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Search Results: 1 - 10 of 432352 matches for " Sun M. Choi "
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New Forms of Place-Making and Public Space in Contemporary Urban Development in Seoul, South Korea  [PDF]
Hee Sun (Sunny) Choi
Current Urban Studies (CUS) , 2017, DOI: 10.4236/cus.2017.53018
Abstract: Place-making and its evolving role in urban design has become a major issue in setting the 21st century urban development agenda. A key aspect of this within South East and East Asia in particular is an apparent tension between global aspirations and local tradition in emerging states such as China, South Korea and Malaysia. The intention of this paper is to provide a better understanding of how new place making can be incorporated in contemporary urban development, particularly within this South East/East Asian context, so that the needs of local cultures can be sustained and developed, whilst acknowledging the desire of emerging states to gain international respect and recognition. The focus of this research is on exploring how these two views of design—the globally aspirational, and the locally situated and informed— might be reconciled, using the particular context of South Korea and the city of Seoul as a case study.
ComPath: comparative enzyme analysis and annotation in pathway/subsystem contexts
Kwangmin Choi, Sun Kim
BMC Bioinformatics , 2008, DOI: 10.1186/1471-2105-9-145
Abstract: ComPath allows users to compare biological pathways in multiple genomes using a spreadsheet style web interface where various sequence-based analysis can be performed either to compare enzymes (e.g. sequence clustering) and pathways (e.g. pathway hole identification), to search a genome for de novo prediction of enzymes, or to annotate a genome in comparison with reference genomes of choice. To fill in pathway holes or make de novo enzyme predictions, multiple computational methods such as FASTA, Whole-HMM, CSR-HMM (a method of our own introduced in this paper), and PDB-domain search are integrated in ComPath. Our experiments show that FASTA and CSR-HMM search methods generally outperform Whole-HMM and PDB-domain search methods in terms of sensitivity, but FASTA search performs poorly in terms of specificity, detecting more false positive as E-value cutoff increases. Overall, CSR-HMM search method performs best in terms of both sensitivity and specificity. Gene neighborhood and pathway neighborhood (global network) visualization tools can be used to get context information that is complementary to conventional KEGG map representation.ComPath is an interactive workbench for pathway reconstruction, annotation, and analysis where experts can perform various sequence, domain, context analysis, using an intuitive and interactive spreadsheet-style interface.Comparative analysis of multiple genomes has become a very important research method as more genome sequences become available. Biological pathway analysis is also typically performed in comparison with multiple genomes of choice, using a number of computational tools and databases. A biological pathway involves a number of enzymes and its substrates and products. In addition, pathways interact with each other. Thus comparative analysis of pathways is quite complicated and can hardly be done without well designed pathway analysis software systems. A number of automated pathway comparison systems have been developed: Th
Expression breadth and expression abundance behave differently in correlations with evolutionary rates
Seung Park, Sun Choi
BMC Evolutionary Biology , 2010, DOI: 10.1186/1471-2148-10-241
Abstract: In the present paper, we analyzed the relationship between the two expression variables and rates using two different genome-scale expression datasets, microarrays and ESTs. A significant positive correlation between the expression abundance (EA) and expression breadth (EB) was revealed by Kendall's rank correlation tests. A novel random shuffling approach was applied for EA and EB to compare the correlation coefficients obtained from real data sets to those estimated based on random chance. A novel method called a Fixed Group Analysis (FGA) was designed and applied to investigate the correlations between expression variables and rates when one of the two expression variables was evenly fixed.In conclusion, all of these analyses and tests consistently showed that the breadth rather than the abundance of gene expression is tightly linked with the evolutionary rate in multicellular organisms.Proteins in a species evolve at different rates [1]. The systems evolutionary genomics field studies the factors that determine the evolutionary rates of proteins. Over the last thirty years, since the neutral evolutionary theory was first suggested, a lack of sequence data prevented thorough investigation of protein evolution. One accepted consensus is that protein evolutionary rates are controlled by the density of amino acid residues in a protein under the influence of different functional constraints [2]. In other words, the functional importance of amino acid residues and their densities in a protein determine its evolutionary rate. This 'function-centered' hypothesis predicts several evolutionary outcomes. For example, proteins with high dispensability and a high propensity of gene loss (PGL) are expected to evolve more rapidly [3], whereas essential proteins and those at hub positions in a protein-protein interaction (PPI) network are predicted to evolve more slowly [4-6]. These hypotheses have been proven or disproven by various research groups through analyses of differen
Comparison and Analysis of Trisector Cell using Antenna Beam- width for CDMA Cellular Mobile Communication Systems
Noh Sun,Choi Dong
IETE Technical Review , 2010,
Abstract: The cell sectorization techniques are widely used in cellular systems to reduce co-channel interference by means of directional antennas. Cell sectorization and improvement of the chip energy/others -interference ratio (Ec /Io ) are technologies to offer good quality of services (QoSs) and coverage for new and -sophisticated power control to achieve high capacity. In this study, we analyze and compare performances of two -trisector cell architectures with different antenna beam-widths-a wide-beam trisector cell (WBTC) and a -narrow-beam trisector cell (NBTC)-in order to achieve effective cell sectoring in CDMA and cellular -mobile -communication systems. These architectures are outcomes of cell sectorization, which is widely employed in cellular -systems for reducing co-channel interference. We verify the effectiveness and validity of the NBTC -architecture by theoretically comparing it with the WBTC architecture (using parameters such as softer -handoff and -interference ratio). Further, we analyze results of a simulation of the WBTC and NBTC and of a field -measurement performed in Namwon city in Korea. From the analysis, we find that the NBTC -architecture is more efficient than the WBTC architecture in minimizing interference from adjacent BSs and increasing cell coverage while maintaining a good QoS.
Controversies on governing the rates of protein evolution
Sun Shim Choi
Interdisciplinary Bio Central , 2009,
Abstract: One of the main issues of molecular evolution is to reveal the principles dictating protein evolutionary rates. A traditional hypothesis posits that protein evolutionary rates are mostly determined by the average functional importance of amino acids in a given protein. Thus the correlations of evolutionary rates with different variables such as protein-protein interaction (PPI), gene essentiality and expression abundance have been studied to test the traditional hypothesis. Recently, mRNA expression abundance among the variables has drawn much attention, not only because it shows relatively strong correlation with protein evolutionary rates, but also because of the controversies surrounding an alternative hypothesis against the traditional one. Here, I will give an overview over the traditional hypothesis, and summarize the different variables that have been found to correlate with protein evolutionary rates. Then I will introduce pros and cons on the two different hypotheses.
Place Identity in 21st Century Architecture in South Korea
Hee Sun (Sunny) Choi
Archnet-IJAR : International Journal of Architectural Research , 2011,
Abstract:
Vascular lesions of the lumbar epidural space: magnetic resonance imaging features of epidural cavernous hemangioma and epidural hematoma
Basile Júnior, Roberto;Rosemberg, Laércio Alberto;Pedrosa, Fernando Machado;Uhlendorff, Eduardo Von;Matuoka, Claudia M.;Choi, Pil Sun;
Revista do Hospital das Clínicas , 1999, DOI: 10.1590/S0041-87811999000100006
Abstract: the authors report the magnetic resonance imaging diagnostic features in two cases with respectively lumbar epidural hematoma and cavernous hemangioma of the lumbar epidural space. enhanced mri t1-weighted scans show a hyperintense signal rim surrounding the vascular lesion. non-enhanced t2-weighted scans showed hyperintense signal.
Pauli paramagnetism of an ideal Fermi gas
Ye-Ryoung Lee,Tout T. Wang,Timur M. Rvachov,Jae-Hoon Choi,Wolfgang Ketterle,Myoung-Sun Heo
Physics , 2013, DOI: 10.1103/PhysRevA.87.043629
Abstract: We show how to use trapped ultracold atoms to measure the magnetic susceptibility of a two-component Fermi gas. The method is illustrated for a non-interacting gas of $^6$Li, using the tunability of interactions around a wide Feshbach resonances. The susceptibility versus effective magnetic field is directly obtained from the inhomogeneous density profile of the trapped atomic cloud. The wings of the cloud realize the high field limit where the polarization approaches 100%, which is not accessible for an electron gas.
Iron pnictides: Single crystal growth and effect of doping on structural, transport and magnetic properties
G. L. Sun,D. L. Sun,M. Konuma,P. Popovich,A. Boris,J. B. Peng,K. -Y. Choi,P. Lemmens,C. T. Lin
Physics , 2009, DOI: 10.1007/s10948-010-1123-z
Abstract: We demonstrate the preparation of large, free standing iron pnictide single crystals with a size up to 20 x 10 x 1 mm3 using solvents in zirconia crucibles under argon atmosphere. Transport and magnetic properties are investigated to study the effect of potassium doping on the structural and superconducting property of the compounds. The spin density wave (SDW) anomaly at Ts ~138 K in BaFe2As2 single crystals from self-flux shifts to Ts ~85 K due to Sn solvent growth. We show direct evidence for an incorporation of Sn on the Fe site. The electrical resistivity data show a sharp superconducting transition temperature Tc~38.5 K for the single crystal of Ba0.68K0.32Fe2As2. A nearly 100% shielding fraction and bulk nature of the superconductivity for the single crystal were confirmed by magnetic susceptibility data. A sharp transition Tc~25 K occurred for the single crystal of Sr0.85K0.15Fe2As2. There is direct evidence for a coexistence of the SDW and superconductivity in the low doping regime of Sr1-xKxFe2As2 single crystals. Structural implications of the doping effects as well as the coexistence of the two order parameters are discussed.
Stability and ensemble inequivalence in a globally coupled system
M. Y. Choi,J. Choi
Physics , 2003, DOI: 10.1103/PhysRevLett.91.124101
Abstract: We consider a system of globally coupled rotors, described by a set of Langevin equations, and examine stability of the incoherent phase. The corresponding Fokker-Planck equation, providing a unified description of microcanonical and canonical ensembles, bears a few solutions, depending upon the ensemble. It is found that the stability of each solution varies differently with the temperature, revealing the inequivalence between the two ensembles. This also suggests a physical explanation of the quasi-stationarity observed in recent numerical results.
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