, in order to achieve the proposed goal of the new disciplines on fisheries subsidies, and to strike a balance between the environmental and the developmental dimensions of fisheries subsidies, the concept of “developing countries” in the context of fisheries subsidies should be different from that in other WTO agreements. It should not include countries that have leading fishing industry for which the governments provide large amount of subsidies, in particular, fishing capacity-enhancing subsidies.
Individualized 3D Face Model Reconstruction using Two Orthogonal Face Images
SunHee Weon,SungIl Joo,HyungIl Choi
Lecture Notes in Engineering and Computer Science , 2012,
Abstract:
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