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Search Results: 1 - 10 of 3701 matches for " Sudhanshu Shanker2 "
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Hidden markov model for the prediction of transmembrane proteins using MATLAB
Navaneet Chaturvedi*,Vinay Kumar Singh3,Sudhanshu Shanker2,Dhiraj Sinha4
Bioinformation , 2011,
Abstract: Since membranous proteins play a key role in drug targeting therefore transmembrane proteins prediction is active and challenging area of biological sciences. Location based prediction of transmembrane proteins are significant for functional annotation of protein sequences. Hidden markov model based method was widely applied for transmembrane topology prediction. Here we have presented a revised and a better understanding model than an existing one for transmembrane protein prediction. Scripting on MATLAB was built and compiled for parameter estimation of model and applied this model on amino acid sequence to know the transmembrane and its adjacent locations. Estimated model of transmembrane topology was based on TMHMM model architecture. Only 7 super states are defined in the given dataset, which were converted to 96 states on the basis of their length in sequence. Accuracy of the prediction of model was observed about 74 %, is a good enough in the area of transmembrane topology prediction. Therefore we have concluded the hidden markov model plays crucial role in transmembrane helices prediction on MATLAB platform and it could also be useful for drug discovery strategy.
Versatile Voltage-Mode Universal Filter Using Differential Difference Current Conveyor  [PDF]
Sudhanshu Maheshwari, Ankita Gangwar
Circuits and Systems (CS) , 2011, DOI: 10.4236/cs.2011.23030
Abstract: A novel four-input three-output voltage-mode differential difference current conveyor (DDCC) based universal filter is presented. The circuit uses three DDCCs as active elements, two resistors and two capacitors as passive elements. The circuit along with its versatility enjoys the advantage of minimum number of passive elements employment. SPICE simulation results are given to confirm the theoretical analysis. The proposed circuit is a novel addition to the existing knowledge on the subject.
A Two-Parameter Lindley Distribution for Modeling Waiting and Survival Times Data  [PDF]
Rama Shanker, Shambhu Sharma, Ravi Shanker
Applied Mathematics (AM) , 2013, DOI: 10.4236/am.2013.42056

In this paper, a two-parameter Lindley distribution, of which the one parameter Lindley distribution (LD) is a particular case, for modeling waiting and survival times data has been introduced. Its moments, failure rate function, mean residual life function, and stochastic orderings have been discussed. It is found that the expressions for failure rate function mean residual life function and stochastic orderings of the two-parameter LD shows flexibility over one-parameter LD and exponential distribution. The maximum likelihood method and the method of moments have been discussed for estimating its parameters. The distribution has been fitted to some data-sets relating to waiting times and survival times to test its goodness of fit to which earlier the one parameter LD has been fitted by others and it is found that to almost all these data-sets the two parameter LD distribution provides closer fits than those by the one parameter LD.

Unsteady Boundary Layer Flow and Heat Transfer Due to a Stretching Sheet by Quasilinearization Technique  [PDF]
Wubshet Ibrahim, Bandari Shanker
World Journal of Mechanics (WJM) , 2011, DOI: 10.4236/wjm.2011.16036
Abstract: In this paper, the problem of unsteady laminar boundary-layer flow and heat transfer of a viscous income-pressible fluid over stretching sheet is studied numerically. The unsteadiness in the flow and temperature is caused by the time-dependent stretching velocity and surface temperature. A similarity transformation is used to reduce the governing boundary-layer equations to couple higher order non-linear ordinary differential equations. These equations are numerically solved using quasi-linearization technique. The effect of the governing parameters unsteadiness parameter and Prandtl number on velocity and temperature profile is discussed. Besides the numerical results for the local skin friction coefficient and local Nusselt number are presented. The computed results are compared with previously reported work.
Mixed Convection MHD Flow of a Casson Nanofluid over a Nonlinear Permeable Stretching Sheet with Viscous Dissipation  [PDF]
Prabhakar Besthapu, Shanker Bandari
Journal of Applied Mathematics and Physics (JAMP) , 2015, DOI: 10.4236/jamp.2015.312182
Abstract: The present study deals with the mixed convection MHD flow of a Casson nanofluid over a nonlinear permeable stretching sheet with viscous dissipation. The governing partial differential equations are transformed into nonlinear coupled ordinary differential equations with the help of suitable similarity transformations. These equations were then solved numerically by using an implicit finite difference method known as Keller-Box method. The effects of various parameters such as magnetic parameter (M), Casson parameter (β), local Grashoff number (Gr), local modified Grashoff number (Gc), nonlinear parameter (n), Eckert number (Ec) on velocity, temperature and concentration were discussed and presented graphically. It is found that a larger value of Casson parameter leads to decrease the velocity and temperature. Increase in the local Grashoff number reduces the temperature. Nanoparticle concentration is decreased for the larger values of local Modified Grashoff number. The numerical values of skin friction, Nusselt number and Sherwood number are presented in tables.
Active-Only Current Controlled Summing/Difference Amplifiers Using CCCIIs
Sudhanshu Maheshwari
Active and Passive Electronic Components , 2003, DOI: 10.1080/0882751031000116151
Abstract: Novel active-only summing/difference amplifiers employing only current controlled conveyors (CCCIIs) are presented. The circuits possess high input impedance, current controllable gain, good linearity and dynamic range, low THD and are suited for IC implementation. SPICE simulation results are included to verify the circuits.
Voltage-Mode All-Pass Filters Including Minimum Component Count Circuits
Sudhanshu Maheshwari
Active and Passive Electronic Components , 2007, DOI: 10.1155/2007/79159
Abstract: This paper presents two new first-order voltage-mode all-pass filters using a single-current differencing buffered amplifier and four passive components. Each circuit is compatible to a current-controlled current differencing buffered amplifier with only two passive elements, thus resulting in two more circuits, which employ a capacitor, a resistor, and an active element, thus using a minimum of active and passive component counts. The proposed circuits possess low output impedance, and hence can be easily cascaded for voltage-mode systems. PSPICE simulation results are given to confirm the theory.
Electronically Tunable Quadrature Oscillator Using Translinear Conveyors and Grounded Capacitors
Sudhanshu Maheshwari
Active and Passive Electronic Components , 2003, DOI: 10.1080/0882751031000116179
Abstract: A new electronically tunable current-mode sinusoidal oscillator with three quadrature outputs is presented. The proposed circuit employs three translinear conveyors and two grounded capacitors to realize three quadrature outputs with independent frequency control. The circuit requires no resistors and the frequency of the oscillator can be varied over a wide range by external current control. RSPICE simulation results using the bipolar implementation of translinear conveyors are given to support the proposed circuit.
Age estimation of indian adults from orthopantomographs
Saxena, Sudhanshu;
Brazilian Oral Research , 2011, DOI: 10.1590/S1806-83242011005000009
Abstract: the aim of this study was to develop a method for estimating the chronological age of indian adults based on the relationship between age and various morphological variables of canine teeth, obtained using orthopantomographs. orthopantomographs of 120 selected patients were digitized, and radiographic images of the right maxillary canine in each case were processed using a computer aided drafting program. pulp/tooth area ratio, pulp/root length ratio, pulp/tooth length ratio, pulp/root width ratio at the cemento-enamel junction level, pulp/root width ratio at midroot level, and pulp/root width ratio at the midpoint between the cemento-enamel junction and the midroot of the canine were calculated by measuring various features on the images. pearson's correlation, multiple linear regression, one way analysis of variance (anova), and student's t-test were used for statistical analysis. regression equations were developed to estimate age from morphological variables. the observed minus the estimated age in the total study sample ranged from -2.2 to +1.5 years, in males from -0.9 to +0.8 years, while in females it was from -1 to +0.8 years. differences between observed and estimated ages of subjects were not statistically significant. in conclusion there is a linear relationship of pulp/root width ratio at mid-root level and pulp/tooth area ratio of the right maxillary canine with chronological age in the indian population. age of subjects can therefore be estimated with a good degree of accuracy using regression equations.
Online Non Destructive Evaluation of Large Pipe Lines and Cylindrical Structures Using Guided Ultrasonic Wave Diffraction Tomography
Sudhanshu Shekhar
International Journal of Engineering and Advanced Technology , 2012,
Abstract: This Research work evaluates the ability of ultrasonic guided waves to detect several types of defects in cylindrical structures with different pre-selected wave modes. It will also demonstrate ultrasonic guided wave method [1& 2] as an alternative to standard ultrasonic techniques and how to address their deficiencies. This approach is based on the use of ultrasonic guided waves. In this work the use of ultrasonic guided waves for thickness mapping of large, partially accessible areas was investigated. The problem of interest is to evaluate the minimum remaining plate thickness over a large area. Guided waves [3 & 4] have multiple properties that can be used for thickness mapping over large areas. Firstly, the dispersive nature and variation of the phase velocity as a function of the frequency thickness product of guided waves [5 &6] make them potentially suitable for thickness mapping by time-of-flight tomography and diffraction tomography based on the variation of the velocity in the in homogeneities [7] . The experimental result was validated with FE (Finite Element) profile to arrive at the conclusion. Diffraction tomography can reconstruct a map of the velocity from the scattered field produced by the interaction of an incoming wave field and a velocity in homogeneity. It has been shown that Diffraction tomography with low frequency guided waves can be used for thickness reconstruction of plates or large diameter pipes. Low frequency guided waves can be used for thickness reconstruction of plates or large diameter pipes. It has been shown that the scattering from the array of transducers needs to be minimized in order to reconstruct thickness accurately. However when the scattering from the array of transducers is large it is possible to use guided wave diffraction tomography in a structural health monitoring approach and obtain accurate thickness reconstruction
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