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Search Results: 1 - 10 of 261 matches for " Sujatha Madireddi "
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A Dysmorphic Child with a Pericentric Inversion of Chromosome 8
Venkateshwari Ananthapur,Srilekha Avvari,Sujatha Madireddi,Pratibha Nallari,Jyothy Akka
Case Reports in Pediatrics , 2012, DOI: 10.1155/2012/813963
Abstract: An 8-year-old boy was referred to our institute with dysmorphic features such as mild lupus, micrognathia, low hair line, hypoplasia, hemi atrophy of left side of the face, abnormal size of ears, hypothenar, hypoplasia of chin, and tongue tie. MRI scan was found to be normal and EEG suggestive of generalized seizure disorder. Cytogenetic evaluation of the proband revealed a pericentric inversion of chromosome 8 with 46, XY, and inv 8 (p11.2; q21.2) karyotype.
A Dysmorphic Child with a Pericentric Inversion of Chromosome 8
Venkateshwari Ananthapur,Srilekha Avvari,Sujatha Madireddi,Pratibha Nallari,Jyothy Akka
Case Reports in Pediatrics , 2012, DOI: 10.1155/2012/813963
Abstract: An 8-year-old boy was referred to our institute with dysmorphic features such as mild lupus, micrognathia, low hair line, hypoplasia, hemi atrophy of left side of the face, abnormal size of ears, hypothenar, hypoplasia of chin, and tongue tie. MRI scan was found to be normal and EEG suggestive of generalized seizure disorder. Cytogenetic evaluation of the proband revealed a pericentric inversion of chromosome 8 with 46, XY, and inv 8 (p11.2; q21.2) karyotype. 1. Introduction Pericentric inversions are among the frequent chromosomal rearrangements associated with genetic disorders with a frequency of 1-2% [1, 2]. Pericentric inversions result from a two-break event which occurs between the short (p) and the long arms (q) within the chromosome followed by a 180° rotation of the intercalary segment. The phenotype of the inversion carrier depends on the type of inversion, size of the inverted part, and the chromosome involved [3]. In this report, we describe the distinct clinical phenotype and the karyotype of a boy with dysmorphic facial features and mild mental retardation associated with a pericentric inversion of chromosome 8. 2. Case Report An 8-year-old male child with dysmorphic facies and mild mental retardation was referred to the Institute of Genetics, Hyderabad for cytogenetic evaluation. He was born after full term as the third child in the sibship of nonconsanguineous parents. He had delayed developmental milestones, neck holding at the age of 5 months, walking independently at the age of 2 years and 5 months, and started speech at the age of 3 years and 5 months. The dysmorphic facial features included mild lupeus, micrognathia, low-hair line, hypoplasia, hemiatrophy of left side of the face, abnormal size of ears, hypothenar, hypoplasia of chin, and tongue tie. His external genitalia were normal. Psychological evaluation of the child was carried out using Senguin form board and Vineland Social maturity physical examination scale [4]. The intelligent quotient was found to be 64 indicative of mild mental retardation. MRI Scan report of the propositus was normal, but his EEG study was suggestive of generalized seizure disorder. He had hyperactive behavior with slurred speech. It is informed that the boy was frightened by loud sounds and is presently attending a special school. Chromosomal analysis of peripheral blood lymphocytes was performed using GTG banding for the propositus and their parents [5, 6]. A rearranged chromosome was observed in the propositus with pericentric inversion of chromosome 8 with break point at p 11.2 and q 21.2 regions
A Novel Validated Stability Indicative UP-LC Method for Etravirine for the Determination of Process Related and Degradation Impurities  [PDF]
Mohanareddy Chilukuri, Katreddi H. Reddy, Papadasu Narayanareddy, Madireddi Venkataramana
American Journal of Analytical Chemistry (AJAC) , 2012, DOI: 10.4236/ajac.2012.312111
Abstract: A novel stability indicating reverse phase ultra performance liquid chromatographic (UP-LC) method has been developed for Etravirine along with eight impurities (imp-1, imp-2, imp-3, imp-4, imp-5, imp-6, imp-7 and imp-8) and validated as per ICH recommendations. Stress degradation conditions were established for Etravirine by subjecting it to stress conditions of acid, base, oxidation, humidity, thermal and photolysis. Significant degradation is observed in base stress condition and the major degradant (RRT at about 0.94) is identified by LC-MS and spectral analysis. The stress samples were assayed against a qualified reference standard and the mass balance was found close to 99.0%. Efficient chromatographic separation was achieved on a Shimpack ODS-II stationary phase with a gradient mobile phase combination. Quantification was carried at 303 nm at a flow rate of 0.6 mL?min–1. The resolution between Etravirine and eight potential impurities is found to be greater than 2.0. Regression analysis shows as r value (correlation coefficient) of greater than 0.999 for Etravirine and eight potential impurities. This method is capable to detect the impurities of Etravirine at a level of 0.003% with respect to test concentration of 1.0 mg·mL–1.
Zeeman-Like Topologies in Special and General Theory of Relativity  [PDF]
Ravindra Saraykar, Sujatha Janardhan
Journal of Modern Physics (JMP) , 2016, DOI: 10.4236/jmp.2016.77063
Abstract: This is a short review article in which we discuss and summarize the works of various researchers over past four decades on Zeeman topology and Zeeman-like topologies, which occur in special and general theory of relativity. We also discuss various properties and inter-relationship of these topologies.
Neural Network Based Normalized Fusion Approaches for Optimized Multimodal Biometric Authentication Algorithm  [PDF]
E. Sujatha, A. Chilambuchelvan
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.78103
Abstract: A multimodal biometric system is applied to recognize individuals for authentication using neural networks. In this paper multimodal biometric algorithm is designed by integrating iris, finger vein, palm print and face biometric traits. Normalized score level fusion approach is applied and optimized, encoded for matching decision. It is a multilevel wavelet, phase based fusion algorithm. This robust multimodal biometric algorithm increases the security level, accuracy, reduces memory size and equal error rate and eliminates unimodal biometric algorithm vulnerabilities.
Implementation of Adaptive Neuro Fuzzy Inference System in Speed Control of Induction Motor Drives  [PDF]
K. Naga Sujatha, K. Vaisakh
Journal of Intelligent Learning Systems and Applications (JILSA) , 2010, DOI: 10.4236/jilsa.2010.22014
Abstract: A new speed control approach based on the Adaptive Neuro-Fuzzy Inference System (ANFIS) to a closed-loop, variable speed induction motor (IM) drive is proposed in this paper. ANFIS provides a nonlinear modeling of motor drive system and the motor speed can accurately track the reference signal. ANFIS has the advantages of employing expert knowledge from the fuzzy inference system and the learning capability of neural networks. The various functional blocks of the system which govern the system behavior for small variations about the operating point are derived, and the transient responses are presented. The proposed (ANFIS) controller is compared with PI controller by computer simulation through the MATLAB/SIMULINK software. The obtained results demonstrate the effectiveness of the proposed control scheme.
Everyday Wars of Position: Social Movements and the Caracas Barrios in a Chávez Era
Fernandes,Sujatha;
Colombia Internacional , 2011,
Abstract: this article identifies the ways that urban social movements in caracas have sought to engage the hybrid state during the presidency of radical leftist leader hugo chávez. chávez's election has created avenues for previously disenfranchised groups to participate in gover-nance and decision-making. the structures and discourses of exclusion are being contested in multiple arenas since chávez has come to power. but, what lines of conflict are emerging as barrio-based movements demand inclusion in the state? in this article, i argue that as urban movements engage with the political arena, they come up against the instrumental rationalities-both liberal and neoliberal-of state administrators. barrio-based social movements counter the utilitarian logics of technocrats with alternative visions based in "lo cotidiano" (the everyday), local culture and historical memory. we need to combine foucault's insights about the operation of power through governmentality with gramsci's insistence on practical politics, in order to account more fully for the contested nature of power. in this article, i suggest the reframing of a gramscian notion of hegemony in a positive sense as "everyday wars of position," to think about the quotidian and subterranean spaces where technocrats are confronted with alternative visions from below. i use the example of com-munity media in caracas to illustrate the ways that social movements engage with the state.
Phthiriasis palpebrarum
Sujatha Vijayalekshmi
Our Dermatology Online , 2012,
Abstract: Phthiriasis palpebrarum of the eyelashes is not an uncommon condition when hygienic condition are inadequate. The lice occupy, chiefly, the roots of the eyelashes, to which they cling tenaciously, while the shafts of the cilia are covered with their brown nits. The patients with the symptom of pruritus of the eyelids and with clinical findings resembling exfoliation on the surface of lid skin and seborrhea accumulation on eyelashes must carefully be examined by slit lamp in order to avoid misdiagnosis. In the cases diagnosed as having lid eczema and seborrheic blepharitis, lice and nits might easily be overlooked and treatment might remain ineffective. Various treatment options are available from medical; mechanical removal of nits and lice, cryotherapy. In this short review we are describing in details about the organism, clinical features, mode of transmission, treatment about Phthiriasis palpebrarum.
Improving the QOS in Video Streaming Multicast
Sujatha M.
Indian Journal of Computer Science and Engineering , 2011,
Abstract: In a streaming video multicast environment a large number of users often request various similar processing on the same stream. Therefore service sharing is feasible, with a large potential of savings in processing cost.The Service invocation order may play a significant role on service sharing in a streaming video multicast application. The problem is how to determine Service Invocation Order for multiple service composition requests with the aim of maximizing service sharing. This paper proposes BFS algorithm to maximize the service sharing in a streaming video multicast environment in order to reduce the processing cost and to increase the scalability. The service invocation orders for multiple service composition requests will be determined with the aim of maximizing the service sharing. The BFS algorithm merges the services level by level without changing the service invocation order.
A Letter
Sujatha S
Indian Journal of Ophthalmology , 2003,
Abstract:
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