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Search Results: 1 - 10 of 20957 matches for " Su Jung Baik "
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Seroprevalence of Helicobacter pylori in female Vietnamese immigrants to Korea
Su Jung Baik,Sun Young Yi,Hye Sook Park,Bo Hyun Park
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i6.517
Abstract: AIM: To investigate the seroprevalence of Helicobacter pylori (H. pylori) and its relationship to nutritional factors in female Vietnamese immigrants to Korea. METHODS: A total of 390 female immigrants from Vietnam and 206 Korean male spouses participated in the study. Blood samples from 321 female immigrants and 201 Korean male spouses were analyzed for H. pylori antibodies. Data on age, sex, alcohol consumption, smoking status, dietary nutritional factors and gastrointestinal symptoms were collected using questionnaires. The daily intakes of the following nutrients were estimated: energy, protein, niacin, lipid, fiber, calcium, iron, sodium, potassium, zinc, folate, cholesterol, and vitamins A, B1, B2, B6, C and E. RESULTS: The prevalence of H. pylori positivity was lower in the immigrants than in age-matched Korean females (55.7% vs 71.4%, respectively; P < 0.0001) and the domestic population of Vietnam. The prevalence of H. pylori positivity among married couples was 31.7% for both spouses. There were no statistically significant differences in the incidence of smoking, amount of alcohol consumed, or nutritional factors between the H. pylori-positive and negative groups. CONCLUSION: The prevalence of H. pylori positivity was lower among female Vietnamese immigrants than among Korean females. Nutritional factors did not differ between the H. pylori-positive and negative groups.
Ischemic colitis during interferon-ribavirin therapy for chronic hepatitis C: A case report
Su Jung Baik,Tae Hun Kim,Kwon Yoo,Il Hwan Moon
World Journal of Gastroenterology , 2012, DOI: 10.3748/wjg.v18.i31.4233
Abstract: Ischemic colitis is a rare complication of interferon administration. Only 9 cases in 6 reports have been described to-date. This report describes a case of ischemic colitis during pegylated interferon and ribavirin treatment for chronic hepatitis C, and includes a review of the relevant literature. A 48-year-old woman was treated with pegylated interferon α-2a and ribavirin for chronic hepatitis C, genotype Ib. After 19 wk of treatment, the patient complained of severe afebrile abdominal pain with hematochezia. Vital signs were stable and serum white blood cell count was within the normal range. Abdominal computed tomography showed diffuse colonic wall thickening from the splenic flexure to the proximal sigmoid colon, which is the most vulnerable area for the development of ischemic colitis. Colonoscopy revealed an acute mucosal hyperemic change, with edema and ulcerations extending from the proximal descending colon to the sigmoid colon. Colonic mucosal biopsy revealed acute exudative colitis. Polymerase chain reaction and culture for Mycobacterium tuberculosis were negative and the cultures for cytomegalovirus, Salmonella and Shigella species were negative. After discontinuation of interferon and ribavirin therapy, abdominal pain and hematochezia subsided and, following colonoscopy showed improvement of the mucosal ulcerations. Ischemic colitis cases during interferon therapy in patients with chronic hepatitis C reported so far have all involved the descending colon. Ischemic colitis is a rarely encountered complication of interferon administration in patients with chronic hepatitis C and should be considered when a patient complains of abdominal pain and hematochezia.
Reinfection rate and endoscopic changes after successful eradication of Helicobacter pylori
Kum Hei Ryu, Sun Young Yi, Youn Ju Na, Su Jung Baik, Su Jin Yoon, Hae-Sun Jung, Hyun Joo Song
World Journal of Gastroenterology , 2010,
Abstract: AIM: To determine the long-term outcomes regarding reinfection with Helicobacter pylori (H. pylori) and endoscopic changes after successful H. pylori eradication.METHODS: From June 1994 to January 2007, 186 patients (M:F = 98:88; mean age 50.0 ± 11.4 years), in whom H. pylori had been successfully eradicated, were enrolled. The mean duration of follow up was 41.2 ± 24.0 mo.RESULTS: H. pylori reinfection occurred in 58 patients (31.2%). The average annual reinfection rate was 9.1% per patient year. No recurrence of peptic ulcer was detected at the follow up endoscopy. There were no significant differences between the H. pylori eradication regimens for the reinfection rate and no significant differences in endoscopic findings between the H. pylori-recurred group and the H. pylori-cured group.CONCLUSION: The reinfection rate in Korea is 9.1% which represents a decreasing trend. There was no relationship between H. pylori infection status and changes in endoscopic findings. There was also no recurrence or aggravation of ulcers.
Causal relay networks
Ihn-Jung Baik,Sae-Young Chung
Mathematics , 2012,
Abstract: In this paper, we study causal discrete-memoryless relay networks (DMRNs). The network consists of multiple nodes, each of which can be a source, relay, and/or destination. In the network, there are two types of relays, i.e., relays with one sample delay (strictly causal) and relays without delay (causal) whose transmit signal depends not only on the past received symbols but also on the current received symbol. For this network, we derive two new cut-set bounds, one when the causal relays have their own messages and the other when not. Using examples of a causal vector Gaussian two-way relay channel and a causal vector Gaussian relay channel, we show that the new cut-set bounds can be achieved by a simple amplify-and-forward type relaying. Our result for the causal relay channel strengthens the previously known capacity result for the same channel by El Gamal, Hassanpour, and Mammen.
Efficacy of Single Dose of a Bivalent Vaccine Containing Inactivated Newcastle Disease Virus and Reassortant Highly Pathogenic Avian Influenza H5N1 Virus against Lethal HPAI and NDV Infection in Chickens
Dong-Hun Lee, Jae-Keun Park, Jung-Hoon Kwon, Seong-Su Yuk, Tseren-Ochir Erdene-Ochir, Yo-Han Jang, Baik-Lin Seong, Joong-Bok Lee, Seung-Yong Park, In-Soo Choi, Chang-Seon Song
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0058186
Abstract: Highly pathogenic avian influenza (HPAI) and Newcastle disease (ND) are 2 devastating diseases of poultry, which cause great economic losses to the poultry industry. In the present study, we developed a bivalent vaccine containing antigens of inactivated ND and reassortant HPAI H5N1 viruses as a candidate poultry vaccine, and we evaluated its immunogenicity and protective efficacy in specific pathogen-free chickens. The 6:2 reassortant H5N1 vaccine strain containing the surface genes of the A/Chicken/Korea/ES/2003(H5N1) virus was successfully generated by reverse genetics. A polybasic cleavage site of the hemagglutinin segment was replaced by a monobasic cleavage site. We characterized the reverse genetics-derived reassortant HPAI H5N1 clade 2.5 vaccine strain by evaluating its growth kinetics in eggs, minimum effective dose in chickens, and cross-clade immunogenicity against HPAI clade 1 and 2. The bivalent vaccine was prepared by emulsifying inactivated ND (La Sota strain) and reassortant HPAI viruses with Montanide ISA 70 adjuvant. A single immunization with this vaccine induced high levels of hemagglutination-inhibiting antibody titers and protected chickens against a lethal challenge with the wild-type HPAI and ND viruses. Our results demonstrate that the bivalent, inactivated vaccine developed in this study is a promising approach for the control of both HPAI H5N1 and ND viral infections.
Characterization of vaccinia virus A12L protein proteolysis and its participation in virus assembly
Su Jung Yang
Virology Journal , 2007, DOI: 10.1186/1743-422x-4-78
Abstract: Vaccinia virus (VV), the prototype member of the Poxviridae family has a large double-stranded DNA genome. Replication and viral assembly occur entirely in the cytoplasm of host cells, in particular, in areas referred as viroplasms or virosomes. Virus assembly initiates at virosomes surrounded by crescent membranes, which subsequently engulf granular materials forming spherical-shaped particles named immature virions (IV). The IVs transform into brick-shaped structures referred to as intracellular mature virions (IMV) where viral DNAs become condensed and packaged in an electron dense area and are covered by a viral envelope membrane. A portion of IMVs is enwrapped by a membrane cisternae derived from the trans-Golgi network and results in the formation of intracellular enveloped virus (IEV), which then becomes fused with the plasma membrane. If the IEVs remain associated with the cells, they are referred to as cell-associated enveloped virus (CEV), or if the IEVs bud through the plasma membrane spreading outside of the cells, they are considered extracellular enveloped virus (EEV).Despite intensive study of VV morphogenesis, the mechanism required for the transformation of IV to IMV still remains poorly understood. The complex morphological development during the transition initiates with successful DNA replication, concatermer resolution [1,2] and condensation/packaging of the viral genome in IV particles [3]. This is followed by encapsidation of a transcription complex, formation of a defined core, and reorganization of virion membranes [4]. In order to complete this morphogenic transformation, VV undergoes a various post-translational modifications such as proteolytic processing of VV structural proteins, which contributes to proper virus morphogenic development and acquisition of viral infectivity.The cleavage processing of VV structural precursor proteins are well studied. The cleavage reactions take place after the second Gly residue of an Ala-Gly-X (AG/X) co
Challenges in epidemiological and statistical evaluations of effect modifiers and confounders
Su Yon Jung
Frontiers in Public Health , 2014, DOI: 10.3389/fpubh.2014.00277
Abstract: In multiple adjusted regression models, researchers sometimes do not know when the interaction occurs and how to interpret the exposure effect estimate while adjusting for the interaction term, resulting in a misinterpretation of the results; this issue has been raised in previous epidemiologic studies. In addition, when the positions of exposure and outcome are switched in the multiple regression, interpreting covariates is challenging. Here, we present the epidemiological and statistical challenges in evaluating the effect modifier and confounding factor. 1. When does the interaction occur? As an example to illustrate aspects of the evaluation of interaction, we describe below. In our example, we want to determine whether radon exposure (the third factor) is an effect modifier in the relationship between smoking (exposure) and lung cancer (outcome). For a dichotomous potential modifier (radon exposure [yes/no]), the interaction occurs when the effect of the exposure (smoking) on the outcome (lung cancer) is not homogenous in strata formed by a third variable (radon exposure).1-3 The effect can be measured either by the attributable risk (in the additive model) or by a relative risk (in the multiplicative model); both models share the same conceptual basis for evaluating the interaction.1,2 To measure the effect of the interaction between smoking and lung cancer, we set the simple regression model and added a third variable, radon exposure, along with an interaction term of radon exposure with smoking (i.e., radon*smoking). The regression model is shown below. Y(lung cancer) = BsXsmoking + BrXradon exposure + BsrXsmoking*radon exposure, Where Bs is the effect of Xsmoking, Br is the effect of Xradon exposure, and Bsr is the effect of Xsmoking*radon exposure. The most important issue in this model for determining whether or not radon exposure is an effect modifier is to interpret the effect size (i.e., Bsr); that is, rather than focusing on only the "p-value" of the effect size, researchers should concentrate on the magnitude of the interaction term. In addition, when outcome variables are continuous and the levels of a continuous variable are small (e.g., 0.01, 0.02, and 0.03), the effect size of the interaction can be small resulting in a small slope in a graph composed of an x-axis for exposure and a y-axis for outcome. This occurs as a result of the tiny interval between outcome variable numerals; it does not suggest that there is no interaction. In this case, we can graphically test the interaction by plotting the means of the outcome variables for
Sublingual Immunization with M2-Based Vaccine Induces Broad Protective Immunity against Influenza
Byoung-Shik Shim, Young Ki Choi, Cheol-Heui Yun, Eu-Gene Lee, Yoon Seong Jeon, Sung-Moo Park, In Su Cheon, Dong-Hyun Joo, Chung Hwan Cho, Min-Suk Song, Sang-Uk Seo, Young-Ho Byun, Hae-Jung Park, Haryoung Poo, Baik Lin Seong, Jae Ouk Kim, Huan Huu Nguyen, Konrad Stadler, Dong Wook Kim, Kee-Jong Hong, Cecil Czerkinsky, Man Ki Song
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0027953
Abstract: Background The ectodomain of matrix protein 2 (M2e) of influenza A virus is a rationale target antigen candidate for the development of a universal vaccine against influenza as M2e undergoes little sequence variation amongst human influenza A strains. Vaccine-induced M2e-specific antibodies (Abs) have been shown to display significant cross-protective activity in animal models. M2e-based vaccine constructs have been shown to be more protective when administered by the intranasal (i.n.) route than after parenteral injection. However, i.n. administration of vaccines poses rare but serious safety issues associated with retrograde passage of inhaled antigens and adjuvants through the olfactory epithelium. In this study, we examined whether the sublingual (s.l.) route could serve as a safe and effective alternative mucosal delivery route for administering a prototype M2e-based vaccine. The mechanism whereby s.l. immunization with M2e vaccine candidate induces broad protection against infection with different influenza virus subtypes was explored. Methods and Results A recombinant M2 protein with three tandem copies of the M2e (3M2eC) was expressed in Escherichia coli. Parenteral immunizations of mice with 3M2eC induced high levels of M2e-specific serum Abs but failed to provide complete protection against lethal challenge with influenza virus. In contrast, s.l. immunization with 3M2eC was superior for inducing protection in mice. In the latter animals, protection was associated with specific Ab responses in the lungs. Conclusions The results demonstrate that s.l. immunization with 3M2eC vaccine induced airway mucosal immune responses along with broad cross-protective immunity to influenza. These findings may contribute to the understanding of the M2-based vaccine approach to control epidemic and pandemic influenza infections.
Foodservice Quality: Identifying Perception Indicators of Foodservice Quality for Hospitality Students  [PDF]
Wen-Hwa Ko, Li-Jung Su
Food and Nutrition Sciences (FNS) , 2014, DOI: 10.4236/fns.2014.52017

This study uses an expert perspective to identify indicators of foodservice quality as perceived by hospitality students. A 3-round modified Delphi method and an expert panel comprising culinary arts instructors, master chefs with >10 years of experience, and senior foodservice industry executive managers were used to define and identify these indicators. The developed foodservice quality framework includes 2 categories, the product and customer, which comprise 57 indicators in 6 dimensions. The results of this study provide a clear direction for further studies and applications for hospitality professionals, educators, and students.

Study on Design of Pressure Chamber in a Linear-Jet Type Air Curtain System for Prevention of Smoke Spread  [PDF]
Jung-Yup Kim, Su-Gak Lee
Open Journal of Fluid Dynamics (OJFD) , 2017, DOI: 10.4236/ojfd.2017.74034
Death toll by smoke in fire is estimated at 70% which emphasizes the importance of smoke control system to deal with the fire smoke. In advanced countries, the studies on method to prevent smoke spread by forming the air curtain using high velocity jet flow are underway now. In this study, a linear-jet type air curtain system is proposed to prevent the smoke spread and analysis of flow characteristics of pressure chamber, which is the core component, is conducted through numerical analysis and experimental approach. Consequently, the pressure was increased in 2D functional way to input air flowrate and about 595 Pa pressure was formed at pressure chamber inlet in response to 30 m/s nozzle jet velocity.
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